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Check prices for these dates

In two weeks
20 Nov - 22 Nov
In two months
1 Jan - 3 Jan
In three months
29 Jan - 31 Jan
In four months
26 Feb - 28 Feb

Our top choices for Santa Cruz holiday rentals

A modern hotel corridor with a glass wall displaying multilingual greetings, a staircase, and a clean, tiled floor.

1. A30 Plaza Acequia Suite Black Plus

A30 Plaza Acequia Suite Black Plus
3.5 star property
Cuautitlán Izcalli
10.0 out of 10, Exceptional, (1 review)
"Todo un ambiente acogedor"
Mexico
GENER KEINER
The price is £72
includes taxes & fees
7 Nov - 8 Nov
A30 Plaza Acequia Suite Black Plus
A spacious lounge area with wooden flooring, several chairs, and tables. A reception desk is visible in the background.

2. A21 Full Suite MiniDept at Plaza Acequia

A21 Full Suite MiniDept at Plaza Acequia
3.5 star property
Cuautitlan Izcalli
10.0 out of 10, Exceptional, (1 review)
The price is £64
includes taxes & fees
11 Nov - 12 Nov
A21 Full Suite MiniDept at Plaza Acequia
A balcony with two chairs, a small table with a book and a cup, and a view of the cityscape.

3. S06 PREMIUM SUITE Full Service WiFi Kitc

S06 PREMIUM SUITE Full Service WiFi Kitc
3.5 star property
Ciudad López Mateos
9.8 out of 10, Exceptional, (6 reviews)
"Estuvo super bien nuestra estancia "
Mexico
Sophie
The price is £60
includes taxes & fees
6 Nov - 7 Nov
S06 PREMIUM SUITE Full Service WiFi Kitc
A spacious lounge area with wooden flooring, several chairs, and tables. A reception desk is visible in the background.

4. A08 SUPER CITY SUITES AT PLAZA ACEQUIA

A08 SUPER CITY SUITES AT PLAZA ACEQUIA
3.5 star property
Cuautitlan Izcalli
8.4 out of 10, Very good, (5 reviews)
"Muy buena atención y servicio un poco raro pero bueno todo bueno y excelente en cuanto a comodidad me gustó 10 de 10 lo volverá a visitar."
Mexico
Gilberto
The price is £64
includes taxes & fees
15 Nov - 16 Nov
A08 SUPER CITY SUITES AT PLAZA ACEQUIA
Living area

5. Lofts by Verticca San Francisco

Lofts by Verticca San Francisco
3.5 star property
Ojo de Agua
8.6 out of 10, Excellent, (46 reviews)
"Nice place! "
Canada
erick
The price is £47
includes taxes & fees
7 Nov - 8 Nov
Lofts by Verticca San Francisco
A hotel entrance with a glass door and a sign displaying greetings in multiple languages.

6. A11 SUPER SUITE PREMIUM AT PLAZA ACEQUIA

A11 SUPER SUITE PREMIUM AT PLAZA ACEQUIA
3.5 star property
Cuautitlan Izcalli
The price is £77
includes taxes & fees
3 Dec - 4 Dec
A11 SUPER SUITE PREMIUM AT PLAZA ACEQUIA
A compact kitchen with a built-in microwave, a gas stove, and a dishwasher.

7. Moderna, Comoda Suite Palma en Tepotzotlán centro

Moderna, Comoda Suite Palma en Tepotzotlán centro
3.0 star property
Tepotzotlán
10.0 out of 10, Exceptional, (3 reviews)
"Friendly host who was very helpful in recommending things to do and places to eat. Located just a few blocks from the historical district. On your way there, you'll pass wonderful restaurants, coffee shops, gyms, and convient stores. This place is in a great location and having garage parking was a real plus. Absolutely a beautiful room and very clean. I was very impressed and highly recommend staying here."
United States
Nathan
The price is £56
includes taxes & fees
10 Nov - 11 Nov
Moderna, Comoda Suite Palma en Tepotzotlán centro
A modern hotel corridor with a glass wall displaying multilingual greetings, a staircase, and a clean, tiled floor.

8. A05 SUPER SUITE PREMIUM AT PLAZA ACEQUIA

A05 SUPER SUITE PREMIUM AT PLAZA ACEQUIA
3.0 star property
Cuautitlan Izcalli
10.0 out of 10, Exceptional, (2 reviews)
"Lo único que me disgusta es que no hay agua caliente )): Pero sin duda iré todos los 12 de cada mes "
Mexico
Jeik
The price is £64
includes taxes & fees
21 Nov - 22 Nov
A05 SUPER SUITE PREMIUM AT PLAZA ACEQUIA
A compact kitchen with a wooden cabinet, a sink, and a countertop. There are kitchen utensils and a coffee maker on the counter.

9. S02 FULL SUITE ITESM CEM WiFi Terraza

S02 FULL SUITE ITESM CEM WiFi Terraza
3.5 star property
Ciudad López Mateos
10.0 out of 10, Exceptional, (1 review)
"Muy limpio Agradable la señorita de limpieza"
Mexico
Mauricio
The price is £62
includes taxes & fees
6 Nov - 7 Nov
S02 FULL SUITE ITESM CEM WiFi Terraza
A modern hotel corridor with a glass wall displaying multilingual greetings, a staircase, and a clean, tiled floor.

10. A04 SUPER SUITE PREMIUM AT PLAZA ACEQUIA

A04 SUPER SUITE PREMIUM AT PLAZA ACEQUIA
3.0 star property
Cuautitlan Izcalli
9.4 out of 10, Exceptional, (3 reviews)
"Buenas instalaciones y ubicación para mis desplazamientos"
Mexico
ANGEL
The price is £64
includes taxes & fees
6 Nov - 7 Nov
A04 SUPER SUITE PREMIUM AT PLAZA ACEQUIA
A spacious lounge area with wooden flooring, several chairs, and tables. A reception desk is visible in the background.

11. A07 SUPER CITY SUITES AT PLAZA ACEQUIA

A07 SUPER CITY SUITES AT PLAZA ACEQUIA
3.0 star property
Cuautitlan Izcalli
10.0 out of 10, Exceptional, (2 reviews)
"Buen lugar tranquilo "
Mexico
Valeria
The price is £46
includes taxes & fees
3 Dec - 4 Dec
A07 SUPER CITY SUITES AT PLAZA ACEQUIA
Balcony

12. S09 PREMIUM SUITE Full Service WiFi

S09 PREMIUM SUITE Full Service WiFi
3.5 star property
Ciudad López Mateos
9.6 out of 10, Exceptional, (4 reviews)
"Excelente"
United States
Yulissa Rubi
The price is £60
includes taxes & fees
6 Nov - 7 Nov
S09 PREMIUM SUITE Full Service WiFi
A compact kitchen with a built-in microwave, a coffee maker, and a sink. A flat-screen TV is mounted on the wall, displaying a menu interface.

13. A01 SUPER SUITE PREMIUM AT PLAZA ACEQUIA

A01 SUPER SUITE PREMIUM AT PLAZA ACEQUIA
3.5 star property
Cuautitlan Izcalli
The price is £59
includes taxes & fees
3 Dec - 4 Dec
A01 SUPER SUITE PREMIUM AT PLAZA ACEQUIA
A courtyard with a checkered floor, a covered seating area with a railing, and potted plants.

14. Casa Chopo

Casa Chopo
3.5 star property
Cuauhtémoc
9.4 out of 10, Exceptional, (158 reviews)
"very friendly staffs"
United States
Pengfei
The price is £37
includes taxes & fees
11 Nov - 12 Nov
Casa Chopo
A spacious lounge area with wooden flooring, several chairs, and tables. A reception desk is visible in the background.

15. A25 Full Suite MiniDept at Plaza Acequia

A25 Full Suite MiniDept at Plaza Acequia
3.0 star property
Cuautitlan Izcalli
10.0 out of 10, Exceptional, (1 review)
The price is £74
includes taxes & fees
3 Dec - 4 Dec
A25 Full Suite MiniDept at Plaza Acequia
A palm tree in front of a building with arched windows and a brick facade.

16. cabañas en arcos del sitio

cabañas en arcos del sitio
3.0 star property
Nicolás Romero
The price is £128
includes taxes & fees
6 Nov - 7 Nov
cabañas en arcos del sitio
A spacious lounge area with wooden flooring, several chairs, and tables. A reception desk is visible in the background.

17. A02 SUPER SUITE PREMIUM AT PLAZA ACEQUIA

A02 SUPER SUITE PREMIUM AT PLAZA ACEQUIA
3.0 star property
Cuautitlan Izcalli
The price is £58
includes taxes & fees
3 Dec - 4 Dec
A02 SUPER SUITE PREMIUM AT PLAZA ACEQUIA
A modern hotel corridor with a glass wall displaying multilingual greetings, a staircase, and a clean, tiled floor.

18. A13 SUPER CITY SUITE PLAZA ACEQUIA

A13 SUPER CITY SUITE PLAZA ACEQUIA
3.5 star property
Cuautitlan Izcalli
10.0 out of 10, Exceptional, (1 review)
"Buen servicio "
Mexico
Ruben
The price is £63
includes taxes & fees
4 Dec - 5 Dec
A13 SUPER CITY SUITE PLAZA ACEQUIA
A balcony with a blue chair, a table with a book, a water bottle, and a potted plant.

19. S08 PREMIUM SUITE Full Service WiFi

S08 PREMIUM SUITE Full Service WiFi
3.5 star property
Ciudad López Mateos
The price is £57
includes taxes & fees
6 Nov - 7 Nov
S08 PREMIUM SUITE Full Service WiFi
A modern outdoor dining area with a table set for breakfast, surrounded by potted plants and a view of the building's interior.

20. ULIV Parque Lincoln

ULIV Parque Lincoln
3.5 star property
Polanco
9.6 out of 10, Exceptional, (1,287 reviews)
"Great space, great location, friendly staff"
United States
Manuel
The price is £143
includes taxes & fees
7 Nov - 8 Nov
ULIV Parque Lincoln
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Cruz Hotel Reviews

Collections by ULIV Polanco

Collections by ULIV Polanco

10/10 Excellent
"Security on ground floor provided peace of mind."
John 3-night trip
Posted 4 hours ago
Collections by ULIV Polanco

Find out more about Santa Cruz

Everything you need to know about Santa Cruz holiday rentals

Whether you’re excited for the perfect family holiday, a romantic getaway for two, or the ultimate city break, we’ve got the Santa Cruz holiday rental for you. At Expedia, you can take your pick from private holiday homes, apartments, cottages, apart-hotels, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santa Cruz holiday rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. 

Santa Cruz holiday rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santa Cruz. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in . 

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Santa Cruz holiday rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a holiday rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Santa Cruz holiday rentals we have selected for you start as low as £34 per night. Entering your travel dates in the search wizard you might find even better deals!

How to find incredible deals on Santa Cruz rentals

At Expedia, we put the best Santa Cruz holiday rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. 

To find some top Santa Cruz rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santa Cruz holiday.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santa Cruz. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. 

Frequently asked questions

Are there holiday rentals in Santa Cruz?

Yes, there are holiday rentals close to the most popular sights in Santa Cruz, or you can select a more secluded option if you're looking for a relaxing stay.

What are some of the best holiday rentals that Santa Cruz has to offer?

Luxe Polanco Home Private Yard and Private Patio: This holiday home rental outside of Santa Cruz offers a garden, a selection of games and laundry facilities to help you feel perfectly comfortable in your new surroundings. It has 7 bedrooms, as well as a kitchen with a fridge, a stovetop and a microwave, so that you can cook with friends or family.

What’s there to see and do in Santa Cruz?

Explore the area and family-friendly sights such as Parque Acuatico Vito Spa, or get out into nature at a spot like Hacienda La Concepcion. Temple of San Francisco Javier and National Museum of the Viceroyalty are a couple of places you'll find in the wider area.

What’s a holiday rental in Santa Cruz like?

Holiday rentals are private properties where you can stay for a few weeks, or just a few days, in Santa Cruz. Holiday rentals offer amenities such as laundry facilities and kitchens so you'll feel just like you're staying in your own home. If you're concerned about a sanitised environment, holiday rentals can provide a sense of privacy away from public hotel lifts and lobbies packed with people while still allowing you a great travel experience. You'll also have more space in a holiday rental than in a hotel, which is another reason why a holiday rental is a great choice for a family getaway.