Title: Santa Cruz Holiday Homes from £36: Search Holiday Homes in Santa Cruz | Expedia.co.uk [Santa Cruz Travel Guide](https://expedia.co.uk/Santa-Cruz.dx6053940)[Hotels in Santa Cruz](https://expedia.co.uk/Santa-Cruz-Hotels.d6053940.Travel-Guide-Hotels)[Holiday Rentals in Santa Cruz](https://expedia.co.uk/Santa-Cruz-Holiday-Rentals.d6053940.Travel-Guide-HolidayRentals)[Flights to Santa Cruz](https://expedia.co.uk/Cheap-Flights-To-Santa-Cruz.d6053940.Travel-Guide-Flights)[Santa Cruz Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santa-Cruz.d6053940.Car-Hire-Guide)[Santa Cruz Holidays](https://expedia.co.uk/Santa-Cruz.d6053940.Holidays-City-Breaks) ![San Lorenzo Cathedral showing a garden](https://images.trvl-media.com/place/6098830/62a42b3d-1dbd-4a81-8566-cea655ebca33.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6098830/62a42b3d-1dbd-4a81-8566-cea655ebca33.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates In two weeks [10 Apr - 12 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=6053940&startDate=2026-04-10&endDate=2026-04-12&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [22 May - 24 May](https://www.expedia.co.uk/Hotel-Search?regionId=6053940&startDate=2026-05-22&endDate=2026-05-24&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [19 Jun - 21 Jun](https://www.expedia.co.uk/Hotel-Search?regionId=6053940&startDate=2026-06-19&endDate=2026-06-21&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [17 Jul - 19 Jul](https://www.expedia.co.uk/Hotel-Search?regionId=6053940&startDate=2026-07-17&endDate=2026-07-19&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Santa Cruz holiday homes ![Dining](https://images.trvl-media.com/lodging/91000000/90330000/90324500/90324441/w689h954x0y0-7d2c5be0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, WiFi](https://images.trvl-media.com/lodging/91000000/90330000/90324500/90324441/0169c880.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/91000000/90330000/90324500/90324441/bde12cb9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/91000000/90330000/90324500/90324441/af1568a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy and independent.
Downtown house JH. [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Furnished-Independent-House.h90324441.Hotel-Information) Santa Cruz de la Sierra £41 30 Mar - 31 Mar [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Furnished-Independent-House.h90324441.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/92000000/91740000/91736500/91736481/31570fe8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/92000000/91740000/91736500/91736481/31bf5785.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/92000000/91740000/91736500/91736481/f1f8846e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Parking](https://images.trvl-media.com/lodging/92000000/91740000/91736500/91736481/573f8196.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quiet, cozy, . Ideal to rest without noise [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Quiet.h91736481.Hotel-Information) Santa Cruz de la Sierra £36 25 Mar - 26 Mar [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Quiet.h91736481.Hotel-Information) ![2 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/97000000/96060000/96051200/96051149/697a6a82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/97000000/96060000/96051200/96051149/ce114a9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/97000000/96060000/96051200/96051149/2ea0b66a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/97000000/96060000/96051200/96051149/98d2bf31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa independiente estilo rustico. Ideal para familias o grupo de amigos. [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Casa-Independiente-Estilo-Rustico-Ideal-Para-Familias-O-Grupo-De-Amigos.h96051149.Hotel-Information) Santa Cruz de la Sierra £89 31 Mar - 1 Apr [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Casa-Independiente-Estilo-Rustico-Ideal-Para-Familias-O-Grupo-De-Amigos.h96051149.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/38000000/37280000/37274400/37274338/08f6d684.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/38000000/37280000/37274400/37274338/dd66fd7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/38000000/37280000/37274400/37274338/3f855619.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, WiFi](https://images.trvl-media.com/lodging/38000000/37280000/37274400/37274338/dde3f130.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aguas Calientes a heavenly place [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Aguas-Calientes-A-Heavenly-Place.h37274338.Hotel-Information) Roboré £95 31 Mar - 1 Apr [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Aguas-Calientes-A-Heavenly-Place.h37274338.Hotel-Information) ![4 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/123000000/122660000/122658000/122657972/2420a39e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, dishwasher](https://images.trvl-media.com/lodging/123000000/122660000/122658000/122657972/12a4586d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/123000000/122660000/122658000/122657972/906b94e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/123000000/122660000/122658000/122657972/b029b407.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Exclusive Condominium Home - Resort Style Living with Pool and Parks 🌴🏊‍♂️ [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Vrbo-Property.h122657972.Hotel-Information) Santa Cruz de la Sierra £80 25 Mar - 26 Mar [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Vrbo-Property.h122657972.Hotel-Information) ![3 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/97000000/96310000/96309900/96309820/d4637da6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/97000000/96310000/96309900/96309820/e4508bcf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/97000000/96310000/96309900/96309820/d5982077.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/97000000/96310000/96309900/96309820/e2f3303f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Posada Express by Transit Inn Aeropuerto Viru Viru [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Posada-Express-By-Transit-Inn-Aeropuerto-Viru-Viru.h96309820.Hotel-Information) Santa Cruz de la Sierra £55 31 Mar - 1 Apr [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Posada-Express-By-Transit-Inn-Aeropuerto-Viru-Viru.h96309820.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-04-07&endDate=2026-04-08®ionId=6053940&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ## Find holiday rentals that suit your style Aparthotels [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Cruz%2C+Santa+Cruz%2C+Bolivia®ionId=6053940&latLong=-17.784489%2C-63.180824&adults=2&startDate=2026-06-22&d1=2026-06-22&endDate=2026-06-25&d2=2026-06-25&lodging=APART_HOTEL) Apartments [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Cruz%2C+Santa+Cruz%2C+Bolivia®ionId=6053940&latLong=-17.784489%2C-63.180824&adults=2&startDate=2026-06-22&d1=2026-06-22&endDate=2026-06-25&d2=2026-06-25&lodging=APARTMENT) Private holiday homes [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Cruz%2C+Santa+Cruz%2C+Bolivia®ionId=6053940&latLong=-17.784489%2C-63.180824&adults=2&startDate=2026-06-22&d1=2026-06-22&endDate=2026-06-25&d2=2026-06-25&lodging=VACATION_HOME) Condos [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Cruz%2C+Santa+Cruz%2C+Bolivia®ionId=6053940&latLong=-17.784489%2C-63.180824&adults=2&startDate=2026-06-22&d1=2026-06-22&endDate=2026-06-25&d2=2026-06-25&lodging=CONDO) Houseboats [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Cruz%2C+Santa+Cruz%2C+Bolivia®ionId=6053940&latLong=-17.784489%2C-63.180824&adults=2&startDate=2026-06-22&d1=2026-06-22&endDate=2026-06-25&d2=2026-06-25&lodging=HOUSE_BOAT) Cottages [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Cruz%2C+Santa+Cruz%2C+Bolivia®ionId=6053940&latLong=-17.784489%2C-63.180824&adults=2&startDate=2026-06-22&d1=2026-06-22&endDate=2026-06-25&d2=2026-06-25&lodging=COTTAGE) Chalets [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Cruz%2C+Santa+Cruz%2C+Bolivia®ionId=6053940&latLong=-17.784489%2C-63.180824&adults=2&startDate=2026-06-22&d1=2026-06-22&endDate=2026-06-25&d2=2026-06-25&lodging=CHALET) Cabins [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Cruz%2C+Santa+Cruz%2C+Bolivia®ionId=6053940&latLong=-17.784489%2C-63.180824&adults=2&startDate=2026-06-22&d1=2026-06-22&endDate=2026-06-25&d2=2026-06-25&lodging=CABIN) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Cruz-Private-Holiday-Homes.d6053940-aaPrivateHolidayHomes.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Cruz-Private-Holiday-Homes.d6053940-aaPrivateHolidayHomes.Travel-Guide-Accommodation) ## Top Santa Cruz Hotel Reviews ![Premium Suites Deluxe Aparthotel Equipetrol](https://images.trvl-media.com/lodging/25000000/24410000/24404300/24404225/b86b5103_y.jpg) ### Premium Suites Deluxe Aparthotel Equipetrol 10/10 Excellent "The location was very good, close to several restaurants within walking distance." [](https://expedia.co.uk/Santa-Cruz-Hotels-Premium-Suites-Deluxe-Aparthotel-Equipetrol.h24404225.Hotel-Information) ![Camino Real Hotel](https://images.trvl-media.com/lodging/1000000/450000/444500/444475/9d61826a_y.jpg) ### Camino Real Hotel 10/10 Excellent "Good property the great amenities and service" [](https://expedia.co.uk/Santa-Cruz-Hotels-Camino-Real-Hotel.h444475.Hotel-Information) ![TRYP by Wyndham Santa Cruz](https://images.trvl-media.com/lodging/46000000/45620000/45617400/45617372/efaab5ae_y.jpg) ### TRYP by Wyndham Santa Cruz 10/10 Excellent "My go too hotel whenever I'm in town! " [](https://expedia.co.uk/Santa-Cruz-Hotels-TRYP-By-Wyndham-Santa-Cruz.h45617372.Hotel-Information) ![Sun Hotel](https://images.trvl-media.com/lodging/13000000/12840000/12836300/12836211/c21617f6_y.jpg) ### Sun Hotel 10/10 Excellent "Very close to the airport Room is so quiet and comfortable " [](https://expedia.co.uk/Santa-Cruz-Hotels-Sun-Hotel.h12836211.Hotel-Information) ![Hampton by Hilton Santa Cruz/Equipetrol, Bolivia](https://images.trvl-media.com/lodging/14000000/13180000/13179500/13179436/65fab765_y.jpg) ### Hampton by Hilton Santa Cruz/Equipetrol, Bolivia 10/10 Excellent "Super Clean Hotel. The Bathroom looks like a Sauna with a Central Súper Shower. The Bed has a Cloud feeling. Delicious Súper Breakfast. Highly recommended!" [](https://expedia.co.uk/Santa-Cruz-Hotels-Hampton-By-Hilton-Santa-Cruz.h13179436.Hotel-Information) ![Ibis Santa Cruz DE LA Sierra](https://images.trvl-media.com/lodging/88000000/87140000/87138700/87138613/03d4f9ed_y.jpg) ### Ibis Santa Cruz DE LA Sierra 10/10 Excellent "Good " [](https://expedia.co.uk/Santa-Cruz-Hotels-Ibis-Santa-Cruz-DE-LA-Sierra.h87138613.Hotel-Information) ![Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel](https://images.trvl-media.com/lodging/1000000/20000/18800/18758/ce43592e_y.jpg) ### Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel 10/10 Excellent "Yes" [](https://expedia.co.uk/Santa-Cruz-Hotels-Los-Tajibos-Hotel-And-Convention-Center.h18758.Hotel-Information) ![Novotel Santa Cruz De La Sierra](https://images.trvl-media.com/lodging/70000000/69570000/69566300/69566260/efe5b8af_y.jpg) ### Novotel Santa Cruz De La Sierra 10/10 Excellent "Quarto, restaurant, equipe" [](https://expedia.co.uk/Santa-Cruz-Hotels-Novotel-Santa-Cruz-De-La-Sierra.h69566260.Hotel-Information) ![Marriott Santa Cruz de la Sierra Hotel](https://images.trvl-media.com/lodging/22000000/21500000/21490300/21490226/02f3d22f_y.jpg) ### Marriott Santa Cruz de la Sierra Hotel 6/10 Okay "Mattress was hard, pillows flattened, no microwave and fridge was not cooling. Other than that, the personnel were 5 stars, friendly attentive and respectful. " [](https://expedia.co.uk/Santa-Cruz-Hotels-Marriott-Santa-Cruz-De-La-Sierra-Hotel.h21490226.Hotel-Information) ## Find out more about Santa Cruz ## Santa Cruz Holiday Homes information | Number of reviews | | | ----------------- | ---------------- | | Accommodation | 19 Holiday Homes | | Lowest Price | £36 | | Highest Price | £95 |