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Check prices for these dates

Next weekend
20 Nov - 22 Nov
In two weeks
27 Nov - 29 Nov
In one month
11 Dec - 13 Dec
In two months
8 Jan - 10 Jan

Our top choices for Santa Cruz holiday homes

A dining area with a table set for four, a pitcher, cups, and saucers on a white tablecloth.

1. Comfortable and independent.<br>House in downtown JH.

Comfortable and independent.<br>House in downtown JH.
Santa Cruz de la Sierra
The price is £34
11 Nov - 12 Nov
Comfortable and independent.<br>House in downtown JH.
A dining area with a rectangular table and six chairs with cut-out backrests.

2. A cozy home, far from the noise of the city.

A cozy home, far from the noise of the city.
Santa Cruz de la Sierra
The price is £26
11 Nov - 12 Nov
A cozy home, far from the noise of the city.
A swimming pool with a waterfall feature, surrounded by lush greenery and palm trees.

3. Casa Vida

Casa Vida
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (2 reviews)
"buena recepción, el lugar es muy bueno un poco alejado de la ciudad, falta comodidad en algunos aspectos pero la casa es grande y espaciosa"
Chile
FERNANDO
The price is £59
10 Dec - 11 Dec
Casa Vida
A modern bedroom with a large bed, a small bedside table, a decorative rug, and a painting on the wall.

4. Exclusive Condo Building - Resort-Style Living with a Pool and Parks 🌴🏊‍♂️

Exclusive Condo Building - Resort-Style Living with a Pool and Parks 🌴🏊‍♂️
Santa Cruz de la Sierra
The price is £72
11 Nov - 12 Nov
Exclusive Condo Building - Resort-Style Living with a Pool and Parks 🌴🏊‍♂️
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Santa Cruz

Tropical energy pulses through Plaza 24 de Septiembre, where locals gather under palm trees and the Metropolitan Cathedral's twin towers stand watch. Biocentro Güembé offers rainforest trails with butterfly gardens, while the massive Ventura Mall provides air-conditioned shopping when afternoon temperatures climb.

See all hotels in Santa Cruz
A historic cathedral with two prominent towers, surrounded by urban buildings and palm trees.