Title: Santa Cruz Holiday Homes from £36: Search Holiday Homes in Santa Cruz | Expedia.co.uk [Santa Cruz Travel Guide](https://expedia.co.uk/Santa-Cruz.dx6053940)[Hotels in Santa Cruz](https://expedia.co.uk/Santa-Cruz-Hotels.d6053940.Travel-Guide-Hotels)[Holiday Rentals in Santa Cruz](https://expedia.co.uk/Santa-Cruz-Holiday-Rentals.d6053940.Travel-Guide-HolidayRentals)[Flights to Santa Cruz](https://expedia.co.uk/Cheap-Flights-To-Santa-Cruz.d6053940.Travel-Guide-Flights)[Santa Cruz Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santa-Cruz.d6053940.Car-Hire-Guide)[Santa Cruz Holidays](https://expedia.co.uk/Santa-Cruz.d6053940.Holidays-City-Breaks) ![San Lorenzo Cathedral showing a garden](https://images.trvl-media.com/place/6098830/62a42b3d-1dbd-4a81-8566-cea655ebca33.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6098830/62a42b3d-1dbd-4a81-8566-cea655ebca33.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates In two weeks [20 Feb - 22 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=6053940&startDate=2026-02-20&endDate=2026-02-22&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [3 Apr - 5 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=6053940&startDate=2026-04-03&endDate=2026-04-05&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [1 May - 3 May](https://www.expedia.co.uk/Hotel-Search?regionId=6053940&startDate=2026-05-01&endDate=2026-05-03&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [29 May - 31 May](https://www.expedia.co.uk/Hotel-Search?regionId=6053940&startDate=2026-05-29&endDate=2026-05-31&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Santa Cruz holiday homes ![Dining](https://images.trvl-media.com/lodging/91000000/90330000/90324500/90324441/w689h954x0y0-7d2c5be0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, oven, dishwasher, electric kettle](https://images.trvl-media.com/lodging/91000000/90330000/90324500/90324441/7272b045.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/91000000/90330000/90324500/90324441/bde12cb9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, WiFi](https://images.trvl-media.com/lodging/91000000/90330000/90324500/90324441/0169c880.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy and independent.
Downtown house JH. [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Furnished-Independent-House.h90324441.Hotel-Information) Santa Cruz de la Sierra £41 18 Feb - 19 Feb [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Furnished-Independent-House.h90324441.Hotel-Information) ![2 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/97000000/96060000/96051200/96051149/697a6a82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/97000000/96060000/96051200/96051149/ce114a9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/97000000/96060000/96051200/96051149/98d2bf31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/97000000/96060000/96051200/96051149/bc40ca68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casa independiente estilo rustico. Ideal para familias o grupo de amigos. [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Casa-Independiente-Estilo-Rustico-Ideal-Para-Familias-O-Grupo-De-Amigos.h96051149.Hotel-Information) Santa Cruz de la Sierra £88 7 Feb - 8 Feb [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Casa-Independiente-Estilo-Rustico-Ideal-Para-Familias-O-Grupo-De-Amigos.h96051149.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/92000000/91740000/91736500/91736481/31570fe8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/92000000/91740000/91736500/91736481/f1f8846e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/92000000/91740000/91736500/91736481/bda7c717.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/92000000/91740000/91736500/91736481/31bf5785.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quiet, cozy, . Ideal to rest without noise [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Quiet.h91736481.Hotel-Information) Santa Cruz de la Sierra £36 7 Feb - 8 Feb [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Quiet.h91736481.Hotel-Information) ![4 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/123000000/122660000/122658000/122657972/2420a39e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/123000000/122660000/122658000/122657972/b029b407.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/123000000/122660000/122658000/122657972/199af1f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, dishwasher](https://images.trvl-media.com/lodging/123000000/122660000/122658000/122657972/12a4586d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Exclusive Condominium Home - Resort Style Living with Pool and Parks 🌴🏊‍♂️ [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Vrbo-Property.h122657972.Hotel-Information) Santa Cruz de la Sierra £78 18 Feb - 19 Feb [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Vrbo-Property.h122657972.Hotel-Information) ![3 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/97000000/96310000/96309900/96309820/d4637da6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/97000000/96310000/96309900/96309820/e4508bcf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/97000000/96310000/96309900/96309820/d5982077.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/97000000/96310000/96309900/96309820/e2f3303f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Posada Express by Transit Inn Aeropuerto Viru Viru [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Posada-Express-By-Transit-Inn-Aeropuerto-Viru-Viru.h96309820.Hotel-Information) Santa Cruz de la Sierra £54 18 Feb - 19 Feb [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Posada-Express-By-Transit-Inn-Aeropuerto-Viru-Viru.h96309820.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/38000000/37280000/37274400/37274338/08f6d684.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/38000000/37280000/37274400/37274338/c0c2c19a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/38000000/37280000/37274400/37274338/dd66fd7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/38000000/37280000/37274400/37274338/3f855619.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aguas Calientes a heavenly place [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Aguas-Calientes-A-Heavenly-Place.h37274338.Hotel-Information) Roboré £94 7 Feb - 8 Feb [](https://www.expedia.co.uk/Santa-Cruz-Hotels-Aguas-Calientes-A-Heavenly-Place.h37274338.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-02-20&endDate=2026-02-09®ionId=6053940&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ## Find holiday rentals that suit your style Apartments [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Cruz%2C+Santa+Cruz%2C+Bolivia®ionId=6053940&latLong=-17.784489%2C-63.180824&adults=2&startDate=2026-05-07&d1=2026-05-07&endDate=2026-05-10&d2=2026-05-10&lodging=APARTMENT) Aparthotels [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Cruz%2C+Santa+Cruz%2C+Bolivia®ionId=6053940&latLong=-17.784489%2C-63.180824&adults=2&startDate=2026-05-07&d1=2026-05-07&endDate=2026-05-10&d2=2026-05-10&lodging=APART_HOTEL) Private holiday homes [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Cruz%2C+Santa+Cruz%2C+Bolivia®ionId=6053940&latLong=-17.784489%2C-63.180824&adults=2&startDate=2026-05-07&d1=2026-05-07&endDate=2026-05-10&d2=2026-05-10&lodging=VACATION_HOME) Condos [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Cruz%2C+Santa+Cruz%2C+Bolivia®ionId=6053940&latLong=-17.784489%2C-63.180824&adults=2&startDate=2026-05-07&d1=2026-05-07&endDate=2026-05-10&d2=2026-05-10&lodging=CONDO) Houseboats [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Cruz%2C+Santa+Cruz%2C+Bolivia®ionId=6053940&latLong=-17.784489%2C-63.180824&adults=2&startDate=2026-05-07&d1=2026-05-07&endDate=2026-05-10&d2=2026-05-10&lodging=HOUSE_BOAT) Chalets [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Cruz%2C+Santa+Cruz%2C+Bolivia®ionId=6053940&latLong=-17.784489%2C-63.180824&adults=2&startDate=2026-05-07&d1=2026-05-07&endDate=2026-05-10&d2=2026-05-10&lodging=CHALET) Cottages [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Cruz%2C+Santa+Cruz%2C+Bolivia®ionId=6053940&latLong=-17.784489%2C-63.180824&adults=2&startDate=2026-05-07&d1=2026-05-07&endDate=2026-05-10&d2=2026-05-10&lodging=COTTAGE) Cabins [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Cruz%2C+Santa+Cruz%2C+Bolivia®ionId=6053940&latLong=-17.784489%2C-63.180824&adults=2&startDate=2026-05-07&d1=2026-05-07&endDate=2026-05-10&d2=2026-05-10&lodging=CABIN) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Cruz-Private-Holiday-Homes.d6053940-aaPrivateHolidayHomes.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Cruz-Private-Holiday-Homes.d6053940-aaPrivateHolidayHomes.Travel-Guide-Accommodation) ## Top Santa Cruz Hotel Reviews ![Sun Hotel](https://images.trvl-media.com/lodging/13000000/12840000/12836300/12836211/d021f216_y.jpg) ### Sun Hotel 10/10 Excellent "Awesome place " [](https://expedia.co.uk/Santa-Cruz-Hotels-Sun-Hotel.h12836211.Hotel-Information) ![Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel](https://images.trvl-media.com/lodging/1000000/20000/18800/18758/bb34bb1f_y.jpg) ### Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel 10/10 Excellent "Welcoming clean rooms, friendly staff, continental breakfast with natural drinks " [](https://expedia.co.uk/Santa-Cruz-Hotels-Los-Tajibos-Hotel-And-Convention-Center.h18758.Hotel-Information) ![HOTEL OSHO](https://images.trvl-media.com/lodging/76000000/75260000/75254900/75254801/286f65b1_y.jpg) ### HOTEL OSHO 10/10 Excellent "Room was great and staff were very accommodating!" [](https://expedia.co.uk/Santa-Cruz-Hotels-HOTEL-OSHO.h75254801.Hotel-Information) ![Camino Real Hotel](https://images.trvl-media.com/lodging/1000000/450000/444500/444475/e96a8418_y.jpg) ### Camino Real Hotel 10/10 Excellent "Rooms were very clean and service was excellent " [](https://expedia.co.uk/Santa-Cruz-Hotels-Camino-Real-Hotel.h444475.Hotel-Information) ![TRYP by Wyndham Santa Cruz](https://images.trvl-media.com/lodging/46000000/45620000/45617400/45617372/78f237b9_y.jpg) ### TRYP by Wyndham Santa Cruz 10/10 Excellent "Yes! Room was spotless. The staff are very patient and professional. " [](https://expedia.co.uk/Santa-Cruz-Hotels-TRYP-By-Wyndham-Santa-Cruz.h45617372.Hotel-Information) ![Lido Hotel](https://images.trvl-media.com/lodging/99000000/98240000/98237600/98237549/da03536f_y.jpg) ### Lido Hotel 10/10 Excellent "We stayed at the fabulous Lido Hotel for 2 nights in December 2025\. The hotel is located in central Santa Cruz, within a 4 block walk from Plaza 24 de Septiembre, and also a short 10 minute walk from the iconic Cristo Redentor statue. Check in was quick and painless, and the front desk staff was friendly and helpful. The room itself was spacious, clean and comfortable, with a large attached full bathroom. The air conditioner did a great job of cooling the room. Breakfast was served each morning in the attached Chinese restaurant, and featured eggs, breakfast meats, fruits, juices, cereal and yogurt, and was a great way to fuel up before venturing out to explore Santa Cruz. Without equivocation, I highly recommend the Lido Hotel to anyone in search of a clean comfortable hotel at an affordable price in the enchanting metrolopolis of Santa Cruz de la Sierra, Bolivia. Dr. Kingstone Shih and Laura Meneses Los Altos, California USA " [](https://expedia.co.uk/Santa-Cruz-Hotels-Hotel-Lido.h98237549.Hotel-Information) ![Ibis Santa Cruz DE LA Sierra](https://images.trvl-media.com/lodging/88000000/87140000/87138700/87138613/53c67151_y.jpg) ### Ibis Santa Cruz DE LA Sierra 10/10 Excellent "Amazing breakfast " [](https://expedia.co.uk/Santa-Cruz-Hotels-Ibis-Santa-Cruz-DE-LA-Sierra.h87138613.Hotel-Information) ![Hampton by Hilton Santa Cruz/Equipetrol, Bolivia](https://images.trvl-media.com/lodging/14000000/13180000/13179500/13179436/65fab765_y.jpg) ### Hampton by Hilton Santa Cruz/Equipetrol, Bolivia 10/10 Excellent "Maria in front desk was extremely helpful . Especially since we did not know the language and we checked in too late. She was kidn to arrange a taxi for us to get some fruits for dinner from supermarket. Maria is extremely responsive and was supportive throughout my entire stay. Thank you maria" [](https://expedia.co.uk/Santa-Cruz-Hotels-Hampton-By-Hilton-Santa-Cruz.h13179436.Hotel-Information) ![Chairú Eco Hotel](https://images.trvl-media.com/lodging/83000000/82390000/82389700/82389693/a88a9ace_y.jpg) ### Chairú Eco Hotel 10/10 Excellent "Clean room and friendly staff " [](https://expedia.co.uk/Santa-Cruz-Hotels-Chairu-Eco-Hotel.h82389693.Hotel-Information) ## Find out more about Santa Cruz ## Santa Cruz Holiday Homes information | Number of reviews | | | ----------------- | ---------------- | | Accommodation | 19 Holiday Homes | | Lowest Price | £36 | | Highest Price | £94 |