Title: Hotels in Santa Cruz - Best Santa Cruz Hotels from £70 - Fully Refundable Options - Expedia.co.uk [Holiday Rentals in Santa Cruz](https://expedia.co.uk/Santa-Cruz-Holiday-Rentals.d553248635640644100.Travel-Guide-HolidayRentals)[Santa Cruz Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santa-Cruz.d553248635640644100.Car-Hire-Guide)[Santa Cruz Holidays](https://expedia.co.uk/Santa-Cruz.d553248635640644100.Holidays-City-Breaks) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Santa Cruz Apart­ment [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Cruz%2C+Sonora%2C+Mexico®ionId=553248635640644100&latLong=31.192237%2C-110.54882&adults=2&startDate=2026-02-21&d1=2026-02-21&endDate=2026-02-23&d2=2026-02-23&lodging=APARTMENT) ## Check prices for these dates Tonight [7 Feb - 8 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=553248635640644100&startDate=2026-02-07&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [8 Feb - 9 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=553248635640644100&startDate=2026-02-08&endDate=2026-02-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [13 Feb - 15 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=553248635640644100&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [20 Feb - 22 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=553248635640644100&startDate=2026-02-20&endDate=2026-02-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Santa Cruz hotels ![Junior Room | Premium bedding, down duvets, Tempur-Pedic beds, individually decorated](https://images.trvl-media.com/lodging/86000000/85780000/85771400/85771365/6e0dd619.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/86000000/85780000/85771400/85771365/2702d4cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/86000000/85780000/85771400/85771365/5d47c29c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Room | Premium bedding, down duvets, Tempur-Pedic beds, individually decorated](https://images.trvl-media.com/lodging/86000000/85780000/85771400/85771365/2357a47d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Pedregal [](https://www.expedia.co.uk/Nogales-Hotels-Hotel-Pedregal.h85771365.Hotel-Information) Nogales 8.2/10 Very good (52 reviews) - Modern Nogales hotel 5 minutes from US Consulate with free WiFi and conference space. "Friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cinthya £70 includes taxes & fees 8 Feb - 9 Feb [](https://www.expedia.co.uk/Nogales-Hotels-Hotel-Pedregal.h85771365.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/8000000/7800000/7791000/7790964/752752a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/8000000/7800000/7791000/7790964/e9c25283.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Food court](https://images.trvl-media.com/lodging/8000000/7800000/7791000/7790964/581e16b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property – evening/night](https://images.trvl-media.com/lodging/8000000/7800000/7791000/7790964/380210c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Fray Marcos [](https://www.expedia.co.uk/Nogales-Hotels-Hotel-Fray-Marcos-De-Niza.h7790964.Hotel-Information) Nogales 7.8/10 Good (426 reviews) - Comfortable Nogales hotel offers international dining and free valet parking. "Room was very clean and just right for the night! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marco £80 includes taxes & fees 8 Feb - 9 Feb [](https://www.expedia.co.uk/Nogales-Hotels-Hotel-Fray-Marcos-De-Niza.h7790964.Hotel-Information) ![Front of property – evening/night](https://images.trvl-media.com/lodging/11000000/10260000/10253600/10253558/35f277b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/11000000/10260000/10253600/10253558/71277b70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/11000000/10260000/10253600/10253558/a0275688.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Room, 1 King Bed | Coffee and/or coffee maker](https://images.trvl-media.com/lodging/11000000/10260000/10253600/10253558/caca052a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Marques De Cima [](https://www.expedia.co.uk/Nogales-Hotels-Hotel-Marques-De-Cima.h10253558.Hotel-Information) Nogales 8.6/10 Excellent (866 reviews) - Discover a convenient Nogales hotel with free parking and helpful staff nearby. "Great place " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ricardo £81 includes taxes & fees 21 Feb - 22 Feb [](https://www.expedia.co.uk/Nogales-Hotels-Hotel-Marques-De-Cima.h10253558.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1150000/1145700/1145669/2f093d92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1150000/1145700/1145669/05aa6759.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1150000/1145700/1145669/2de7d1e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily buffet breakfast (MXN 289 per person)](https://images.trvl-media.com/lodging/2000000/1150000/1145700/1145669/e0e7e78f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fiesta Inn Nogales [](https://www.expedia.co.uk/Nogales-Hotels-Fiesta-Inn-Nogales.h1145669.Hotel-Information) Nueva Nogales 8.2/10 Very good (1,002 reviews) - Modern business hotel near Nogales Mall with outdoor pool and cafe dining. "Needs a turnover, carpet, painting, and better cleaning, smelled a bit bad." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Etianne £85 includes taxes & fees 6 Mar - 7 Mar [](https://www.expedia.co.uk/Nogales-Hotels-Fiesta-Inn-Nogales.h1145669.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/17000000/16260000/16255000/16254962/5f2606d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/17000000/16260000/16255000/16254962/7aab6239.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/17000000/16260000/16255000/16254962/c3edd730.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/17000000/16260000/16255000/16254962/68c8daf4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Nogales [](https://www.expedia.co.uk/Nogales-Hotels-Fairfield-Inn-Suites-By-Marriott-Nogales.h16254962.Hotel-Information) Nogales 8.4/10 Very good (1,001 reviews) - Cosy hotel near Nogales Mall with complimentary parking and daily buffet. "Clean room, great staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jose Manuel £97 includes taxes & fees 14 Feb - 15 Feb [](https://www.expedia.co.uk/Nogales-Hotels-Fairfield-Inn-Suites-By-Marriott-Nogales.h16254962.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/5000000/4330000/4326700/4326618/d58a431d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/5000000/4330000/4326700/4326618/c49cc055.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/5000000/4330000/4326700/4326618/a12f67e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4330000/4326700/4326618/w4000h2662x0y0-ffe7a275.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### City Express by Marriott Nogales [](https://www.expedia.co.uk/Nogales-Hotels-City-Express-Nogales.h4326618.Hotel-Information) Nogales 8.4/10 Very good (1,011 reviews) - Enjoy a prime location in Nogales, with free breakfast and parking for explorers. "Great Location, safe place, clean, good price " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Adolfo £80 includes taxes & fees 8 Mar - 9 Mar [](https://www.expedia.co.uk/Nogales-Hotels-City-Express-Nogales.h4326618.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/8000000/7120000/7111000/7110997/4283b02a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/8000000/7120000/7111000/7110997/w4000h2662x0y0-2f890369.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom | Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/8000000/7120000/7111000/7110997/3f93d17f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/8000000/7120000/7111000/7110997/7840c8f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### City Express by Marriott Cananea [](https://www.expedia.co.uk/Cananea-Hotels-City-Express-Cananea.h7110997.Hotel-Information) Cananea 9.0/10 Wonderful (357 reviews) - Relax at this modern Cananea hotel with free daily breakfast and on-site fitness. "Beautiful Location, excellent hotel." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Elsa £83 includes taxes & fees 8 Feb - 9 Feb [](https://www.expedia.co.uk/Cananea-Hotels-City-Express-Cananea.h7110997.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-02-21&endDate=2026-02-22®ionId=553248635640644100&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Cruz-Hotels.d553248635640644100.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Cruz-Hotels.d553248635640644100.Travel-Guide-Hotels) ## Top Santa Cruz Hotel Reviews ![City Express by Marriott Nogales](https://images.trvl-media.com/lodging/5000000/4330000/4326700/4326618/d58a431d_y.jpg) ### City Express by Marriott Nogales 10/10 Excellent "Very clean " [](https://expedia.co.uk/Nogales-Hotels-City-Express-Nogales.h4326618.Hotel-Information) ![Hotel Fray Marcos](https://images.trvl-media.com/lodging/8000000/7800000/7791000/7790964/cf07d2ea_y.jpg) ### Hotel Fray Marcos 10/10 Excellent "Very clean room! Excellent service! Definitely recommend if you’re looking " [](https://expedia.co.uk/Nogales-Hotels-Hotel-Fray-Marcos-De-Niza.h7790964.Hotel-Information) ![City Express by Marriott Cananea](https://images.trvl-media.com/lodging/8000000/7120000/7111000/7110997/877467b2_y.jpg) ### City Express by Marriott Cananea 10/10 Excellent "Comfortable " [](https://expedia.co.uk/Cananea-Hotels-City-Express-Cananea.h7110997.Hotel-Information) ![Charming 2-bedroom apartment with AC, WiFi in Heroica Nogales](https://images.trvl-media.com/lodging/111000000/110900000/110897000/110896941/w1288h963x1y4-3ed44adf_y.jpg) ### Charming 2-bedroom apartment with AC, WiFi in Heroica Nogales 8/10 Good "It was really nice. Very clean. Had some people staying in one of the other apartments that were kind of noisy on there way out early in the morning, but other than that it was a nice stay. I will definitely be going back." [](https://expedia.co.uk/Nogales-Hotels-Charming-2-Bedroom-Apartment-With-AC.h110896941.Hotel-Information) ## More cheap stays in Santa Cruz ![Hotel Pedregal](https://images.trvl-media.com/lodging/86000000/85780000/85771400/85771365/4df8605c_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Pedregal Av. del Yaqui Colinas del Yaqui Nogales Son. £70 8 Feb - 9 Feb includes taxes & fees 8.2/10 Very Good! (52 reviews) [](https://expedia.co.uk/Nogales-Hotels-Hotel-Pedregal.h85771365.Hotel-Information) ![Hotel Marques De Cima](https://images.trvl-media.com/lodging/11000000/10260000/10253600/10253558/cd117355_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Marques De Cima Av. Alvaro Obregon # 2024 Nogales SON £81 21 Feb - 22 Feb includes taxes & fees 8.4/10 Very Good! (865 reviews) [](https://expedia.co.uk/Nogales-Hotels-Hotel-Marques-De-Cima.h10253558.Hotel-Information) ![Studio 5 minutes from CAs and embassy](https://images.trvl-media.com/lodging/121000000/120880000/120876100/120876037/6cd5a3be_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Studio 5 minutes from CAs and embassy Heroica Nogales Son. £95 8 Feb - 9 Feb includes taxes & fees [](https://expedia.co.uk/Nogales-Hotels-Vrbo-Property.h120876037.Hotel-Information) ![Hotel Plaza Nogales](https://images.trvl-media.com/lodging/16000000/15370000/15362200/15362160/ce7fcac1_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Plaza Nogales Prolongacion Av.Alvaro Obregon 4190 Col. Nuevo Nogales Nogales SON [Get rates](https://expedia.co.uk/Hotel-Search?startDate=21%2F02%2F2026&endDate=22%2F02%2F2026&selected=15362160&PinnedHotelID=15362160&HadPinnedHotel=true®ionId=553248635640644100) [](https://expedia.co.uk/Nogales-Hotels-Hotel-Plaza-Nogales.h15362160.Hotel-Information) ## Frequently asked questions ### What is the best area to stay in Santa Cruz? > This area is the heart of Santa Cruz, offering a convenient base for exploring. You'll find many of the town's key landmarks, including the historic Templo de Nuestra Señora de Guadalupe, within easy walking distance. The streets here are generally well-maintained and offer a pleasant stroll amongst local shops and eateries. > > > Couples looking for a relaxed and authentic experience will find the town centre ideal. It provides opportunities to enjoy local cuisine, browse artisan crafts, and simply soak in the local way of life without needing to travel far. The evenings around Plaza Zaragoza often feature local gatherings, adding to the pleasant atmosphere. ### When is the best time to go to Santa Cruz? > During this period, the weather is pleasantly warm with average temperatures ranging from 20°C to 28°C, and there's very little rainfall. This makes it ideal for exploring the outdoors, whether you're interested in hiking the Sierra Azul mountains or enjoying the local markets without the intense heat of summer. > > > Couples looking for a relaxed getaway will appreciate the comfortable climate for leisurely strolls through the town's historic centre, perhaps visiting the Mission de Santa Cruz. The evenings are mild, superb for dining al fresco. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Santa Cruz hotel booking with Expedia? ### How much is the nightly rate at a Santa Cruz hotel? ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - More ways to book - [Agua Prieta Hotels ](https://www.expedia.co.uk/Agua-Prieta-Hotels.d6306196.Travel-Guide-Hotels) - [Altar Hotels ](https://www.expedia.co.uk/Altar-Hotels.d553248635612064094.Travel-Guide-Hotels) - [Arizpe Hotels ](https://www.expedia.co.uk/Arizpe-Hotels.d553248635640657566.Travel-Guide-Hotels) - [Banamichi Hotels ](https://www.expedia.co.uk/Banamichi-Hotels.d6125092.Travel-Guide-Hotels) - [Benjamín Hill Hotels ](https://www.expedia.co.uk/Benjamin-Hill-Hotels.d553248635640629488.Travel-Guide-Hotels) - [Imuris Hotels ](https://www.expedia.co.uk/Imuris-Hotels.d553248635640659701.Travel-Guide-Hotels) - [Magdalena de Kino Hotels ](https://www.expedia.co.uk/Magdalena-De-Kino-Hotels.d6346915.Travel-Guide-Hotels) - [Nogales Hotels ](https://www.expedia.co.uk/Nogales-Hotels.d6205.Travel-Guide-Hotels) - [Nueva Nogales Hotels ](https://www.expedia.co.uk/Nueva-Nogales-Nogales-Hotels.0-n553248635157665538-0.Travel-Guide-Filter-Hotels) - [Santa Ana Hotels ](https://www.expedia.co.uk/Santa-Ana-Hotels.d6346884.Travel-Guide-Hotels) - [Flights to Agua Prieta ](https://www.expedia.co.uk/Cheap-Flights-To-Agua-Prieta.d6306196.Travel-Guide-Flights) - [Flights to Altar ](https://www.expedia.co.uk/Cheap-Flights-To-Altar.d553248635612064094.Travel-Guide-Flights) - [Flights to Nogales ](https://www.expedia.co.uk/Cheap-Flights-To-Nogales.d6205.Travel-Guide-Flights) - [Agua Prieta Holidays ](https://www.expedia.co.uk/Agua-Prieta.d6306196.Holidays-City-Breaks) - [Altar Holidays ](https://www.expedia.co.uk/Altar.d553248635612064094.Holidays-City-Breaks) - [Visit Banamichi ](https://www.expedia.co.uk/Banamichi.dx6125092) - [Visit Magdalena de Kino ](https://www.expedia.co.uk/Magdalena-De-Kino.dx6346915) - [Nogales Holidays ](https://www.expedia.co.uk/Nogales.d6205.Holidays-City-Breaks) - [Car hire Agua Prieta ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Agua-Prieta.d6306196.Car-Hire-Guide) - [Book Hotels in Santa Cruz on Expedia.mx ](https://www.expedia.mx/Santa-Cruz-Hoteles.d553248635640644100.Guia-Viajes-Hoteles) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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