Title: Hotels in Santa Cruz - Best Santa Cruz Hotels from £58 - Fully Refundable Options - Expedia.co.uk [Holiday Rentals in Santa Cruz](https://expedia.co.uk/Santa-Cruz-Holiday-Rentals.d553248635640644100.Travel-Guide-HolidayRentals)[Santa Cruz Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santa-Cruz.d553248635640644100.Car-Hire-Guide)[Santa Cruz Holidays](https://expedia.co.uk/Santa-Cruz.d553248635640644100.Holidays-City-Breaks) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Santa Cruz from £58 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Santa Cruz Apart­ment [](https://www.expedia.co.uk/Hotel-Search?destination=Santa+Cruz%2C+Sonora%2C+Mexico®ionId=553248635640644100&latLong=31.192237%2C-110.54882&adults=2&startDate=2026-01-06&d1=2026-01-06&endDate=2026-01-08&d2=2026-01-08&lodging=APARTMENT) ## Check prices for these dates Tonight [23 Dec - 24 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248635640644100&startDate=2025-12-23&endDate=2025-12-24&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [24 Dec - 25 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248635640644100&startDate=2025-12-24&endDate=2025-12-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [26 Dec - 28 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248635640644100&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [2 Jan - 4 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=553248635640644100&startDate=2026-01-02&endDate=2026-01-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Santa Cruz hotels ![Lobby](https://images.trvl-media.com/lodging/8000000/7120000/7111000/7110997/4283b02a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom | Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/8000000/7120000/7111000/7110997/3f93d17f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/8000000/7120000/7111000/7110997/7840c8f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/8000000/7120000/7111000/7110997/w4000h2662x0y0-2f890369.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### City Express by Marriott Cananea [](https://www.expedia.co.uk/Cananea-Hotels-City-Express-Cananea.h7110997.Hotel-Information) Cananea 9.0/10 Wonderful (349) Located in Cananea near Alboa Lounge and Lanes Club, this contemporary hotel offers complimentary continental breakfast, WiFi, and parking. Work up a sweat in the fitness centre before exploring nearby Cinemex. --- "Beautiful Location, excellent hotel." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Elsa £64 includes taxes & fees 14 Jan - 15 Jan 2026 [](https://www.expedia.co.uk/Cananea-Hotels-City-Express-Cananea.h7110997.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/17000000/16260000/16255000/16254962/5f2606d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/17000000/16260000/16255000/16254962/c3edd730.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/17000000/16260000/16255000/16254962/30f2feca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/17000000/16260000/16255000/16254962/68c8daf4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Nogales [](https://www.expedia.co.uk/Nogales-Hotels-Fairfield-Inn-Suites-By-Marriott-Nogales.h16254962.Hotel-Information) Nogales 8.4/10 Very good (1000) Start your day with free breakfast at this business-friendly hotel near Nogales Mall and Galería Plaza Norte. After exploring local attractions, return to enjoy complimentary WiFi or squeeze in a workout at the fitness centre. --- "Good amenities " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jaime Guadalupe £105 includes taxes & fees 30 Dec - 31 Dec [](https://www.expedia.co.uk/Nogales-Hotels-Fairfield-Inn-Suites-By-Marriott-Nogales.h16254962.Hotel-Information) ![Front of property – evening/night](https://images.trvl-media.com/lodging/11000000/10260000/10253600/10253558/35f277b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/11000000/10260000/10253600/10253558/40415cf4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/11000000/10260000/10253600/10253558/71277b70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/11000000/10260000/10253600/10253558/a0275688.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Marques De Cima [](https://www.expedia.co.uk/Nogales-Hotels-Hotel-Marques-De-Cima.h10253558.Hotel-Information) Nogales 8.6/10 Excellent (849) This business-friendly Nogales hotel offers complimentary WiFi and parking, with a 24-hour front desk ensuring assistance anytime. Located near Nogales Mall and Galería Plaza Norte for shopping enthusiasts. --- "Great place " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ricardo £76 includes taxes & fees 27 Dec - 28 Dec [](https://www.expedia.co.uk/Nogales-Hotels-Hotel-Marques-De-Cima.h10253558.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/8000000/7800000/7791000/7790964/752752a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/8000000/7800000/7791000/7790964/e9c25283.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/8000000/7800000/7791000/7790964/32e45eb2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property – evening/night](https://images.trvl-media.com/lodging/8000000/7800000/7791000/7790964/380210c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Fray Marcos [](https://www.expedia.co.uk/Nogales-Hotels-Hotel-Fray-Marcos-De-Niza.h7790964.Hotel-Information) Nogales 7.8/10 Good (422) Experience convenience at this Nogales hotel with free WiFi and valet parking. The on-site Fray Mar restaurant serves international cuisine, while the bar provides relaxation. Explore Pimeria Alta Museum and Sacred Heart Parish nearby. --- "Very comfy, lots of places near hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brian £78 includes taxes & fees 25 Dec - 26 Dec [](https://www.expedia.co.uk/Nogales-Hotels-Hotel-Fray-Marcos-De-Niza.h7790964.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1150000/1145700/1145669/2f093d92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily buffet breakfast (MXN 289 per person)](https://images.trvl-media.com/lodging/2000000/1150000/1145700/1145669/e0e7e78f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/2000000/1150000/1145700/1145669/b67d9dcd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1150000/1145700/1145669/2de7d1e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fiesta Inn Nogales [](https://www.expedia.co.uk/Nogales-Hotels-Fiesta-Inn-Nogales.h1145669.Hotel-Information) Nueva Nogales 8.2/10 Very good (1000) Experience comfort at this Nogales hotel with an outdoor pool and 24-hour fitness centre. Cafe La Fiesta serves three daily meals, and the bar provides evening relaxation. Located near Nogales Mall and Galería Plaza Norte, with free WiFi and parking for added convenience. --- "I like the access to the main street and the privacy of the staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jose £80 includes taxes & fees 28 Dec - 29 Dec [](https://www.expedia.co.uk/Nogales-Hotels-Fiesta-Inn-Nogales.h1145669.Hotel-Information) ![Junior Room | Premium bedding, down duvets, Tempur-Pedic beds, individually decorated](https://images.trvl-media.com/lodging/86000000/85780000/85771400/85771365/6e0dd619.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/86000000/85780000/85771400/85771365/5d47c29c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/86000000/85780000/85771400/85771365/2702d4cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Room | Premium bedding, down duvets, Tempur-Pedic beds, individually decorated](https://images.trvl-media.com/lodging/86000000/85780000/85771400/85771365/2357a47d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Pedregal [](https://www.expedia.co.uk/Nogales-Hotels-Hotel-Pedregal.h85771365.Hotel-Information) Nogales 8.2/10 Very good (49) Positioned near United States Consulate, this comfortable hotel offers convenient access to Nogales Mall and Galería Plaza Norte. Enjoy complimentary WiFi while business travellers will appreciate the on-site conference centre. --- "Friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cinthya £68 includes taxes & fees 25 Dec - 26 Dec [](https://www.expedia.co.uk/Nogales-Hotels-Hotel-Pedregal.h85771365.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/5000000/4330000/4326700/4326618/d58a431d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/5000000/4330000/4326700/4326618/c49cc055.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/5000000/4330000/4326700/4326618/a12f67e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4330000/4326700/4326618/w4000h2662x0y0-ffe7a275.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### City Express by Marriott Nogales [](https://www.expedia.co.uk/Nogales-Hotels-City-Express-Nogales.h4326618.Hotel-Information) Nogales 8.2/10 Very good (1012) Conveniently positioned near Nogales Mall and Galería Plaza Norte, this hotel offers complimentary WiFi, daily buffet breakfast, and self parking. Energise in the fitness centre after a productive day exploring the area. Fellow travellers praise the attentive staff. --- "I love to staying here with my family." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) ROCIO £58 includes taxes & fees 28 Dec - 29 Dec [](https://www.expedia.co.uk/Nogales-Hotels-City-Express-Nogales.h4326618.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-07&endDate=2026-01-08®ionId=553248635640644100&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Cruz-Hotels.d553248635640644100.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Cruz-Hotels.d553248635640644100.Travel-Guide-Hotels) ## Top Santa Cruz Hotel Reviews ![Hotel Fray Marcos](https://images.trvl-media.com/lodging/8000000/7800000/7791000/7790964/cf07d2ea_y.jpg) ### Hotel Fray Marcos 10/10 Excellent "All very very good,excellent I loved " [](https://expedia.co.uk/Nogales-Hotels-Hotel-Fray-Marcos-De-Niza.h7790964.Hotel-Information) ![City Express by Marriott Cananea](https://images.trvl-media.com/lodging/8000000/7120000/7111000/7110997/877467b2_y.jpg) ### City Express by Marriott Cananea 10/10 Excellent "Excelente hospedaje. Caballero en recepcion amable y super servicial. Gran servicio." [](https://expedia.co.uk/Cananea-Hotels-City-Express-Cananea.h7110997.Hotel-Information) ![City Express by Marriott Nogales](https://images.trvl-media.com/lodging/5000000/4330000/4326700/4326618/d58a431d_y.jpg) ### City Express by Marriott Nogales 10/10 Excellent "Excellent. Looking forward to my next visit! " [](https://expedia.co.uk/Nogales-Hotels-City-Express-Nogales.h4326618.Hotel-Information) ![Charming 2-bedroom apartment with AC, WiFi in Heroica Nogales](https://images.trvl-media.com/lodging/111000000/110900000/110897000/110896941/w1288h963x1y4-3ed44adf_y.jpg) ### Charming 2-bedroom apartment with AC, WiFi in Heroica Nogales 8/10 Good "It was really nice. Very clean. Had some people staying in one of the other apartments that were kind of noisy on there way out early in the morning, but other than that it was a nice stay. I will definitely be going back." [](https://expedia.co.uk/Nogales-Hotels-Charming-2-Bedroom-Apartment-With-AC.h110896941.Hotel-Information) ## More cheap stays in Santa Cruz ![Hotel Pedregal](https://images.trvl-media.com/lodging/86000000/85780000/85771400/85771365/4df8605c_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Pedregal Av. del Yaqui Colinas del Yaqui Nogales Son. £68 25 Dec - 26 Dec includes taxes & fees 8/10 Very Good! (49 reviews) [](https://expedia.co.uk/Nogales-Hotels-Hotel-Pedregal.h85771365.Hotel-Information) ![Hotel Marques De Cima](https://images.trvl-media.com/lodging/11000000/10260000/10253600/10253558/cd117355_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Marques De Cima Av. Alvaro Obregon # 2024 Nogales SON £76 27 Dec - 28 Dec includes taxes & fees 8.4/10 Very Good! (843 reviews) [](https://expedia.co.uk/Nogales-Hotels-Hotel-Marques-De-Cima.h10253558.Hotel-Information) ![Studio 5 minutes from CAs and embassy](https://images.trvl-media.com/lodging/121000000/120880000/120876100/120876037/6cd5a3be_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Studio 5 minutes from CAs and embassy Heroica Nogales Son. £89 25 Dec - 26 Dec includes taxes & fees [](https://expedia.co.uk/Nogales-Hotels-Vrbo-Property.h120876037.Hotel-Information) ![Hotel Plaza Nogales](https://images.trvl-media.com/lodging/16000000/15370000/15362200/15362160/ce7fcac1_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Plaza Nogales Prolongacion Av.Alvaro Obregon 4190 Col. Nuevo Nogales Nogales SON [Get rates](https://expedia.co.uk/Hotel-Search?startDate=07%2F01%2F2026&endDate=08%2F01%2F2026&selected=15362160&PinnedHotelID=15362160&HadPinnedHotel=true®ionId=553248635640644100) [](https://expedia.co.uk/Nogales-Hotels-Hotel-Plaza-Nogales.h15362160.Hotel-Information) ## Frequently asked questions ### What's the best place to stay in Santa Cruz? ### What are some of the best holiday rentals that Santa Cruz has to offer? ### If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund? ### What's it like staying in Santa Cruz? ### What should I do while I'm visiting Santa Cruz? ### What's the weather like in Santa Cruz? ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - More ways to book - [Agua Prieta Hotels ](https://www.expedia.co.uk/Agua-Prieta-Hotels.d6306196.Travel-Guide-Hotels) - [Altar Hotels ](https://www.expedia.co.uk/Altar-Hotels.d553248635612064094.Travel-Guide-Hotels) - [Arizpe Hotels ](https://www.expedia.co.uk/Arizpe-Hotels.d553248635640657566.Travel-Guide-Hotels) - [Banamichi Hotels ](https://www.expedia.co.uk/Banamichi-Hotels.d6125092.Travel-Guide-Hotels) - [Benjamín Hill Hotels ](https://www.expedia.co.uk/Benjamin-Hill-Hotels.d553248635640629488.Travel-Guide-Hotels) - [Imuris Hotels ](https://www.expedia.co.uk/Imuris-Hotels.d553248635640659701.Travel-Guide-Hotels) - [Magdalena de Kino Hotels ](https://www.expedia.co.uk/Magdalena-De-Kino-Hotels.d6346915.Travel-Guide-Hotels) - [Nogales Hotels ](https://www.expedia.co.uk/Nogales-Hotels.d6205.Travel-Guide-Hotels) - [Nueva Nogales Hotels ](https://www.expedia.co.uk/Nueva-Nogales-Nogales-Hotels.0-n553248635157665538-0.Travel-Guide-Filter-Hotels) - [Santa Ana Hotels ](https://www.expedia.co.uk/Santa-Ana-Hotels.d6346884.Travel-Guide-Hotels) - [Flights to Agua Prieta ](https://www.expedia.co.uk/Cheap-Flights-To-Agua-Prieta.d6306196.Travel-Guide-Flights) - [Flights to Altar ](https://www.expedia.co.uk/Cheap-Flights-To-Altar.d553248635612064094.Travel-Guide-Flights) - [Flights to Nogales ](https://www.expedia.co.uk/Cheap-Flights-To-Nogales.d6205.Travel-Guide-Flights) - [Agua Prieta Holidays ](https://www.expedia.co.uk/Agua-Prieta.d6306196.Holidays-City-Breaks) - [Altar Holidays ](https://www.expedia.co.uk/Altar.d553248635612064094.Holidays-City-Breaks) - [Visit Banamichi ](https://www.expedia.co.uk/Banamichi.dx6125092) - [Visit Magdalena de Kino ](https://www.expedia.co.uk/Magdalena-De-Kino.dx6346915) - [Nogales Holidays ](https://www.expedia.co.uk/Nogales.d6205.Holidays-City-Breaks) - [Car hire Agua Prieta ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Agua-Prieta.d6306196.Car-Hire-Guide) - [Book Hotels in Santa Cruz on Expedia.mx ](https://www.expedia.mx/Santa-Cruz-Hoteles.d553248635640644100.Guia-Viajes-Hoteles) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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