Title: Santa Cruz Holidays 2026 from £301 | Expedia.co.uk [Hotels in Santa Cruz](https://expedia.co.uk/Santa-Cruz-Hotels.d553248635640644100.Travel-Guide-Hotels)[Holiday Rentals in Santa Cruz](https://expedia.co.uk/Santa-Cruz-Holiday-Rentals.d553248635640644100.Travel-Guide-HolidayRentals)[Santa Cruz Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Santa-Cruz.d553248635640644100.Car-Hire-Guide) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_packages.jpeg?impolicy=fcrop&w=1200&h=300&q=medium) # Santa Cruz Holidays from £301 ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to £335 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Packages with flights are ATOL protected ## Top Santa Cruz Flight + Hotel Deals Price found within the past 48 hours. Click for updated prices. ![Hotel Delle Civette](https://images.trvl-media.com/lodging/101000000/100970000/100969400/100969343/205f358e_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Delle Civette Nomentano £301 per person 16 May - 19 May found 1 day ago Return flight included Manchester (MAN) to Rome (FCO) 9.6/10 Exceptional! (288 reviews) All ok ok. Weird alarm on both nights- rooms are not soundproof. Room needed a rug- just too bare. Breakfast was good. It's not the most lively place. I did like that they had a kettle in the room. That was probably the nicest thing for me. Reviewed on 22 Mar 2026 ![Encore Inn Inglewood ](https://images.trvl-media.com/lodging/119000000/118100000/118098300/118098292/41a368f2_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Encore Inn Inglewood Lockhaven £704 per person 12 Jun - 17 Jun found 12 hours ago Return flight included London (LON) to Los Angeles (LAX) 6.4/10 (144 reviews) Clean room w/ a shower. Reviewed on 2 Jan 2026 ![Relais de la Poste](https://images.trvl-media.com/lodging/39000000/38910000/38902300/38902220/c47eaf80_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Relais de la Poste Rome City Centre £407 per person 14 May - 17 May found 1 day ago Return flight included London (LON) to Rome (FCO) 9.2/10 Wonderful! (641 reviews) Perfect Area and Very clean rooms Reviewed on 24 Mar 2026 ![APA Hotel Woodbridge](https://images.trvl-media.com/lodging/1000000/10000/7900/7883/f0e97905_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### APA Hotel Woodbridge £701 per person 13 May - 16 May found 6 hours ago Return flight included London (LHR) to Newark Liberty Intl. Airport (EWR) 8.4/10 Very Good! (1,404 reviews) The room was clean and the front desk staff is nice. I didn’t have any problems with check-in or check out. Reviewed on 25 Mar 2026 ## Santa Cruz Essential Information | Language | Spanish | | --------------- | ------------- | | Currency | Mexican pesos | | Local Welcome | ¡Hola! | | Local Goodbye | Adiós | | Population | 1,050 | | Max Temp Winter | 24ºC | | Max Temp Summer | 38ºC | ## Top hotels in Santa Cruz ![City Express by Marriott Nogales](https://images.trvl-media.com/lodging/5000000/4330000/4326700/4326618/d58a431d_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### City Express by Marriott Nogales Prolongacion Alvaro Obregon #4200 Nogales SON Fully refundableReserve now, pay when you stay £68 18 Apr - 19 Apr includes taxes & fees 8.4/10 Very Good! (1,000 reviews) Everyrhing excellent Reviewed on 22 Mar 2026 [](https://expedia.co.uk/Hotel-Search?startDate=18%2F04%2F2026&endDate=19%2F04%2F2026&selected=4326618&PinnedHotelID=4326618&HadPinnedHotel=true®ionId=553248635640644100) ![Fairfield Inn & Suites by Marriott Nogales](https://images.trvl-media.com/lodging/17000000/16260000/16255000/16254962/5f2606d2_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Fairfield Inn & Suites by Marriott Nogales Boulevard El Greco 45, Calle Arcadias Nogales SON Fully refundableReserve now, pay when you stay £98 11 Apr - 12 Apr includes taxes & fees 8.4/10 Very Good! (1,001 reviews) Parking good location good but room had no drinking water not even small bottle 200 bucks a night ! Compare to others at the same price range have water ! Reviewed on 21 Mar 2026 [](https://expedia.co.uk/Hotel-Search?startDate=11%2F04%2F2026&endDate=12%2F04%2F2026&selected=16254962&PinnedHotelID=16254962&HadPinnedHotel=true®ionId=553248635640644100) ![Fiesta Inn Nogales](https://images.trvl-media.com/lodging/2000000/1150000/1145700/1145669/2f093d92_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Fiesta Inn Nogales Calzada Ind Nuevo Nogales 3 Nogales SON Fully refundableReserve now, pay when you stay £88 10 Apr - 11 Apr includes taxes & fees 8.2/10 Very Good! (1,002 reviews) Cool Reviewed on 22 Mar 2026 [](https://expedia.co.uk/Hotel-Search?startDate=10%2F04%2F2026&endDate=11%2F04%2F2026&selected=1145669&PinnedHotelID=1145669&HadPinnedHotel=true®ionId=553248635640644100) [See all 22 properties in Santa Cruz](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=27%2F03%2F2026&endDate=28%2F03%2F2026®ionId=553248635640644100) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Holidays [](https://expedia.co.uk/lp/theme-holidays/all-inclusive-holidays?rfrr=editorial.All_Inclusive%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Holidays [](https://expedia.co.uk/lp/theme-holidays/beach-holidays?rfrr=editorial.Beach_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Friendly Holidays [](https://expedia.co.uk/lp/theme-holidays/kid-friendly-holidays?rfrr=editorial.Family_Friendly%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Holidays [](https://expedia.co.uk/lp/theme-holidays/golf-holidays?rfrr=editorial.Golf_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Holidays [](https://expedia.co.uk/lp/theme-holidays/luxury-holidays?rfrr=editorial.Luxury_Holidays.click) ![gay friendly holidays](https://forever.travel-assets.com/flex/flexmanager/images/2023/06/15/LGBTQIA_Holiday_Package.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) LGBTQ+ Holidays [](https://expedia.co.uk/lp/theme-holidays/gay-friendly-holidays?rfrr=editorial.LGBTQ+_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Holidays [](https://expedia.co.uk/lp/theme-holidays/romantic-holidays?rfrr=editorial.Romantic_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Holidays [](https://expedia.co.uk/lp/theme-holidays/ski-holidays?rfrr=editorial.Ski_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/22/hero-image-pet-friendly_copy.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Pet Friendly Holidays [](https://expedia.co.uk/lp/theme-holidays/pet-friendly-holidays?rfrr=editorial.Pet_Friendly%20Holidays.click) ![Holiday in Month](https://forever.travel-assets.com/flex/flexmanager/images/2023/05/10/mesog-34434-card-venice.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Where to go when [](https://expedia.co.uk/lp/b/where-to-go-when?rfrr=editorial.Where_to%20go%20when.click) ## Explore a world of travel with Expedia \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app