Santa Cruz do Douro Holidays from £164

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to £750 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Packages with flights are ATOL protected

Your Santa Cruz do Douro Holiday

Book a Santa Cruz do Douro holiday package and prepare for a fantastic adventure. Well known for its rich history and spectacular views, there's tons to like about this captivating city. Every trip to Santa Cruz do Douro needs a well-crafted itinerary. Fill yours with famous sights like Monastery of Santo André de Ancede, Baiao Municipal Museum and Garden of Saint Bartholomew. No matter your travel plans or budget, organising your ultimate tailored Santa Cruz do Douro holiday is a piece of cake with Expedia.

Top Santa Cruz do Douro Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
YOUROPO - Capela

YOUROPO - Capela

4 out of 5
Centro / Baixa
Save 100% on your flight
Price was £294, price is now £164 per person
£164
per person
3 Dec - 6 Dec
just found
Return flight included
London (LON) to Porto (OPO)
9.6/10 Exceptional! (74 reviews)
I am very satisfied with this accommodation. The location is very convenient. Check in on 7/24. The staff is very friendly. I will choose this place next time.

Reviewed on 26 Jan 2026

YOUROPO - Collection

YOUROPO - Collection

2 out of 5
Centro / Baixa
Price was £446, price is now £222 per person
£222
per person
4 Dec - 8 Dec
found 1 day ago
Return flight included
London (LON) to Porto (OPO)
8.6/10 Excellent! (14 reviews)
Great location. Except for the fact there is a massive building project on the adjoining wall. It would have been nice to know that before booking. As at 0800 the Roto Hammer’s start a massive concert is n jackhammering noises. And this project will be ongoing for some time. If this would have been known before hand? I wouldn’t have booked. As I spent a lifetime in construction and wanted to leave the noise behind me. In affection, the A/c is more of a suggestion as it wouldn’t cool the room off as it should. I also ended up having to empty the water collection for the a/c 3 times. If not? There would have been gallons of water spilled on the floor. This was not disclosed about having to preform preventative maintenance. Check in? Was after 1500, not by much, but then they are strict about Che k out time they should be as strict about check in time. For the price? The value just wasn’t there.

Reviewed on 9 Sept 2026

YOUROPO - Market

YOUROPO - Market

3 out of 5
Centro / Baixa
Save 100% on your flight
Price was £432, price is now £225 per person
£225
per person
4 Dec - 8 Dec
found 1 day ago
Return flight included
London (LON) to Porto (OPO)
9.8/10 Exceptional! (134 reviews)

YOUROPO - Santa Catarina

YOUROPO - Santa Catarina

4 out of 5
Centro / Baixa
Price was £354, price is now £186 per person
£186
per person
15 Jan - 17 Jan
found 14 hours ago
Return flight included
London (STN) to Porto (OPO)
9.2/10 Wonderful! (31 reviews)
I love everything about you. Only negative thing was the age of the property. I think you should start repairing the floor. They are a lot of things in the apartment which needs replacing. But overall we LOVED it.

Reviewed on 10 Jul 2026

River-view Apartment in Oporto for 4

River-view Apartment in Oporto for 4

2.5 out of 5
Centro / Baixa
Price was £1,003, price is now £544 per person
£544
per person
4 Dec - 8 Dec
found 1 day ago
Return flight included
London (LON) to Porto (OPO)
No reviews

Santa Cruz do Douro Essential Information

Language
Portuguese
Currency
Euros
Local Welcome
Olá
Local Goodbye
Adeus
Closest Airport
Viseu (VSE)
Max Temp Winter
10ºC
Max Temp Summer
27ºC
Top Sights
Monastery of Santo André de Ancede, Paroquial Church and Garden of Saint Bartholomew

Top hotels in Santa Cruz do Douro

Douro Palace Hotel Resort and Spa

Douro Palace Hotel Resort and Spa

4 out of 5
Lugar Do Carrapatelo Baiao
Fully refundableReserve now, pay when you stay
The price is £80 per night from 3 Nov to 4 Nov
£80
3 Nov - 4 Nov
includes taxes & fees
8.8/10 Excellent! (290 reviews)
"Excellent property. Great combination of modern amenities with an authentic local feel. Took advantage of the one hour River Boat activity for €30. Best value ever."

Reviewed on 29 Oct 2026

Douro Palace Hotel Resort and Spa
Crisol Régua Douro

Crisol Régua Douro

4 out of 5
Largo Da Estação Da Cp Peso da Régua
Fully refundableReserve now, pay when you stay
The price is £56 per night from 28 Nov to 29 Nov
£56
28 Nov - 29 Nov
includes taxes & fees
9/10 Wonderful! (263 reviews)
"Breakfast was good. My only complaint is not with the hotel but with Expedia. I booked a room with breakfast but did not check the receipt, only to arrive and be told that breakfast was not included. A google check exposed that this is due to a glitch that expedia is aware of."

Reviewed on 25 Oct 2026

Crisol Régua Douro
Six Senses Douro Valley

Six Senses Douro Valley

5 out of 5
Quinta de Vale Abraão Lamego
The price is £828 per night from 24 Nov to 25 Nov
£828
24 Nov - 25 Nov
includes taxes & fees
9.8/10 Exceptional! (269 reviews)
"Simply AMAZING!!! Everything was awesome!"

Reviewed on 27 Oct 2026

Six Senses Douro Valley
See all 968 properties in Santa Cruz do Douro
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

What to do in Santa Cruz do Douro

Pinhão to Régua: Douro Cruise with Lock, Wine & Tapas - 3h

Pinhão to Régua: Douro Cruise with Lock, Wine & Tapas - 3h

£47
per adult
Pinhão to Régua: Douro Cruise with Lock, Wine & Tapas - 3h
Douro Valley: 4x4 Safari and Vineyard Visit

Douro Valley: 4x4 Safari and Vineyard Visit

£51
per adult
Douro Valley: 4x4 Safari and Vineyard Visit
3H Pinhão to Régua Douro Cruise with Lock Wine and Tapas

3H Pinhão to Régua Douro Cruise with Lock Wine and Tapas

£63
per adult
3H Pinhão to Régua Douro Cruise with Lock Wine and Tapas
See all activities in Santa Cruz do Douro

Frequently asked questions

How much does a Santa Cruz do Douro travel package cost?
Say yes to new adventures with our Santa Cruz do Douro travel packages, which start from just £164. Handpick the flights and hotels that fit your travel plans. Then, add on some tours or activities for an amazing adventure.
If I'm not able to travel, can I cancel my Santa Cruz do Douro travel package?
Whether it's your flight or hotel, you can cancel or change it. Locked in your Santa Cruz do Douro travel package in the last 24 hours? You may be able to make changes at no cost. For bookings older than that, you may incur a fee from your hotel, airline or car rental company. For more information, look up our Customer Service Portal. We'll help you every step of the way.
How do I get a cheap travel package to Santa Cruz do Douro?
Bundle your hotel and flight bookings, throw in extras such as activities, and save with a Santa Cruz do Douro travel package. You won't just score superb discounts on your getaway — you'll have a world of choice within your reach too. When you book with Expedia, you can select from more than 550 airlines and 1,000,000 hotels around the world. Your next grand adventure begins right here, right now!
Does Expedia offer Book Now, Pay Later Santa Cruz do Douro holidays?
Your bank balance shouldn't stop you from taking a holiday, so Expedia has worked out a solution to help. Now that we've formed a partnership with online lender Klarna, it's easier than ever to book a fabulous getaway without using up all your savings. Klarna offers flexible payment options at checkout that take the stress out of budgeting for your trip. Consider one of these flexible payment options:

  • Pay monthly holidays: Klarna has manageable monthly payment plans that suit all types of budgets, so you can have that well-earned holiday sooner.
  • Pay in instalments holidays: With this Book Now, Pay Later option, Klarna makes it easy to pay for your holiday in multiple transactions.
  • Low deposit holidays: When you spot an incredible deal but your budget doesn't quite go that far, Klarna's low deposit holiday plan will help you lock in your getaway.

Where should I stay in Santa Cruz do Douro?
If you'll be visiting Monastery of Santo André de Ancede, maximize your time sightseeing and find someplace to stay close by. It's one of the most popular attractions in this area.
What are the top hotels in Santa Cruz do Douro?
Book a room at Douro Royal Valley Hotel & SPA. It's one of this area's most sought-after properties. Another top-rated option in Santa Cruz do Douro is Douro Palace Hotel Resort and Spa.
How far in advance should I book my Santa Cruz do Douro holiday?
It all depends on the air carrier, but you can usually compare international airfares on Expedia up to 12 months in advance. While it's generally recommended to book ahead of time, lucky customers occasionally nab a cheaper flight just weeks before the date of departure.
What does an Expedia Santa Cruz do Douro travel package include?
Expedia has everything you need to organise your Santa Cruz do Douro trip, but what your package looks like is totally up to you. Choose from any combination of flights, hotels and rental cars. In search of some tours or activities to keep you busy? Once you've made your booking, you can add them on too. Whatever your budget or style, there's a package to suit your needs.
What should I know before booking a Santa Cruz do Douro travel package?
Locking in all the parts of your holiday together is one of the easiest ways to save. Bundle your airfares, rental cars and hotels into a tidy little package. But you're not limited to hotels. Expedia has all sorts of properties, including holiday rentals like beachfront villas and spacious residences. The list goes on!
Can I choose my airline with a Santa Cruz do Douro Expedia travel package?
You sure can. We offer more than 550 airline partners across the globe, so select the carrier that best fits your travel preferences.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.