San Lorenzo Holidays

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    Save up to £750 when you book a flight and hotel together*

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  • Rest easy

    Packages with flights are ATOL protected

Your San Lorenzo Holiday

Answer the call of adventure with a customised holiday package to San Lorenzo. Wherever your travels take you and whatever you plan to do, prepare to discover a destination that'll make you truly feel alive. Your trip to San Lorenzo wouldn't be complete without checking out some of its best cities, such as Boca Chica, Cangrejal and Horconcitos. From the instant you book your San Lorenzo holiday to the second you come back home, Expedia has your back each step of the way.

Top San Lorenzo Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
Las Clementinas

Las Clementinas

3.5 out of 5
Casco Viejo
Price was £1,589, price is now £1,223 per person
£1,223
per person
15 Aug - 22 Aug
found 1 day ago
Return direct flight included
London (LON) to Panama City (PTY)
9.4/10 Exceptional! (194 reviews)
Amazing property. Beautiful rooms. We reserved two rooms because we have a large family. Both rooms were amazing. The front desk clerk was one of the kindest and sweetest people I’ve met in my life. Would definitely return.

Reviewed on 14 Jun 2026

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Save 100% on your flight
Price was £2,736, price is now £1,726 per person
£1,726
per person
6 Sept - 17 Sept
found 1 day ago
Return direct flight included
Manchester (MAN) to Panama City (PTY)
9.2/10 Wonderful! (1,008 reviews)
I really enjoyed the hotel. I enjoyed the food, drinks and entertainment. The pool was another matter, for such a top rated hotel the pool was worse than any other hotel I have stayed. In the pictures it looked beautiful but when we went up, it was very disappointed. Everything else was great. I really picked you guys because of the pool. I wanted to get in a pool but yours like I said disappointed me.

Reviewed on 19 Jun 2026

Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
San Francisco
Save 100% on your flight
Price was £2,273, price is now £1,481 per person
£1,481
per person
6 Sept - 17 Sept
found 1 day ago
Return direct flight included
Manchester (MAN) to Panama City (PTY)
8.4/10 Very Good! (1,553 reviews)
Convenient location & very good overall!

Reviewed on 20 Jun 2026

Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
San Francisco
Price was £1,781, price is now £1,275 per person
£1,275
per person
6 Sept - 17 Sept
found 1 day ago
Return direct flight included
Manchester (MAN) to Panama City (PTY)
9/10 Wonderful! (1,036 reviews)
The staff and just the overall ambiance of the environment was top tier

Reviewed on 15 Jun 2026

Hyatt Regency Panama City

Hyatt Regency Panama City

5 out of 5
Bella Vista
Price was £1,788, price is now £1,363 per person
£1,363
per person
6 Sept - 17 Sept
found 1 day ago
Return direct flight included
Manchester (MAN) to Panama City (PTY)
9.6/10 Exceptional! (331 reviews)
The location was perfect for its proximity to restaurants and shopping. The rooms were clean and modern. The beds were very comfortable. The Staff were Friendly, Respectful and Helpful. Not speaking the Language did not prevent us from getting our needs met. We stayed for 10days and enjoyed our time in this Hotel very much. I highly recommend.

Reviewed on 21 Jun 2026

San Lorenzo Essential Information

Language
Spanish
Currency
Panamanian balboas
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Enrique Malek Intl. Airport (DAV)

Top hotels in San Lorenzo

Bocas del Mar Hotel

Bocas del Mar Hotel

4 out of 5
Road to Boca Chica Boca Chica Chiriqui
The price is £165 per night from 30 Jun to 1 Jul
£165
30 Jun - 1 Jul
includes taxes & fees
9.6/10 Exceptional! (232 reviews)
"I had a great stay at this hotel. The room is pretty with a gorgeous. The whole hotel is beautiful, with a spectacular view of the sea and well manicured garden. The bed was very comfortable. Definitely worth it"

Reviewed on 11 Jun 2026

Bocas del Mar Hotel
Seagull Cove Resort

Seagull Cove Resort

3.5 out of 5
Calle Principal Boca Chica Chiriqui
The price is £124 per night from 28 Jun to 29 Jun
£124
28 Jun - 29 Jun
includes taxes & fees
9.6/10 Exceptional! (97 reviews)
"A very nice and secluded resort. It was quiet. I loved that each room was its own building."

Reviewed on 31 May 2026

Seagull Cove Resort
Isla Palenque Member of the Cayuga Collection

Isla Palenque Member of the Cayuga Collection

4 out of 5
Isla Palenque, Chiriqui Boca Chica
10/10 Exceptional! (7 reviews)
"Five star experience. Felt like we had our own private island. Food, service, and accomodations were top notch."

Reviewed on 29 Mar 2026

Get rates
Isla Palenque Member of the Cayuga Collection
See all 112 properties in San Lorenzo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

Frequently asked questions

How much does a San Lorenzo travel package cost?
Choose from any combination of flights, hotels and car rentals, and you can be holidaying in San Lorenzo from just £1,223. And the more you bundle, the more dollars you save. Your dream escape has never been so affordable.
If I'm not able to travel, can I cancel my San Lorenzo travel package?
Yes you can, and we're here to help. You may be able to cancel or amend your San Lorenzo travel package for free if you booked in the last 24 hours. However, you may incur a fee from your airline, hotel or car rental company if your booking is older than that. If life gets in the way of your holiday, browse our Customer Service Portal for further information.
How do I get a cheap travel package to San Lorenzo?
Combining your flight and hotel with Expedia won't just save valuable time — it'll save you a tidy sum too. A San Lorenzo travel package makes it a cinch to arrange the ideal trip. With more than 550 airlines around the world to choose from, finding convenient flights that fit your schedule won't be an issue. Not only that, we've got over 1,000,000 hotel options globally to take your pick of. Now that's choice! Whatever your budget, Expedia puts the world within your reach.
Does Expedia offer Book Now, Pay Later San Lorenzo holidays?
Your bank balance shouldn't stop you from going on holiday, so Expedia has come up with a solution to help. Now that we've joined forces with online lender Klarna, it's easier than ever to book a fabulous getaway without exhausting your savings. Klarna offers flexible payment options at checkout that take the worry out of budgeting for your escape. Consider one of these flexible payment options:

  • Pay monthly holidays: Make your holiday dreams a reality sooner with Klarna's manageable monthly instalment plans. If paying a little each month sounds right for you, pick this option at checkout.
  • Pay in instalments holidays: Into the idea of paying for your holiday in multiple transactions? Then check out this Book Now, Pay Later option with Klarna.
  • Low deposit holidays: Hitting the "book now" button is much easier with this option. Put down a small deposit on your escape and then start packing your bags.

How far in advance should I book my San Lorenzo holiday?
Browse Expedia to compare international airfares as early as possible. You can usually purchase a ticket up to 12 months before departure. If you can't find your preferred air carrier, or you've left things to the last minute, fear not. Cheap tickets to San Lorenzo occasionally appear a few weeks before departure.
What does an Expedia San Lorenzo travel package include?
Flights, rental cars and hotels, or any combination of them — it's your pick! Whether you're exploring San Lorenzo with the family or travelling by yourself, there's a bundle to suit every budget and style. Once you've made your booking, why not add on a couple of activities?
What should I know before booking a San Lorenzo travel package?
A travel package can be tailored to your budget and is a fantastic way to make your money go further. How little or much you include is completely up to you. Rental cars, hotels and flights — choose any combination that suits your style.
Can I choose my airline with a San Lorenzo Expedia travel package?
Yes, the choice is yours. We have access to over 550 partner airlines throughout the world, so you can design your San Lorenzo adventure according to your travel needs.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.