A rocky shoreline with waves crashing against it, palm trees, and a clear blue sky.

San Lorenzo Holidays

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to £750 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Packages with flights are ATOL protected

Your San Lorenzo Holiday

Answer the call of adventure with a customised holiday package to San Lorenzo. Wherever your travels take you and whatever you plan to do, prepare to discover a destination that'll make you truly feel alive. Your trip to San Lorenzo wouldn't be complete without checking out some of its best cities, such as Boca Chica, Cangrejal and Horconcitos. From the instant you book your San Lorenzo holiday to the second you come back home, Expedia has your back each step of the way.

Top destinations in San Lorenzo

The Latest San Lorenzo Holiday Packages

Price found within the past 48 hours. Click for updated prices.
  • 24 Jan - 30 Jan

    Aloft by Marriott Panama + Flight

    San Francisco
    6 nights
    3.5 star property
    8.8/10 - Excellent (1,014 reviews)
    "Everything"
    Reviewed November 9, 2026
    Return • London (LHR) - Panama City (PTY)
    LHR - PTY • 1 stop PTY - LHR • 2 stops
    £2,221
    £2,114
    per traveller
    found 23 hours ago
    Aloft by Marriott Panama
  • 24 Jan - 30 Jan

    Marriott Panama Hotel + Flight

    Panama City
    6 nights
    4.0 star property
    9.2/10 - Wonderful (1,004 reviews)
    Return • London (LHR) - Panama City (PTY)
    LHR - PTY • 1 stop PTY - LHR • 2 stops
    £2,492
    £2,292
    per traveller
    found 23 hours ago
    Marriott Panama Hotel
  • 24 Jan - 30 Jan

    Sheraton Grand Panama + Flight

    San Francisco
    6 nights
    4.0 star property
    8.8/10 - Excellent (1,000 reviews)
    "Room was clean and staff was helpful"
    Reviewed November 8, 2026
    Return • London (LHR) - Panama City (PTY)
    LHR - PTY • 1 stop PTY - LHR • 2 stops
    £2,395
    £2,217
    per traveller
    found 23 hours ago
    Sheraton Grand Panama
  • 24 Jan - 30 Jan

    The Westin Playa Bonita Panama + Flight

    Veracruz
    6 nights
    5.0 star property
    8.2/10 - Very good (1,003 reviews)
    Return • London (LHR) - Panama City (PTY)
    LHR - PTY • 1 stop PTY - LHR • 2 stops
    £2,590
    £2,436
    per traveller
    found 23 hours ago
    The Westin Playa Bonita Panama
  • 24 Jan - 30 Jan

    The Westin Panama + Flight

    Costa del Este
    6 nights
    4.0 star property
    9.0/10 - Wonderful (356 reviews)
    Return • London (LHR) - Panama City (PTY)
    LHR - PTY • 1 stop PTY - LHR • 2 stops
    £2,869
    £2,715
    per traveller
    found 23 hours ago
    The Westin Panama

Discover the most popular places to visit in San Lorenzo

San Lorenzo Hotel Deals

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently Asked Questions

How much does a San Lorenzo travel package cost?

Choose from any combination of flights, hotels and car rentals, and you can be holidaying in San Lorenzo from just £2,114. And the more you bundle, the more dollars you save. Your dream escape has never been so affordable.

If I'm not able to travel, can I cancel my San Lorenzo travel package?

Yes you can, and we're here to help. You may be able to cancel or amend your San Lorenzo travel package for free if you booked in the last 24 hours. However, you may incur a fee from your airline, hotel or car rental company if your booking is older than that. If life gets in the way of your holiday, browse our Customer Service Portal for further information.

How do I get a cheap travel package to San Lorenzo?

Combining your flight and hotel with Expedia won't just save valuable time — it'll save you a tidy sum too. A San Lorenzo travel package makes it a cinch to arrange the ideal trip. With more than 550 airlines around the world to choose from, finding convenient flights that fit your schedule won't be an issue. Not only that, we've got over 1,000,000 hotel options globally to take your pick of. Now that's choice! Whatever your budget, Expedia puts the world within your reach.

Does Expedia offer Book Now, Pay Later San Lorenzo holidays?

Your bank balance shouldn't stop you from going on holiday, so Expedia has come up with a solution to help. Now that we've joined forces with online lender Klarna, it's easier than ever to book a fabulous getaway without exhausting your savings. Klarna offers flexible payment options at checkout that take the worry out of budgeting for your escape. Consider one of these flexible payment options:

  • Pay monthly holidays: Make your holiday dreams a reality sooner with Klarna's manageable monthly instalment plans. If paying a little each month sounds right for you, pick this option at checkout.
  • Pay in instalments holidays: Into the idea of paying for your holiday in multiple transactions? Then check out this Book Now, Pay Later option with Klarna.
  • Low deposit holidays: Hitting the "book now" button is much easier with this option. Put down a small deposit on your escape and then start packing your bags.

How far in advance should I book my San Lorenzo holiday?

Browse Expedia to compare international airfares as early as possible. You can usually purchase a ticket up to 12 months before departure. If you can't find your preferred air carrier, or you've left things to the last minute, fear not. Cheap tickets to San Lorenzo occasionally appear a few weeks before departure.

What does an Expedia San Lorenzo travel package include?

Flights, rental cars and hotels, or any combination of them — it's your pick! Whether you're exploring San Lorenzo with the family or travelling by yourself, there's a bundle to suit every budget and style. Once you've made your booking, why not add on a couple of activities?

What should I know before booking a San Lorenzo travel package?

A travel package can be tailored to your budget and is a fantastic way to make your money go further. How little or much you include is completely up to you. Rental cars, hotels and flights — choose any combination that suits your style.

Can I choose my airline with a San Lorenzo Expedia travel package?

Yes, the choice is yours. We have access to over 550 partner airlines throughout the world, so you can design your San Lorenzo adventure according to your travel needs.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.