San Francisco Holidays from £505
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- Better togetherSave up to £750 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPackages with flights are ATOL protected
Top San Francisco Flight + Hotel Deals
Price found within the past 48 hours. Click for updated prices.
Central Hotel Panama Casco Viejo
Casco Viejo
£647
per person
2 Nov - 6 Nov
found 1 day ago
Return flight included
Kingston (KIN) to Panama City (PTY)
9/10 Wonderful! (1,012 reviews)
Great stay very clean quiet room. Restaurant downstairs and plenty other ones in the area. Accommodated me on a early check in. I would definitely stay here again 100 stars
Reviewed on 17 Sept 2026
Top hotels in San Francisco
Hotel Mykonos Panama
Panamerican Highway Nuevo Santiago Veraguas
Fully refundableReserve now, pay when you stay
£68
22 Sept - 23 Sept
includes taxes & fees
8.8/10 Excellent! (595 reviews)
"Me encantó mi estadía en Hotel Mykonos. La habitación fue muy cómoda, mis hijos disfrutaron muchísimo la piscina y el servicio fue excelente. ❤️ Lo que más me encantó fue la comida del restaurante. La amapola (piña colada virgen) estaba espectacular, ¡10/10! 🍍🥥 De las mejores que he probado en ..."
Reviewed on 15 Sept 2026
Hotel Gran David
Vía Interamericana Santiago Veraguas
Fully refundableReserve now, pay when you stay
£59
24 Sept - 25 Sept
includes taxes & fees
HOTEL VISTA LAGO
Rincón Largo La Pena Santiago de Veraguas
Fully refundableReserve now, pay when you stay
£63
19 Sept - 20 Sept
includes taxes & fees
9.4/10 Exceptional! (124 reviews)
"Balcony"
Reviewed on 5 Sept 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.
