Title: Hotels in San Francisco - Best San Francisco Hotels from £43 - Fully Refundable Options - Expedia.co.uk

[Holiday Rentals in San Francisco](https://expedia.co.uk/San-Francisco-Holiday-Rentals.d829297101453152256.Travel-Guide-HolidayRentals)[San Francisco Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-San-Francisco.d829297101453152256.Car-Hire-Guide)[San Francisco Holidays](https://expedia.co.uk/San-Francisco.d829297101453152256.Holidays-City-Breaks)

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## Check prices for these dates

Tonight

[19 Mar - 20 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=829297101453152256&startDate=2026-03-19&endDate=2026-03-20&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[20 Mar - 21 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=829297101453152256&startDate=2026-03-20&endDate=2026-03-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[20 Mar - 22 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=829297101453152256&startDate=2026-03-20&endDate=2026-03-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[27 Mar - 29 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=829297101453152256&startDate=2026-03-27&endDate=2026-03-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for San Francisco hotels

![Restaurant](https://images.trvl-media.com/lodging/28000000/27780000/27775700/27775675/32d16900.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/28000000/27780000/27775700/27775675/5979890b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/28000000/27780000/27775700/27775675/e928836a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Basic Cabin, 2 Queen Beds | Individually decorated, individually furnished, free WiFi, bed sheets](https://images.trvl-media.com/lodging/28000000/27780000/27775700/27775675/74d89026.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Anachoreo

[](https://www.expedia.co.uk/Santa-Fe-Hotels-Hotel-Anachoreo.h27775675.Hotel-Information)

Santa Fe

9.6/10

Exceptional

(40 reviews)

"Wonderful place at a beautiful stay . I can recommend it totally ! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Ingmar

[](https://www.expedia.co.uk/Santa-Fe-Hotels-Hotel-Anachoreo.h27775675.Hotel-Information)

![3 outdoor pools, free pool cabanas, pool umbrellas](https://images.trvl-media.com/lodging/6000000/5280000/5270400/5270392/1db3bbb0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/6000000/5280000/5270400/5270392/4cd8025e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/6000000/5280000/5270400/5270392/7fbc7d82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily cooked-to-order breakfast ](https://images.trvl-media.com/lodging/6000000/5280000/5270400/5270392/958a4066.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Mykonos Panama

[](https://www.expedia.co.uk/Santiago-Hotels-Hotel-Mykonos-Panama.h5270392.Hotel-Information)

Nuevo Santiago

8.8/10

Excellent

(560 reviews)

"Great place to stay. Everything is near."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Javier

£65

includes taxes & fees

28 Mar - 29 Mar

[](https://www.expedia.co.uk/Santiago-Hotels-Hotel-Mykonos-Panama.h5270392.Hotel-Information)

![Outdoor pool, free pool cabanas, pool umbrellas](https://images.trvl-media.com/lodging/13000000/12010000/12003400/12003378/bb11ab13.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior detail](https://images.trvl-media.com/lodging/13000000/12010000/12003400/12003378/ecb3f197.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior entrance](https://images.trvl-media.com/lodging/13000000/12010000/12003400/12003378/c8c4c0e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/13000000/12010000/12003400/12003378/04d6194c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Gran David

[](https://www.expedia.co.uk/Santiago-Hotels-Hotel-Gran-David.h12003378.Hotel-Information)

Santiago

8.6/10

Excellent

(381 reviews)

"Large clean rooms, comfortable beds, very quiet , secure parking on-site, excellent breakfast included "

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Alexandr

[](https://www.expedia.co.uk/Santiago-Hotels-Hotel-Gran-David.h12003378.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/96000000/95680000/95675300/95675257/34474832.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/96000000/95680000/95675300/95675257/a93eba24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Single Room | Desk, laptop workspace, free WiFi](https://images.trvl-media.com/lodging/96000000/95680000/95675300/95675257/0083006b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/96000000/95680000/95675300/95675257/cbea3453.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### HOTEL VISTA LAGO

[](https://www.expedia.co.uk/Nuevo-Santiago-Hotels-HOTEL-VISTA-LAGO.h95675257.Hotel-Information)

La Pena

9.4/10

Exceptional

(101 reviews)

"Great place to stay, quiet…"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Eduardo

£56

includes taxes & fees

26 Mar - 27 Mar

[](https://www.expedia.co.uk/Nuevo-Santiago-Hotels-HOTEL-VISTA-LAGO.h95675257.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/127000000/126980000/126979100/126979030/93dacf77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Economy Room | Bathroom | Shower, towels](https://images.trvl-media.com/lodging/127000000/126980000/126979100/126979030/7bf4aca3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Junior Studio Suite | Desk, blackout curtains, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/127000000/126980000/126979100/126979030/a09098b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Junior Studio Suite | Interior](https://images.trvl-media.com/lodging/127000000/126980000/126979100/126979030/7756c521.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Plaza Los Tucanes

[](https://www.expedia.co.uk/Nuevo-Santiago-Hotels-Hotel-Plaza-Los-Tucanes.h126979030.Hotel-Information)

Nuevo Santiago

£43

includes taxes & fees

21 Mar - 22 Mar

[](https://www.expedia.co.uk/Nuevo-Santiago-Hotels-Hotel-Plaza-Los-Tucanes.h126979030.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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## Top San Francisco Hotel Reviews

![Hotel Mykonos Panama](https://images.trvl-media.com/lodging/6000000/5280000/5270400/5270392/1db3bbb0_y.jpg)

### Hotel Mykonos Panama

10/10 Excellent

"Loved the live DJ (music by an awesome pool with swim up bar). A pleasant surprise 😊"

[](https://expedia.co.uk/Santiago-Hotels-Hotel-Mykonos-Panama.h5270392.Hotel-Information)

![Hotel Anachoreo](https://images.trvl-media.com/lodging/28000000/27780000/27775700/27775675/32d16900_y.jpg)

### Hotel Anachoreo

10/10 Excellent

"This is a great place to unwind and enjoy the spectacular view. The room was quiet, clean and comfortable. The breakfast was convenient and large. I highly recommend the massage. "

[](https://expedia.co.uk/Santa-Fe-Hotels-Hotel-Anachoreo.h27775675.Hotel-Information)

![Hotel Gran David](https://images.trvl-media.com/lodging/13000000/12010000/12003400/12003378/bb11ab13_y.jpg)

### Hotel Gran David

10/10 Excellent

"Mi experiencia reciente en el Hotel Gran David en Veraguas ha sido muy positiva, especialmente al notar una evolución muy favorable en comparación con mi estancia de hace tres años. El personal es sumamente amable y atento, lo que te hace sentir bienvenido desde el primer instante, y tanto las instalaciones como el buffet de desayuno son de excelente calidad. Como único punto a considerar, el hotel se encuentra justo a un costado de la Carretera Panamericana, por lo que el ruido del tráfico constante, especialmente de camiones pesados, puede ser notable; si eres de sueño ligero, recomiendo solicitar una habitación alejada de la carretera. Asimismo, la administración debería mejorar la señalización de sus estacionamientos, ya que existen plazas adicionales detrás del hotel que no resultan obvias al llegar. En general, es una opción muy sólida y recomendable en la zona por su gran servicio y oferta gastronómica."

[](https://expedia.co.uk/Santiago-Hotels-Hotel-Gran-David.h12003378.Hotel-Information)

![HOTEL VISTA LAGO](https://images.trvl-media.com/lodging/96000000/95680000/95675300/95675257/34474832_y.jpg)

### HOTEL VISTA LAGO

10/10 Excellent

"Great place to stay, quiet…"

[](https://expedia.co.uk/Nuevo-Santiago-Hotels-HOTEL-VISTA-LAGO.h95675257.Hotel-Information)

![Hotel Galería](https://images.trvl-media.com/lodging/28000000/27580000/27570800/27570722/7a530baa_y.jpg)

### Hotel Galería

10/10 Excellent

"Clean room, comfy bed. Great restaurant with a free breakfast. What more could two weary travelers want. "

[](https://expedia.co.uk/Santiago-Hotels-Hotel-Galeria.h27570722.Hotel-Information)

## More cheap stays in San Francisco

![La Qhia Eco Retreat](https://images.trvl-media.com/lodging/30000000/29440000/29430100/29430099/4d99e674_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### La Qhia Eco Retreat

Barriada el Cerro A 100 Mts De Santa Fe Veraguas

[Get rates](https://expedia.co.uk/Hotel-Search?startDate=02%2F04%2F2026&endDate=03%2F04%2F2026&selected=29430099&PinnedHotelID=29430099&HadPinnedHotel=true&regionId=829297101453152256)

[](https://expedia.co.uk/Santa-Fe-Hotels-La-Qhia-Eco-Retreat.h29430099.Hotel-Information)

![HOTEL PLAZA COROTÚ](https://images.trvl-media.com/lodging/112000000/111280000/111276700/111276682/1a9e698d_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### HOTEL PLAZA COROTÚ

Carr. Panamericana Santiago Provincia de Veraguas

[Get rates](https://expedia.co.uk/Hotel-Search?startDate=02%2F04%2F2026&endDate=03%2F04%2F2026&selected=111276682&PinnedHotelID=111276682&HadPinnedHotel=true&regionId=829297101453152256)

[](https://expedia.co.uk/Santiago-Hotels-HOTEL-PLAZA-COROTU.h111276682.Hotel-Information)

![Hostal Brisas Calobreñas](https://images.trvl-media.com/lodging/26000000/25090000/25087400/25087317/94ab9042_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Hostal Brisas Calobreñas

Calobre Calobre Veraguas

[Get rates](https://expedia.co.uk/Hotel-Search?startDate=02%2F04%2F2026&endDate=03%2F04%2F2026&selected=25087317&PinnedHotelID=25087317&HadPinnedHotel=true&regionId=829297101453152256)

[](https://expedia.co.uk/Calobre-Hotels-Hostal-Brisas-Calobrenas.h25087317.Hotel-Information)

![Rainforest Yasmin Hotel](https://images.trvl-media.com/lodging/37000000/36940000/36933100/36933045/af470a64_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Rainforest Yasmin Hotel

Veraguas Santa Fe Provincia de Veraguas

[Get rates](https://expedia.co.uk/Hotel-Search?startDate=02%2F04%2F2026&endDate=03%2F04%2F2026&selected=36933045&PinnedHotelID=36933045&HadPinnedHotel=true&regionId=829297101453152256)

[](https://expedia.co.uk/Santa-Fe-Hotels-Rainforest-Yasmin-Hotel.h36933045.Hotel-Information)

![Hostal Travelers](https://images.trvl-media.com/lodging/40000000/39700000/39692500/39692489/e21dd145_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Hostal Travelers

Santiago de Veraguas Santiago Veraguas

[Get rates](https://expedia.co.uk/Hotel-Search?startDate=02%2F04%2F2026&endDate=03%2F04%2F2026&selected=39692489&PinnedHotelID=39692489&HadPinnedHotel=true&regionId=829297101453152256)

10/10 Exceptional! (1 review)

[](https://expedia.co.uk/Santiago-Hotels-Hostal-Travelers.h39692489.Hotel-Information)

![Black Lion Inn](https://images.trvl-media.com/lodging/42000000/41380000/41373000/41372966/c3625268_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Black Lion Inn

Vía Interamericana La Mata Veraguas

[Get rates](https://expedia.co.uk/Hotel-Search?startDate=02%2F04%2F2026&endDate=03%2F04%2F2026&selected=41372966&PinnedHotelID=41372966&HadPinnedHotel=true&regionId=829297101453152256)

[](https://expedia.co.uk/La-Mata-Hotels-Black-Lion-Inn.h41372966.Hotel-Information)

## Frequently asked questions

### What is the best area to stay in San Francisco?

> This area offers a practical and central base for exploring the region. The main plaza is a focal point, often bustling with local activity, and the Iglesia de San Francisco de la Montaña, a historic landmark, is just steps away. You'll find local eateries and small shops within easy walking distance.
> 
>   
> For travellers seeking convenience and a local experience, staying near the plaza is ideal. It provides direct access to the main road network for day trips to nearby natural attractions like the Cerro Hoya National Park or the coast.

### When is the best time to go to San Francisco?

> This period offers consistently sunny days with comfortable temperatures, making it ideal for exploring the natural beauty of the region. You'll find the weather great for outdoor activities like hiking, birdwatching, and visiting local farms without the interruption of daily rainfall.
> 
>   
> For those planning to explore the surrounding countryside and engage in outdoor adventures, the dry season ensures clear skies and accessible trails. This is particularly good for travellers who value being active and want to make the most of the region's natural attractions, such as the nearby waterfalls and coffee plantations.
> 
>   
> While the wet season (May to November) brings lush greenery, it also means daily downpours, which can sometimes limit outdoor plans.

### Can I cancel my hotel reservation on Expedia?

### How can I save on a San Francisco hotel booking with Expedia?

### How much is the nightly rate at a San Francisco hotel?

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