Title: Hotels in San Francisco - Best San Francisco Hotels from £52 - Fully Refundable Options - Expedia.co.uk [Holiday Rentals in San Francisco](https://expedia.co.uk/San-Francisco-Holiday-Rentals.d829297101453152256.Travel-Guide-HolidayRentals)[San Francisco Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-San-Francisco.d829297101453152256.Car-Hire-Guide)[San Francisco Holidays](https://expedia.co.uk/San-Francisco.d829297101453152256.Holidays-City-Breaks) ![Default HTG hotel image](https://media.expedia.com/media/content/shared/images/travelguides/sem-hotels-tablet.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in San Francisco from £52 ![price find illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [16 Sept - 17 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=829297101453152256&startDate=2025-09-16&endDate=2025-09-17&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [17 Sept - 18 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=829297101453152256&startDate=2025-09-17&endDate=2025-09-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [19 Sept - 21 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=829297101453152256&startDate=2025-09-19&endDate=2025-09-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [26 Sept - 28 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=829297101453152256&startDate=2025-09-26&endDate=2025-09-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top 10 San Francisco hotels and places to stay ## Our top choices for San Francisco hotels ![Outdoor pool, free pool cabanas, pool umbrellas](https://images.trvl-media.com/lodging/13000000/12010000/12003400/12003378/5966cf9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic Area](https://images.trvl-media.com/lodging/13000000/12010000/12003400/12003378/1e4a88c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/13000000/12010000/12003400/12003378/05586004.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/13000000/12010000/12003400/12003378/ecb3f197.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Gran David Santiago 8.4/10 Very good (330) "Excellent place for family" [](https://www.expedia.co.uk/Santiago-Hotels-Hotel-Gran-David.h12003378.Hotel-Information) ![2 outdoor pools, open 7:00 AM to 5:00 PM, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/28000000/27580000/27570800/27570722/7a530baa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/28000000/27580000/27570800/27570722/b156cdc4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/28000000/27580000/27570800/27570722/439d7ad1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/28000000/27580000/27570800/27570722/b809e795.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Galería Nuevo Santiago 8.4/10 Very good (196) "Clean room and great breakfast. My kids enjoyed the pool." £52 includes taxes & fees 30 Sept - 1 Oct [](https://www.expedia.co.uk/Santiago-Hotels-Hotel-Galeria.h27570722.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/6000000/5280000/5270400/5270392/cdb98b1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Banquet hall](https://images.trvl-media.com/lodging/6000000/5280000/5270400/5270392/ad50cffd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 outdoor pools, free pool cabanas, pool umbrellas](https://images.trvl-media.com/lodging/6000000/5280000/5270400/5270392/f574b9ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 outdoor pools, free pool cabanas, pool umbrellas](https://images.trvl-media.com/lodging/6000000/5280000/5270400/5270392/9b80125f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Mykonos Panama Nuevo Santiago 8.8/10 Excellent (528) "Great location and service." £70 includes taxes & fees 28 Sept - 29 Sept [](https://www.expedia.co.uk/Santiago-Hotels-Hotel-Mykonos-Panama.h5270392.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/96000000/95680000/95675300/95675257/4e3dd11f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/96000000/95680000/95675300/95675257/w1080h571x0y5-5632f012.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/96000000/95680000/95675300/95675257/a93eba24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Single Room | Desk, laptop workspace, free WiFi](https://images.trvl-media.com/lodging/96000000/95680000/95675300/95675257/0083006b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### HOTEL VISTA LAGO La Pena 9.4/10 Exceptional (66) "Very clean, food was 10/10 " £62 includes taxes & fees 28 Sept - 29 Sept [](https://www.expedia.co.uk/Nuevo-Santiago-Hotels-HOTEL-VISTA-LAGO.h95675257.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/28000000/27780000/27775700/27775675/32d16900.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Cabin, 2 Queen Beds | Living area | Books](https://images.trvl-media.com/lodging/28000000/27780000/27775700/27775675/895da852.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Quadruple Room, 1 Bedroom, Private Bathroom, Garden View | Individually decorated, individually furnished, free WiFi, bed sheets](https://images.trvl-media.com/lodging/28000000/27780000/27775700/27775675/e974000e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/28000000/27780000/27775700/27775675/e928836a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Anachoreo Santa Fe 9.4/10 Exceptional (34) "Excellent Asian cuisine and great views of the mountains from the patio!" [](https://www.expedia.co.uk/Santa-Fe-Hotels-Hotel-Anachoreo.h27775675.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/30000000/29440000/29430100/29430099/efe9a595.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/30000000/29440000/29430100/29430099/w2109h2110x26y25-bea329a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/30000000/29440000/29430100/29430099/63df0f76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/30000000/29440000/29430100/29430099/4d99e674.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Qhia Eco Retreat Santa Fe 8.0/10 Very good (18) "Very noisy due to neighbouring roosters & dogs at night. Food good & easy access. " [](https://www.expedia.co.uk/Santa-Fe-Hotels-La-Qhia-Eco-Retreat.h29430099.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-09-30&endDate=2025-10-01®ionId=829297101453152256&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSan-Francisco-Hotels.d829297101453152256.Travel-Guide-Hotels)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSan-Francisco-Hotels.d829297101453152256.Travel-Guide-Hotels) ## Top San Francisco Hotel Reviews ![Hotel Gran David](//images.trvl-media.com/lodging/13000000/12010000/12003400/12003378/5966cf9c_y.jpg) ### Hotel Gran David 10/10 Excellent "Ok" [](https://expedia.co.uk/Santiago-Hotels-Hotel-Gran-David.h12003378.Hotel-Information) ![HOTEL VISTA LAGO](//images.trvl-media.com/lodging/96000000/95680000/95675300/95675257/4e3dd11f_y.jpg) ### HOTEL VISTA LAGO 10/10 Excellent "Very clean, food was 10/10 " [](https://expedia.co.uk/Nuevo-Santiago-Hotels-HOTEL-VISTA-LAGO.h95675257.Hotel-Information) ![Hotel Mykonos Panama](//images.trvl-media.com/lodging/6000000/5280000/5270400/5270392/cdb98b1d_y.jpg) ### Hotel Mykonos Panama 10/10 Excellent "Great location and service." [](https://expedia.co.uk/Santiago-Hotels-Hotel-Mykonos-Panama.h5270392.Hotel-Information) ![Hotel Galería](//images.trvl-media.com/lodging/28000000/27580000/27570800/27570722/7a530baa_y.jpg) ### Hotel Galería 10/10 Excellent "Clean room and great breakfast. My kids enjoyed the pool." [](https://expedia.co.uk/Santiago-Hotels-Hotel-Galeria.h27570722.Hotel-Information) ![Hotel Anachoreo](//images.trvl-media.com/lodging/28000000/27780000/27775700/27775675/32d16900_y.jpg) ### Hotel Anachoreo 10/10 Excellent "Phenomenal property, Cambodian meals, great property and excellent customer service. The views are breathtaking from almost every room and the on site garden is wonderful to walk in…..the owner is also the cook at night……WOW! Hope this area stays just like it is. " [](https://expedia.co.uk/Santa-Fe-Hotels-Hotel-Anachoreo.h27775675.Hotel-Information) ![La Qhia Eco Retreat](//images.trvl-media.com/lodging/30000000/29440000/29430100/29430099/efe9a595_y.jpg) ### La Qhia Eco Retreat 8/10 Good "Our room had some drawbacks, like many gaps between the roof and walls that enable insects to go inside, but we used our own mosquito net and we were safe to sleep quietly. The second night ants invaded our room, we were offered to be moved to another room, but we were ok with the solution to spray them as we weren't in the mood to pack all our belongings. Reynaldo who runs the hostel is really nice guy, very attentive, helpful and available any time of the day. He is also behind the local infocenter, that provides a good source of necessary info about all possible activities in Santa Fe. Food in hostel's restaurant was also good." [](https://expedia.co.uk/Santa-Fe-Hotels-La-Qhia-Eco-Retreat.h29430099.Hotel-Information) ![HOTEL PLAZA COROTÚ](//images.trvl-media.com/lodging/112000000/111280000/111276700/111276682/1a9e698d_y.jpg) ### HOTEL PLAZA COROTÚ 10/10 Excellent "They will wash and laundry for a reasonable fee." [](https://expedia.co.uk/Santiago-Hotels-HOTEL-PLAZA-COROTU.h111276682.Hotel-Information) ## More cheap stays in San Francisco ![La Qhia Eco Retreat](https://images.trvl-media.com/lodging/30000000/29440000/29430100/29430099/efe9a595_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### La Qhia Eco Retreat Barriada el Cerro A 100 Mts De, Santa Fe, Veraguas [Get rates](https://expedia.co.uk/Hotel-Search?startDate=30%2F09%2F2025&endDate=01%2F10%2F2025&selected=29430099&PinnedHotelID=29430099&HadPinnedHotel=true®ionId=829297101453152256) 7.8/10 Good! (18 reviews) [](https://expedia.co.uk/Santa-Fe-Hotels-La-Qhia-Eco-Retreat.h29430099.Hotel-Information) ![Cabana Vergara Santa Fe](https://images.trvl-media.com/lodging/109000000/108020000/108011300/108011213/w1440h1075x0y422-dda3f8cf_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Cabana Vergara Santa Fe Provincia de Veraguas, Panama, Panama £121 29 Sept - 30 Sept includes taxes & fees [](https://expedia.co.uk/Santa-Fe-Hotels-Cabana-Vergara-Santa-Fe.h108011213.Hotel-Information) ![HOTEL PLAZA COROTÚ](https://images.trvl-media.com/lodging/112000000/111280000/111276700/111276682/1a9e698d_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### HOTEL PLAZA COROTÚ Carr. Panamericana, Santiago, Provincia de Veraguas [Get rates](https://expedia.co.uk/Hotel-Search?startDate=30%2F09%2F2025&endDate=01%2F10%2F2025&selected=111276682&PinnedHotelID=111276682&HadPinnedHotel=true®ionId=829297101453152256) 9/10 Wonderful! (19 reviews) [](https://expedia.co.uk/Santiago-Hotels-HOTEL-PLAZA-COROTU.h111276682.Hotel-Information) ![Hostal Brisas Calobreñas](https://images.trvl-media.com/lodging/26000000/25090000/25087400/25087317/eb429eed_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hostal Brisas Calobreñas Calobre, Calobre, Veraguas [Get rates](https://expedia.co.uk/Hotel-Search?startDate=30%2F09%2F2025&endDate=01%2F10%2F2025&selected=25087317&PinnedHotelID=25087317&HadPinnedHotel=true®ionId=829297101453152256) [](https://expedia.co.uk/Calobre-Hotels-Hostal-Brisas-Calobrenas.h25087317.Hotel-Information) ![Charming 2-bedroom house in amazing Santiago with AC, WiFi cable phone](https://images.trvl-media.com/lodging/110000000/109330000/109329300/109329235/ec2faad8_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Charming 2-bedroom house in amazing Santiago with AC, WiFi cable phone Santiago, Provincia de Veraguas [Get rates](https://expedia.co.uk/Hotel-Search?startDate=30%2F09%2F2025&endDate=01%2F10%2F2025&selected=109329235&PinnedHotelID=109329235&HadPinnedHotel=true®ionId=829297101453152256) [](https://expedia.co.uk/Santiago-Hotels-Charming-2-Bedroom-House-In-Amazing-Santiago-With-AC.h109329235.Hotel-Information) ![Hostal Travelers](https://images.trvl-media.com/lodging/40000000/39700000/39692500/39692489/f749b804_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hostal Travelers Santiago de Veraguas, Paso las Tablas, Santiago, Veraguas [Get rates](https://expedia.co.uk/Hotel-Search?startDate=30%2F09%2F2025&endDate=01%2F10%2F2025&selected=39692489&PinnedHotelID=39692489&HadPinnedHotel=true®ionId=829297101453152256) [](https://expedia.co.uk/Santiago-Hotels-Hostal-Travelers.h39692489.Hotel-Information) ## Explore a world of travel with Expedia - 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