Title: San Cosme y Damian Travel Guide: Best of San Cosme y Damian, Itapúa Department Travel 2026 | Expedia.co.uk [Hotels in San Cosme y Damian](https://expedia.co.uk/San-Cosme-Y-Damian-Hotels.d6348319.Travel-Guide-Hotels)[Holiday Rentals in San Cosme y Damian](https://expedia.co.uk/San-Cosme-Y-Damian-Holiday-Rentals.d6348319.Travel-Guide-HolidayRentals)[San Cosme y Damian Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-San-Cosme-Y-Damian.d6348319.Car-Hire-Guide)[San Cosme y Damian Holidays](https://expedia.co.uk/San-Cosme-Y-Damian.d6348319.Holidays-City-Breaks) # San Cosme y Damian Travel Guide ## Tourist Guide ## Visit San Cosme y Damian Things to do - Top hotels in San Cosme y Damian - Top Holiday Rentals in San Cosme y Damian ![Carnaval Hotel Casino](https://images.trvl-media.com/lodging/13000000/12600000/12599700/12599683/3c7f3c91_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Carnaval Hotel Casino Av. Irrazabal, 750 Encarnacion £55 28 Dec - 29 Dec includes taxes & fees Stay at this spa hotel in Encarnacion. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the property condition in their reviews. Popular ... 9.2/10 Wonderful! (165 reviews) All was great , nice hotel , excellent staff, perfect location Reviewed on 11 Nov 2025 [](https://expedia.co.uk/Hotel-Search?startDate=28%2F12%2F2025&endDate=29%2F12%2F2025&selected=12599683&PinnedHotelID=12599683&HadPinnedHotel=true®ionId=6348319) ![Awa Resort Hotel](https://images.trvl-media.com/lodging/16000000/15370000/15363400/15363309/28eceae7_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Awa Resort Hotel Ruta 1 Km 367, Calles Tajy y Naranjal Encarnacion Stay at this spa resort in Encarnacion. Enjoy free breakfast, free Wi-Fi and free parking. Popular attractions Costanera de la Ciudad de Encarnacion Paraguay ... 8.8/10 Excellent! (118 reviews) Awesome stay !! Reviewed on 31 Aug 2025 [Get rates](https://expedia.co.uk/Hotel-Search?startDate=07%2F01%2F2026&endDate=08%2F01%2F2026&selected=15363309&PinnedHotelID=15363309&HadPinnedHotel=true®ionId=6348319) [](https://expedia.co.uk/Hotel-Search?startDate=07%2F01%2F2026&endDate=08%2F01%2F2026&selected=15363309&PinnedHotelID=15363309&HadPinnedHotel=true®ionId=6348319) ![Hotel Luxsur](https://images.trvl-media.com/lodging/14000000/13330000/13327300/13327276/fa70e6e0_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Luxsur Jorge Memmel 661 Encarnacion £57 7 Jan - 8 Jan 2026 includes taxes & fees Stay at this hotel in Encarnacion. Enjoy free breakfast, free Wi-Fi and free parking. Popular attractions Former House of Stroessner and Plaza de Armas are located ... 8.8/10 Excellent! (156 reviews) The breakfast was good. rooms were clean Reviewed on 6 Feb 2025 [](https://expedia.co.uk/Hotel-Search?startDate=07%2F01%2F2026&endDate=08%2F01%2F2026&selected=13327276&PinnedHotelID=13327276&HadPinnedHotel=true®ionId=6348319) [See all 33 properties in Itapúa Department](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=25%2F12%2F2025&endDate=26%2F12%2F2025®ionId=553248635975176941) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![Sun Hotel](https://images.trvl-media.com/lodging/43000000/42350000/42340300/42340209/297cb57c_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Sun Hotel Encarnacion Itapúa Stay at this business-friendly hotel in Encarnacion. Enjoy free breakfast, free Wi-Fi and free parking. Popular attractions Carnival Sambadrome and Costanera ... 9/10 Wonderful! (108 reviews) Front desk staff were not friendly or welcoming. Reviewed on 17 Mar 2025 [](https://expedia.co.uk/Encarnacion-Hotels-SUN-HOTEL.h42340209.Hotel-Information) ![Encarnacion](https://images.trvl-media.com/lodging/100000000/99340000/99335800/99335734/b913dd8c_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Encarnacion Carlos Antonio Lopez casi Curupayty Encarnacion Itapúa Department Stay at this aparthotel in Encarnacion. Enjoy free breakfast, free Wi-Fi and free parking. Popular attractions Plaza de Armas and Former House of Stroessner ... [](https://expedia.co.uk/Encarnacion-Hotels-Encarnacion.h99335734.Hotel-Information) ![2-bedroom building in delightful Encarnacion with fitness room, AC](https://images.trvl-media.com/lodging/120000000/119540000/119534500/119534486/25c4b279_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### 2-bedroom building in delightful Encarnacion with fitness room, AC Encarnación Itapúa Stay at this apartment in Encarnacion. Enjoy free Wi-Fi, a beach locale and laundry facilities. Popular attractions Carnival Sambadrome and Costanera de la Ciudad ... [](https://expedia.co.uk/Encarnacion-Hotels-2-Bedroom-Building-In-Delightful-Encarnacion-With-Fitness-Room.h119534486.Hotel-Information) [See all 33 properties in Itapúa Department](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience®ionId=553248635975176941&sort=VACATION_RENTAL) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check San Cosme y Damian hotel availability [Tonight ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6348319&startDate=2025-12-24&endDate=2025-12-25)[24 Dec - 25 Dec](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6348319&startDate=2025-12-24&endDate=2025-12-25) [Tomorrow night ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6348319&startDate=2025-12-25&endDate=2025-12-26)[25 Dec - 26 Dec](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6348319&startDate=2025-12-25&endDate=2025-12-26) [This weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6348319&startDate=26%2F12%2F2025&endDate=28%2F12%2F2025)[26 Dec - 28 Dec](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6348319&startDate=26%2F12%2F2025&endDate=28%2F12%2F2025) [Next weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6348319&startDate=02%2F01%2F2026&endDate=04%2F01%2F2026)[2 Jan - 4 Jan](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6348319&startDate=02%2F01%2F2026&endDate=04%2F01%2F2026) ### Popular places to visit #### Buenaventura Suarez Planetarium You can spend time exploring the galleries in Buenaventura Suarez Planetarium in San Cosme y Damian. Take in the museums while you're in the area. [](https://expedia.co.uk/Buenaventura-Suarez-Planetarium-Encarnacion.d553248621532463875.Attraction) #### Guarani Jesuit Ruins of San Cosme and San Damián Find out about the history of San Cosme y Damian when you take a trip to Guarani Jesuit Ruins of San Cosme and San Damián. Take in the museums while you're in the area. [](https://expedia.co.uk/Guarani-Jesuit-Ruins-Of-San-Cosme-And-San-Damian-San-Cosme-y-Damian.d812269535561961472.Attraction) ## Cities near San Cosme y Damian ![Misiones which includes views as well as a couple](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/80000/80252-Misiones-Province.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Posadas ## Explore a world of travel with Expedia - Accommodation - Packages - Other - [Bella Vista Hotels ](https://www.expedia.co.uk/Bella-Vista-Hotels.d6141312.Travel-Guide-Hotels) - [Hotels near Carnival Sambadrome ](https://www.expedia.co.uk/Carnival-Sambadrome-Hotels.0-l553248621532374355-0.Travel-Guide-Filter-Hotels) - [Encarnacion Hotels ](https://www.expedia.co.uk/Encarnacion-Hotels.d6141802.Travel-Guide-Hotels) - [Jesús Hotels ](https://www.expedia.co.uk/Jesus-Hotels.d6353265.Travel-Guide-Hotels) - [Santa María Hotels ](https://www.expedia.co.uk/Santa-Maria-Hotels.d553248635975867967.Travel-Guide-Hotels) - [Trinidad Hotels ](https://www.expedia.co.uk/Trinidad-Hotels.d6141611.Travel-Guide-Hotels) - [Encarnacion Holidays ](https://www.expedia.co.uk/Encarnacion.d6141802.Holidays-City-Breaks) - [Visit Encarnacion ](https://www.expedia.co.uk/Encarnacion.dx6141802) - [Jesús Holidays ](https://www.expedia.co.uk/Jesus.d6353265.Holidays-City-Breaks) - [Things to do in Encarnacion ](https://www.expedia.co.uk/Things-To-Do-In-Encarnacion.d6141802.Travel-Guide-Activities) - Cities near San Cosme y Damian [Posadas](https://expedia.co.uk/Posadas.dx2887)[Encarnacion](https://expedia.co.uk/Encarnacion.dx6141802)