Title: San Cosme y Damian Travel Guide: Best of San Cosme y Damian, Itapúa Department Travel 2026 | Expedia.co.uk [Hotels in San Cosme y Damian](https://expedia.co.uk/San-Cosme-Y-Damian-Hotels.d6348319.Travel-Guide-Hotels)[Holiday Rentals in San Cosme y Damian](https://expedia.co.uk/San-Cosme-Y-Damian-Holiday-Rentals.d6348319.Travel-Guide-HolidayRentals)[San Cosme y Damian Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-San-Cosme-Y-Damian.d6348319.Car-Hire-Guide)[San Cosme y Damian Holidays](https://expedia.co.uk/San-Cosme-Y-Damian.d6348319.Holidays-City-Breaks) # San Cosme y Damian Travel Guide ## Tourist Guide ## Visit San Cosme y Damian Things to do - Top hotels in San Cosme y Damian - Top Holiday Rentals in San Cosme y Damian ![Carnaval Hotel Casino](https://images.trvl-media.com/lodging/13000000/12600000/12599700/12599683/3c7f3c91_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Carnaval Hotel Casino Av. Irrazabal, 750 Encarnacion £55 28 Dec - 29 Dec includes taxes & fees Stay at this spa hotel in Encarnacion. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the property condition in their reviews. Popular ... 9.2/10 Wonderful! (165 reviews) All was great , nice hotel , excellent staff, perfect location Reviewed on 11 Nov 2025 [](https://expedia.co.uk/Hotel-Search?startDate=28%2F12%2F2025&endDate=29%2F12%2F2025&selected=12599683&PinnedHotelID=12599683&HadPinnedHotel=true®ionId=6348319) ![Awa Resort Hotel](https://images.trvl-media.com/lodging/16000000/15370000/15363400/15363309/28eceae7_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Awa Resort Hotel Ruta 1 Km 367, Calles Tajy y Naranjal Encarnacion Stay at this spa resort in Encarnacion. Enjoy free breakfast, free Wi-Fi and free parking. Popular attractions Costanera de la Ciudad de Encarnacion Paraguay ... 8.8/10 Excellent! (118 reviews) Awesome stay !! Reviewed on 31 Aug 2025 [Get rates](https://expedia.co.uk/Hotel-Search?startDate=07%2F01%2F2026&endDate=08%2F01%2F2026&selected=15363309&PinnedHotelID=15363309&HadPinnedHotel=true®ionId=6348319) [](https://expedia.co.uk/Hotel-Search?startDate=07%2F01%2F2026&endDate=08%2F01%2F2026&selected=15363309&PinnedHotelID=15363309&HadPinnedHotel=true®ionId=6348319) ![Hotel Luxsur](https://images.trvl-media.com/lodging/14000000/13330000/13327300/13327276/fa70e6e0_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Luxsur Jorge Memmel 661 Encarnacion £57 7 Jan - 8 Jan 2026 includes taxes & fees Stay at this hotel in Encarnacion. Enjoy free breakfast, free Wi-Fi and free parking. Popular attractions Former House of Stroessner and Plaza de Armas are located ... 8.8/10 Excellent! (156 reviews) The breakfast was good. rooms were clean Reviewed on 6 Feb 2025 [](https://expedia.co.uk/Hotel-Search?startDate=07%2F01%2F2026&endDate=08%2F01%2F2026&selected=13327276&PinnedHotelID=13327276&HadPinnedHotel=true®ionId=6348319) [See all 33 properties in Itapúa Department](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=25%2F12%2F2025&endDate=26%2F12%2F2025®ionId=553248635975176941) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![Sun Hotel](https://images.trvl-media.com/lodging/43000000/42350000/42340300/42340209/297cb57c_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Sun Hotel Encarnacion Itapúa Stay at this business-friendly hotel in Encarnacion. Enjoy free breakfast, free Wi-Fi and free parking. Popular attractions Carnival Sambadrome and Costanera ... 9/10 Wonderful! (108 reviews) Front desk staff were not friendly or welcoming. Reviewed on 17 Mar 2025 [](https://expedia.co.uk/Encarnacion-Hotels-SUN-HOTEL.h42340209.Hotel-Information) ![Encarnacion](https://images.trvl-media.com/lodging/100000000/99340000/99335800/99335734/b913dd8c_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Encarnacion Carlos Antonio Lopez casi Curupayty Encarnacion Itapúa Department Stay at this aparthotel in Encarnacion. Enjoy free breakfast, free Wi-Fi and free parking. Popular attractions Plaza de Armas and Former House of Stroessner ... [](https://expedia.co.uk/Encarnacion-Hotels-Encarnacion.h99335734.Hotel-Information) ![2-bedroom building in delightful Encarnacion with fitness room, AC](https://images.trvl-media.com/lodging/120000000/119540000/119534500/119534486/25c4b279_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### 2-bedroom building in delightful Encarnacion with fitness room, AC Encarnación Itapúa Stay at this apartment in Encarnacion. Enjoy free Wi-Fi, a beach locale and laundry facilities. Popular attractions Carnival Sambadrome and Costanera de la Ciudad ... [](https://expedia.co.uk/Encarnacion-Hotels-2-Bedroom-Building-In-Delightful-Encarnacion-With-Fitness-Room.h119534486.Hotel-Information) [See all 33 properties in Itapúa Department](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience®ionId=553248635975176941&sort=VACATION_RENTAL) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check San Cosme y Damian hotel availability [Tonight ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6348319&startDate=2025-12-24&endDate=2025-12-25)[24 Dec - 25 Dec](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6348319&startDate=2025-12-24&endDate=2025-12-25) [Tomorrow night ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6348319&startDate=2025-12-25&endDate=2025-12-26)[25 Dec - 26 Dec](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6348319&startDate=2025-12-25&endDate=2025-12-26) [This weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6348319&startDate=26%2F12%2F2025&endDate=28%2F12%2F2025)[26 Dec - 28 Dec](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6348319&startDate=26%2F12%2F2025&endDate=28%2F12%2F2025) [Next weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6348319&startDate=02%2F01%2F2026&endDate=04%2F01%2F2026)[2 Jan - 4 Jan](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6348319&startDate=02%2F01%2F2026&endDate=04%2F01%2F2026) ### Popular places to visit #### Buenaventura Suarez Planetarium You can spend time exploring the galleries in Buenaventura Suarez Planetarium in San Cosme y Damian. Take in the museums while you're in the area. [](https://expedia.co.uk/Buenaventura-Suarez-Planetarium-Encarnacion.d553248621532463875.Attraction) #### Guarani Jesuit Ruins of San Cosme and San Damián Find out about the history of San Cosme y Damian when you take a trip to Guarani Jesuit Ruins of San Cosme and San Damián. Take in the museums while you're in the area. [](https://expedia.co.uk/Guarani-Jesuit-Ruins-Of-San-Cosme-And-San-Damian-San-Cosme-y-Damian.d812269535561961472.Attraction) ## Cities near San Cosme y Damian ![Misiones which includes views as well as a couple](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/80000/80252-Misiones-Province.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Posadas ## Explore a world of travel with Expedia - Accommodation - Packages - Other - [Bella Vista Hotels ](https://www.expedia.co.uk/Bella-Vista-Hotels.d6141312.Travel-Guide-Hotels) - [Hotels near Carnival Sambadrome ](https://www.expedia.co.uk/Carnival-Sambadrome-Hotels.0-l553248621532374355-0.Travel-Guide-Filter-Hotels) - [Encarnacion Hotels ](https://www.expedia.co.uk/Encarnacion-Hotels.d6141802.Travel-Guide-Hotels) - [Jesús Hotels ](https://www.expedia.co.uk/Jesus-Hotels.d6353265.Travel-Guide-Hotels) - [Santa María Hotels ](https://www.expedia.co.uk/Santa-Maria-Hotels.d553248635975867967.Travel-Guide-Hotels) - [Trinidad Hotels ](https://www.expedia.co.uk/Trinidad-Hotels.d6141611.Travel-Guide-Hotels) - [Encarnacion Holidays ](https://www.expedia.co.uk/Encarnacion.d6141802.Holidays-City-Breaks) - [Visit Encarnacion ](https://www.expedia.co.uk/Encarnacion.dx6141802) - [Jesús Holidays ](https://www.expedia.co.uk/Jesus.d6353265.Holidays-City-Breaks) - [Things to do in Encarnacion ](https://www.expedia.co.uk/Things-To-Do-In-Encarnacion.d6141802.Travel-Guide-Activities) - Cities near San Cosme y Damian [Posadas](https://expedia.co.uk/Posadas.dx2887)[Encarnacion](https://expedia.co.uk/Encarnacion.dx6141802) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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