Title: San Cosme y Damian Travel Guide: Best of San Cosme y Damian, Itapúa Department Travel 2025 | Expedia.co.uk [Hotels in San Cosme y Damian](https://expedia.co.uk/San-Cosme-Y-Damian-Hotels.d6348319.Travel-Guide-Hotels)[Holiday Rentals in San Cosme y Damian](https://expedia.co.uk/San-Cosme-Y-Damian-Holiday-Rentals.d6348319.Travel-Guide-HolidayRentals)[San Cosme y Damian Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-San-Cosme-Y-Damian.d6348319.Car-Hire-Guide)[San Cosme y Damian Holidays](https://expedia.co.uk/San-Cosme-Y-Damian.d6348319.Holidays-City-Breaks) # San Cosme y Damian Travel Guide ## Tourist Guide ## Visit San Cosme y Damian Things to do - Top hotels in San Cosme y Damian - Top Holiday Rentals in San Cosme y Damian ![Awa Resort Hotel](https://images.trvl-media.com/lodging/16000000/15370000/15363400/15363309/28eceae7_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Awa Resort Hotel Ruta 1 Km 367, Calles Tajy y Naranjal, Encarnacion Stay at this 4-star spa resort in Encarnacion. Enjoy free breakfast, free Wi-Fi and free parking. Popular attractions Costanera de la Ciudad de Encarnacion Paraguay ... 8.8/10 Excellent! (111 reviews) "Awesome stay !!" Reviewed on 31 Aug 2025 [Get rates](https://expedia.co.uk/Hotel-Search?startDate=07%2F10%2F2025&endDate=08%2F10%2F2025&selected=15363309&PinnedHotelID=15363309&HadPinnedHotel=true®ionId=6348319) [](https://expedia.co.uk/Hotel-Search?startDate=07%2F10%2F2025&endDate=08%2F10%2F2025&selected=15363309&PinnedHotelID=15363309&HadPinnedHotel=true®ionId=6348319) ![Carnaval Hotel Casino](https://images.trvl-media.com/lodging/13000000/12600000/12599700/12599683/3c7f3c91_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Carnaval Hotel Casino Av. Irrazabal, 750, Encarnacion £53 24 Sept - 25 Sept includes taxes & fees Stay at this 3.5-star spa hotel in Encarnacion. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the property condition in their reviews. ... 9.2/10 Wonderful! (149 reviews) "We had a very pleasant stay at Carnaval Hotel Casino. The staff was consistently friendly, professional, and helpful throughout our visit. Everything was clean and well-organized, and we felt well taken care of. Thank you for the great service. We hope to return in the future." Reviewed on 9 Jun 2025 [](https://expedia.co.uk/Hotel-Search?startDate=24%2F09%2F2025&endDate=25%2F09%2F2025&selected=12599683&PinnedHotelID=12599683&HadPinnedHotel=true®ionId=6348319) ![Hotel Luxsur](https://images.trvl-media.com/lodging/14000000/13330000/13327300/13327276/fa70e6e0_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Luxsur Jorge Memmel 661, c/ Independencia Nacional, Encarnacion Fully refundableReserve now, pay when you stay £56 29 Sept - 30 Sept includes taxes & fees Stay at this 3.5-star hotel in Encarnacion. Enjoy free breakfast, free Wi-Fi and free parking. Popular attractions Former House of Stroessner and Plaza de Armas ... 8.8/10 Excellent! (148 reviews) "The breakfast was good. rooms were clean" Reviewed on 6 Feb 2025 [](https://expedia.co.uk/Hotel-Search?startDate=29%2F09%2F2025&endDate=30%2F09%2F2025&selected=13327276&PinnedHotelID=13327276&HadPinnedHotel=true®ionId=6348319) [See all 31 properties in Itapúa Department](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=24%2F09%2F2025&endDate=25%2F09%2F2025®ionId=553248635975176941) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![Sun Hotel](https://images.trvl-media.com/lodging/43000000/42350000/42340300/42340209/297cb57c_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Sun Hotel Encarnacion, Itapúa Stay at this 3.5-star business-friendly hotel in Encarnacion. Enjoy free breakfast, free Wi-Fi and free parking. Popular attractions Carnival Sambadrome and ... 9/10 Wonderful! (108 reviews) "Front desk staff were not friendly or welcoming." Reviewed on 17 Mar 2025 [](https://expedia.co.uk/Encarnacion-Hotels-SUN-HOTEL.h42340209.Hotel-Information) ![Encarnacion](https://images.trvl-media.com/lodging/100000000/99340000/99335800/99335734/b913dd8c_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Encarnacion Carlos Antonio Lopez casi Curupayty, 1055, Encarnacion, Itapúa Department Stay at this 3-star aparthotel in Encarnacion. Enjoy free breakfast, free Wi-Fi and free parking. Popular attractions Plaza de Armas and Former House of Stroessner ... [](https://expedia.co.uk/Encarnacion-Hotels-Encarnacion.h99335734.Hotel-Information) ![Habitación en Alquiler en el Centro de Encarnación con Baño Privado. Wifi Aire](https://images.trvl-media.com/lodging/108000000/107060000/107053200/107053154/3c6bb15e_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Habitación en Alquiler en el Centro de Encarnación con Baño Privado. Wifi Aire Encarnación Stay at this apartment in Encarnacion. Enjoy air conditioning. Popular attractions Former House of Stroessner and Plaza de Armas are located nearby. [](https://expedia.co.uk/Encarnacion-Hotels-Habitacion-En-Alquiler-En-El-Centro-De-Encarnacion-Con-Bano-Privado-Wifi-Aire.h107053154.Hotel-Information) [See all 31 properties in Itapúa Department](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience®ionId=553248635975176941&sort=VACATION_RENTAL) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check San Cosme y Damian hotel availability [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6348319&startDate=2025-09-23&endDate=2025-09-24) [Tonight](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6348319&startDate=2025-09-23&endDate=2025-09-24) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6348319&startDate=2025-09-23&endDate=2025-09-24) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6348319&startDate=2025-09-23&endDate=2025-09-24)[23 Sept - 24 Sept](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6348319&startDate=2025-09-23&endDate=2025-09-24) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6348319&startDate=2025-09-24&endDate=2025-09-25) [Tomorrow night](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6348319&startDate=2025-09-24&endDate=2025-09-25) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6348319&startDate=2025-09-24&endDate=2025-09-25) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6348319&startDate=2025-09-24&endDate=2025-09-25)[24 Sept - 25 Sept](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6348319&startDate=2025-09-24&endDate=2025-09-25) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6348319&startDate=26%2F09%2F2025&endDate=28%2F09%2F2025) [This weekend](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6348319&startDate=26%2F09%2F2025&endDate=28%2F09%2F2025) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6348319&startDate=26%2F09%2F2025&endDate=28%2F09%2F2025) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6348319&startDate=26%2F09%2F2025&endDate=28%2F09%2F2025)[26 Sept - 28 Sept](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6348319&startDate=26%2F09%2F2025&endDate=28%2F09%2F2025) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6348319&startDate=03%2F10%2F2025&endDate=05%2F10%2F2025) [Next weekend](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6348319&startDate=03%2F10%2F2025&endDate=05%2F10%2F2025) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6348319&startDate=03%2F10%2F2025&endDate=05%2F10%2F2025) [](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6348319&startDate=03%2F10%2F2025&endDate=05%2F10%2F2025)[3 Oct - 5 Oct](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6348319&startDate=03%2F10%2F2025&endDate=05%2F10%2F2025) ### Popular places to visit #### Buenaventura Suarez Planetarium You can spend time exploring the galleries in Buenaventura Suarez Planetarium in San Cosme y Damian. Take in the museums while you're in the area. [](https://expedia.co.uk/Buenaventura-Suarez-Planetarium-Encarnacion.d553248621532463875.Attraction) #### Guarani Jesuit Ruins of San Cosme and San Damián Find out about the history of San Cosme y Damian when you take a trip to Guarani Jesuit Ruins of San Cosme and San Damián. Take in the museums while you're in the area. [](https://expedia.co.uk/Guarani-Jesuit-Ruins-Of-San-Cosme-And-San-Damian-San-Cosme-y-Damian.d812269535561961472.Attraction) ## Explore a world of travel with Expedia - Accommodation - Packages - Other - [Bella Vista Hotels](https://www.expedia.co.uk/Bella-Vista-Hotels.d6141312.Travel-Guide-Hotels) - [Hotels near Carnival Sambadrome](https://www.expedia.co.uk/Carnival-Sambadrome-Hotels.0-l553248621532374355-0.Travel-Guide-Filter-Hotels) - [Encarnacion Hotels](https://www.expedia.co.uk/Encarnacion-Hotels.d6141802.Travel-Guide-Hotels) - [Jesús Hotels](https://www.expedia.co.uk/Jesus-Hotels.d6353265.Travel-Guide-Hotels) - [Santa María Hotels](https://www.expedia.co.uk/Santa-Maria-Hotels.d553248635975867967.Travel-Guide-Hotels) - [Trinidad Hotels](https://www.expedia.co.uk/Trinidad-Hotels.d6141611.Travel-Guide-Hotels) - [Encarnacion Holidays](https://www.expedia.co.uk/Encarnacion.d6141802.Holidays-City-Breaks) - [Visit Encarnacion](https://www.expedia.co.uk/Encarnacion.dx6141802) - [Jesús Holidays](https://www.expedia.co.uk/Jesus.d6353265.Holidays-City-Breaks) - [Things to do in Encarnacion](https://www.expedia.co.uk/Things-To-Do-In-Encarnacion.d6141802.Travel-Guide-Activities) - Cities near San Cosme y Damian [Posadas](https://expedia.co.uk/Posadas.dx2887)[Encarnacion](https://expedia.co.uk/Encarnacion.dx6141802) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,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)