A staircase with colorful tiles leading up to a wall with a sign reading "La Villita, Little Village of San Antonio".

Find hotels in San Antonio, FL from £52

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Save instantly and earn perks with One Key
    Learn about One Key

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
9 Sept - 10 Sept
Tomorrow
10 Sept - 11 Sept
This weekend
11 Sept - 13 Sept
Next weekend
18 Sept - 20 Sept

Filter by

Star rating

Guest rating

Our top choices for San Antonio hotels

A reception area with a wooden reception desk, a welcome sign, a counter with a cash register, and a door to the right.
A Hampton Inn hotel with a clear entrance, a sign above the entrance, and a handicap accessibility sign.
A kitchen area with a chalkboard menu, waffle station, and various kitchen appliances.
A hotel room with two beds, a desk, a TV, and a window with blinds.

1. Hampton Inn Dade City - Zephyrhills

Hampton Inn Dade City - Zephyrhills
Dade City
United States
Jeannie
£81
includes taxes & fees
20 Sept - 21 Sept
Hampton Inn Dade City - Zephyrhills
A hotel room with a large bed, a sofa, a coffee table, a desk, and a window with curtains.
A reception desk at the Roadstar Hotel with a clock, a digital screen, and a sign indicating breakfast availability.
A spacious lobby with a beige sofa, two armchairs, a coffee table, and a large potted plant.
A gazebo with a bench in a well-maintained grassy area, surrounded by palm trees and a building with a tiled roof.

2. Roadstar Hotel Zephyrhills

Roadstar Hotel Zephyrhills
Zephyrhills
United States
Juan
£60
includes taxes & fees
15 Sept - 16 Sept
Roadstar Hotel Zephyrhills
A Quality Inn with a white exterior, a covered entrance, and a signboard.
A hotel room with a bed, a desk, a chair, a TV, and a window with curtains.
A hotel lobby with a reception desk, a staircase, and a view of the kitchen area.
A modern office space with two desks, each equipped with a computer monitor, keyboard, and mouse. There are two office chairs, a printer, and two potted plants on the desks. A framed artwork hangs on the wall above the desks.

3. Quality Inn Zephyrhills-dade City

Quality Inn Zephyrhills-dade City
Zephyrhills
United States
Joyce
£58
includes taxes & fees
20 Sept - 21 Sept
Quality Inn Zephyrhills-dade City
A multi-story hotel with a parking lot and a small building with a sign.
A conference room with long tables and chairs, a large flat-screen TV on the wall, and windows with curtains.
A swimming pool with a white fence, a building with a gabled roof, and palm trees in the background.
A dining area with tables and chairs, a kitchen in the background, and a flat-screen TV mounted on the wall.

4. Microtel Inn & Suites by Wyndham Zephyrhills

Microtel Inn & Suites by Wyndham Zephyrhills
Zephyrhills
United States
Edward
£76
includes taxes & fees
11 Sept - 12 Sept
Microtel Inn & Suites by Wyndham Zephyrhills
A swimming pool with a metal ladder, lounge chairs, and a white fence.
A pool table with balls and cues, a sofa with orange cushions, and two framed sports jerseys on the wall.

5. Spot X Hotel Wesley Chapel - Tampa Area

Spot X Hotel Wesley Chapel - Tampa Area
Wesley Chapel
United States
Wilfred
£70
includes taxes & fees
24 Sept - 25 Sept
Spot X Hotel Wesley Chapel - Tampa Area
A Best Western hotel with a prominent sign, multiple floors, and a well-lit entrance.
A modern reception area with a teal-tiled backsplash, a wooden counter, and a green office chair.
A hotel room with a large bed, a desk, a chair, and a nightstand with lamps.
A spacious lobby with a reception desk, green armchairs, a round white ottoman, and a green sofa with patterned cushions.

6. Best Western Wesley Chapel

Best Western Wesley Chapel
Wesley Chapel
United States
Charles
£78
includes taxes & fees
23 Sept - 24 Sept
Best Western Wesley Chapel
A playground area with a sign for "Two Naked Monkey's Bar" and a wooden structure with a curved roof.
A fountain in a landscaped area with a pool, surrounded by grass and a paved walkway.
A streetcar named Desire parked on grass with a building and trees in the background.
A compact bedroom with a bed, a small kitchenette, and a bathroom visible through an open door.

7. Liberty Hill Executive Inn

Liberty Hill Executive Inn
Zephyrhills
United States
Ken
£56
includes taxes & fees
13 Sept - 14 Sept
Liberty Hill Executive Inn
A patio with two chairs and a table, overlooking a pond with lily pads and a grassy area with trees.
An aerial view of a golf course with a pond, surrounded by buildings with blue roofs, and dense greenery.
A modern hotel room with a large window, a dining area, and a bathroom with a sink.
A room with a view of a pond, a wicker chair, a table with a cup and pastries, and a lamp.

8. Saddlebrook Resort

Saddlebrook Resort
Wesley Chapel South
United States
Diane
£131
includes taxes & fees
1 Oct - 2 Oct
Saddlebrook Resort
A spacious dining area with high tables and green chairs, large windows with a city view, and a modern ceiling design.
A hotel room with two beds, a desk, a chair, a window with curtains, and a wall-mounted lamp.
A room with a red sofa, two side tables with lamps, a wooden coffee table, a chair, and a window with blue curtains.
A modern lobby with a glass door entrance, a reception desk, and decorative wall art.

9. Rodeway Inn Wesley Chapel

Rodeway Inn Wesley Chapel
Wesley Chapel
United States
Janet
£63
includes taxes & fees
30 Sept - 1 Oct
Rodeway Inn Wesley Chapel
A pool with a stone waterfall feature, surrounded by rocks and palm trees.
A large tree with Spanish moss, a picnic table, and a trash can in a grassy area.
A spacious living room with a sofa, armchair, and a coffee table. There are two windows providing natural light and a view of greenery outside.
A modern lounge area with a sofa, a vending machine, and a view of a garden through large windows.

10. Days Inn by Wyndham Brooksville/Dade City

Days Inn by Wyndham Brooksville/Dade City
Brooksville
United States
Michael
£60
includes taxes & fees
27 Sept - 28 Sept
Days Inn by Wyndham Brooksville/Dade City
A hotel lobby with a bar area, seating arrangements, and a television screen.
A hotel room with a bed, a desk, a chair, a TV, and a mirror.
A hotel room with a seating area, a dining table, and a large window with curtains.
A hotel room with a bed, a desk with a television, a lamp, and a microwave.

11. Hampton Inn Brooksville Dade

Hampton Inn Brooksville Dade
Brooksville
United States
Sue
£77
includes taxes & fees
18 Sept - 19 Sept
Hampton Inn Brooksville Dade
A coffee station with two coffee machines, a coffee press, and various coffee-related items on a wooden counter.
A hotel room with two beds, a TV, a desk, and a bathroom visible through an archway.
A hotel room with a television, a desk, a chair, a sofa, and a bed.
A breakfast bar with labeled sections for cereal and fruit, a blue oatmeal container, and condiments.

12. Holiday Inn Express Hotel & Suites Brooksville by IHG

Holiday Inn Express Hotel & Suites Brooksville by IHG
Brooksville
United States
Ricarda
£77
includes taxes & fees
21 Sept - 22 Sept
Holiday Inn Express Hotel & Suites Brooksville by IHG
A rectangular swimming pool with clear blue water, surrounded by lounge chairs and a stone wall.
A Fairfield Inn by Marriott hotel with a parking lot and a well-lit entrance.
A reception area with a wooden reception desk, a wall-mounted display, and a door in the background.

13. Fairfield Inn & Suites by Marriott Tampa Wesley Chapel

Fairfield Inn & Suites by Marriott Tampa Wesley Chapel
Wesley Chapel
United States
peyton
£89
includes taxes & fees
23 Sept - 24 Sept
Fairfield Inn & Suites by Marriott Tampa Wesley Chapel
A hotel room with a large bed, a desk, a chair, a window with curtains, a flat-screen TV, a mirror, and a wall-mounted shelf.
A reception area with a dark reception desk, a glass door entrance, and a sign for 'Michael Inn & Suites'.
A modern lobby with a seating area, a TV mounted on the wall, and a visible kitchen area in the background.
A compact hotel room with a kitchenette, a bed, a TV, and a seating area.

14. Microtel Inn & Suites by Wyndham Brooksville

Microtel Inn & Suites by Wyndham Brooksville
Brooksville
United States
Danielle
£68
includes taxes & fees
11 Oct - 12 Oct
Microtel Inn & Suites by Wyndham Brooksville
A lobby with a reception desk, seating area with chairs and a table, and a large window with curtains.
A hotel room with a bed, a desk, a chair, a television, and a window with curtains.
A swimming pool with a white fence, lounge chairs, and a palm tree in the background.
A large building with a central tower, multiple windows, and a parking lot in front.

15. Econo Lodge Wesley Chapel I-75

Econo Lodge Wesley Chapel I-75
Wesley Chapel
United States
Milton
£66
includes taxes & fees
30 Sept - 1 Oct
Econo Lodge Wesley Chapel I-75
A hotel with a modern architectural design, featuring a spacious outdoor seating area with tables and chairs, a curved driveway, and a parking lot.
A modern kitchen with white cabinets, a central island, and a dining area with round tables and chairs.
A spacious living area with a fireplace, comfortable seating, and large windows offering views.
A multi-story hotel with a parking lot, a swimming pool, and a landscaped area.

16. Residence Inn by Marriott Tampa Wesley Chapel

Residence Inn by Marriott Tampa Wesley Chapel
Wesley Chapel
United States
Jacquelyn
£98
includes taxes & fees
23 Sept - 24 Sept
Residence Inn by Marriott Tampa Wesley Chapel
A modern lobby with brick walls, a large window, and blue chairs around a small table.
A modern lobby with a reception desk, seating area, and a large window.
A spacious indoor dining area with multiple tables and chairs, large windows offering a view of the outdoors, and a flat-screen TV mounted on the wall.
A modern hotel lobby with a dining area, seating arrangements, and a large window providing natural light.

17. Hyatt Place Tampa/Wesley Chapel

Hyatt Place Tampa/Wesley Chapel
Lutz
United States
Roberta
£91
includes taxes & fees
27 Sept - 28 Sept
Hyatt Place Tampa/Wesley Chapel
A hotel lobby with a reception desk, seating area, and a kitchen.
A hotel room with a beige armchair, a blue sofa with cushions, a desk with a chair, and two wall-mounted lamps.
A lobby with a reception desk, a coffee station, and seating areas.
A hotel room with a desk, chair, minibar, television, and a patterned carpet.

18. Quality Inn & Suites Brooksville I-75/Dade City

Quality Inn & Suites Brooksville I-75/Dade City
Brooksville
United States
Miriam
£52
includes taxes & fees
30 Sept - 1 Oct
Quality Inn & Suites Brooksville I-75/Dade City
A multi-story hotel with a prominent logo, a central entrance, and a parking lot with several cars.
A modern living room with a wooden dining table, grey chairs, a grey sofa, and a green ottoman.
A gym with treadmills, a bench press, and a TV on the wall.
A hotel room with a bed, bedside table, lamp, and a TV on a stand.

19. WoodSpring Suites Wesley Chapel-Tampa

WoodSpring Suites Wesley Chapel-Tampa
Wesley Chapel
United States
Juan
£61
includes taxes & fees
13 Sept - 14 Sept
WoodSpring Suites Wesley Chapel-Tampa
A modern bar area with a long counter, multiple stools, and a variety of bottles and glasses.
A modern dining area with wooden tables and chairs, equipped with white tableware and a central light fixture.
A spacious living area with large windows, a sofa, a chair, and a table.
A snack display area with various chips and snacks.

20. Hilton Garden Inn Tampa-Wesley Chapel, FL

Hilton Garden Inn Tampa-Wesley Chapel, FL
Wesley Chapel
United States
Betsy
£91
includes taxes & fees
27 Sept - 28 Sept
Hilton Garden Inn Tampa-Wesley Chapel, FL
View all properties
Save an average of 15% on thousands of hotels when you're signed in

Learn more about San Antonio

Venture to Mirada Lagoon and Wesley Chapel District Park—just two of the sights around San Antonio.

See all hotels in San Antonio
A staircase with colorful tiles leading up to a wall with a sign reading "La Villita, Little Village of San Antonio".

Top San Antonio Hotel Reviews

Roadstar Hotel Zephyrhills

Roadstar Hotel Zephyrhills

8/10 Good
"All"
Ramón 2-night trip
Posted 2 hours ago
Roadstar Hotel Zephyrhills
Holiday Inn Express & Suites Tampa North - Wesley Chapel by IHG

Holiday Inn Express & Suites Tampa North - Wesley Chapel by IHG

10/10 Excellent
"Great Hotel, reasonable price,,,"
Nilsa 3-night trip
Posted 2 hours ago
Holiday Inn Express & Suites Tampa North - Wesley Chapel by IHG
Quality Inn Zephyrhills-dade City

Quality Inn Zephyrhills-dade City

10/10 Excellent
"I stay here every week. And it's hassle, free, no problems"
John 1-night trip
Posted 6 hours ago
Quality Inn Zephyrhills-dade City
Best Western Wesley Chapel

Best Western Wesley Chapel

8/10 Good
"Friendly staff"
Leopoldo 6-night trip
Posted 13 hours ago
Best Western Wesley Chapel
Days Inn by Wyndham Brooksville/Dade City

Days Inn by Wyndham Brooksville/Dade City

10/10 Excellent
"Always good and always amazing people here"
James 1-night trip
Posted 1 day ago
Days Inn by Wyndham Brooksville/Dade City
Hyatt Place Tampa/Wesley Chapel

Hyatt Place Tampa/Wesley Chapel

10/10 Excellent
"There was some signs of wear but the hotel is exceptionally clean. Staff very helpful"
Kathy 1-night trip
Posted 1 day ago
Hyatt Place Tampa/Wesley Chapel
Saddlebrook Resort

Saddlebrook Resort

10/10 Excellent
"Our stay was wonderful. We’re in Florida and extended our trip for the drive through safari. When we arrived at Saddlebrook we felt right at home. The staff was absolutely amazing. I met some awesome guests, as well. We did leave the following day though nothing at fault to the resort however, it truly is only to relax. There’s not much to do other than swim. I wish the best for this place. Any negative review is coming from someone who doesn’t know how to be polite to others or wanted to be pampered like the Ritz. When I called, they came. They were overly pleasant & helpful and most importantly, my kids were super safe there. If you want somewhere the adults can relax and let the kids play while you lay on a beach chair and no one is around you, this is your place! Your kids need to be able to pkay by themselves though."
Tilaye 1-night trip
Posted 1 day ago
Saddlebrook Resort
SpringHill Suites by Marriott Tampa North/I 75 Tampa Palms

SpringHill Suites by Marriott Tampa North/I 75 Tampa Palms

8/10 Good
"The front desk person who did the check-in was great! I saw him solve 3 issues with knowledge, a great attitude, and timely efficiency. He was very friendly and polite to every guest. Excellent customer service!"
Sonia 1-night trip
Posted 2 days ago
SpringHill Suites by Marriott Tampa North/I 75 Tampa Palms
Hampton Inn Dade City - Zephyrhills

Hampton Inn Dade City - Zephyrhills

10/10 Excellent
"Breakfast was good!"
Jeannie 1-night trip
Posted 6 days ago
Hampton Inn Dade City - Zephyrhills

More cheap stays in San Antonio

Extended Stay America Select Suites - Tampa - Northeast

Extended Stay America Select Suites - Tampa - Northeast

12162 Morris Bridge Rd Tampa FL
£54
15 Sept - 16 Sept
includes taxes & fees
Extended Stay America Select Suites - Tampa - Northeast
Quality Inn Zephyrhills-dade City

Quality Inn Zephyrhills-dade City

6815 Gall Blvd Zephyrhills FL
£58
20 Sept - 21 Sept
includes taxes & fees
7.8/10 Good! (1,009 reviews)
Quality Inn Zephyrhills-dade City
Days Inn by Wyndham Brooksville/Dade City

Days Inn by Wyndham Brooksville/Dade City

6320 Windmere Rd Brooksville FL
£60
27 Sept - 28 Sept
includes taxes & fees
7.6/10 Good! (313 reviews)
Days Inn by Wyndham Brooksville/Dade City
Sleep Inn near Busch Gardens/USF

Sleep Inn near Busch Gardens/USF

12282 Morris Bridge Rd Tampa FL
£61
16 Sept - 17 Sept
includes taxes & fees
Sleep Inn near Busch Gardens/USF
WoodSpring Suites Wesley Chapel-Tampa

WoodSpring Suites Wesley Chapel-Tampa

2800 Cypress Ridge Boulevard Wesley Chapel FL
£61
13 Sept - 14 Sept
includes taxes & fees
7.4/10 Good! (1,009 reviews)
WoodSpring Suites Wesley Chapel-Tampa
Hampton Inn Dade City - Zephyrhills

Hampton Inn Dade City - Zephyrhills

13215 Us Highway 301 Dade City FL
£81
20 Sept - 21 Sept
includes taxes & fees
8.8/10 Excellent! (936 reviews)
Hampton Inn Dade City - Zephyrhills

Frequently asked questions

What is the best area to stay in San Antonio?
The best area to stay in San Antonio, Florida, is generally around the town centre, particularly near State Road 52.This area offers convenient access to local amenities and the main routes for exploring the surrounding region. You'll find a few local shops and eateries here, giving you a sense of the community.For travellers looking for a quiet retreat with easy access to nature and local charm, this central area is ideal.
When is the best time to go to San Antonio?
The best time to visit San Antonio, Florida, is typically during the cooler, drier months from November to April.During these months, you'll experience pleasant temperatures, generally ranging from the low 20s to mid-20s Celsius, with less humidity. This makes it ideal for enjoying outdoor activities, exploring the local nature trails, or visiting nearby attractions without the intense heat and humidity that characterises the summer months.Couples looking for a relaxing escape will find this period particularly appealing. The comfortable weather allows for leisurely strolls through the town, enjoying the local eateries, or taking a scenic drive through the surrounding countryside. It's also a good time for those interested in local events, as many festivals and markets are scheduled during this agreeable season.Families might also find these months ideal, especially if they plan to visit nearby theme parks or enjoy outdoor adventures.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in San Antonio.
How much is the nightly rate at a San Antonio hotel?
Prices for hotels in San Antonio often vary, but you can find a great deal from £52 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

Explore a world of travel with Expedia