Title: TOP Panama Canal Zone Spa Hotels for 2025 - Spas in Panama Canal Zone | Expedia.co.uk [Panama Canal Zone Travel Guide](https://expedia.co.uk/Panama-Canal-Zone.dx6222968)[Hotels in Panama Canal Zone](https://expedia.co.uk/Panama-Canal-Zone-Hotels.d6222968.Travel-Guide-Hotels)[Holiday Rentals in Panama Canal Zone](https://expedia.co.uk/Panama-Canal-Zone-Holiday-Rentals.d6222968.Travel-Guide-HolidayRentals)[Flights to Panama Canal Zone](https://expedia.co.uk/Cheap-Flights-To-Panama-Canal-Zone.d6222968.Travel-Guide-Flights)[Panama Canal Zone Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Panama-Canal-Zone.d6222968.Car-Hire-Guide)[Panama Canal Zone Holidays](https://expedia.co.uk/Panama-Canal-Zone.d6222968.Holidays-City-Breaks) ![Colon showing building ruins and a park](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/267000/267275-Colon.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Spa Hotels in Panama Canal Zone - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Panama Canal Zone Spa Hotels Tonight [3 Nov - 4 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6222968&startDate=2025-11-03&endDate=2025-11-04&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [4 Nov - 5 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6222968&startDate=2025-11-04&endDate=2025-11-05&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [7 Nov - 9 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6222968&startDate=2025-11-07&endDate=2025-11-09&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [14 Nov - 16 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6222968&startDate=2025-11-14&endDate=2025-11-16&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Panama Canal Zone Spa Hotels ![Couples treatment room(s), Turkish bath/hammam, body treatments](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/46a37de3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/b883cd02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 6 AM to 8 PM, pool loungers](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/de56591c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/e77a4c37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Radisson Colon 2,000 Hotel & Casino Barrio Sur 8.2/10 Very good (800) "Everything was great good service and everything clean " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Zulema £73 includes taxes & fees 16 Nov - 17 Nov [](https://www.expedia.co.uk/Colon-Hotels-Radisson-Colon-2.h2147349.Hotel-Information) ![Sports massages, massages](https://images.trvl-media.com/lodging/67000000/66730000/66723000/66722954/4d4be0f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/67000000/66730000/66723000/66722954/4502bc4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/67000000/66730000/66723000/66722954/ac5d93a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 9:30 AM to 7:00 PM, pool loungers](https://images.trvl-media.com/lodging/67000000/66730000/66723000/66722954/84f0a319.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SAND DIAMOND HOTEL Colon 8.4/10 Very good (198) "Great staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robert LahMar £100 includes taxes & fees 6 Nov - 7 Nov [](https://www.expedia.co.uk/Colon-Hotels-SAND-DIAMOND-HOTEL.h66722954.Hotel-Information) ![Couples treatment room(s), sauna, hot tub, steam room, body treatments](https://images.trvl-media.com/lodging/13000000/12450000/12445600/12445554/9086aeb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 outdoor pools, open 8:00 AM to 8:00 PM, free pool cabanas](https://images.trvl-media.com/lodging/13000000/12450000/12445600/12445554/7c338453.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/13000000/12450000/12445600/12445554/f13ec34b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Local and international cuisine](https://images.trvl-media.com/lodging/13000000/12450000/12445600/12445554/818dd731.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Dreams Playa Bonita Panama - All Inclusive Veracruz 7.4/10 Good (1002) "It is a nice place for family time" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Julián Andrés £207 includes taxes & fees 3 Dec - 4 Dec [](https://www.expedia.co.uk/Panama-City-Hotels-Dreams-Playa-Bonita-Panama.h12445554.Hotel-Information) ![Couples treatment room(s), steam room, Turkish bath/hammam](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/ff18df89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/e5856e04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom, Non Smoking, Golf View (Terrace) | Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/d80494b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/2a51fa85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City Juan Diaz 9.6/10 Exceptional (621) "great service" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gianluca £172 includes taxes & fees 23 Nov - 24 Nov [](https://www.expedia.co.uk/Panama-City-Hotels-The-Santa-Maria.h20958573.Hotel-Information) ![Couples treatment room(s), sauna, steam room, body treatments](https://images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/da95ec78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, 2 poolside bars, swim-up bar](https://images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/a12fa485.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 outdoor pools, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/6d441b5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private beach, sun-loungers, beach umbrellas, beach towels](https://images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/e679a1c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Westin Playa Bonita Panama Veracruz 8.0/10 Very good (1007) "Had a great stay! The room was clean, comfortable, and exactly what we needed. The staff was super friendly and helpful, and the location was perfect. Everything went smoothly from check-in to check-out — would definitely stay here again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Olsaris £146 includes taxes & fees 16 Nov - 17 Nov [](https://www.expedia.co.uk/Panama-City-Hotels-The-Westin-Playa-Bonita-Panama.h4668643.Hotel-Information) ![Outdoor pool, open 7:00 AM to 10:30 PM, free pool cabanas](https://images.trvl-media.com/lodging/1000000/30000/26300/26240/b7e843b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Poolside bar](https://images.trvl-media.com/lodging/1000000/30000/26300/26240/d73825f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/30000/26300/26240/ea26a97c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sports facility](https://images.trvl-media.com/lodging/1000000/30000/26300/26240/04f50e95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Riande Aeropuerto Hotel & Casino Tocumen 8.6/10 Excellent (1892) "Property location is great for the airport" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Amber £144 includes taxes & fees 4 Nov - 5 Nov [](https://www.expedia.co.uk/Tocumen-Hotels-Riande-Aeropuerto-Hotel-Casino.h26240.Hotel-Information) ![Couples treatment room(s), sauna, hot tub, Turkish bath/hammam](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/57cdf539.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/25adc131.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 restaurants, breakfast served](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/1f8c9ffe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/179e52b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sheraton Grand Panama San Francisco 8.6/10 Excellent (972) "Centrally located and friendly staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Julio £112 includes taxes & fees 9 Nov - 10 Nov [](https://www.expedia.co.uk/Panama-City-Hotels-Sheraton-Grand-Panama.h1161.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/112000000/111850000/111843300/111843270/w3836h2557x4y3-88d79c27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/112000000/111850000/111843300/111843270/w3837h2560x3y0-f3c8f26d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/112000000/111850000/111843300/111843270/w3837h2557x3y3-241f7e7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/112000000/111850000/111843300/111843270/a14c580c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Regency Panama City Bella Vista 10/10 Exceptional (90) "Great stay for a birthday celebration " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carmenzina £125 includes taxes & fees 7 Nov - 8 Nov [](https://www.expedia.co.uk/Panama-City-Hotels-Hyatt-Regency-Panama-City.h111843270.Hotel-Information) ![Hot tub, body treatments, aromatherapy, hot stone massages](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/c754d1cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch, dinner served; French cuisine ](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/246e2668.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sports facility](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/cf22e531.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/a7b599bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Waldorf Astoria Panama Bella Vista 9.0/10 Wonderful (1001) "Great experience overall! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Reginald £145 includes taxes & fees 1 Dec - 2 Dec [](https://www.expedia.co.uk/Panama-City-Hotels-Waldorf-Astoria-Panama.h4952056.Hotel-Information) ![Couples treatment room(s), sauna, hot tub, steam room](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/59f34bde.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/bc945d5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 7:00 AM to 10:00 PM, free pool cabanas](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/ae55473e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/4aee4896.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Megapolis Hotel Panamá San Francisco 8.4/10 Very good (1174) "Great stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mark £102 includes taxes & fees 9 Nov - 10 Nov [](https://www.expedia.co.uk/Panama-City-Hotels-Megapolis-Hotel-Panama.h91995575.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-11-17&endDate=2025-11-18®ionId=6222968&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Find out more about Panama Canal Zone ### Top Panama Canal Zone attractions for a relaxing vacation The Panama Canal Zone is not only a marvel of engineering but also a gateway to exquisite relaxation and leisure for those seeking spa hotels. Begin your journey by exploring the Miraflores Locks, where you can witness massive ships navigating through the canal while enjoying a serene spa treatment with views of the waterway. Next, immerse yourself in the lush beauty of Soberanía National Park, offering stunning hiking trails and birdwatching opportunities, perfect for adventurous families looking to reconnect with nature before retreating to their spa haven. Don't miss the historic Panama Canal Museum in Balboa, which provides fascinating insights into the canal's history and its impact on global trade, setting a captivating context for your stay. For a unique experience, consider visiting the Biomuseo, a stunning architectural gem that highlights Panama's biodiversity, allowing you to enjoy nature's wonders and then unwind with a soothing massage at your hotel. The vibrant neighbourhood of Amador Causeway is also worth exploring; its scenic waterfront offers restaurants and shops alongside breathtaking views of the city skyline, making it an excellent base for your spa hotel experience. Here, you can indulge in luxurious spa services after a day of adventure, ensuring that both relaxation and excitement intertwine seamlessly in your Panama Canal Zone experience. ## Top Panama Canal Zone Hotel Reviews ![JW Marriott Panama](//images.trvl-media.com/lodging/5000000/4110000/4109200/4109123/fb42dbf6_y.jpg) ### JW Marriott Panama 10/10 Excellent "Yea bar was well stocked " [](https://expedia.co.uk/Panama-City-Hotels-JW-Marriott-Panama.h4109123.Hotel-Information) ![Sheraton Grand Panama](//images.trvl-media.com/lodging/1000000/10000/1200/1161/179e52b4_y.jpg) ### Sheraton Grand Panama 10/10 Excellent "Clean room and helpful staff. " [](https://expedia.co.uk/Panama-City-Hotels-Sheraton-Grand-Panama.h1161.Hotel-Information) ![Central Hotel Panama Casco Viejo](//images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/3165768f_y.jpg) ### Central Hotel Panama Casco Viejo 10/10 Excellent "Staffs were wonderful." [](https://expedia.co.uk/Panama-City-Hotels-Central-Hotel-Panama-Casco-Viejo.h15683502.Hotel-Information) ![The Westin Playa Bonita Panama](//images.trvl-media.com/lodging/5000000/4670000/4668700/4668643/f767a768_y.jpg) ### The Westin Playa Bonita Panama 10/10 Excellent "We had an amazing family vacation. Especial mention for very exceptional people such as Franklin who is the best taxi driver and tour guy that you can get and Maria, who provides a personalized customer service in the buffet. They made our vacation unforgettable. They definitely upgrade any experience. " [](https://expedia.co.uk/Panama-City-Hotels-The-Westin-Playa-Bonita-Panama.h4668643.Hotel-Information) ![Hotel Riu Plaza Panama](//images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg) ### Hotel Riu Plaza Panama 10/10 Excellent "The place was clean n always fresh , definitely my place to go whenever I come back to Panama. Love every bit of my stay " [](https://expedia.co.uk/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) ![Radisson Hotel Panama Canal](//images.trvl-media.com/lodging/1000000/810000/809200/809149/23e8ad44_y.jpg) ### Radisson Hotel Panama Canal 10/10 Excellent "Superb customer service Ivonne Carrasco " [](https://expedia.co.uk/Amador-Hotels-Radisson-Hotel-Panama-Canal.h809149.Hotel-Information) ![Waldorf Astoria Panama](//images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/e7e98c5e_y.jpg) ### Waldorf Astoria Panama 10/10 Excellent "Upon arrival to the Waldorf, Edgar was right there to assist us with our luggage to the room. It was at that moment I knew the W.A. hospitality was about to be extraordinary. " [](https://expedia.co.uk/Panama-City-Hotels-Waldorf-Astoria-Panama.h4952056.Hotel-Information) ![Dreams Playa Bonita Panama - All Inclusive](//images.trvl-media.com/lodging/13000000/12450000/12445600/12445554/7c338453_y.jpg) ### Dreams Playa Bonita Panama - All Inclusive 10/10 Excellent "Staff was nice but not in any hurry" [](https://expedia.co.uk/Panama-City-Hotels-Dreams-Playa-Bonita-Panama.h12445554.Hotel-Information)