Panama Canal Zone Holidays from £580

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Your Panama Canal Zone Holiday

When you're ready to embark on your next great escape, a holiday package to Panama Canal Zone awaits. Immerse yourself in the beauty and charm of this destination where you can experience its historical landmarks, tropical climate, spectacular views and more. Your trip to Panama Canal Zone wouldn't be complete without exploring some of its most well-known cities, starting with Ancon. A couple of the top attractions here include Albrook Shopping Mall and Cinta Costera. Colon is another favourite city with Panama Canal Zone travellers. Visitors to this exciting city enjoy Limon Bay and Fort San Lorenzo. Expedia is your one-stop shop when it comes to planning your Panama Canal Zone holiday. From accommodation and flights, to activities and rental cars, we're here to help you curate a travel experience like no other.

Top Panama Canal Zone Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
Hotel Casa Panamá
Mahogany Suites
Hotel Plaza Herrera
Hotel La Compania, in the Unbound Collection by Hyatt
Casa Mallet by Wynwood House

Where to stay in Panama Canal Zone

Find the best Panama Canal Zone areas and neighborhoods for the activities you enjoy most. Learn more about Panama Canal Zone

Panama Canal Zone Essential Information

Language
Spanish
Currency
Panamanian balboas
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Tocumen Intl. Airport (PTY)

Top hotels in Panama Canal Zone

Marriott Panama Hotel

Marriott Panama Hotel

4 out of 5
Roosevelt Ave., Allbrook Mall, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is £122 per night from 13 Sept to 14 Sept
£122
13 Sept - 14 Sept
includes taxes & fees
Marriott Panama Hotel
Radisson Hotel Panama Canal

Radisson Hotel Panama Canal

4.5 out of 5
Amador Avenue & Van Hook Street, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is £71 per night from 27 Sept to 28 Sept
£71
27 Sept - 28 Sept
includes taxes & fees
8.4/10 Very Good! (1,001 reviews)
"Love the Friday's restaurant. Easy parking, and easy access to Amador and the bridge of America"

Reviewed on 17 Aug 2025

Radisson Hotel Panama Canal
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is £82 per night from 31 Aug to 1 Sept
£82
31 Aug - 1 Sept
includes taxes & fees
9/10 Wonderful! (4,208 reviews)
"The location was amazing and hotel was amazing however I was very disappointed that the pool was closed for our entire trip."

Reviewed on 26 Aug 2025

Hotel Riu Plaza Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.