Panama Canal Zone Holidays from £753

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Your Panama Canal Zone Holiday

When you're ready to embark on your next great escape, a holiday package to Panama Canal Zone awaits. Immerse yourself in the beauty and charm of this destination where you can experience its historical landmarks, tropical climate, spectacular views and more. Your trip to Panama Canal Zone wouldn't be complete without exploring some of its most well-known cities, starting with Ancon. A couple of the top attractions here include Albrook Shopping Mall and Cinta Costera. Colon is another favourite city with Panama Canal Zone travellers. Visitors to this exciting city enjoy Limon Bay and Fort San Lorenzo. Expedia is your one-stop shop when it comes to planning your Panama Canal Zone holiday. From accommodation and flights, to activities and rental cars, we're here to help you curate a travel experience like no other.

Top Panama Canal Zone Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
Dovle Residences by HMS-Preferred Member
Megapolis Hotel Panamá
Las Americas Golden Tower Panama
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Riande Aeropuerto Hotel & Casino

Where to stay in Panama Canal Zone

Find the best Panama Canal Zone areas and neighborhoods for the activities you enjoy most. Learn more about Panama Canal Zone

Panama Canal Zone Essential Information

Language
Spanish
Currency
Panamanian balboas
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Tocumen Intl. Airport (PTY)

Top hotels in Panama Canal Zone

Marriott Panama Hotel

Marriott Panama Hotel

4 out of 5
Roosevelt Ave., Allbrook Mall Panama City Panama
Fully refundableReserve now, pay when you stay
The price is £131 per night from 25 Apr to 26 Apr
£131
25 Apr - 26 Apr
includes taxes & fees
9/10 Wonderful! (1,013 reviews)
This hotel is attached to the largest mall in Central America. Amazing number of places to shop and eat (not much to walk to outside of the mall, but metro is close and Ubers are cheap.) Staff is really friendly and helpful. Great breakfast.

Reviewed on 12 Apr 2026

Marriott Panama Hotel
Radisson Hotel Panama Canal

Radisson Hotel Panama Canal

4.5 out of 5
Amador Avenue & Van Hook Street Panama City Panama
Fully refundable
The price is £66 per night from 10 May to 11 May
£66
10 May - 11 May
includes taxes & fees
8.6/10 Excellent! (1,026 reviews)
Breakfast buffet was amazing. So much selection and the staff were very attentive. The pool was amazing and the view of the bay was so cool!

Reviewed on 13 Apr 2026

Radisson Hotel Panama Canal
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
Fully refundableReserve now, pay when you stay
The price is £118 per night from 5 May to 6 May
£118
5 May - 6 May
includes taxes & fees
9/10 Wonderful! (5,306 reviews)
Everything was great rooms clean very staff and breakfast was awesome

Reviewed on 13 Apr 2026

Hotel Riu Plaza Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Frequently asked questions

Can I cancel my flight booking to Panama Canal Zone due to COVID-19?
Our helpful Customer Service Portal is your one-stop shop for most travel queries, including about flight changes and cancellations related to COVID-19. For greater peace of mind, look over the terms and conditions of your airfare before booking your tickets.
What's the best way to find cheap flights to Panama Canal Zone that have flexible change policies?
When it comes to travelling these days, flexibility is a must. That's why we have a "No change fee" search function to help you track down cheap, flexible fares to Panama Canal Zone. It's on the left-hand side of your screen underneath the "Flexible change policies" subheading.
What are some of the general tips for travellers to Panama Canal Zone during the COVID-19 outbreak?
With the continued impacts of the COVID-19 pandemic, travelling today comes with more challenges. Have a read over these valuable tips before jumping on your plane to Panama Canal Zone:
  • Know what rules and restrictions apply to both your destination and origin. It may not be possible to travel depending on local circumstances, so be sure to check in advance.
  • When you go through airport screening, do not remove your face mask. You will be required to lower it briefly to verify your identity. Anyone refusing to wear a face mask may face civil penalties and may also be escorted from the terminal.
  • To reduce the likelihood of cross-contamination, position your boarding pass on the reader yourself and then hold it up for inspection. Do not hand your boarding pass directly to a TSA officer.
  • One liquid hand sanitizer container is now permitted in your carry-on bag. It must be no larger than 12 oz (350 ml), and you'll need to remove it from your bag at the X-ray machine for scanning.
  • To minimize handling during screening, place items such as your wallet, phone and belt into your carry-on rather than into the bins.
  • If you're planning to take food through the security checkpoint, put it in a clear plastic bag and then into a screening bin. This lessens the likelihood that a TSA officer will need to touch your carry-on bag or food container for inspection.

Which airlines fly to Panama Canal Zone?
Copa Airlines is a top air carrier servicing Panama Canal Zone. Search for a fare to Tocumen Intl. Airport (PTY) and you'll have 3173 Copa Airlines flights every month to pick from.
How can I find cheap tickets to Panama Canal Zone?
In the last seven days, was the best price for a flight to Panama Canal Zone. For an even cheaper fare, book in advance and be flexible with your dates. Search for your airfare to Panama Canal Zone, then check out prices for similar time frames by clicking on the "flexible dates" link above.
How much is a flight to Panama Canal Zone?
In the last seven days, return tickets to Panama Canal Zone sold for as low as and reached a maximum of . For one-way journeys departing from (), the lowest amount paid during this time was .
What are the most popular airports to fly into in Panama Canal Zone?
Jet into Tocumen Intl. Airport (PTY) and sample the best that Panama Canal Zone has to offer. As the region's primary entry point, roughly 3507 flights touch down here every month.
When is the cheapest time to fly to Panama Canal Zone?
If you're not fixed on your travel dates to Panama Canal Zone, leave early in the week. The most affordable day to take off is normally Tuesday, followed by Monday. Saturday is typically the most expensive day, with lots of holiday makers choosing to take off on the weekend.
How much is a plane ticket to Panama Canal Zone?
In the last seven days, plane tickets to Panama Canal Zone ranged from to .
Which airlines with flights to Panama Canal Zone employ COVID-19 cleanliness policies?
As passengers and cabin crew start travelling again, nearly all airlines have introduced social distancing and other necessary actions to reduce the spread of COVID-19. Here are just some of them:
  • Copa Airlines - this airline is known for conducting passenger temperature checks and electrostatic cleaning.
  • United Airlines - this airline is known for providing passenger masks and cleaning with disinfectant.
  • American Airlines - this airline is known for providing passenger masks and cleaning with disinfectant.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.