Panama Canal Zone Holidays from £558

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to £750 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Packages with flights are ATOL protected

Your Panama Canal Zone Holiday

When you're ready to embark on your next great escape, a holiday package to Panama Canal Zone awaits. Immerse yourself in the beauty and charm of this destination where you can experience its historical landmarks, tropical climate, spectacular views and more. Your trip to Panama Canal Zone wouldn't be complete without exploring some of its most well-known cities, starting with Ancon. A couple of the top attractions here include Albrook Shopping Mall and Cinta Costera. Colon is another favourite city with Panama Canal Zone travellers. Visitors to this exciting city enjoy Limon Bay and Fort San Lorenzo. Expedia is your one-stop shop when it comes to planning your Panama Canal Zone holiday. From accommodation and flights, to activities and rental cars, we're here to help you curate a travel experience like no other.

Top Panama Canal Zone Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
Riande Aeropuerto Hotel & Casino
Central Hotel Panama Casco Viejo
Megapolis Hotel Panamá
Las Americas Golden Tower Panama
Las Clementinas

Where to stay in Panama Canal Zone

Find the best Panama Canal Zone areas and neighborhoods for the activities you enjoy most. Learn more about Panama Canal Zone

Panama Canal Zone Essential Information

Language
Spanish
Currency
Panamanian balboas
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Tocumen Intl. Airport (PTY)

Top hotels in Panama Canal Zone

Radisson Hotel Panama Canal

Radisson Hotel Panama Canal

4.5 out of 5
Amador Avenue & Van Hook Street Panama City Panama
Fully refundable
The price is £73 per night from 21 Jul to 22 Jul
£73
21 Jul - 22 Jul
includes taxes & fees
8.6/10 Excellent! (1,009 reviews)
"It wasn't a horrible stay but I wouldn't stay there again. I'll start with the negatives and finish with the positives. -s The hotel is very dated and looks like it. The sink in my room drained very slowly and the faucet in the tu dropped continuosly. Many of the outlets didn't work. But in all fairness ..."

Reviewed on 11 Jul 2026

Radisson Hotel Panama Canal
Marriott Panama Hotel

Marriott Panama Hotel

4 out of 5
Roosevelt Ave., Allbrook Mall Panama City Panama
Fully refundableReserve now, pay when you stay
The price is £132 per night from 25 Jul to 26 Jul
£132
25 Jul - 26 Jul
includes taxes & fees
9/10 Wonderful! (1,005 reviews)
"The room was clean, the staff was nice and the breakfast had gluten free options, the gf bread was great and a really good buffet."

Reviewed on 13 Jul 2026

Marriott Panama Hotel
Summit Rainforest Golf Resort & All Inclusive

Summit Rainforest Golf Resort & All Inclusive

4 out of 5
Omar Torrijos Ave Panama City Panama
Fully refundableReserve now, pay when you stay
The price is £175 per night from 16 Jul to 17 Jul
£175
16 Jul - 17 Jul
includes taxes & fees
8.4/10 Very good! (1,004 reviews)
"No había toallas y despues de 3 horas del check in tuvo mi esposo que bajar a buscarlas al Lobby. Lo más incomodo fue que no nos creían como si uno fuera ignorante y ko haya viajado antes. Creo que deben mejorar las instalaciones, se ven muy viejas y es un destino interesante pero muy feas las ..."

Reviewed on 12 Jul 2026

Summit Rainforest Golf Resort & All Inclusive
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Panama Canal Zone attractions

Frequently asked questions

Why should I book my Panama Canal Zone holiday with Expedia?
With top-value flights, accommodation and car hire choices all in the same place, Expedia makes booking your Panama Canal Zone adventure hassle-free. Plus, we can help you bundle your bookings into a package holiday so you can enjoy even more savings. Select from fabulous stays, add your flights and/or a car hire (and maybe even some fun tours and activities!) and land unbeatable prices. Need to cancel? Expedia has a flexible cancellation policy for many reservations. To find out more, visit our Customer Service Portal link.
When is the best time of year to holiday in Panama Canal Zone?
Panama Canal Zone draws the crowds in March, April and May. If you want a more laid-back getaway, head there in August, September and December. With average daytime temperatures of 26ºC, January is the coolest period in Panama Canal Zone. The warmest time of year is April, when you can experience average temperatures of 28ºC throughout the day. Whatever the weather conditions, you'll find plenty to keep you occupied here.
What are the top hotels for my holiday in Panama Canal Zone?
If you'd like to stay in the Barrio Norte neighbourhood, Melia Panama Canal and Radisson Colon 2,000 Hotel & Casino are fabulous options. Barrio Sur is also a popular Panama Canal Zone area. We recommend Gamboa Rainforest Reserve or New Washington Hotel if you choose this end of town.
How do I get a cheap holiday to Panama Canal Zone?
Secure flights that fit your schedule, add a hotel to your booking and watch the savings stack up with a Panama Canal Zone holiday. It's that simple! From flights and hotels to tours and hire cars, Expedia is where your cheap getaway begins. And with more than 400 partner airlines and 321,000 hotels globally to pick from, you won't be short of choice. Learn more about how you can save money on your holiday when you combine your hotel and flight bookings with Expedia.
What should I do on my Panama Canal Zone holiday?
Make sure your holiday in Panama Canal Zone is one to remember by checking out its best attractions. Miraflores Locks, Gatun Locks, Albrook Shopping Mall and Veracruz Beach are just some of the things worth discovering while you're in the city.
What is the best area to stay in when on holiday in Panama Canal Zone?
There's plenty to do in Panama Canal Zone, so stay near its top attractions and maximise your time sightseeing. Miraflores Locks is one place to put on your to-do list.
Do I need a visa for my Panama Canal Zone holiday?
Official government websites are the best source of information on visa requirements, application procedures and necessary documentation. Your nationality and reason for travelling, whether it be for tourism or work, will determine if you need a visa for Panama Canal Zone. Also be sure that your passport is up to date and has a minimum of six months validity remaining beyond your return date. Do all your travel planning well ahead of time to avoid any nasty last-minute surprises.
What should I wear on my Panama Canal Zone holiday?
Although everyone's fashion style differs, it can help to have some guidelines for what type of clothes to wear during your holiday in Panama Canal Zone. We recommend looking up style blogs before leaving for inspiration on fashion trends or dress codes. Daytime temperatures during January, Panama Canal Zone's coolest month, average around 26ºC. April marks this city's warmest month when the average daily temperature reaches 28ºC. Our top tip? Take the guesswork out of packing and check the local weather conditions.
What does an Expedia Panama Canal Zone holiday include?
Expedia has all you need to lock in your Panama Canal Zone getaway, but how you structure your package is up to you. Pick from a combination of flights, hire cars and hotels. In search of a few activities to keep you on the go? Once you've made your booking, you can add them too. Whatever your style or budget, there's a deal to match your needs. Apartments and private holiday homes are a few of the most highly sought-after property types in Panama Canal Zone. Whatever your preference or size of your group, you can rely on Expedia for the flexibility and freedom to customise your next dream escape.
Does Expedia offer Book Now, Pay Later Panama Canal Zone holidays?
Expedia has joined forces with online lender Klarna to make booking your next break easier on the purse strings. Paying by instalment means you can spread the costs of your next dream escape, leaving you with more money to play with while you're travelling. Klarna has several payment plans to choose from, so you're sure to find something that fits into your budget. Take a look at these flexible payment options:

  • Pay monthly holidays: Klarna offers payments in multiple transactions that work for all budget sizes, so you can escape on that well-deserved holiday sooner.
  • No-deposit holidays: When you see an awesome deal but don't have the full amount yet, Klarna's no-deposit holiday plan will allow you to Book Now, Pay Later to lock in your escape.

Can I choose my airline with a Panama Canal Zone Expedia holiday?
Yes — that's one of the best things about an Expedia package. You get to choose. We have more than 400 airline partners throughout the world, so you have options galore when arranging your Panama Canal Zone escape.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.