Title: TOP Business Hotels in Panama Canal Zone for 2026 | Expedia.co.uk [Panama Canal Zone Travel Guide](https://expedia.co.uk/Panama-Canal-Zone.dx6222968)[Hotels in Panama Canal Zone](https://expedia.co.uk/Panama-Canal-Zone-Hotels.d6222968.Travel-Guide-Hotels)[Holiday Rentals in Panama Canal Zone](https://expedia.co.uk/Panama-Canal-Zone-Holiday-Rentals.d6222968.Travel-Guide-HolidayRentals)[Flights to Panama Canal Zone](https://expedia.co.uk/Cheap-Flights-To-Panama-Canal-Zone.d6222968.Travel-Guide-Flights)[Panama Canal Zone Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Panama-Canal-Zone.d6222968.Car-Hire-Guide)[Panama Canal Zone Holidays](https://expedia.co.uk/Panama-Canal-Zone.d6222968.Holidays-City-Breaks) ![0_BU000512](https://images.trvl-media.com/place/6222968/089e46e9-cc78-4d6b-b43a-af08a95dd797.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6222968/089e46e9-cc78-4d6b-b43a-af08a95dd797.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Panama Canal Zone Business Hotels Tonight [24 Feb - 25 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=6222968&startDate=2026-02-24&endDate=2026-02-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [25 Feb - 26 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=6222968&startDate=2026-02-25&endDate=2026-02-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [27 Feb - 1 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6222968&startDate=2026-02-27&endDate=2026-03-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [6 Mar - 8 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6222968&startDate=2026-03-06&endDate=2026-03-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Panama Canal Zone business-friendly hotels ![Garden](https://images.trvl-media.com/lodging/1000000/810000/809200/809149/fe3d7092.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/810000/809200/809149/93c6a3dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/1000000/810000/809200/809149/dea447f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/1000000/810000/809200/809149/ae564df0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Radisson Hotel Panama Canal [](https://www.expedia.co.uk/Amador-Hotels-Radisson-Hotel-Panama-Canal.h809149.Hotel-Information) Amador 8.6/10 Excellent (1,009 reviews) "Unbeatable location if your visit is all about the Panama Canal. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Vitaliy £69 includes taxes & fees 24 Mar - 25 Mar [](https://www.expedia.co.uk/Amador-Hotels-Radisson-Hotel-Panama-Canal.h809149.Hotel-Information) ![Outdoor pool, open 7:00 AM to 8:00 PM, pool umbrellas](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/d26cb29b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/c617be5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/860def94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/7bb8f38a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Marriott Panama Hotel [](https://www.expedia.co.uk/Panama-City-Hotels-Marriott-Panama-Hotel.h6099287.Hotel-Information) Panama City 9.0/10 Wonderful (1,012 reviews) "Good room, good breakfast, friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Bret £124 includes taxes & fees 7 Mar - 8 Mar [](https://www.expedia.co.uk/Panama-City-Hotels-Marriott-Panama-Hotel.h6099287.Hotel-Information) ![2 outdoor pools, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/4000000/3010000/3006200/3006144/f0857b87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/4000000/3010000/3006200/3006144/c76ac3a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gazebo](https://images.trvl-media.com/lodging/4000000/3010000/3006200/3006144/d640f143.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/4000000/3010000/3006200/3006144/4608cf45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Summit Rainforest & Golf Resort [](https://www.expedia.co.uk/Ancon-Hotels-Summit-Rainforest-Golf-Resort.h3006144.Hotel-Information) Panama City 8.4/10 Very good (1,001 reviews) "Wonderful staff & property!! The breakfast, lunch & dinner meals were outstanding. Beautiful views! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Janice £76 includes taxes & fees 26 Feb - 27 Feb [](https://www.expedia.co.uk/Ancon-Hotels-Summit-Rainforest-Golf-Resort.h3006144.Hotel-Information) ![Poolside bar](https://images.trvl-media.com/lodging/1000000/440000/438200/438135/c696a538.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast served](https://images.trvl-media.com/lodging/1000000/440000/438200/438135/76d19433.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/440000/438200/438135/c7eb2b99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/440000/438200/438135/4b5df5ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Gamboa Rainforest Reserve [](https://www.expedia.co.uk/Gamboa-Hotels-Gamboa-Rainforest-Reserve.h438135.Hotel-Information) Colon 8.0/10 Very good (705 reviews) "Unique property with beautiful nature surrounding it. Staff are attentive and friendly and the Hotel has access to a lot of very unique activities. Good food as well." ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Kevin £110 includes taxes & fees 25 Feb - 26 Feb [](https://www.expedia.co.uk/Gamboa-Hotels-Gamboa-Rainforest-Reserve.h438135.Hotel-Information) ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/3000000/2100000/2096400/2096355/6785cd9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/3000000/2100000/2096400/2096355/cb8e7c14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Room, 2 Double Beds, Pool View | Premium bedding, in-room safe, desk, blackout curtains](https://images.trvl-media.com/lodging/3000000/2100000/2096400/2096355/be13d503.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/3000000/2100000/2096400/2096355/b2fe58e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Panama Canal by IHG [](https://www.expedia.co.uk/Panama-City-Hotels-Holiday-Inn-Panama-Canal.h2096355.Hotel-Information) Panama City 8.6/10 Excellent (456 reviews) "The staff was so cordial and nice " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sonny £74 includes taxes & fees 7 Mar - 8 Mar [](https://www.expedia.co.uk/Panama-City-Hotels-Holiday-Inn-Panama-Canal.h2096355.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/67000000/66730000/66723000/66722954/ac5d93a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 9:30 AM to 7:00 PM, pool loungers](https://images.trvl-media.com/lodging/67000000/66730000/66723000/66722954/4df4233d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/67000000/66730000/66723000/66722954/e5f9d9ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/67000000/66730000/66723000/66722954/e4736918.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SAND DIAMOND HOTEL [](https://www.expedia.co.uk/Colon-Hotels-SAND-DIAMOND-HOTEL.h66722954.Hotel-Information) Colon 8.6/10 Excellent (229 reviews) "Great hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) DIANA £97 includes taxes & fees 26 Feb - 27 Feb [](https://www.expedia.co.uk/Colon-Hotels-SAND-DIAMOND-HOTEL.h66722954.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/24000000/23810000/23809900/23809852/5cf5cc1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/24000000/23810000/23809900/23809852/14fa725b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/24000000/23810000/23809900/23809852/e9b037a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/24000000/23810000/23809900/23809852/ea00f846.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Cubana Hotel & Residencial [](https://www.expedia.co.uk/Colon-Hotels-La-Cubana-Hotel-Residencial.h23809852.Hotel-Information) Cristobal 8.2/10 Very good (116 reviews) "Easy access to colon libre zone" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Everal £24 includes taxes & fees 25 Feb - 26 Feb [](https://www.expedia.co.uk/Colon-Hotels-La-Cubana-Hotel-Residencial.h23809852.Hotel-Information) ![Beach/ocean view](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/665077af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gym](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/1a303895.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/53f67005.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/402ceb06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Radisson Colon 2,000 Hotel & Casino [](https://www.expedia.co.uk/Colon-Hotels-Radisson-Colon-2.h2147349.Hotel-Information) Barrio Sur 8.2/10 Very good (870 reviews) "Staff was very friendly and accommodating. I really enjoyed the breakfast." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Helene £89 includes taxes & fees 13 Mar - 14 Mar [](https://www.expedia.co.uk/Colon-Hotels-Radisson-Colon-2.h2147349.Hotel-Information) ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/877d081d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/757e8465.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/2f37bae5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/8103ef2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Crowne Plaza Panama Airport by IHG [](https://www.expedia.co.uk/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information) Tocumen 8.6/10 Excellent (2,453 reviews) "Very friendly staff, impeccable room, free airport shuttle, nice food..... we had a great stay!" ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Renildis £97 includes taxes & fees 6 Mar - 7 Mar [](https://www.expedia.co.uk/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information) ![Outdoor pool, open 7:00 AM to 10:30 PM, free pool cabanas](https://images.trvl-media.com/lodging/1000000/30000/26300/26240/b7e843b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Poolside views, serves lunch and dinner](https://images.trvl-media.com/lodging/1000000/30000/26300/26240/700fef33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Poolside views, serves lunch and dinner](https://images.trvl-media.com/lodging/1000000/30000/26300/26240/88cca748.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/1000000/30000/26300/26240/dc6a5657.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Riande Aeropuerto Hotel & Casino [](https://www.expedia.co.uk/Tocumen-Hotels-Riande-Aeropuerto-Hotel-Casino.h26240.Hotel-Information) Tocumen 8.4/10 Very good (1,860 reviews) "Very nice staff and confortable stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) MARIA £102 includes taxes & fees 3 Mar - 4 Mar [](https://www.expedia.co.uk/Tocumen-Hotels-Riande-Aeropuerto-Hotel-Casino.h26240.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-03-10&endDate=2026-03-11®ionId=6222968&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-uk-fr-de.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Holiday Sale Members save up to 40% on hotels and holiday homes. Plan this year’s big trip and save. [Book now](https://expedia.co.uk/cheap-deals?rfrr=AFFINITY_SPRING_PROMO_6222968) ## Top Panama Canal Zone Hotel Reviews ![The Executive Hotel](https://images.trvl-media.com/lodging/1000000/530000/522100/522086/493046b7_y.jpg) ### The Executive Hotel 10/10 Excellent "Everything was perfect" [](https://expedia.co.uk/Panama-City-Hotels-The-Executive-Hotel.h522086.Hotel-Information) ![Crowne Plaza Panama Airport by IHG](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/877d081d_y.jpg) ### Crowne Plaza Panama Airport by IHG 10/10 Excellent "It’s right by the airport and the shuttle was right on time. Perfect for an overnight connecting flight. " [](https://expedia.co.uk/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information) ![Waldorf Astoria Panama](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/e7e98c5e_y.jpg) ### Waldorf Astoria Panama 10/10 Excellent "The hotel was wonderful. The entire hotel was clean, staff welcoming especially security employee Flash. The breakfast buffet was great and it was so nice that Divney the receptionist remembered our names each day. My overall stay was great and I would highly recommend this hotel to anyone visiting Panama. " [](https://expedia.co.uk/Panama-City-Hotels-Waldorf-Astoria-Panama.h4952056.Hotel-Information) ![Marriott Panama Hotel](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/b61be540_y.jpg) ### Marriott Panama Hotel 10/10 Excellent "Really nice and great breakfast" [](https://expedia.co.uk/Panama-City-Hotels-Marriott-Panama-Hotel.h6099287.Hotel-Information) ![Principe Hotel and Suites](https://images.trvl-media.com/lodging/8000000/7460000/7451800/7451703/2baee2b4_y.jpg) ### Principe Hotel and Suites 10/10 Excellent "Staff was great and friendly. Room was clean and loved the view. Was surprised there were no washcloths but that’s probably a cultural thing. I know to bring my own for next time. " [](https://expedia.co.uk/Panama-City-Hotels-Principe-Hotel-And-Suites.h7451703.Hotel-Information) ![Las Americas Golden Tower Panama](https://images.trvl-media.com/lodging/10000000/9680000/9675300/9675263/83f7ceed_y.jpg) ### Las Americas Golden Tower Panama 10/10 Excellent "No problems at check in, clean room. Plan on utilizing again when we come back " [](https://expedia.co.uk/Panama-City-Hotels-Las-Americas-Golden-Tower-Panama.h9675263.Hotel-Information) ![Hotel El Panama by Faranda Grand, a member of Radisson Individuals](https://images.trvl-media.com/lodging/1000000/10000/7200/7164/cfc3400a_y.jpg) ### Hotel El Panama by Faranda Grand, a member of Radisson Individuals 10/10 Excellent "Yes nice and clean" [](https://expedia.co.uk/Panama-City-Hotels-Hotel-El-Panama-By-Faranda-Grand.h7164.Hotel-Information) ![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg) ### Hotel Riu Plaza Panama 10/10 Excellent "Everything and everyone were excellent staff and room will Highly recommend and looking forward to another stay there" [](https://expedia.co.uk/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) ![Sheraton Grand Panama](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/179e52b4_y.jpg) ### Sheraton Grand Panama 10/10 Excellent "Nice hotels. " [](https://expedia.co.uk/Panama-City-Hotels-Sheraton-Grand-Panama.h1161.Hotel-Information)