Title: TOP Business Hotels in Panama Canal Zone for 2026 | Expedia.co.uk [Panama Canal Zone Travel Guide](https://expedia.co.uk/Panama-Canal-Zone.dx6222968)[Hotels in Panama Canal Zone](https://expedia.co.uk/Panama-Canal-Zone-Hotels.d6222968.Travel-Guide-Hotels)[Holiday Rentals in Panama Canal Zone](https://expedia.co.uk/Panama-Canal-Zone-Holiday-Rentals.d6222968.Travel-Guide-HolidayRentals)[Flights to Panama Canal Zone](https://expedia.co.uk/Cheap-Flights-To-Panama-Canal-Zone.d6222968.Travel-Guide-Flights)[Panama Canal Zone Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Panama-Canal-Zone.d6222968.Car-Hire-Guide)[Panama Canal Zone Holidays](https://expedia.co.uk/Panama-Canal-Zone.d6222968.Holidays-City-Breaks) ![0_BU000512](https://images.trvl-media.com/place/6222968/089e46e9-cc78-4d6b-b43a-af08a95dd797.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Business Hotels in Panama Canal Zone - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Panama Canal Zone Business Hotels Tonight [8 Jan - 9 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6222968&startDate=2026-01-08&endDate=2026-01-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [9 Jan - 10 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6222968&startDate=2026-01-09&endDate=2026-01-10&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [9 Jan - 11 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6222968&startDate=2026-01-09&endDate=2026-01-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [16 Jan - 18 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6222968&startDate=2026-01-16&endDate=2026-01-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Panama Canal Zone business-friendly hotels ![Garden](https://images.trvl-media.com/lodging/1000000/810000/809200/809149/fe3d7092.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Check-in/check-out kiosk](https://images.trvl-media.com/lodging/1000000/810000/809200/809149/7b45a441.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/1000000/810000/809200/809149/dea447f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/810000/809200/809149/93c6a3dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Radisson Hotel Panama Canal [](https://www.expedia.co.uk/Amador-Hotels-Radisson-Hotel-Panama-Canal.h809149.Hotel-Information) Amador 8.4/10 Very good (1012) "Unbeatable location if your visit is all about the Panama Canal. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Vitaliy £61 includes taxes & fees 7 Feb - 8 Feb [](https://www.expedia.co.uk/Amador-Hotels-Radisson-Hotel-Panama-Canal.h809149.Hotel-Information) ![Poolside bar](https://images.trvl-media.com/lodging/1000000/440000/438200/438135/c696a538.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/440000/438200/438135/c7eb2b99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/440000/438200/438135/daf15c9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/440000/438200/438135/4b5df5ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Gamboa Rainforest Reserve [](https://www.expedia.co.uk/Gamboa-Hotels-Gamboa-Rainforest-Reserve.h438135.Hotel-Information) Colon 7.8/10 Good (679) "Beautiful rooms and grounds. Love ❤️ the nature around the resort." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John £109 includes taxes & fees 21 Jan - 22 Jan [](https://www.expedia.co.uk/Gamboa-Hotels-Gamboa-Rainforest-Reserve.h438135.Hotel-Information) ![2 outdoor pools, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/4000000/3010000/3006200/3006144/f0857b87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/4000000/3010000/3006200/3006144/4608cf45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gazebo](https://images.trvl-media.com/lodging/4000000/3010000/3006200/3006144/d640f143.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/4000000/3010000/3006200/3006144/b19e9542.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Summit Rainforest & Golf Resort [](https://www.expedia.co.uk/Ancon-Hotels-Summit-Rainforest-Golf-Resort.h3006144.Hotel-Information) Panama City 8.4/10 Very good (1000) "Great place to scape for a weekend " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Julisa £79 includes taxes & fees 13 Jan - 14 Jan [](https://www.expedia.co.uk/Ancon-Hotels-Summit-Rainforest-Golf-Resort.h3006144.Hotel-Information) ![Outdoor pool, open 7:00 AM to 8:00 PM, pool umbrellas](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/d26cb29b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/7bb8f38a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/b61be540.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/c617be5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Marriott Panama Hotel [](https://www.expedia.co.uk/Panama-City-Hotels-Marriott-Panama-Hotel.h6099287.Hotel-Information) Panama City 9.0/10 Wonderful (1000) "Great hotel and staff!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Catherine £131 includes taxes & fees 31 Jan - 1 Feb [](https://www.expedia.co.uk/Panama-City-Hotels-Marriott-Panama-Hotel.h6099287.Hotel-Information) ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/3000000/2100000/2096400/2096355/6785cd9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/3000000/2100000/2096400/2096355/b2fe58e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/3000000/2100000/2096400/2096355/cb8e7c14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2100000/2096400/2096355/532b8393.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Panama Canal by IHG [](https://www.expedia.co.uk/Panama-City-Hotels-Holiday-Inn-Panama-Canal.h2096355.Hotel-Information) Panama City 8.6/10 Excellent (446) "The staff was so cordial and nice " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sonny £81 includes taxes & fees 11 Jan - 12 Jan [](https://www.expedia.co.uk/Panama-City-Hotels-Holiday-Inn-Panama-Canal.h2096355.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/67000000/66730000/66723000/66722954/ac5d93a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 9:30 AM to 7:00 PM, pool loungers](https://images.trvl-media.com/lodging/67000000/66730000/66723000/66722954/4df4233d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/67000000/66730000/66723000/66722954/e4736918.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/67000000/66730000/66723000/66722954/a46475aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SAND DIAMOND HOTEL [](https://www.expedia.co.uk/Colon-Hotels-SAND-DIAMOND-HOTEL.h66722954.Hotel-Information) Colon 8.6/10 Excellent (217) "Great hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) DIANA £97 includes taxes & fees 11 Jan - 12 Jan [](https://www.expedia.co.uk/Colon-Hotels-SAND-DIAMOND-HOTEL.h66722954.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/24000000/23810000/23809900/23809852/5cf5cc1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/24000000/23810000/23809900/23809852/14fa725b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/24000000/23810000/23809900/23809852/ea00f846.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/24000000/23810000/23809900/23809852/e9b037a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Cubana Hotel & Residencial [](https://www.expedia.co.uk/Colon-Hotels-La-Cubana-Hotel-Residencial.h23809852.Hotel-Information) Cristobal 8.2/10 Very good (114) "Easy access to colon libre zone" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Everal £28 includes taxes & fees 1 Feb - 2 Feb [](https://www.expedia.co.uk/Colon-Hotels-La-Cubana-Hotel-Residencial.h23809852.Hotel-Information) ![Beach/ocean view](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/665077af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gym](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/1a303895.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/53f67005.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/3000000/2150000/2147400/2147349/402ceb06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Radisson Colon 2,000 Hotel & Casino [](https://www.expedia.co.uk/Colon-Hotels-Radisson-Colon-2.h2147349.Hotel-Information) Barrio Sur 8.2/10 Very good (835) "Staff was very friendly and accommodating. I really enjoyed the breakfast." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Helene £82 includes taxes & fees 24 Jan - 25 Jan [](https://www.expedia.co.uk/Colon-Hotels-Radisson-Colon-2.h2147349.Hotel-Information) ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/877d081d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/8103ef2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/2f37bae5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/757e8465.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Crowne Plaza Panama Airport by IHG [](https://www.expedia.co.uk/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information) Tocumen 8.6/10 Excellent (2385) "Great staff and close to the airport " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) CARLOS ROBERTO £90 includes taxes & fees 15 Jan - 16 Jan [](https://www.expedia.co.uk/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/3972c3df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/166e4001.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch served; local and international cuisine ](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/ea9ff933.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/db85bc00.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City [](https://www.expedia.co.uk/Panama-City-Hotels-The-Santa-Maria.h20958573.Hotel-Information) Juan Diaz 9.6/10 Exceptional (650) "As usual the stay was amazing in this hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jose £183 includes taxes & fees 25 Jan - 26 Jan [](https://www.expedia.co.uk/Panama-City-Hotels-The-Santa-Maria.h20958573.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-22&endDate=2026-01-23®ionId=6222968&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Panama Canal Zone Hotel Reviews ![Hotel El Panama by Faranda Grand, a member of Radisson Individuals](https://images.trvl-media.com/lodging/1000000/10000/7200/7164/cfc3400a_y.jpg) ### Hotel El Panama by Faranda Grand, a member of Radisson Individuals 10/10 Excellent "The staff were very polite and helpful and the room was quite nice. Its my second trip to panama and my second time staying at the hotel. It will always be my place to stay" [](https://expedia.co.uk/Panama-City-Hotels-Hotel-El-Panama-By-Faranda-Grand.h7164.Hotel-Information) ![Plaza Paitilla Inn Hotel](https://images.trvl-media.com/lodging/1000000/530000/527000/526925/a63bd0ec_y.jpg) ### Plaza Paitilla Inn Hotel 10/10 Excellent "The room was very nice with wrap around windows to see the skyline. Beds comfortable, breakfast was very good." [](https://expedia.co.uk/Panama-City-Hotels-Plaza-Paitilla-Inn-Hotel.h526925.Hotel-Information) ![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg) ### Hotel Riu Plaza Panama 10/10 Excellent "5 🌟 " [](https://expedia.co.uk/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) ![The Executive Hotel](https://images.trvl-media.com/lodging/1000000/530000/522100/522086/493046b7_y.jpg) ### The Executive Hotel 10/10 Excellent "Clean room great staff" [](https://expedia.co.uk/Panama-City-Hotels-The-Executive-Hotel.h522086.Hotel-Information) ![Crowne Plaza Panama Airport by IHG](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/877d081d_y.jpg) ### Crowne Plaza Panama Airport by IHG 10/10 Excellent "Staff was very helpful. Shuttle was very convenient and on time Food was great and hotel was clean. Will stay again " [](https://expedia.co.uk/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information) ![Marriott Panama Hotel](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/b61be540_y.jpg) ### Marriott Panama Hotel 10/10 Excellent "Yes very good service. " [](https://expedia.co.uk/Panama-City-Hotels-Marriott-Panama-Hotel.h6099287.Hotel-Information) ![Decapolis Hotel Panama City](https://images.trvl-media.com/lodging/2000000/1090000/1082800/1082793/067e7d25_y.jpg) ### Decapolis Hotel Panama City 10/10 Excellent "Excellent room for my family" [](https://expedia.co.uk/Panama-City-Hotels-Decapolis-Hotel-Panama-City.h1082793.Hotel-Information) ![Waldorf Astoria Panama](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/e7e98c5e_y.jpg) ### Waldorf Astoria Panama 10/10 Excellent "Everything was perfect. Hotel staff was attentive, great amenities, and centrally located. " [](https://expedia.co.uk/Panama-City-Hotels-Waldorf-Astoria-Panama.h4952056.Hotel-Information) ![Las Americas Golden Tower Panama](https://images.trvl-media.com/lodging/10000000/9680000/9675300/9675263/83f7ceed_y.jpg) ### Las Americas Golden Tower Panama 10/10 Excellent "Going location, great city views" [](https://expedia.co.uk/Panama-City-Hotels-Las-Americas-Golden-Tower-Panama.h9675263.Hotel-Information)