Title: Lake Nona Medical City Travel Guide: Best of Lake Nona Medical City, Orlando Travel 2026 | Expedia.co.uk [Hotels in Lake Nona Medical City](https://expedia.co.uk/Lake-Nona-Medical-City-Orlando-Hotels.0-n6197057-0.Travel-Guide-Filter-Hotels)[Flights to Orlando](https://expedia.co.uk/Cheap-Flights-To-Orlando.d178294.Travel-Guide-Flights)[Things to do in Orlando](https://expedia.co.uk/Things-To-Do-In-Orlando.d178294.Travel-Guide-Activities)[Lake Nona Medical City Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Lake-Nona-Medical-City.d6197057.Car-Hire-Guide)[Lake Nona Medical City Holidays](https://expedia.co.uk/Lake-Nona-Medical-City.d6197057.Holidays-City-Breaks) # Lake Nona Medical City Travel Guide ## Orlando ## Visit Lake Nona Medical City Things to do Hotels Where to stay [Orlando travel guide](https://expedia.co.uk/Orlando.dx178294) --- ### Popular places to visit ![Walt Disney World® Resort](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/555000/555500-walt-disney-worldr-resort.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Walt Disney World® Resort Walt Disney World® Resort is part of Orlando. It makes up part of bustling metropolis that is home to 240,000 inhabitants. Walt Disney World® Resort is approximately 15 miles (24 kilometers) from Orlando’s city center. If you are flying in, Walt Disney World® Resort is approximately 15 miles (24 kilometers) from Orlando International Airport. [](https://expedia.co.uk/Walt-Disney-World-Resort-Orlando.d6034120.Attraction) ![Universal Studios Florida](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/492000/492960-universal-studios-orlando.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Universal Studios Florida Movie sets and thrill rides combine to create this internationally acclaimed theme park. [](https://expedia.co.uk/Universal-Studios-Florida-Florida-Center.d6049239.Attraction) ![Universal Studios Florida® showing rides, a city and street scenes](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/22000/22562-Universal-Studios-Orlando.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Universal Orlando Resort Make your Florida vacation one to remember with a stay at this hotel and theme park complex. [](https://expedia.co.uk/Universal-Orlando-Resort-Florida-Center.d6347698.Attraction) ![Disney Springs™](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/438000/438595-Disney-Springsr.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Disney Springs™ You can find the perfect gifts to bring home when you visit Disney Springs™, a favourite shopping spot in Lake Buena Vista. Experience the entertainment choices and acclaimed theatre scene in this family-friendly area. [](https://expedia.co.uk/Disney-SpringsTM-Orlando.d502131.Attraction) ![Magic Kingdom® Theme Park which includes rides](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/35000/35707-Magic-Kingdom.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Magic Kingdom® Park One of the most famous theme parks in the world offers a land of fun and fantasy at the foot of a fairytale castle. [](https://expedia.co.uk/Magic-Kingdom-Park-Bay-Lake.d6123797.Attraction) ![Orange County Convention Center](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/52000/52188-Orange-County-Convention-Centre.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Orange County Convention Center Florida's principal convention center is a large and stunning glass and metal building that hosts national and international trade shows and public events. [](https://expedia.co.uk/Orange-County-Convention-Center-International-Drive-District.d6034972.Attraction) ### Things to do ![Universal Orlando Resort](https://mediaim.expedia.com/localexpert/326356/5d9c8dfe-d368-4628-b402-718c6edaf918.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Universal Orlando Resort Theme Park Tickets £347 per adult **92%** of travellers recommend [](https://expedia.co.uk/things-to-do/universal-orlando-resort-theme-park-tickets.a326356.activity-details) ![Aquatica Orlando](https://mediaim.expedia.com/localexpert/407892/33b09fce-abbf-446b-bce5-738d4c15128d.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Aquatica Orlando £39 per traveller **84%** of travellers recommend [](https://expedia.co.uk/things-to-do/aquatica-orlando.a407892.activity-details) ![Florida: 90 Minute Everglades Cruise](https://mediaim.expedia.com/localexpert/47891876/33dc2687-1323-4f4f-83b1-a21a4a724609.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Florida: 90 Minute Everglades Cruise £41 per adult **100%** of travellers recommend [](https://expedia.co.uk/things-to-do/florida-90-minute-everglades-cruise.a47891876.activity-details) ![Main Court](https://mediaim.expedia.com/localexpert/3828671/4b88bad2-0c7e-40af-9458-02ab4e7c72f6.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### 90 Minute Open Jump at a Trampoline Park in Kissimmee £17 per adult [](https://expedia.co.uk/things-to-do/90-minute-open-jump-at-a-trampoline-park-in-kissimmee.a3828671.activity-details) ![Orlando: Dune Buggy Tour](https://mediaim.expedia.com/localexpert/4525768/6b1d5b22-06df-4e22-abfb-7a7b43569d2d.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Orlando: Dune Buggy Tour £67 per adult **96%** of travellers recommend [](https://expedia.co.uk/things-to-do/orlando-dune-buggy-tour.a4525768.activity-details) ![2-Hour Clear Kayak & Clear Paddleboar](https://mediaim.expedia.com/localexpert/695430/64b46cb0-51fa-464b-9231-a525d0c80253.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### 2-Hour Clear Kayak and Paddleboard(SUP) Rental in Orlando £33 per adult **100%** of travellers recommend [](https://expedia.co.uk/things-to-do/2-hour-clear-kayak-and-paddleboardsup-rental-in-orlando.a695430.activity-details) [See all activities in Orlando](https://expedia.co.uk/Things-To-Do-In-Orlando.d178294.Travel-Guide-Activities) --- ## Top hotels in Lake Nona Medical City ![Wyndham I-Drive Avanti Resort & Conference Center](https://images.trvl-media.com/lodging/1000000/10000/4000/3916/55b45a9e_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Wyndham I-Drive Avanti Resort & Conference Center 6515 International Drive Orlando FL £67 27 Jan - 28 Jan includes taxes & fees Stay at this business-friendly hotel in Orlando. Enjoy free Wi-Fi, free parking and private pools. Our guests praise the pool and the clean rooms in their reviews. ... 7.2/10 Good! (4,039 reviews) Ok Reviewed on 12 Jan 2026 [](https://expedia.co.uk/Hotel-Search?startDate=27%2F01%2F2026&endDate=28%2F01%2F2026&selected=3916&PinnedHotelID=3916&HadPinnedHotel=true®ionId=6197057) ![Universal's Cabana Bay Beach Resort](https://images.trvl-media.com/lodging/6000000/5970000/5963300/5963292/63940f45_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Universal's Cabana Bay Beach Resort 6550 Adventure Way Orlando FL £111 26 Jan - 27 Jan includes taxes & fees Stay at this family-friendly hotel in Orlando. Enjoy free Wi-Fi, 2 outdoor pools and 2 restaurants. Our guests praise the pool and the helpful staff in their ... 8.8/10 Excellent! (6,030 reviews) Nice view of volcano bay clean room comfortable stay Reviewed on 13 Jan 2026 [](https://expedia.co.uk/Hotel-Search?startDate=26%2F01%2F2026&endDate=27%2F01%2F2026&selected=5963292&PinnedHotelID=5963292&HadPinnedHotel=true®ionId=6197057) ![Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando](https://images.trvl-media.com/lodging/1000000/30000/23200/23110/ade3b60d_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando 8800 Vistana Centre Dr Orlando FL £100 5 Feb - 6 Feb includes taxes & fees Stay at this family-friendly hotel in Orlando. Enjoy free Wi-Fi, 6 outdoor pools and 3 restaurants. Our guests praise the pool and the helpful staff in their ... 9.2/10 Wonderful! (4,305 reviews) Excellent Reviewed on 12 Jan 2026 [](https://expedia.co.uk/Hotel-Search?startDate=05%2F02%2F2026&endDate=06%2F02%2F2026&selected=23110&PinnedHotelID=23110&HadPinnedHotel=true®ionId=6197057) ![Rosen Inn at Pointe Orlando](https://images.trvl-media.com/lodging/1000000/10000/8900/8892/8068a653_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Rosen Inn at Pointe Orlando 9000 International Drive Orlando FL £60 9 Feb - 10 Feb includes taxes & fees Stay at this family-friendly hotel in Orlando. Enjoy free Wi-Fi, 3 outdoor pools and 2 coffee shops/cafes. Our guests praise the pool and the helpful staff in ... 8.4/10 Very Good! (5,600 reviews) Everithing was great Reviewed on 12 Jan 2026 [](https://expedia.co.uk/Hotel-Search?startDate=09%2F02%2F2026&endDate=10%2F02%2F2026&selected=8892&PinnedHotelID=8892&HadPinnedHotel=true®ionId=6197057) ![DoubleTree by Hilton at the Entrance to Universal Orlando](https://images.trvl-media.com/lodging/1000000/10000/5400/5398/4997b5df_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### DoubleTree by Hilton at the Entrance to Universal Orlando 5780 Major Blvd Orlando FL £89 25 Jan - 26 Jan includes taxes & fees Stay at this family-friendly hotel in Orlando. Enjoy free Wi-Fi, 2 restaurants and 2 bars/lounges. Our guests praise the pool and the helpful staff in their ... 8.4/10 Very Good! (6,891 reviews) Great stay! The hotel was very clean, comfortable, and well located. The staff was friendly and helpful. I would definitely stay here again.” Reviewed on 8 Jan 2026 [](https://expedia.co.uk/Hotel-Search?startDate=25%2F01%2F2026&endDate=26%2F01%2F2026&selected=5398&PinnedHotelID=5398&HadPinnedHotel=true®ionId=6197057) ![DoubleTree by Hilton Hotel Orlando at SeaWorld](https://images.trvl-media.com/lodging/1000000/20000/18900/18874/69019073_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### DoubleTree by Hilton Hotel Orlando at SeaWorld 10100 International Drive Orlando FL £77 8 Feb - 9 Feb includes taxes & fees Stay at this family-friendly resort in Orlando. Enjoy free Wi-Fi, 2 outdoor pools and 2 restaurants. Our guests praise the breakfast and the pool in their reviews. ... 7.4/10 Good! (6,339 reviews) Beautiful hotel and friendly staff! Reviewed on 8 Jan 2026 [](https://expedia.co.uk/Hotel-Search?startDate=08%2F02%2F2026&endDate=09%2F02%2F2026&selected=18874&PinnedHotelID=18874&HadPinnedHotel=true®ionId=6197057) [See all 27,407 properties in Lake Nona Medical City](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=14%2F01%2F2026&endDate=15%2F01%2F2026®ionId=6197057) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Lake Nona Medical City hotel availability [Tonight ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6197057&startDate=2026-01-13&endDate=2026-01-14)[13 Jan - 14 Jan](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6197057&startDate=2026-01-13&endDate=2026-01-14) [Tomorrow night ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6197057&startDate=2026-01-14&endDate=2026-01-15)[14 Jan - 15 Jan](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6197057&startDate=2026-01-14&endDate=2026-01-15) [This weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6197057&startDate=16%2F01%2F2026&endDate=18%2F01%2F2026)[16 Jan - 18 Jan](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6197057&startDate=16%2F01%2F2026&endDate=18%2F01%2F2026) [Next weekend ](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6197057&startDate=23%2F01%2F2026&endDate=25%2F01%2F2026)[23 Jan - 25 Jan](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6197057&startDate=23%2F01%2F2026&endDate=25%2F01%2F2026) --- ### Other neighbourhoods around Lake Nona Medical City ![Default Image](https://mediaim.expedia.com/destination/2/118e2bcc2c57d221f91d26ed090668ba.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Lake Nona Visitors to Lake Nona enjoy its restaurants, and if you want to do some exploring, USTA National Campus is worth a stop. [](https://expedia.co.uk/Orlando-Lake-Nona.dx6209488) ![Default Image](https://mediaim.expedia.com/destination/2/63b613370a0c99115aa319c73749c410.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Airport North While there might not be top attractions in Airport North, you can explore the larger area and discover places like Ventura Country Club and Hoffner Plaza Shopping Center. [](https://expedia.co.uk/Orlando-Airport-North.dx553248635976479214) ![Default Image](https://images.trvl-media.com/media/content/expus/graphics/deals/TE_Clouds_card_r1.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### South Semoran When in South Semoran, you can plan a visit to Ventura Country Club and Hoffner Plaza Shopping Center, some noteworthy sights in the nearby area. [](https://expedia.co.uk/Orlando-South-Semoran.dx553248635976473903) ![Default Image](https://images.trvl-media.com/media/content/expus/graphics/deals/TE_Clouds_card_r1.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Williamsburg 4.5/5(5 area reviews) Notable for its restaurants, shopping and golf courses, Williamsburg is a sought-after destination for many travellers visiting Orlando. If you want to see some sights in the area, check out Aquatica or Shingle Creek Golf Course. [](https://expedia.co.uk/Orlando-Williamsburg.dx6151795) ![Default Image](https://mediaim.expedia.com/destination/2/173f6a37d0d73a9c521714bf760c8cf0.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Oak Ridge Oak Ridge is noteworthy for its theme parks, and you can make a stop at top attractions like Central Park Plaza Shopping Center and Cross Country Creek. [](https://expedia.co.uk/Orlando-Oak-Ridge.dx6361036) ![Default Image](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/339000/339011-International-Drive-Orlando.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### International Drive District Visitors to International Drive District rave about its breathtaking beach views, exciting theme parks and popular shops. You might also want to make some time to see The Orlando Eye or Pointe Orlando while you're exploring the neighbourhood. [](https://expedia.co.uk/Orlando-International-Drive-District.dx6034244) --- --- - [Stays](?pwaLob=wizard-hotel-pwa-v2) - [Packages](?pwaLob=wizard-package-pwa) - [Flights](?pwaLob=wizard-flight-pwa) - [Things to do](?pwaLob=wizard-lx-pwa) - [Cruises](?pwaLob=wizard-cruise-pwa) - [Cars](?pwaLob=wizard-car-pwa) # Lake Nona Medical City Travel Guide ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - [1 Star Hotels in Southeast Orlando ](https://www.expedia.co.uk/1Star-Southeast-Orlando-Hotels.s10-0-d553248635976478881.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Southeast Orlando ](https://www.expedia.co.uk/3Star-Southeast-Orlando-Hotels.s30-0-d553248635976478881.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Lake Nona ](https://www.expedia.co.uk/5Star-Lake-Nona-Orlando-Hotels.s50-n6209488-0.Travel-Guide-Filter-Hotels) - [Hotels near Eagle Creek Golf Club ](https://www.expedia.co.uk/Eagle-Creek-Golf-Club-Hotels.0-l6128540-0.Travel-Guide-Filter-Hotels) - 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