Lake Nona Medical City Holidays from £592

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Your Lake Nona Medical City Holiday

Our Lake Nona Medical City holiday packages are a simple and practical way to organise and reserve your next escape. Uncover the true character of this unique neighbourhood without the fuss of planning everything yourself. Not sure what to do and see during your trip to Lake Nona Medical City? Nearby attractions such as Austin-Tindall Regional Park, University of Central Florida College of Medicine and Eagle Creek Golf Club are excellent places to start. Expedia will help you turn your ideal Lake Nona Medical City holiday into reality, whatever your budget or travel plans.

Price found within the past 48 hours. Click for updated prices.
Palazzo Lakeside Hotel

Palazzo Lakeside Hotel

3 out of 5
Price was £1,449, price is now £592 per person
£592
per person
20 Oct - 27 Oct
found 13 hours ago
Return direct flight included
London (LHR) to Orlando (MCO)
8.2/10 Very Good! (5,171 reviews)
It was very clean and comfortable! The staff were extremely friendly! The area around the property is really pretty!

Reviewed on 27 Aug 2025

Westgate Palace Hotel / Universal / I-Drive

Westgate Palace Hotel / Universal / I-Drive

4 out of 5
International Drive District
Save 100% on your flight
Price was £1,342, price is now £652 per person
£652
per person
10 Nov - 17 Nov
found 1 day ago
Return direct flight included
London (LHR) to Orlando (MCO)
8.8/10 Excellent! (1,002 reviews)
We didn’t have keys to our room for over 24 hours

Reviewed on 28 Aug 2025

Margaritaville Cottages Orlando with H2O Waterpark by Vstays

Margaritaville Cottages Orlando with H2O Waterpark by Vstays

4 out of 5
Save 100% on your flight
Price was £1,734, price is now £924 per person
£924
per person
10 Nov - 17 Nov
found 1 day ago
Return direct flight included
London (LHR) to Orlando (MCO)
9/10 Wonderful! (1,000 reviews)
What a wonderful experience!. We loved our little cottage, it was perfect space for us and to have somme friends and family visit. The tickets to the water park was a plus!, not crowded and perfect, definitely work the money!

Reviewed on 19 Aug 2025

ette hotel

ette hotel

5 out of 5
Price was £1,693, price is now £913 per person
£913
per person
3 Nov - 10 Nov
found 1 day ago
Return direct flight included
London (LHR) to Orlando (MCO)
9.8/10 Exceptional! (330 reviews)
Excellent service, food, location and staff! Thank you

Reviewed on 11 Aug 2025

The Delaney Hotel

The Delaney Hotel

3.5 out of 5
South Orange
Price was £1,799, price is now £973 per person
£973
per person
3 Nov - 10 Nov
found 1 day ago
Return direct flight included
London (LHR) to Orlando (MCO)
9.6/10 Exceptional! (1,009 reviews)
Property was amazing and one of the cleanest rooms ive ever stayes in.

Reviewed on 24 Aug 2025

Where to stay in Lake Nona Medical City

Find the best Lake Nona Medical City areas and neighborhoods for the activities you enjoy most. Learn more about Lake Nona Medical City
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International Drive District

1 out of top 10 points of interest in this area

Adventure activities, iconic attractions, shopping and world-class dining destinations make this famous street one of Orlando’s most popular tourist attractions.

Find hotels in International Drive District

Top hotels in Lake Nona Medical City

DoubleTree by Hilton at the Entrance to Universal Orlando

DoubleTree by Hilton at the Entrance to Universal Orlando

4 out of 5
5780 Major Blvd, Orlando, FL
Fully refundableReserve now, pay when you stay
The price is £77 per night from 10 Sept to 11 Sept
£77
10 Sept - 11 Sept
includes taxes & fees
8.2/10 Very Good! (6,566 reviews)
"Absolutely will stay again"

Reviewed on 24 Aug 2025

DoubleTree by Hilton at the Entrance to Universal Orlando
Marriott's Grande Vista

Marriott's Grande Vista

4 out of 5
5925 Avenida Vista, Orlando, FL
Fully refundableReserve now, pay when you stay
The price is £73 per night from 21 Sept to 22 Sept
£73
21 Sept - 22 Sept
includes taxes & fees
8.8/10 Excellent! (2,948 reviews)
"Onsite 9 hole golf course was nice. The rooms were simple but clean. We had a nice view of hole 5 on the course. I liked the screened in back patio . The pools were clean and refreshing in the 100 degree days we were there . My son especially liked the pool that played movies. The food was good. ..."

Reviewed on 27 Aug 2025

Marriott's Grande Vista
Universal's Cabana Bay Beach Resort

Universal's Cabana Bay Beach Resort

3.5 out of 5
6550 Adventure Way, Orlando, FL
Fully refundableReserve now, pay when you stay
The price is £118 per night from 3 Sept to 4 Sept
£118
3 Sept - 4 Sept
includes taxes & fees
8.8/10 Excellent! (5,162 reviews)
"very good"

Reviewed on 25 Aug 2025

Universal's Cabana Bay Beach Resort
See all 27,279 properties in Lake Nona Medical City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

How much does a Lake Nona Medical City travel package cost?
Our Lake Nona Medical City travel packages, which start at just £592, are the perfect way to save precious money. All you have to do is choose your preferred hotels, flights and rental car to create your dream escape.
If I'm not able to travel, can I cancel my Lake Nona Medical City travel package?
We totally understand that the universe can throw the odd curveball. If you've locked in a Lake Nona Medical City travel package and need to amend or cancel it, we're here to help. It's always worth looking up our Customer Service Portal first for information. But generally speaking, if you've taken out your package within 24 hours, you may be able to change your itinerary at no cost. If it's been more than 24 hours, your airline, hotel or car rental company may charge a fee.
How do I get a cheap travel package to Lake Nona Medical City?
Book everything all in one place with our Lake Nona Medical City travel packages. You'll find bargains on hotels, flights and more that'll keep your hip pocket happy and adventurous side satisfied. And, with more than 550 air carriers and 1,000,000 properties around the globe to select from, there are endless opportunities to mix and match as you like.
Does Expedia offer Book Now, Pay Later Lake Nona Medical City holidays?
Expedia has teamed up with online lender Klarna to make your next trip easier on the purse strings. Paying in instalments means you can spread the costs of your next dream escape, leaving you with more cash to splash while you're travelling. Klarna has several payment plans to choose from, so you're sure to find something that fits your budget. Consider these flexible payment options:

  • Pay monthly holidays: If paying small amounts each month sounds best for you, Klarna can help. Paying in easy monthly instalments will make your holiday dreams possible.
  • Pay in instalments holidays: If you'd like to pay for your escape across multiple transactions, holidays paid in instalments might be the right choice for your Book Now, Pay Later holiday through Klarna.
  • Low deposit holidays: When you want to grab an incredible deal but your budget doesn't quite cover it yet, Klarna's low deposit holiday plan will help you lock it in.

Where should I stay in Lake Nona Medical City?
Most people who visit Lake Nona Medical City put both Walt Disney World® and SeaWorld® Orlando on their must-see lists. Why not consider a hotel that's close to these popular attractions?
What are the top hotels in Lake Nona Medical City?
If it's your very first time in Lake Nona Medical City, reserve a room at Doubletree By Hilton At The Entrance To Universal Orlando or DoubleTree by Hilton Hotel Orlando at SeaWorld. Both hotels have good amenities and are top options with many savvy travellers.
How far in advance should I book my Lake Nona Medical City holiday?
Savvy travellers often reserve their seats early. You can usually browse through international fares on Expedia up to 12 months before your flight. If you're late to book, don't worry. Cheap prices sometimes become available just weeks before departure dates.
What does an Expedia Lake Nona Medical City travel package include?
It all boils down to what kind of escape you're thinking about. Lake Nona Medical City holiday deals can include flights, car rentals and hotels. You can mix and match to find the package that suits your style and budget. You can also add on activities and experiences after you've booked to score even bigger discounts.
What should I know before booking a Lake Nona Medical City travel package?
When you book your hotels, flights and car rentals together, you'll land amazing discounts. Whether you're organising a wilderness getaway in a cabin or prefer to stay in a comfortable hotel in the city, Expedia can make it happen for less.
Can I choose my airline with a Lake Nona Medical City Expedia travel package?
With a travel package, you're the one in charge. Whether you want to fly to Lake Nona Medical City in first class or coach, simply choose from the available airline options. Expedia has access to over 550 partner airlines worldwide.

Things to do

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£40
per traveller
82% of travellers recommend
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Orlando: Dune Buggy Tour

Orlando: Dune Buggy Tour

£66
per adult
96% of travellers recommend
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Florida: 90 Minute Everglades Cruise

Florida: 90 Minute Everglades Cruise

£37
per adult
100% of travellers recommend
Florida: 90 Minute Everglades Cruise
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.