Lake Nona Medical City Holidays from £880

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to £750 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Packages with flights are ATOL protected

Your Lake Nona Medical City Holiday

Our Lake Nona Medical City holiday packages are a simple and practical way to organise and reserve your next escape. Uncover the true character of this unique neighbourhood without the fuss of planning everything yourself. Not sure what to do and see during your trip to Lake Nona Medical City? Nearby attractions such as Austin-Tindall Regional Park, University of Central Florida College of Medicine and Eagle Creek Golf Club are excellent places to start. Expedia will help you turn your ideal Lake Nona Medical City holiday into reality, whatever your budget or travel plans.

Price found within the past 48 hours. Click for updated prices.
Florida Hotel & Conference Center in the Florida Mall

Florida Hotel & Conference Center in the Florida Mall

3.5 out of 5
Price was £1,283, price is now £880 per person
£880
per person
7 Sept - 14 Sept
found 17 hours ago
Return direct flight included
London (LGW) to Orlando (MCO)
9.2/10 Wonderful! (1,363 reviews)
The staff were all pleasant and friendly! Bed wasvery comfortable. The hotel was very comfortable and love that it was connected to The Florida Mall. It was a great experience for my granddaughter and I.

Reviewed on 8 Jun 2026

Margaritaville Cottages Orlando by Vstays with H2O Waterpark

Margaritaville Cottages Orlando by Vstays with H2O Waterpark

4 out of 5
Save 100% on your flight
Price was £2,212, price is now £1,265 per person
£1,265
per person
19 Aug - 26 Aug
found 1 day ago
Return flight included
Edinburgh (EDI) to Orlando (MCO)
9.2/10 Wonderful! (1,008 reviews)
Loved everything about it.

Reviewed on 8 Jun 2026

The Delaney Hotel

The Delaney Hotel

3.5 out of 5
South Orange
Price was £1,420, price is now £942 per person
£942
per person
19 Aug - 26 Aug
found 1 day ago
Return flight included
Edinburgh (EDI) to Orlando (MCO)
9.6/10 Exceptional! (1,114 reviews)
The Delaney Hotel's in a great location for going to downtown Orlando, as well as the Inter & Co, and Camping World stadiums. It's small and nicely decorated, with an intimate feel. It has 3 floors, and 2 elevators. Lovely outdoor seating area with large umbrellas, (lit up at night-time with twinkling lights!) and easy access to the bar/restaurant from outside! We ate breakfast and dinner in "Delaney's Tavern", on one occasion, and thoroughly enjoyed our food, which was fresh and delicious! Highly recommended! Nate could not do enough for us, and was super nice! All the staff members we spoke with were friendly and very welcoming. The room was clean and spacious, and the bathroom had a great walk-in shower! We really appreciated not having to step into a bath! The hotel parking was a little hard to find initially, until we realised the parking garage was behind the hotel! There's a small multi-storey parking garage directly behind the hotel, which is a very short walk into the hotel itself. The hotel, while on a fairly busy thoroughfare, was not so noisy, as to be intrusive. In fact it didn't bother us at all! We thoroughly enjoyed our brief stay at The Delaney Hotel, and would definitely stay there again!

Reviewed on 16 Jun 2026

Westgate Lakes Resort & Spa Universal Studios Area

Westgate Lakes Resort & Spa Universal Studios Area

4 out of 5
Price was £1,427, price is now £949 per person
£949
per person
18 Jul - 25 Jul
found 11 hours ago
Return direct flight included
London (LHR) to Orlando (MCO)
8.4/10 Very Good! (6,575 reviews)
Great bargain but some things were not in working order like wave pool and deck. There is construction going on in property and it is extremely full of people but it’s big enough that it’s not overwhelming. Very clean.

Reviewed on 17 Jun 2026

Reunion Resort & Golf Club

Reunion Resort & Golf Club

5 out of 5
Reunion
Price was £1,539, price is now £1,096 per person
£1,096
per person
19 Aug - 26 Aug
found 1 day ago
Return flight included
Edinburgh (EDI) to Orlando (MCO)
8.8/10 Excellent! (1,567 reviews)
Yes the facility was amazing

Reviewed on 14 Jun 2026

Where to stay in Lake Nona Medical City

Find the best Lake Nona Medical City areas and neighborhoods for the activities you enjoy most. Learn more about Lake Nona Medical City
International Drive District

International Drive District

Adventure activities, iconic attractions, shopping and world-class dining destinations make this famous street one of Orlando’s most popular tourist attractions.

Find hotels in International Drive District

Top hotels in Lake Nona Medical City

Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando

Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando

4 out of 5
8800 Vistana Centre Dr Orlando FL
The price is £127 per night from 6 Jul to 7 Jul
£127
6 Jul - 7 Jul
includes taxes & fees
9.2/10 Wonderful! (5,815 reviews)
"Excellent accommodations and location!! Immaculate villa and grounds!"

Reviewed on 17 Jun 2026

Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando
DoubleTree by Hilton at the Entrance to Universal Orlando

DoubleTree by Hilton at the Entrance to Universal Orlando

4 out of 5
5780 Major Blvd Orlando FL
Fully refundableReserve now, pay when you stay
The price is £82 per night from 9 Jul to 10 Jul
£82
9 Jul - 10 Jul
includes taxes & fees
8.6/10 Excellent! (7,013 reviews)
"Everything was amazing! Thank you!"

Reviewed on 17 Jun 2026

DoubleTree by Hilton at the Entrance to Universal Orlando
Universal's Cabana Bay Beach Resort

Universal's Cabana Bay Beach Resort

3.5 out of 5
6550 Adventure Way Orlando FL
Fully refundableReserve now, pay when you stay
The price is £126 per night from 22 Jun to 23 Jun
£126
22 Jun - 23 Jun
includes taxes & fees
9/10 Wonderful! (7,076 reviews)
"Nice pool clean toom"

Reviewed on 17 Jun 2026

Universal's Cabana Bay Beach Resort
See all 26,936 properties in Lake Nona Medical City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

Frequently asked questions

How much does a Lake Nona Medical City travel package cost?
Our Lake Nona Medical City travel packages, which start at just £880, are the perfect way to save precious money. All you have to do is choose your preferred hotels, flights and rental car to create your dream escape.
If I'm not able to travel, can I cancel my Lake Nona Medical City travel package?
We totally understand that the universe can throw the odd curveball. If you've locked in a Lake Nona Medical City travel package and need to amend or cancel it, we're here to help. It's always worth looking up our Customer Service Portal first for information. But generally speaking, if you've taken out your package within 24 hours, you may be able to change your itinerary at no cost. If it's been more than 24 hours, your airline, hotel or car rental company may charge a fee.
How do I get a cheap travel package to Lake Nona Medical City?
Book everything all in one place with our Lake Nona Medical City travel packages. You'll find bargains on hotels, flights and more that'll keep your hip pocket happy and adventurous side satisfied. And, with more than 550 air carriers and 1,000,000 properties around the globe to select from, there are endless opportunities to mix and match as you like.
Does Expedia offer Book Now, Pay Later Lake Nona Medical City holidays?
Expedia has teamed up with online lender Klarna to make your next trip easier on the purse strings. Paying in instalments means you can spread the costs of your next dream escape, leaving you with more cash to splash while you're travelling. Klarna has several payment plans to choose from, so you're sure to find something that fits your budget. Consider these flexible payment options:

  • Pay monthly holidays: If paying small amounts each month sounds best for you, Klarna can help. Paying in easy monthly instalments will make your holiday dreams possible.
  • Pay in instalments holidays: If you'd like to pay for your escape across multiple transactions, holidays paid in instalments might be the right choice for your Book Now, Pay Later holiday through Klarna.
  • Low deposit holidays: When you want to grab an incredible deal but your budget doesn't quite cover it yet, Klarna's low deposit holiday plan will help you lock it in.

Where should I stay in Lake Nona Medical City?
Most people who visit Lake Nona Medical City put both Walt Disney World® and SeaWorld® Orlando on their must-see lists. Why not consider a hotel that's close to these popular attractions?
What are the top hotels in Lake Nona Medical City?
If it's your very first time in Lake Nona Medical City, reserve a room at Doubletree By Hilton At The Entrance To Universal Orlando or DoubleTree by Hilton Hotel Orlando at SeaWorld. Both hotels have good amenities and are top options with many savvy travellers.
How far in advance should I book my Lake Nona Medical City holiday?
Savvy travellers often reserve their seats early. You can usually browse through international fares on Expedia up to 12 months before your flight. If you're late to book, don't worry. Cheap prices sometimes become available just weeks before departure dates.
What does an Expedia Lake Nona Medical City travel package include?
It all boils down to what kind of escape you're thinking about. Lake Nona Medical City holiday deals can include flights, car rentals and hotels. You can mix and match to find the package that suits your style and budget. You can also add on activities and experiences after you've booked to score even bigger discounts.
What should I know before booking a Lake Nona Medical City travel package?
When you book your hotels, flights and car rentals together, you'll land amazing discounts. Whether you're organising a wilderness getaway in a cabin or prefer to stay in a comfortable hotel in the city, Expedia can make it happen for less.
Can I choose my airline with a Lake Nona Medical City Expedia travel package?
With a travel package, you're the one in charge. Whether you want to fly to Lake Nona Medical City in first class or coach, simply choose from the available airline options. Expedia has access to over 550 partner airlines worldwide.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.