Lake Nona Medical City Holidays from £584

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Your Lake Nona Medical City Holiday

Our Lake Nona Medical City holiday packages are a simple and practical way to organise and reserve your next escape. Uncover the true character of this unique neighbourhood without the fuss of planning everything yourself. Not sure what to do and see during your trip to Lake Nona Medical City? Nearby attractions such as Austin-Tindall Regional Park, University of Central Florida College of Medicine and Eagle Creek Golf Club are excellent places to start. Expedia will help you turn your ideal Lake Nona Medical City holiday into reality, whatever your budget or travel plans.

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Westgate Town Center Resort

Westgate Town Center Resort

4 out of 5
Price was £817, price is now £584 per person
£584
per person
7 May - 11 May
found 1 day ago
Return flight included
London (LON) to Orlando (MCO)
8/10 Very Good! (1,367 reviews)
The resort as a whole was really great. It was nice to have the water park on site, although it does cost extra, $25 per person, per day. The staff were excellent. The rooms could be cleaner, the floors eapecially and the beds are in serious need of an upgrade. The location was phenomenal if you are going to the Disney parks! I don't think you could get any closer unless you stayed at an actual Disney resort. Overall, I would stay again if the matresses were replaced but I would recommend to others for the convenience of location and the amenities.

Reviewed on 26 Feb 2026

Margaritaville Cottages Orlando with H2O Waterpark by Vstays

Margaritaville Cottages Orlando with H2O Waterpark by Vstays

4 out of 5
Save 100% on your flight
Price was £4,988, price is now £2,784 per person
£2,784
per person
8 Apr - 15 Apr
found 1 day ago
Return flight included
Edinburgh (EDI) to Orlando (MCO)
9.2/10 Wonderful! (1,001 reviews)
Everything was excellent. Beautiful house that was spotless.

Reviewed on 22 Feb 2026

Westgate Lakes Resort & Spa Universal Studios Area

Westgate Lakes Resort & Spa Universal Studios Area

4 out of 5
Price was £1,075, price is now £634 per person
£634
per person
7 May - 11 May
found 1 day ago
Return flight included
London (LON) to Orlando (MCO)
8.2/10 Very Good! (5,482 reviews)
The room was massive, very quiet and clean. We enjoyed the stay

Reviewed on 26 Feb 2026

Ramada Plaza Resort & Suites by Wyndham Orlando Intl Drive

Ramada Plaza Resort & Suites by Wyndham Orlando Intl Drive

3 out of 5
International Drive District
Price was £1,182, price is now £812 per person
£812
per person
12 May - 19 May
found 15 hours ago
Return flight included
London (LON) to Orlando (MCO)
7.8/10 Good! (188 reviews)
Floor was FILTHY. and shower leak all over the bathroom floor.

Reviewed on 26 Feb 2026

Florida Hotel & Conference Center in the Florida Mall

Florida Hotel & Conference Center in the Florida Mall

3.5 out of 5
Price was £1,226, price is now £889 per person
£889
per person
4 May - 11 May
found 1 day ago
Return flight included
London (LGW) to Orlando (MCO)
9.2/10 Wonderful! (2,232 reviews)
Front desk staff was friendly and attentive.

Reviewed on 24 Feb 2026

Where to stay in Lake Nona Medical City

Find the best Lake Nona Medical City areas and neighborhoods for the activities you enjoy most. Learn more about Lake Nona Medical City
International Drive showing landscape views

International Drive District

Adventure activities, iconic attractions, shopping and world-class dining destinations make this famous street one of Orlando’s most popular tourist attractions.

Find hotels in International Drive District

Top hotels in Lake Nona Medical City

Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando

Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando

4 out of 5
8800 Vistana Centre Dr Orlando FL
Fully refundableReserve now, pay when you stay
The price is £109 per night from 22 Mar to 23 Mar
£109
22 Mar - 23 Mar
includes taxes & fees
9.2/10 Wonderful! (4,714 reviews)
Perfect room for stay in Orlando.

Reviewed on 26 Feb 2026

Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando
DoubleTree by Hilton at the Entrance to Universal Orlando

DoubleTree by Hilton at the Entrance to Universal Orlando

4 out of 5
5780 Major Blvd Orlando FL
Fully refundableReserve now, pay when you stay
The price is £88 per night from 30 Mar to 31 Mar
£88
30 Mar - 31 Mar
includes taxes & fees
8.4/10 Very Good! (6,857 reviews)
Room was clean, pillow smelled bad, low hot water in shower, no free coffee bar, food very expensive. Good service, free shuttle to Universal.

Reviewed on 25 Feb 2026

DoubleTree by Hilton at the Entrance to Universal Orlando
Vacation Village Orlando, Celebration

Vacation Village Orlando, Celebration

3 out of 5
2975 Arabian Nights Blvd Kissimmee FL
Fully refundableReserve now, pay when you stay
The price is £93 per night from 15 Mar to 16 Mar
£93
15 Mar - 16 Mar
includes taxes & fees
8.6/10 Excellent! (3,479 reviews)
When I went to check in, after driving an hour in traffic from Orlando, I was told that they didn't have a room for me and I had to drive 45 minutes to another resort. I even pre-checked in online. Nobody said anything to me, no notices, no phone call or email to alert me they didn't have a ...

Reviewed on 26 Feb 2026

Vacation Village Orlando, Celebration
See all 27,168 properties in Lake Nona Medical City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

How much does a Lake Nona Medical City travel package cost?
Our Lake Nona Medical City travel packages, which start at just £584, are the perfect way to save precious money. All you have to do is choose your preferred hotels, flights and rental car to create your dream escape.
If I'm not able to travel, can I cancel my Lake Nona Medical City travel package?
We totally understand that the universe can throw the odd curveball. If you've locked in a Lake Nona Medical City travel package and need to amend or cancel it, we're here to help. It's always worth looking up our Customer Service Portal first for information. But generally speaking, if you've taken out your package within 24 hours, you may be able to change your itinerary at no cost. If it's been more than 24 hours, your airline, hotel or car rental company may charge a fee.
How do I get a cheap travel package to Lake Nona Medical City?
Book everything all in one place with our Lake Nona Medical City travel packages. You'll find bargains on hotels, flights and more that'll keep your hip pocket happy and adventurous side satisfied. And, with more than 550 air carriers and 1,000,000 properties around the globe to select from, there are endless opportunities to mix and match as you like.
Does Expedia offer Book Now, Pay Later Lake Nona Medical City holidays?
Expedia has teamed up with online lender Klarna to make your next trip easier on the purse strings. Paying in instalments means you can spread the costs of your next dream escape, leaving you with more cash to splash while you're travelling. Klarna has several payment plans to choose from, so you're sure to find something that fits your budget. Consider these flexible payment options:

  • Pay monthly holidays: If paying small amounts each month sounds best for you, Klarna can help. Paying in easy monthly instalments will make your holiday dreams possible.
  • Pay in instalments holidays: If you'd like to pay for your escape across multiple transactions, holidays paid in instalments might be the right choice for your Book Now, Pay Later holiday through Klarna.
  • Low deposit holidays: When you want to grab an incredible deal but your budget doesn't quite cover it yet, Klarna's low deposit holiday plan will help you lock it in.

Where should I stay in Lake Nona Medical City?
Most people who visit Lake Nona Medical City put both Walt Disney World® and SeaWorld® Orlando on their must-see lists. Why not consider a hotel that's close to these popular attractions?
What are the top hotels in Lake Nona Medical City?
If it's your very first time in Lake Nona Medical City, reserve a room at Doubletree By Hilton At The Entrance To Universal Orlando or DoubleTree by Hilton Hotel Orlando at SeaWorld. Both hotels have good amenities and are top options with many savvy travellers.
How far in advance should I book my Lake Nona Medical City holiday?
Savvy travellers often reserve their seats early. You can usually browse through international fares on Expedia up to 12 months before your flight. If you're late to book, don't worry. Cheap prices sometimes become available just weeks before departure dates.
What does an Expedia Lake Nona Medical City travel package include?
It all boils down to what kind of escape you're thinking about. Lake Nona Medical City holiday deals can include flights, car rentals and hotels. You can mix and match to find the package that suits your style and budget. You can also add on activities and experiences after you've booked to score even bigger discounts.
What should I know before booking a Lake Nona Medical City travel package?
When you book your hotels, flights and car rentals together, you'll land amazing discounts. Whether you're organising a wilderness getaway in a cabin or prefer to stay in a comfortable hotel in the city, Expedia can make it happen for less.
Can I choose my airline with a Lake Nona Medical City Expedia travel package?
With a travel package, you're the one in charge. Whether you want to fly to Lake Nona Medical City in first class or coach, simply choose from the available airline options. Expedia has access to over 550 partner airlines worldwide.

Things to do

Universal Orlando Resort

Universal Orlando Resort Theme Park Tickets

£427
per adult
92% of travellers recommend
Universal Orlando Resort Theme Park Tickets
Aquatica Orlando

Aquatica Orlando

£39
per traveller
84% of travellers recommend
Aquatica Orlando
Florida: 90 Minute Everglades Cruise

Florida: 90 Minute Everglades Cruise

£40
per adult
100% of travellers recommend
Florida: 90 Minute Everglades Cruise
See all activities in Orlando

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.