Lake Nona Medical City Holidays from £742

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Your Lake Nona Medical City Holiday

Our Lake Nona Medical City holiday packages are a simple and practical way to organise and reserve your next escape. Uncover the true character of this unique neighbourhood without the fuss of planning everything yourself. Not sure what to do and see during your trip to Lake Nona Medical City? Nearby attractions such as Austin-Tindall Regional Park, University of Central Florida College of Medicine and Eagle Creek Golf Club are excellent places to start. Expedia will help you turn your ideal Lake Nona Medical City holiday into reality, whatever your budget or travel plans.

Price found within the past 48 hours. Click for updated prices.
Westgate Blue Tree Resort in Lake Buena Vista

Westgate Blue Tree Resort in Lake Buena Vista

3.5 out of 5
Price was £1,126, price is now £742 per person
£742
per person
13 May - 20 May
found 1 day ago
Return flight included
London (LON) to Orlando (MCO)
8.6/10 Excellent! (1,005 reviews)
Its always a pleasure to stay at Westgate Bluetree! Clean rooms and property, friendly staff and very conveniently located near dusney, outlets, grocery stores and more!!

Reviewed on 1 Apr 2026

Westgate Palace Hotel / Universal / I-Drive

Westgate Palace Hotel / Universal / I-Drive

4 out of 5
International Drive District
Save 100% on your flight
Price was £1,637, price is now £862 per person
£862
per person
6 Jun - 13 Jun
found 18 hours ago
Return flight included
London (LON) to Orlando (MCO)
8.8/10 Excellent! (1,233 reviews)
Everyone was helpful and kind!

Reviewed on 12 Apr 2026

Margaritaville Cottages Orlando by Vstays with H2O Waterpark

Margaritaville Cottages Orlando by Vstays with H2O Waterpark

4 out of 5
Save 100% on your flight
Price was £1,990, price is now £1,057 per person
£1,057
per person
13 May - 20 May
found 1 day ago
Return flight included
London (LON) to Orlando (MCO)
9.2/10 Wonderful! (1,005 reviews)
Hot tub did not work and took 2 days and multiple calls to get it fixed. The grounds were subpar from last time we stayed there, no refreshed landscaping. Usually is very nice but this time felt like a PCB vibe. Probably the last time staying here.

Reviewed on 11 Apr 2026

The Bear's Den Resort Orlando

The Bear's Den Resort Orlando

5 out of 5
Reunion
Save 100% on your flight
Price was £3,575, price is now £2,119 per person
£2,119
per person
6 Jun - 13 Jun
found 18 hours ago
Return flight included
London (LON) to Orlando (MCO)
8/10 Very Good! (23 reviews)
Great place , I recommend it to everyone.

Reviewed on 8 Jan 2025

Westgate Lakes Resort & Spa Universal Studios Area

Westgate Lakes Resort & Spa Universal Studios Area

4 out of 5
Price was £1,534, price is now £968 per person
£968
per person
27 Jun - 4 Jul
found 1 day ago
Return flight included
Manchester (MAN) to Orlando (MCO)
8.4/10 Very Good! (6,071 reviews)
Room was bigger than expected

Reviewed on 13 Apr 2026

Where to stay in Lake Nona Medical City

Find the best Lake Nona Medical City areas and neighborhoods for the activities you enjoy most. Learn more about Lake Nona Medical City
International Drive District

International Drive District

Adventure activities, iconic attractions, shopping and world-class dining destinations make this famous street one of Orlando’s most popular tourist attractions.

Find hotels in International Drive District

Top hotels in Lake Nona Medical City

Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando

Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando

4 out of 5
8800 Vistana Centre Dr Orlando FL
Fully refundableReserve now, pay when you stay
The price is £103 per night from 10 May to 11 May
£103
10 May - 11 May
includes taxes & fees
9.2/10 Wonderful! (5,165 reviews)
Clean room. Had washer and dryer!

Reviewed on 13 Apr 2026

Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando
Universal's Cabana Bay Beach Resort

Universal's Cabana Bay Beach Resort

3.5 out of 5
6550 Adventure Way Orlando FL
Fully refundableReserve now, pay when you stay
The price is £111 per night from 10 May to 11 May
£111
10 May - 11 May
includes taxes & fees
9/10 Wonderful! (6,659 reviews)
Buen hotel. Habitaciones súper limpias y muy buena atención

Reviewed on 13 Apr 2026

Universal's Cabana Bay Beach Resort
Hyatt Regency Orlando International Airport

Hyatt Regency Orlando International Airport

4 out of 5
9300 Jeff Fuqua Boulevard Orlando FL
Fully refundableReserve now, pay when you stay
The price is £191 per night from 26 Apr to 27 Apr
£191
26 Apr - 27 Apr
includes taxes & fees
9.4/10 Exceptional! (4,112 reviews)
The staff were polite, knowledgeable, courteous. The room was clean.

Reviewed on 12 Apr 2026

Hyatt Regency Orlando International Airport
See all 26,647 properties in Lake Nona Medical City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

How much does a Lake Nona Medical City travel package cost?
Our Lake Nona Medical City travel packages, which start at just £742, are the perfect way to save precious money. All you have to do is choose your preferred hotels, flights and rental car to create your dream escape.
If I'm not able to travel, can I cancel my Lake Nona Medical City travel package?
We totally understand that the universe can throw the odd curveball. If you've locked in a Lake Nona Medical City travel package and need to amend or cancel it, we're here to help. It's always worth looking up our Customer Service Portal first for information. But generally speaking, if you've taken out your package within 24 hours, you may be able to change your itinerary at no cost. If it's been more than 24 hours, your airline, hotel or car rental company may charge a fee.
How do I get a cheap travel package to Lake Nona Medical City?
Book everything all in one place with our Lake Nona Medical City travel packages. You'll find bargains on hotels, flights and more that'll keep your hip pocket happy and adventurous side satisfied. And, with more than 550 air carriers and 1,000,000 properties around the globe to select from, there are endless opportunities to mix and match as you like.
Does Expedia offer Book Now, Pay Later Lake Nona Medical City holidays?
Expedia has teamed up with online lender Klarna to make your next trip easier on the purse strings. Paying in instalments means you can spread the costs of your next dream escape, leaving you with more cash to splash while you're travelling. Klarna has several payment plans to choose from, so you're sure to find something that fits your budget. Consider these flexible payment options:

  • Pay monthly holidays: If paying small amounts each month sounds best for you, Klarna can help. Paying in easy monthly instalments will make your holiday dreams possible.
  • Pay in instalments holidays: If you'd like to pay for your escape across multiple transactions, holidays paid in instalments might be the right choice for your Book Now, Pay Later holiday through Klarna.
  • Low deposit holidays: When you want to grab an incredible deal but your budget doesn't quite cover it yet, Klarna's low deposit holiday plan will help you lock it in.

Where should I stay in Lake Nona Medical City?
Most people who visit Lake Nona Medical City put both Walt Disney World® and SeaWorld® Orlando on their must-see lists. Why not consider a hotel that's close to these popular attractions?
What are the top hotels in Lake Nona Medical City?
If it's your very first time in Lake Nona Medical City, reserve a room at Doubletree By Hilton At The Entrance To Universal Orlando or DoubleTree by Hilton Hotel Orlando at SeaWorld. Both hotels have good amenities and are top options with many savvy travellers.
How far in advance should I book my Lake Nona Medical City holiday?
Savvy travellers often reserve their seats early. You can usually browse through international fares on Expedia up to 12 months before your flight. If you're late to book, don't worry. Cheap prices sometimes become available just weeks before departure dates.
What does an Expedia Lake Nona Medical City travel package include?
It all boils down to what kind of escape you're thinking about. Lake Nona Medical City holiday deals can include flights, car rentals and hotels. You can mix and match to find the package that suits your style and budget. You can also add on activities and experiences after you've booked to score even bigger discounts.
What should I know before booking a Lake Nona Medical City travel package?
When you book your hotels, flights and car rentals together, you'll land amazing discounts. Whether you're organising a wilderness getaway in a cabin or prefer to stay in a comfortable hotel in the city, Expedia can make it happen for less.
Can I choose my airline with a Lake Nona Medical City Expedia travel package?
With a travel package, you're the one in charge. Whether you want to fly to Lake Nona Medical City in first class or coach, simply choose from the available airline options. Expedia has access to over 550 partner airlines worldwide.

Things to do

Universal Orlando Resort Theme Park Tickets

Universal Orlando Resort Theme Park Tickets

£462
per adult
92% of travellers recommend
Universal Orlando Resort Theme Park Tickets
Aquatica Orlando

Aquatica Orlando

£40
per traveller
84% of travellers recommend
Aquatica Orlando
Florida: 90 Minute Everglades Cruise

Florida: 90 Minute Everglades Cruise

£41
per adult
100% of travellers recommend
Florida: 90 Minute Everglades Cruise
See all activities in Orlando

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.