
North Clayton Holidays from £1,010
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to £750 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPackages with flights are ATOL protected
Your North Clayton Holiday
Booking a North Clayton holiday package is a wonderful way to get to know the ins and outs of this unique neighbourhood. From its must-visit places to its little-known delights, there's plenty to discover. Some leading nearby attractions to visit during your trip to North Clayton include St. Louis Art Museum, Washington University in St. Louis and Saint Louis Galleria Mall. Expedia will help put your travel plans into action. Book your ultimate North Clayton holiday now.


Moonrise Hotel
Reviewed on 18 Jun 2026

Ameristar Casino Resort and Spa
Reviewed on 14 Jun 2026

DoubleTree by Hilton Hotel St. Louis - Chesterfield
Reviewed on 23 May 2026

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Reviewed on 7 Jun 2026
Where to stay in North Clayton

Downtown St. Louis
Gourmet restaurants beloved sports teams and top sights from Gateway Arch to Busch Stadium – discover Downtown St. Louis, a destination also famous for its historic sites.
Top hotels in North Clayton

Hampton Inn & Suites Clayton/St. Louis-Galleria Area
"They gave us bottle water to brush our teeth with and you have to pay everywhere to park, not quite what I expected for the lofty price."
Reviewed on 18 Jun 2026

Hyatt Regency St. Louis at The Arch
"Room was fine. Had a fun view of the base of the Arch. Pillows and bedding seemed different than other Hyatt Regency hotels I’ve stayed at, not as comfortable and maybe out of a lesser material. The room felt clean and cared for just the same. The room was quiet and sleep was restful. Valet parking ..."
Reviewed on 18 Jun 2026

Clayton Plaza Hotel & Extended Stay
"I had a very nice large room with a living room, large bathroom with tub and shower and a king bed. In all it was nice. The sheets seems old and cheap so that could be better. The breakfast was very good for a complimentary breakfast."
Reviewed on 18 Jun 2026
Frequently asked questions
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.













