Title: The Best Hotels Closest to Museum of Life and Science in Raleigh - 2026 Updated Prices | Expedia.co.uk [Raleigh Travel Guide](https://expedia.co.uk/Raleigh.dx178300)[Holiday Rentals in Raleigh](https://expedia.co.uk/Raleigh-Holiday-Rentals.d178300.Travel-Guide-HolidayRentals)[Flights to Raleigh](https://expedia.co.uk/Cheap-Flights-To-Raleigh.d178300.Travel-Guide-Flights)[Things to do in Raleigh](https://expedia.co.uk/Things-To-Do-In-Raleigh.d178300.Travel-Guide-Activities)[Museum of Life and Science Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Museum-Of-Life-And-Science.d6066241.Car-Hire-Guide)[Museum of Life and Science Holidays](https://expedia.co.uk/Museum-Of-Life-And-Science-Raleigh.d6066241.Attraction) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [8 Apr - 9 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=6066241&startDate=2026-04-08&endDate=2026-04-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [9 Apr - 10 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=6066241&startDate=2026-04-09&endDate=2026-04-10&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [10 Apr - 12 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=6066241&startDate=2026-04-10&endDate=2026-04-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [17 Apr - 19 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=6066241&startDate=2026-04-17&endDate=2026-04-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Property class ## Our top choices for Museum of Life and Science hotels ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/5000000/4650000/4640400/4640309/5d825f74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4650000/4640400/4640309/d095ca5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/5000000/4650000/4640400/4640309/b635c3cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/5000000/4650000/4640400/4640309/cf486635.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Durham/North I-85 [](https://www.expedia.co.uk/Raleigh-Hotels-Hampton-Inn-Suites-Durham-North-I-85.h4640309.Hotel-Information) 0.8 mi from Museum of Life and Science 9.0/10 Wonderful (1,008 reviews) "Had a great stay. Room was very spacious and clean." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kevin £100 includes taxes & fees 19 Apr - 20 Apr [](https://www.expedia.co.uk/Raleigh-Hotels-Hampton-Inn-Suites-Durham-North-I-85.h4640309.Hotel-Information) ![Free buffet breakfast ](https://images.trvl-media.com/lodging/1000000/520000/519800/519791/b3df2a4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/520000/519800/519791/366a4dd4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/520000/519800/519791/1de17076.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/520000/519800/519791/28a254ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Durham by IHG [](https://www.expedia.co.uk/Raleigh-Hotels-Holiday-Inn-Express-Durham.h519791.Hotel-Information) 1.3 mi from Museum of Life and Science 8.8/10 Excellent (986 reviews) "Staff was friendly and breakfast was amazing!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Allen £93 includes taxes & fees 12 Apr - 13 Apr [](https://www.expedia.co.uk/Raleigh-Hotels-Holiday-Inn-Express-Durham.h519791.Hotel-Information) ![Suite, 1 King Bed with Sofa bed, Non Smoking | Premium bedding, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/20000/12400/12352/22181a04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast ](https://images.trvl-media.com/lodging/1000000/20000/12400/12352/fd344660.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12400/12352/ae65d3ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/12400/12352/cec44ae3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Durham near Duke University [](https://www.expedia.co.uk/Raleigh-Hotels-Comfort-Inn-Suites-Durham-Near-Duke-University.h12352.Hotel-Information) Croasdaile Farm Master, 2 mi from Museum of Life and Science 8.6/10 Excellent (1,001 reviews) "Great breakfast and clean rooms." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) C £79 includes taxes & fees 20 Apr - 21 Apr [](https://www.expedia.co.uk/Raleigh-Hotels-Comfort-Inn-Suites-Durham-Near-Duke-University.h12352.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/12100/12096/4b0fbe40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Double Beds (Smoke Free) | Down duvets, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/1000000/20000/12100/12096/9b8ee757.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/12100/12096/eefd1cd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Double Beds (Smoke Free) | Down duvets, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/1000000/20000/12100/12096/effe5fc6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Durham - Duke Univ Medical Center [](https://www.expedia.co.uk/Raleigh-Hotels-Red-Roof-Inn-Durham-Duke-University-Medical-Center.h12096.Hotel-Information) 1.3 mi from Museum of Life and Science 6.8/10 (1,000 reviews) "Close by restaurants" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Neal £55 includes taxes & fees 19 Apr - 20 Apr [](https://www.expedia.co.uk/Raleigh-Hotels-Red-Roof-Inn-Durham-Duke-University-Medical-Center.h12096.Hotel-Information) ![House (3 Bedrooms) | Front of property](https://images.trvl-media.com/lodging/127000000/126580000/126576100/126576024/0b80ea8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/127000000/126580000/126576100/126576024/514df516.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/127000000/126580000/126576100/126576024/6df7ea0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/127000000/126580000/126576100/126576024/14f0d1df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Stylish Durham Retreat - Walkable, Sleeps 6 [](https://www.expedia.co.uk/Raleigh-Hotels-Stylish-Durham-Retreat-Walkable.h126576024.Hotel-Information) 1.7 mi from Museum of Life and Science £429 includes taxes & fees 29 Apr - 30 Apr [](https://www.expedia.co.uk/Raleigh-Hotels-Stylish-Durham-Retreat-Walkable.h126576024.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/93000000/92820000/92816800/92816799/984d892a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/93000000/92820000/92816800/92816799/37e60b13.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/93000000/92820000/92816800/92816799/a7c0ffee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 9:00 AM to 10:00 PM, pool loungers](https://images.trvl-media.com/lodging/93000000/92820000/92816800/92816799/5058af4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Durham University Medical Center [](https://www.expedia.co.uk/Raleigh-Hotels-Hampton-Inn-Suites-DurhamNorth-CampusMedical-Center.h92816799.Hotel-Information) 3 mi from Museum of Life and Science 9.6/10 Exceptional (453 reviews) "Great comfortable stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Miguel £101 includes taxes & fees 19 Apr - 20 Apr [](https://www.expedia.co.uk/Raleigh-Hotels-Hampton-Inn-Suites-DurhamNorth-CampusMedical-Center.h92816799.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/7000000/6240000/6233000/6232983/9047a750.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/7000000/6240000/6233000/6232983/84262960.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/7000000/6240000/6233000/6232983/8a466914.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/7000000/6240000/6233000/6232983/3b234d8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn Durham/University Medical Center [](https://www.expedia.co.uk/Raleigh-Hotels-Hilton-Garden-Inn-DurhamUniversity-Medical-Center.h6232983.Hotel-Information) 9th Street District, 2.1 mi from Museum of Life and Science 9.2/10 Wonderful (1,004 reviews) "Clean room and friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christina £125 includes taxes & fees 20 Apr - 21 Apr [](https://www.expedia.co.uk/Raleigh-Hotels-Hilton-Garden-Inn-DurhamUniversity-Medical-Center.h6232983.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/16000000/15940000/15936000/15935986/0914b52f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/16000000/15940000/15936000/15935986/80575909.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily cooked-to-order breakfast for a fee](https://images.trvl-media.com/lodging/16000000/15940000/15936000/15935986/f3579d7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Suite, 1 King Bed | In-room safe, blackout curtains, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/16000000/15940000/15936000/15935986/b6b938c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### JB Duke Hotel [](https://www.expedia.co.uk/Raleigh-Hotels-JB-Duke-Hotel.h15935986.Hotel-Information) 3.5 mi from Museum of Life and Science 9.4/10 Exceptional (588 reviews) "Everything is always amazing when I stay here. The staff is very helpful and accomodating." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Georgette £143 includes taxes & fees 20 Apr - 21 Apr [](https://www.expedia.co.uk/Raleigh-Hotels-JB-Duke-Hotel.h15935986.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/11000000/10350000/10344600/10344567/0f42bc80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/11000000/10350000/10344600/10344567/b6927f21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/11000000/10350000/10344600/10344567/c90f9818.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/11000000/10350000/10344600/10344567/8b8fb57c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Residence Inn Durham McPherson/Duke University Medical Cntr [](https://www.expedia.co.uk/Raleigh-Hotels-Residence-Inn-Durham-McPhersonDuke-University-Medical-Cntr.h10344567.Hotel-Information) Trinity Park, 2 mi from Museum of Life and Science 9.2/10 Wonderful (470 reviews) "Courteous staff, spotless rooms, comfortable bed and pillows." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anna F £149 includes taxes & fees 3 May - 4 May [](https://www.expedia.co.uk/Raleigh-Hotels-Residence-Inn-Durham-McPhersonDuke-University-Medical-Cntr.h10344567.Hotel-Information) ![Hallway](https://images.trvl-media.com/lodging/2000000/1470000/1464500/1464431/80e8b722.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property – evening/night](https://images.trvl-media.com/lodging/2000000/1470000/1464500/1464431/81950088.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1470000/1464500/1464431/39dc9c71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave](https://images.trvl-media.com/lodging/2000000/1470000/1464500/1464431/fa7de522.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### University Inn Durham next to Duke University Medical Center [](https://www.expedia.co.uk/Raleigh-Hotels-University-Inn-Durham-Next-To-Duke-University-Medical-Center.h1464431.Hotel-Information) 2.5 mi from Museum of Life and Science 9.0/10 Wonderful (1,000 reviews) "Large room, comfortable bed, kind staff, very clean. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Yolonda £96 includes taxes & fees 29 Apr - 30 Apr [](https://www.expedia.co.uk/Raleigh-Hotels-University-Inn-Durham-Next-To-Duke-University-Medical-Center.h1464431.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/67000000/66580000/66571500/66571463/42139333.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/67000000/66580000/66571500/66571463/1e73f22d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/67000000/66580000/66571500/66571463/25d993ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/67000000/66580000/66571500/66571463/0104cf5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SpringHill Suites by Marriott Durham City View [](https://www.expedia.co.uk/Raleigh-Hotels-SpringHill-Suites-By-Marriott-Durham-City-View.h66571463.Hotel-Information) 2.8 mi from Museum of Life and Science 9.2/10 Wonderful (498 reviews) "Nice stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mary £116 includes taxes & fees 12 Apr - 13 Apr [](https://www.expedia.co.uk/Raleigh-Hotels-SpringHill-Suites-By-Marriott-Durham-City-View.h66571463.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/67000000/66800000/66794200/66794113/493b3869.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic Area](https://images.trvl-media.com/lodging/67000000/66800000/66794200/66794113/336169a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Mini-fridge, coffee/tea maker](https://images.trvl-media.com/lodging/67000000/66800000/66794200/66794113/7569d627.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/67000000/66800000/66794200/66794113/258a1fd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AC Hotel Durham [](https://www.expedia.co.uk/Raleigh-Hotels-AC-Hotel-Durham.h66794113.Hotel-Information) 3 mi from Museum of Life and Science 9.2/10 Wonderful (654 reviews) "Good location. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Silvia £136 includes taxes & fees 12 Apr - 13 Apr [](https://www.expedia.co.uk/Raleigh-Hotels-AC-Hotel-Durham.h66794113.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/1000000/20000/10900/10844/a7fd54b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/20000/10900/10844/7e33e583.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/20000/10900/10844/fb0066de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Yoga](https://images.trvl-media.com/lodging/1000000/20000/10900/10844/a5fd444c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Washington Duke Inn & Golf Club [](https://www.expedia.co.uk/Raleigh-Hotels-Washington-Duke-Inn-Golf-Club.h10844.Hotel-Information) 3.7 mi from Museum of Life and Science 9.4/10 Exceptional (1,000 reviews) "The Hotel was Clean. Very well maintained throughout the buildings and grounds. Very friendly and helpful staff. Would definitely stay there again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Richard £170 includes taxes & fees 12 Apr - 13 Apr [](https://www.expedia.co.uk/Raleigh-Hotels-Washington-Duke-Inn-Golf-Club.h10844.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/11000000/10090000/10088800/10088739/3a03b169.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, City View | Hypo-allergenic bedding, down duvets, pillow-top beds, in-room safe](https://images.trvl-media.com/lodging/11000000/10090000/10088800/10088739/9f21eef5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/11000000/10090000/10088800/10088739/505e32af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/11000000/10090000/10088800/10088739/e2c18e4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aloft Durham Downtown [](https://www.expedia.co.uk/Raleigh-Hotels-Aloft-Durham-Downtown.h10088739.Hotel-Information) American Tobacco District, 2.5 mi from Museum of Life and Science 9.0/10 Wonderful (743 reviews) "Clean room Friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sierra £172 includes taxes & fees 26 Apr - 27 Apr [](https://www.expedia.co.uk/Raleigh-Hotels-Aloft-Durham-Downtown.h10088739.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/11000000/11000000/10995500/10995456/49daf4fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee shop](https://images.trvl-media.com/lodging/11000000/11000000/10995500/10995456/6ad3b381.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/11000000/11000000/10995500/10995456/f7b4838d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/11000000/11000000/10995500/10995456/3439b81c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Durham Hotel [](https://www.expedia.co.uk/Raleigh-Hotels-The-Durham-Hotel.h10995456.Hotel-Information) Downtown Durham, 2.2 mi from Museum of Life and Science 9.0/10 Wonderful (676 reviews) "Stayed here for the proximity to MotorCo for a concert. Excellent location and property was excellent" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gretchen £158 includes taxes & fees 12 Apr - 13 Apr [](https://www.expedia.co.uk/Raleigh-Hotels-The-Durham-Hotel.h10995456.Hotel-Information) ![Standard Double Room, 1 Double Bed, Non Smoking | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/126000000/125790000/125783500/125783460/27e9f25b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/126000000/125790000/125783500/125783460/251c311e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/126000000/125790000/125783500/125783460/w1080h1480x0y430-85a0d8d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/126000000/125790000/125783500/125783460/w1080h1478x0y431-2c6c9364.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Budget Inn [](https://www.expedia.co.uk/Raleigh-Hotels-Budget-Inn.h125783460.Hotel-Information) 3.3 mi from Museum of Life and Science 9.0/10 Wonderful (9 reviews) "The room was clean and comfortable, the staff was cordial and there was quick access to an interstate highway." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Charles £55 includes taxes & fees 9 Apr - 10 Apr [](https://www.expedia.co.uk/Raleigh-Hotels-Budget-Inn.h125783460.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/20000/12900/12880/3ad3b6bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/1000000/20000/12900/12880/2ecbbac9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Snack bar](https://images.trvl-media.com/lodging/1000000/20000/12900/12880/40f303ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/20000/12900/12880/7f82e6fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Lodge at Duke Medical Center [](https://www.expedia.co.uk/Raleigh-Hotels-The-Lodge-At-Duke-Medical-Center.h12880.Hotel-Information) 2.5 mi from Museum of Life and Science 8.6/10 Excellent (1,001 reviews) "We enjoy staying here. Friendly staff and great location. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gerard and Catherine £122 includes taxes & fees 9 Apr - 10 Apr [](https://www.expedia.co.uk/Raleigh-Hotels-The-Lodge-At-Duke-Medical-Center.h12880.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/20000/18900/18821/aa0fe1f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, open 9:00 AM to 9:00 PM, pool umbrellas](https://images.trvl-media.com/lodging/1000000/20000/18900/18821/09c549f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/20000/18900/18821/d346cc1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/18900/18821/5fa76fa4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Durham near Duke University [](https://www.expedia.co.uk/Raleigh-Hotels-Hilton-Durham-Near-Duke-University.h18821.Hotel-Information) 3.3 mi from Museum of Life and Science 8.6/10 Excellent (1,003 reviews) "Nice area, great hotel restaurant " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sam £97 includes taxes & fees 15 Apr - 16 Apr [](https://www.expedia.co.uk/Raleigh-Hotels-Hilton-Durham-Near-Duke-University.h18821.Hotel-Information) ![BBQ/picnic Area](https://images.trvl-media.com/lodging/1000000/50000/42800/42705/6d146009.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/50000/42800/42705/29cfc65c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily full breakfast for a fee](https://images.trvl-media.com/lodging/1000000/50000/42800/42705/b867beff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42800/42705/45c09dc6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard Durham Near Duke University/Downtown [](https://www.expedia.co.uk/Raleigh-Hotels-Courtyard-By-Marriott-Durham.h42705.Hotel-Information) Croasdaile Farm Master, 2.1 mi from Museum of Life and Science 8.2/10 Very good (1,001 reviews) "A couple of good places to eat nearby --- walkable. It was an easy place to stay while traveling north on 1-85." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nina £79 includes taxes & fees 19 Apr - 20 Apr [](https://www.expedia.co.uk/Raleigh-Hotels-Courtyard-By-Marriott-Durham.h42705.Hotel-Information) ![Interior entrance](https://images.trvl-media.com/lodging/9000000/8730000/8720800/8720744/a66cf407.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Ballroom](https://images.trvl-media.com/lodging/9000000/8730000/8720800/8720744/52832fe3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property – evening/night](https://images.trvl-media.com/lodging/9000000/8730000/8720800/8720744/108f8814.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lunch, dinner, brunch served; American cuisine ](https://images.trvl-media.com/lodging/9000000/8730000/8720800/8720744/46003326.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 21c Museum Hotel Durham [](https://www.expedia.co.uk/Raleigh-Hotels-21c-Museum-Hotel-Durham.h8720744.Hotel-Information) Downtown Durham, 2.3 mi from Museum of Life and Science 8.4/10 Very good (1,004 reviews) "Exceptional staff, very responsive. And very pet-friendly!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Megan £140 includes taxes & fees 3 May - 4 May [](https://www.expedia.co.uk/Raleigh-Hotels-21c-Museum-Hotel-Durham.h8720744.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-04-22&endDate=2026-04-23®ionId=6066241&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Top Museum of Life and Science Hotel Reviews ![Holiday Inn Express Durham by IHG](https://images.trvl-media.com/lodging/1000000/520000/519800/519791/b3df2a4a_y.jpg) ### Holiday Inn Express Durham by IHG 8/10 Good "Not bad!!! 24 hr coffee. Fairly close to DpAC" [](https://expedia.co.uk/Raleigh-Hotels-Holiday-Inn-Express-Durham.h519791.Hotel-Information) ![Hampton Inn & Suites Durham/North I-85](https://images.trvl-media.com/lodging/5000000/4650000/4640400/4640309/5d825f74_y.jpg) ### Hampton Inn & Suites Durham/North I-85 10/10 Excellent "Hotel was nice and clean. Breakfast was great. Staff were kind and courteous. I would have loved if the indoor pool was heated a little. Overall great experience." [](https://expedia.co.uk/Raleigh-Hotels-Hampton-Inn-Suites-Durham-North-I-85.h4640309.Hotel-Information) ![Comfort Inn & Suites Durham near Duke University](https://images.trvl-media.com/lodging/1000000/20000/12400/12352/22181a04_y.jpg) ### Comfort Inn & Suites Durham near Duke University 10/10 Excellent "Rooms were very clean and loved the night light in the bathroom." [](https://expedia.co.uk/Raleigh-Hotels-Comfort-Inn-Suites-Durham-Near-Duke-University.h12352.Hotel-Information) ![Courtyard Durham Near Duke University/Downtown](https://images.trvl-media.com/lodging/1000000/50000/42800/42705/6d146009_y.jpg) ### Courtyard Durham Near Duke University/Downtown 2/10 Terrible "The beds were very painful. Couldn’t stay both nights due to the beds and the manager was not helpful at all trying to resolve it." [](https://expedia.co.uk/Raleigh-Hotels-Courtyard-By-Marriott-Durham.h42705.Hotel-Information) ![21c Museum Hotel Durham](https://images.trvl-media.com/lodging/9000000/8730000/8720800/8720744/52832fe3_y.jpg) ### 21c Museum Hotel Durham 10/10 Excellent "Prime location for events at DPAC. " [](https://expedia.co.uk/Raleigh-Hotels-21c-Museum-Hotel-Durham.h8720744.Hotel-Information) ![Drexall Haven - Stylish + Peaceful Stay](https://images.trvl-media.com/lodging/124000000/123140000/123139100/123139066/4c2486c2_y.jpg) ### Drexall Haven - Stylish + Peaceful Stay 10/10 Excellent "Very clean and comfortable property. Check in was easy and we had the door code via email. Simple check out. Fast communication when questions came up. Beds were very comfortable and the electric fireplace was beautiful. " [](https://expedia.co.uk/Raleigh-Hotels-Drexall-Haven-Stylish-Peaceful-Stay.h123139066.Hotel-Information) ![Guest House with private Gate Near Downtown Durham Peaceful 2-bedroom 2 Bathroom](https://images.trvl-media.com/lodging/124000000/123870000/123866600/123866547/bb9e97f7_y.jpg) ### Guest House with private Gate Near Downtown Durham Peaceful 2-bedroom 2 Bathroom 10/10 Excellent "We had a wonderful stay and would definitely book again. Alexis was a fantastic host—kind, responsive, and very attentive. He made himself available whenever we needed anything and truly ensured we were comfortable throughout our stay.The home was clean, well-maintained, and thoughtfully stocked. The beds were very comfortable, and we appreciated the added touches like shampoo, conditioner, body wash in both bathrooms, and plenty of clean towels.It’s also a great place for dog owners. Alexis has a large, very friendly dog, which made the space feel welcoming and accommodating for pets.Overall, a great experience with a host who genuinely cares about his guests." [](https://expedia.co.uk/Raleigh-Hotels-Guest-House-With-Private-Gate-Near-Downtown-Durham-Peaceful-2-Bedroom-2-Bathroom.h123866547.Hotel-Information) ![Red Roof Inn Durham - Duke Univ Medical Center](https://images.trvl-media.com/lodging/1000000/20000/12100/12096/4b0fbe40_y.jpg) ### Red Roof Inn Durham - Duke Univ Medical Center 10/10 Excellent "Warren Buffett would approve of your smart decision to stay here. This is a safe, clean and economical place to stay, and close to everything. I appreciate the proprietors kindness and welcoming greeting. It’s a great value for your travel dollar. " [](https://expedia.co.uk/Raleigh-Hotels-Red-Roof-Inn-Durham-Duke-University-Medical-Center.h12096.Hotel-Information) ![Durham Retreat: Deck, Grill, Firepit, 10 mins from Duke & Downtown](https://images.trvl-media.com/lodging/73000000/72300000/72294900/72294847/32105a96_y.jpg) ### Durham Retreat: Deck, Grill, Firepit, 10 mins from Duke & Downtown 10/10 Excellent "The kitchen was pretty well equipped. Would have liked baggies, more temp storage containers, tissues somewhere. Small things at a comfy and lovely place. Quiet neighborhood. Soft sheets and pillows, great mattresses. " [](https://expedia.co.uk/Durham-Hotels-Durham-Retreat-Deck.h72294847.Hotel-Information) ## Hotels near other Museum of Life and Science attractions ### Brightleaf Square You can do some window-shopping at Brightleaf Square during your visit to Durham. Discover the lively festivals and stunning cathedral in this family-friendly area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532657772) ### Vietnam Veterans Living Memorial You can find out about the history of Durham with a trip to Vietnam Veterans Living Memorial. Attend a sporting event or visit the stunning cathedral in this family-friendly area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621564886205) ### Northgate Mall You can search for that perfect souvenir at Northgate Mall during your stay in Durham. Experience the lively festivals or attend a sporting event in this family-friendly area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621564886206) ### Duke Homestead Learn about the local history of Durham when you take a trip to Duke Homestead. Attend a sporting event or visit the stunning cathedral in this family-friendly area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532657783) ### Fullsteam Brewery You can take time to visit Fullsteam Brewery during your travels to Durham. Experience the lively festivals or attend a sporting event in this family-friendly area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621564886207) ### Durham Convention Center 4.1/5 (118 reviews) Learn about the events happening in Durham Convention Center during your trip to Durham. Discover the lively festivals and stunning cathedral in this family-friendly area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532657774) ### African American Dance Ensemble You can enjoy some culture when you stop by African American Dance Ensemble in Durham. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=658956701486178304) ### Carolina Theatre 4.1/5 (220 reviews) You can get tickets for a performance at Carolina Theatre during your stay in Durham. Experience the area's entertainment choices or attend a sporting event. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6066237) ## Frequently asked questions ### What's the area like around Museum of Life and Science? ### What's the best hotel to stay near Museum of Life and Science? ### How many hotels can I expect to find close to Museum of Life and Science? ### If I need to cancel the hotel reservation for my stay near Museum of Life and Science, will I receive a refund? ### What can I see and do near Museum of Life and Science?