Title: Midsize South America Car Hire | Expedia.co.uk ![](https://images.trvl-media.com/place/6140917/ba4ee8aa-2da1-4310-8a44-1015fb6e7a3d.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Midsize Car Hire Companies in South America - ![protection illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__protection.svg) ### Change your mind Penalty-free cancellation on many/select car hire - ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Treat yourself One Key members save 10% or more on over 1 million car hire [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![package illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__package.svg) ### Shop smart Compare car suppliers and package your flight, hotel, and car to save ## Find Cheap Midsize Car Deals for South America Mon, 22 Dec - Tue, 23 Dec ### Midsize 4/5 Door Car Fiat Siena 4P or similar or similar - 5 people - Unlimited mileage ![FlexWays](//mediaim.expedia.com/cars/logos/FS.png) #### Pick-up location Cuiaba International Airport - Marechal Rondon, Cuiaba, BRA 4.1 mi from South America city centre ![Fiat Siena 4P or similar](https://mediaim.expedia.com/cars/1152/c7966f2f-4f66-41fe-8730-ce2a67ae309b.jpg?impolicy=resizecrop&ra=fit&rh=165&rw=165) #### £40 total found 0 minutes ago [](https://expedia.co.uk/carsearch?olat=-15.65072&olon=-56.12038&totalprice=39.97¤cy=GBP&date1=22/12/2025&date2=23/12/2025&clientrfrr=CarMarketingLandingPages&tprfrr=39.97&cvrfrr=FS&ctrfrr=ID&piid=AQqD1ihPMo6S0NbXU65rYd57avjCnI7in9MF41jMKsvon6GbXkLhaQNNgBxcYrubdvr9aVTSWkx85jg3dmcdJ2qUG6Jtoy8UmS6ESYa3-bi7U&selCC=[%22midsize%22]) Mon, 22 Dec - Tue, 23 Dec ### Midsize 4/5 Door Car Fiat Cronos AT or similar or similar - 5 people - Unlimited mileage ![FlexWays](//mediaim.expedia.com/cars/logos/FS.png) #### Pick-up location Cuiaba International Airport - Marechal Rondon, Cuiaba, BRA 4.1 mi from South America city centre ![Fiat Cronos AT or similar](https://mediaim.expedia.com/cars/1152/6707c6bd-4694-4882-827f-7d2a92c85aef.jpg?impolicy=resizecrop&ra=fit&rh=165&rw=165) #### £47 total found 0 minutes ago [](https://expedia.co.uk/carsearch?olat=-15.65072&olon=-56.12038&totalprice=47.44¤cy=GBP&date1=22/12/2025&date2=23/12/2025&clientrfrr=CarMarketingLandingPages&tprfrr=47.44&cvrfrr=FS&ctrfrr=ID&piid=AQqD1ihPMo6S0NbXU65rYd57avjCnI7in9MF41jMKsvon6GbXkLhaQNNgBxcYrubdvIQl3IQhzArHkCOA-UUuvwkG6Jtoy8UmS6ESYa3-bi7U&selCC=[%22midsize%22]) Mon, 22 Dec - Tue, 23 Dec ### Midsize 4/5 Door Car Citroen C3 Air Cross 1.0 turbo or similar or similar - 5 people - Unlimited mileage ![Localiza](//mediaim.expedia.com/cars/logos/LL.png) #### Pick-up location Av. Joao Ponce De Arruda, 840-Centro Norte, Cuiaba, BRA 4.14 mi from South America city centre ![Citroen C3 Air Cross 1.0 turbo or similar](https://mediaim.expedia.com/cars/1063/05ba8026-603e-4320-b7ce-a636162d4f47.jpg?impolicy=resizecrop&ra=fit&rh=165&rw=165) #### £68 total found 0 minutes ago [](https://expedia.co.uk/carsearch?olat=-15.651428&olon=-56.120292&totalprice=67.78¤cy=GBP&date1=22/12/2025&date2=23/12/2025&clientrfrr=CarMarketingLandingPages&tprfrr=67.78&cvrfrr=LL&ctrfrr=ID&piid=AQqD1ihPMo6S0NbXU65rYd57avjCnI7in9MF41jMKsvoksT_0R2rmcaust3wvUZvce69GJCC47P8f_NxhNWRZCMaVfiYSys3c_aFMAGUFa3qg&selCC=[%22midsize%22]) Mon, 22 Dec - Tue, 23 Dec ### Midsize SUV Jeep Renegade 1.3 Turbo or similar or similar - 5 people - Unlimited mileage ![Localiza](//mediaim.expedia.com/cars/logos/LL.png) #### Pick-up location Av. Joao Ponce De Arruda, 840-Centro Norte, Cuiaba, BRA 4.14 mi from South America city centre ![Jeep Renegade 1.3 Turbo or similar](https://mediaim.expedia.com/cars/1063/384b62c6-1385-44bc-8da6-e198610fd3f8.jpg?impolicy=resizecrop&ra=fit&rh=165&rw=165) #### £69 total found 0 minutes ago [](https://expedia.co.uk/carsearch?olat=-15.651428&olon=-56.120292&totalprice=69.15¤cy=GBP&date1=22/12/2025&date2=23/12/2025&clientrfrr=CarMarketingLandingPages&tprfrr=69.15&cvrfrr=LL&ctrfrr=IF&piid=AQqD1ihPMo6S0NbXU65rYd57avjCnI7in9MF41jMKsvoksT_0R2rmcaust3wvUZvcenjBem2WD2ZI50twLy6itmaVfiYSys3c_aFMAGUFa3qg&selCC=[%22suv%22]) Mon, 22 Dec - Tue, 23 Dec ### Midsize Elite 4/5 Door Car VW T-Cross Highline or similar or similar - 5 people - Unlimited mileage ![Localiza](//mediaim.expedia.com/cars/logos/LL.png) #### Pick-up location Av. Joao Ponce De Arruda, 840-Centro Norte, Cuiaba, BRA 4.14 mi from South America city centre ![VW T-Cross Highline or similar](https://mediaim.expedia.com/cars/1063/dcd812d4-2874-492e-bd65-746a492c9359.jpg?impolicy=resizecrop&ra=fit&rh=165&rw=165) #### £77 total found 0 minutes ago [](https://expedia.co.uk/carsearch?olat=-15.651428&olon=-56.120292&totalprice=77.18¤cy=GBP&date1=22/12/2025&date2=23/12/2025&clientrfrr=CarMarketingLandingPages&tprfrr=77.18&cvrfrr=LL&ctrfrr=JD&piid=AQqD1ihPMo6S0NbXU65rYd57avjCnI7in9MF41jMKsvokSqwsp-XooR4UxcCfpR3ljex19Rejx0eXX1UXcZ6fysVZzOORFZSNk2CGHtP-uhwo&selCC=[%22midsize%22]) Mon, 22 Dec - Tue, 23 Dec ### Midsize 4/5 Door Car Fiat Pulse Audace or similar or similar - 5 people - Unlimited mileage ![Alamo Rent A Car](//mediaim.expedia.com/cars/logos/AL.png) #### Pick-up location Gov Joao Ponce De Arruda, Varzea Grande 78110-376, BRA 4.14 mi from South America city centre ![Fiat Pulse Audace or similar](https://mediaim.expedia.com/cars/6/110fc6fe-5096-4a32-902c-c12cb8c1d0a7.jpg?impolicy=resizecrop&ra=fit&rh=165&rw=165) #### £108 total found 0 minutes ago [](https://expedia.co.uk/carsearch?olat=-15.65142&olon=-56.12029&totalprice=107.57¤cy=GBP&date1=22/12/2025&date2=23/12/2025&clientrfrr=CarMarketingLandingPages&tprfrr=107.57&cvrfrr=AL&ctrfrr=ID&piid=AQqD1ihPMo6S0NbXU65rYd57avjCnI7in9MF41jMKsvolCXWZDS9m_Yg5_90kHFHm4ChZHelVawbOIbjpuybRAblvEDMAJmfBSqdgxPgIjnuQ&selCC=[%22midsize%22]) ### Don't see what you're looking for? See all car hire in South America [View all cars](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=South%20America&dpln=6023117&date1=28/12/2025&date2=30/12/2025&crfrr=defaultFlex&SearchType=Place&selCC=[%22midsize%22]) ## Frequently asked questions | Midsize Car hire in South America #### Where can I hire Midsize cars in South America? In South America, multiple suppliers are offering Midsize cars at an excellent price. Compare locations and providers on Expedia.co.uk to find the best deal for what you’re looking for. The airport location generally has the largest selection to choose from. #### How can I find the best deals on Midsize car hire in South America? You can see all the offers available for Midsize car hire in South America and then compare prices from various providers and pick-up locations. Prices may vary depending on which supplier you choose, the pick-up location and the dates of your trip. You can also browse deals for other car types on our car hire in South America page. #### What is the cancellation policy for car hire in South America? Each car hire deal has its own cancellation policy. Some bookings are free to cancel while most pre-paid bookings are non-refundable. We recommend filtering by “Free cancellation” to see the most flexible options. #### Why is Expedia.co.uk the best place to book a hire car? Here at Expedia.co.uk, we go the extra mile, so you can too! You’ll select your Midsize hire car in South America from a large stock and get the best deals available from suppliers in the area. You’ll get rewards back from every booking, and can customise your entire trip itinerary, all in one place. We have the best deals, not only on car hire but also on hotels in South America. Bundle them into one, and you’ll get a holiday package in South America for less. ## Midsize Car Rental in South America Welcome to the South America Midsize car rental page, offering you major savings on your next car hire is our top priority! Lucky for you, we have many different Midsize Car class pick up locations across the city, which makes it easy and convenient to rent a Midsize car in South America. It’s as simple as: 1. Add pick up and drop off information to the wizard 2. Select Midsize from the Advanced Option menu 3. Hit "Search" 4. Compare and filters the offers that best fit your budget and needs! Don’t miss out on the popular points of interest that South America has to offer, start planning your next adventure by renting a South America Midsize car today! ## Midsize Car Hire Information | Car type: | Midsize | | ------------------------------- | --------------------------------------------------------------------------------------------------------- | | From the airport to your hotel: | [Airport Transportation](https://www.expedia.co.uk/ground-transfers?rfrr=car.table.AirportTransportation) | ### Experience new places with Expedia See our world of travel options ### Expedia's Latest Trends Hotels - [All-Inclusive Hotels in Brazil](https://expedia.co.uk/Destinations-In-Brazil-All-Inclusive-Hotel.0-0-d23-tAllInclusiveHotel.Hotel-Filter-Destinations) - [All-Inclusive Hotels in Rio de Janeiro State](https://expedia.co.uk/Destinations-In-Rio-De-Janeiro-State-All-Inclusive-Hotel.0-0-d6052641-tAllInclusiveHotel.Hotel-Filter-Destinations) - [Hotels in Brazil](https://expedia.co.uk/Destinations-In-Brazil.d23.Hotel-Destinations) - [Hotels in Guyana](https://expedia.co.uk/Destinations-In-Guyana.d74.Hotel-Destinations) - [All-Inclusive Hotels in Colombia](https://expedia.co.uk/Destinations-In-Colombia-All-Inclusive-Hotel.0-0-d38-tAllInclusiveHotel.Hotel-Filter-Destinations) Flights - [Flights to Argentina](https://expedia.co.uk/Destinations-In-Argentina.d8.Flight-Destinations) - [Flights to Falkland Islands](https://expedia.co.uk/Destinations-In-Falkland-Islands.d11711.Flight-Destinations) - [Flights to Brazil](https://expedia.co.uk/Destinations-In-Brazil.d23.Flight-Destinations) - [Flights to Colombia](https://expedia.co.uk/Destinations-In-Colombia.d38.Flight-Destinations) - [Flights to Bolivia](https://expedia.co.uk/Destinations-In-Bolivia.d21.Flight-Destinations) - [Flights to Guyana](https://expedia.co.uk/Destinations-In-Guyana.d74.Flight-Destinations) - [Flights to Uruguay](https://expedia.co.uk/Destinations-In-Uruguay.d191.Flight-Destinations) - [Flights to Galápagos](https://expedia.co.uk/Destinations-In-Galapagos.d1371.Flight-Destinations) - [Flights to Ecuador](https://expedia.co.uk/Destinations-In-Ecuador.d51.Flight-Destinations) - [Flights to Chile](https://expedia.co.uk/Destinations-In-Chile.d36.Flight-Destinations) - [Cheap Flights to Amazon Jungle](https://expedia.co.uk/Cheap-Flights-To-Amazon-Jungle.d3000655735.Travel-Guide-Flights) - [Flights to Peru](https://expedia.co.uk/Destinations-In-Peru.d144.Flight-Destinations) - [Cheap Flights to Ascension Island](https://expedia.co.uk/Cheap-Flights-To-Ascension-Island.d6047027.Travel-Guide-Flights) - [Flights to Suriname](https://expedia.co.uk/Destinations-In-Suriname.d171.Flight-Destinations) - [Cheap Flights to Tristan da Cunha](https://expedia.co.uk/Cheap-Flights-To-Tristan-Da-Cunha.d6035222.Travel-Guide-Flights) Packages - [Falkland Islands Holidays](https://expedia.co.uk/Falkland-Islands.d11711.Holidays-City-Breaks) - [Colombia Holidays](https://expedia.co.uk/Colombia.d38.Holidays-City-Breaks) - [Brazil Holidays](https://expedia.co.uk/Brazil.d23.Holidays-City-Breaks) - [Argentina Holidays](https://expedia.co.uk/Argentina.d8.Holidays-City-Breaks) - [St. Helena Holidays](https://expedia.co.uk/St-Helena.d11721.Holidays-City-Breaks) - [Peru Holidays](https://expedia.co.uk/Peru.d144.Holidays-City-Breaks) - [Galápagos Holidays](https://expedia.co.uk/Galapagos.d1371.Holidays-City-Breaks) - [Guyana Holidays](https://expedia.co.uk/Guyana.d74.Holidays-City-Breaks) - [Chile Holidays](https://expedia.co.uk/Chile.d36.Holidays-City-Breaks) - [Ascension Island Holidays](https://expedia.co.uk/Ascension-Island.d6047027.Holidays-City-Breaks)