Title: Midsize Santa Cruz Island Car Hire | Expedia.co.uk ![](https://images.trvl-media.com/place/738889999009755136/4c3b3ccf-779c-4a49-b298-480a0be8b464.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Midsize Car Hire Companies in Santa Cruz Island Photo by RebeccasRoutes ## Find Cheap Midsize Car Deals for Santa Cruz Island \* Price found within the past 6 days. Click for updated prices. ### Don't see what you're looking for? See all car hire in Santa Cruz Island [View all cars](https://expedia.co.uk/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Santa%20Cruz%20Island,%20Gal%C3%A1pagos,%20Ecuador&dpln=6053670&date1=04/11/2025&date2=06/11/2025&crfrr=defaultFlex&SearchType=Place&selCC=[%22midsize%22]) ## Midsize Car Hire Information | Car type: | Midsize | | --- | --- | | From the airport to your hotel: | [Airport Transportation](https://www.expedia.co.uk/ground-transfers?rfrr=car.table.AirportTransportation) | ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - [1 Star Hotels in Santa Fe Island](https://www.expedia.co.uk/1Star-Santa-Fe-Island-Hotels.s10-0-d6336630.Travel-Guide-Filter-Hotels) - [2 Star Hotels in Santa Fe Island](https://www.expedia.co.uk/2Star-Santa-Fe-Island-Hotels.s20-0-d6336630.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Santa Fe Island](https://www.expedia.co.uk/3Star-Santa-Fe-Island-Hotels.s30-0-d6336630.Travel-Guide-Filter-Hotels) - [4 Star Hotels in North Seymour Island](https://www.expedia.co.uk/4Star-North-Seymour-Island-Hotels.s40-0-d6336659.Travel-Guide-Filter-Hotels) - [4 Star Hotels in Santa Fe Island](https://www.expedia.co.uk/4Star-Santa-Fe-Island-Hotels.s40-0-d6336630.Travel-Guide-Filter-Hotels) - [5 Star Hotels in North Seymour Island](https://www.expedia.co.uk/5Star-North-Seymour-Island-Hotels.s50-0-d6336659.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Santa Fe Island](https://www.expedia.co.uk/5Star-Santa-Fe-Island-Hotels.s50-0-d6336630.Travel-Guide-Filter-Hotels) - [Baltra Hotels](https://www.expedia.co.uk/Baltra-Hotels.d6223000.Travel-Guide-Hotels) - [Bartolome Island Hotels](https://www.expedia.co.uk/Bartolome-Island-Hotels.d6336382.Travel-Guide-Hotels) - [Bellavista Hotels](https://www.expedia.co.uk/Bellavista-Hotels.d6342722.Travel-Guide-Hotels) - [Hotels near Charles Darwin Research Station](https://www.expedia.co.uk/Charles-Darwin-Research-Station-Hotels.0-l6171312-0.Travel-Guide-Filter-Hotels) - [Beach Resorts & in Galápagos](https://www.expedia.co.uk/Destinations-In-Galapagos-Beach-Hotels.0-0-d1371-tBeachHotels.Hotel-Filter-Destinations) - [Cheap Hotels in Galápagos](https://www.expedia.co.uk/Destinations-In-Galapagos-Budget-Hotels.0-0-d1371-tBudgetHotels.Hotel-Filter-Destinations) - [Family-Friendly Hotels in Galápagos](https://www.expedia.co.uk/Destinations-In-Galapagos-Family-Friendly-Hotel.0-0-d1371-tFamilyFriendlyHotel.Hotel-Filter-Destinations) - [Gay-Friendly Hotels in Galápagos](https://www.expedia.co.uk/Destinations-In-Galapagos-Gay-Friendly-Hotel.0-0-d1371-tGayFriendlyHotel.Hotel-Filter-Destinations) - [Hotels with Babysitting Services in Galápagos](https://www.expedia.co.uk/Destinations-In-Galapagos-Hotel-With-Babysitting-Services.0-0-d1371-thotelwithbabysittingservices.Hotel-Filter-Destinations) - [Hotels with Gym in Galápagos](https://www.expedia.co.uk/Destinations-In-Galapagos-Hotel-With-Gym.0-0-d1371-thotelwithgym.Hotel-Filter-Destinations) - [Luxury Hotels in Galápagos](https://www.expedia.co.uk/Destinations-In-Galapagos-Luxury-Hotel.0-0-d1371-tLuxuryHotel.Hotel-Filter-Destinations) - [Galápagos Hotels](https://www.expedia.co.uk/Destinations-In-Galapagos.d1371.Hotel-Destinations) - [El Cascajo Hotels](https://www.expedia.co.uk/El-Cascajo-Hotels.d6222749.Travel-Guide-Hotels) - [Cheap Hotels in North Seymour Island](https://www.expedia.co.uk/North-Seymour-Island-Hotels-Budget-Hotels.0-0-d6336659-tBudgetHotels.Travel-Guide-Filter-Hotels) - [Business Hotels in North Seymour Island](https://www.expedia.co.uk/North-Seymour-Island-Hotels-Business-Hotel.0-0-d6336659-tBusinessHotel.Travel-Guide-Filter-Hotels) - [Spa Hotels in North Seymour Island](https://www.expedia.co.uk/North-Seymour-Island-Hotels-Spa-Hotels.0-0-d6336659-tSpaHotels.Travel-Guide-Filter-Hotels) - [North Seymour Island Hotels](https://www.expedia.co.uk/North-Seymour-Island-Hotels.d6336659.Travel-Guide-Hotels) - [Puerto Ayora Hotels](https://www.expedia.co.uk/Puerto-Ayora-Hotels.d602686.Travel-Guide-Hotels) - [Rabida Island Hotels](https://www.expedia.co.uk/Rabida-Island-Hotels.d6336653.Travel-Guide-Hotels) - [Serviced Apartments in Santa Fe Island](https://www.expedia.co.uk/Santa-Fe-Island-Apart-Hotels.d6336630-aaApartHotels.Travel-Guide-Accommodation) - [B&B in Santa Fe Island](https://www.expedia.co.uk/Santa-Fe-Island-Bed-And-Breakfasts.d6336630-aaBedAndBreakfasts.Travel-Guide-Accommodation) - [Chalets in Santa Fe Island](https://www.expedia.co.uk/Santa-Fe-Island-Chalets.d6336630-aaChalets.Travel-Guide-Accommodation) - [Condo Rentals in Santa Fe Island](https://www.expedia.co.uk/Santa-Fe-Island-Condos.d6336630-aaCondos.Travel-Guide-Accommodation) - [Resorts in Santa Fe Island](https://www.expedia.co.uk/Santa-Fe-Island-Hotel-Resorts.d6336630-aaHotelResorts.Travel-Guide-Accommodation) - [Beach Resorts & in Santa Fe Island](https://www.expedia.co.uk/Santa-Fe-Island-Hotels-Beach-Hotels.0-0-d6336630-tBeachHotels.Travel-Guide-Filter-Hotels) - [Family-Friendly Hotels in Santa Fe Island](https://www.expedia.co.uk/Santa-Fe-Island-Hotels-Family-Friendly-Hotel.0-0-d6336630-tFamilyFriendlyHotel.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Santa Fe Island](https://www.expedia.co.uk/Santa-Fe-Island-Hotels-Pet-Friendly-Hotel.0-0-d6336630-tPetFriendlyHotel.Travel-Guide-Filter-Hotels) - [Santa Fe Island Hotels](https://www.expedia.co.uk/Santa-Fe-Island-Hotels.d6336630.Travel-Guide-Hotels) - [Villas in Santa Fe Island](https://www.expedia.co.uk/Santa-Fe-Island-Villas.d6336630-aaVillas.Travel-Guide-Accommodation) - [Santa Rosa Hotels](https://www.expedia.co.uk/Santa-Rosa-Hotels.d6053725.Travel-Guide-Hotels) - [Hotels near Seymour](https://www.expedia.co.uk/Seymour-Airport-Hotels.0-aGPS-0.Travel-Guide-Filter-Hotels) - [Flights to Baltra](https://www.expedia.co.uk/Cheap-Flights-To-Baltra.d6223000.Travel-Guide-Flights) - [Flights to Bartolome Island](https://www.expedia.co.uk/Cheap-Flights-To-Bartolome-Island.d6336382.Travel-Guide-Flights) - [Flights to Daphne Islands](https://www.expedia.co.uk/Cheap-Flights-To-Daphne-Islands.d6336492.Travel-Guide-Flights) - [Flights to North Seymour Island](https://www.expedia.co.uk/Cheap-Flights-To-North-Seymour-Island.d6336659.Travel-Guide-Flights) - [Flights to Puerto Ayora](https://www.expedia.co.uk/Cheap-Flights-To-Puerto-Ayora.d602686.Travel-Guide-Flights) - [Flights to Rabida Island](https://www.expedia.co.uk/Cheap-Flights-To-Rabida-Island.d6336653.Travel-Guide-Flights) - [Flights to Santa Fe Island](https://www.expedia.co.uk/Cheap-Flights-To-Santa-Fe-Island.d6336630.Travel-Guide-Flights) - [Flights to Seymour](https://www.expedia.co.uk/Cheap-Flights-To-Seymour.d6024439.Travel-Guide-Flights) - [Flights to Galápagos](https://www.expedia.co.uk/Destinations-In-Galapagos.d1371.Flight-Destinations) - [Flights from Seymour](https://www.expedia.co.uk/lp/airports/gps/flights-from-seymour-airport) - [Flights from Cartagena (CTG) to Isla Baltra (GPS)](https://www.expedia.co.uk/lp/flights/ctg/gps/cartagena-to-isla-baltra) - [Flights from Guayaquil (GYE) to Isla Baltra (GPS)](https://www.expedia.co.uk/lp/flights/gye/gps/guayaquil-to-isla-baltra) - [Flights from London (LGW) to Isla Baltra (GPS)](https://www.expedia.co.uk/lp/flights/lgw/gps/london-to-isla-baltra) - [Flights from London (LHR) to Isla Baltra (GPS)](https://www.expedia.co.uk/lp/flights/lhr/gps/london-to-isla-baltra) - [Flights from Manchester (MAN) to Isla Baltra (GPS)](https://www.expedia.co.uk/lp/flights/man/gps/manchester-to-isla-baltra) - [Flights from Miami (MIA) to Isla Baltra (GPS)](https://www.expedia.co.uk/lp/flights/mia/gps/miami-to-isla-baltra) - [Flights from Coca (OCC) to Isla Baltra (GPS)](https://www.expedia.co.uk/lp/flights/occ/gps/coca-to-isla-baltra) - [Flights from Santiago (SCL) to Isla Baltra (GPS)](https://www.expedia.co.uk/lp/flights/scl/gps/santiago-to-isla-baltra) - [Flights from Quito (UIO) to Isla Baltra (GPS)](https://www.expedia.co.uk/lp/flights/uio/gps/quito-to-isla-baltra) - [Baltra Holidays](https://www.expedia.co.uk/Baltra.d6223000.Holidays-City-Breaks) - [Bartolome Island Holidays](https://www.expedia.co.uk/Bartolome-Island.d6336382.Holidays-City-Breaks) - [Visit Bartolome Island](https://www.expedia.co.uk/Bartolome-Island.dx6336382) - [Charles Darwin Research Station](https://www.expedia.co.uk/Charles-Darwin-Research-Station-Galapagos.d6171312.Attraction) - [Visit El Cascajo](https://www.expedia.co.uk/El-Cascajo.dx6222749) - [Galápagos Holidays](https://www.expedia.co.uk/Galapagos.d1371.Holidays-City-Breaks) - [Visit Galápagos](https://www.expedia.co.uk/Galapagos.dx1371) - [Visit North Seymour Island](https://www.expedia.co.uk/North-Seymour-Island.dx6336659) - [Playa de los Alemanes](https://www.expedia.co.uk/Playa-De-Los-Alemanes-Puerto-Ayora.d553248625325955800.Attraction) - [Puerto Ayora Holidays](https://www.expedia.co.uk/Puerto-Ayora.d602686.Holidays-City-Breaks) - [Visit Puerto Ayora](https://www.expedia.co.uk/Puerto-Ayora.dx602686) - [Rabida Island Holidays](https://www.expedia.co.uk/Rabida-Island.d6336653.Holidays-City-Breaks) - [Visit Rabida Island](https://www.expedia.co.uk/Rabida-Island.dx6336653) - [Visit Santa Fe Island](https://www.expedia.co.uk/Santa-Fe-Island.dx6336630) - [Visit Santa Rosa](https://www.expedia.co.uk/Santa-Rosa.dx6053725) - [Tortuga Bay Beach](https://www.expedia.co.uk/Tortuga-Bay-Beach-Bella-Vista.d6171324.Attraction) - [Golf Holiday Packages Santa Fe Island](https://www.expedia.co.uk/lp/theme-holidays/golf-holidays/6336630/Santa-Fe-Island) - [Addcar rental Rental Cars in Bartolome Island](https://www.expedia.co.uk/AddCar-Rental-Car-Rentals-In-Bartolome-Island.d6336382-c1002.Car-Rental-Guide-Suppliers) - [Advantage Rent-A-Car Rental Cars in North Seymour Island](https://www.expedia.co.uk/Advantage-Rent-A-Car-Car-Rentals-In-North-Seymour-Island.d6336659-c3.Car-Rental-Guide-Suppliers) - [Apex Car Rentals Rental Cars in North Seymour Island](https://www.expedia.co.uk/Apex-Car-Rentals-Car-Rentals-In-North-Seymour-Island.d6336659-c1064.Car-Rental-Guide-Suppliers) - [Avis Rental Cars in North Seymour Island](https://www.expedia.co.uk/Avis-Car-Rentals-In-North-Seymour-Island.d6336659-c41.Car-Rental-Guide-Suppliers) - [Buchbinder Rental Cars in Bartolome Island](https://www.expedia.co.uk/Buchbinder-Car-Rentals-In-Bartolome-Island.d6336382-c1011.Car-Rental-Guide-Suppliers) - [Car hire Puerto Ayora](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Puerto-Ayora.d602686.Car-Hire-Guide) - [Rental cars Seymour airport](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Seymour.d6024439.Car-Hire-Guide) - [Car hire near Galápagos](https://www.expedia.co.uk/Destinations-In-Galapagos.d1371.Car-Hire-Destinations) - [Express Travel Group Rental Cars in Bartolome Island](https://www.expedia.co.uk/Express-Travel-Group-Car-Rentals-In-Bartolome-Island.d6336382-c1124.Car-Rental-Guide-Suppliers) - [Get Your Car Rental Cars in Santa Fe Island](https://www.expedia.co.uk/Get-Your-Car-Car-Rentals-In-Santa-Fe-Island.d6336630-c1120.Car-Rental-Guide-Suppliers) - [Greenmotion Rental Cars in North Seymour Island](https://www.expedia.co.uk/Greenmotion-Car-Rentals-In-North-Seymour-Island.d6336659-c1093.Car-Rental-Guide-Suppliers) - [Island Car Rentals Rental Cars in Santa Fe Island](https://www.expedia.co.uk/Island-Car-Rentals-Car-Rentals-In-Santa-Fe-Island.d6336630-c1132.Car-Rental-Guide-Suppliers) - [National Car Rental Rental Cars in Daphne Islands](https://www.expedia.co.uk/National-Car-Rental-Car-Rentals-In-Daphne-Islands.d6336492-c42.Car-Rental-Guide-Suppliers) - [Priceless Car Rental Rental Cars in Daphne Islands](https://www.expedia.co.uk/Priceless-Car-Rental-Car-Rentals-In-Daphne-Islands.d6336492-c1060.Car-Rental-Guide-Suppliers) - [Rent A Wreck Rental Cars in Daphne Islands](https://www.expedia.co.uk/Rent-A-Wreck-Car-Rentals-In-Daphne-Islands.d6336492-c33.Car-Rental-Guide-Suppliers) - [Surprice Car Rentals Rental Cars in North Seymour Island](https://www.expedia.co.uk/SurPrice-Car-Rentals-Car-Rentals-In-North-Seymour-Island.d6336659-c1034.Car-Rental-Guide-Suppliers) - [Thrifty Car Rental Rental Cars in North Seymour Island](https://www.expedia.co.uk/Thrifty-Car-Rental-Car-Rentals-In-North-Seymour-Island.d6336659-c45.Car-Rental-Guide-Suppliers) - [Top Rent a Car Rental Cars in Daphne Islands](https://www.expedia.co.uk/Top-Rent-A-Car-Car-Rentals-In-Daphne-Islands.d6336492-c1028.Car-Rental-Guide-Suppliers) - [Baltra Holiday Rentals](https://www.expedia.co.uk/Baltra-Holiday-Rentals.d6223000.Travel-Guide-HolidayRentals) - [Bellavista Holiday Rentals](https://www.expedia.co.uk/Bellavista-Holiday-Rentals.d6342722.Travel-Guide-HolidayRentals) - [Galápagos Holiday Rentals](https://www.expedia.co.uk/Destinations-In-Galapagos.d1371.Holiday-Rental-Destinations) - [Santa Rosa Holiday Rentals](https://www.expedia.co.uk/Santa-Rosa-Holiday-Rentals.d6053725.Travel-Guide-HolidayRentals) - [Things to do in Baltra](https://www.expedia.co.uk/Things-To-Do-In-Baltra.d6223000.Travel-Guide-Activities) - [Things to do in Galápagos](https://www.expedia.co.uk/Things-To-Do-In-Galapagos.d1371.Travel-Guide-Activities) - [Things to do in North Seymour Island](https://www.expedia.co.uk/Things-To-Do-In-North-Seymour-Island.d6336659.Travel-Guide-Activities) - [Things to do in Puerto Ayora](https://www.expedia.co.uk/Things-To-Do-In-Puerto-Ayora.d602686.Travel-Guide-Activities)