Title: Hotels in Mesopotamia - Best Mesopotamia Hotels from £44 - Fully Refundable Options - Expedia.co.uk [Mesopotamia Travel Guide](https://expedia.co.uk/Mesopotamia.dx6335336)[Holiday Rentals in Mesopotamia](https://expedia.co.uk/Mesopotamia-Holiday-Rentals.d6335336.Travel-Guide-HolidayRentals)[Flights to Mesopotamia](https://expedia.co.uk/Cheap-Flights-To-Mesopotamia.d6335336.Travel-Guide-Flights)[Mesopotamia Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Mesopotamia.d6335336.Car-Hire-Guide)[Mesopotamia Holidays](https://expedia.co.uk/Mesopotamia.d6335336.Holidays-City-Breaks) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Mesopotamia from £44 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [18 Dec - 19 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6335336&startDate=2025-12-18&endDate=2025-12-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [19 Dec - 20 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6335336&startDate=2025-12-19&endDate=2025-12-20&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [19 Dec - 21 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6335336&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [26 Dec - 28 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6335336&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Mesopotamia hotels ![Interior](https://images.trvl-media.com/lodging/101000000/100780000/100775800/100775775/68e1bf42.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Economy Double Room | In-room safe, blackout curtains, soundproofing, free WiFi](https://images.trvl-media.com/lodging/101000000/100780000/100775800/100775775/3bf33702.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/101000000/100780000/100775800/100775775/293745cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/101000000/100780000/100775800/100775775/d97c5d69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### To Spiti tis Sofias [](https://www.expedia.co.uk/Kastoria-Hotels-To-Spiti-Tis-Sofias.h100775775.Hotel-Information) Kastoria 10/10 Exceptional (1) "Tout simplement le meilleur de notre voyage en Grèce. Simple mais tellement mieux qu'ailleurs. Accueil parfait, chambre confortable et petit déjeuner de roi. Je reviendrais à 100% si je passe dans le coin. " ![France](https://a.travel-assets.com/egds/marks/flags/fr.svg) Anonymous traveller £57 includes taxes & fees 14 Jan - 15 Jan 2026 [](https://www.expedia.co.uk/Kastoria-Hotels-To-Spiti-Tis-Sofias.h100775775.Hotel-Information) ![Room amenity](https://images.trvl-media.com/lodging/75000000/74430000/74421200/74421141/9efd4fc6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/75000000/74430000/74421200/74421141/7e96622b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/75000000/74430000/74421200/74421141/d1622ff4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Double Room | Free WiFi](https://images.trvl-media.com/lodging/75000000/74430000/74421200/74421141/21b5c138.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Guesthouse Monopati [](https://www.expedia.co.uk/Amyntaio-Hotels-Guesthouse-Monopati.h74421141.Hotel-Information) Amyntaio 10/10 Exceptional (3) [](https://www.expedia.co.uk/Amyntaio-Hotels-Guesthouse-Monopati.h74421141.Hotel-Information) ![Egyptian cotton sheets, premium bedding, down duvets, pillow-top beds](https://images.trvl-media.com/lodging/5000000/4800000/4791800/4791757/9ba540ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/5000000/4800000/4791800/4791757/72de18d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite | Egyptian cotton sheets, premium bedding, down duvets, pillow-top beds](https://images.trvl-media.com/lodging/5000000/4800000/4791800/4791757/de93186f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4800000/4791800/4791757/3ebef3e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Kyknos De Luxe Hotel [](https://www.expedia.co.uk/Kastoria-Hotels-Kyknos-De-Luxe-Hotel.h4791757.Hotel-Information) Kastoria 10/10 Exceptional (43) "Very nice clean, very polite staff and great breakfast!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Vasilios £78 includes taxes & fees 13 Jan - 14 Jan 2026 [](https://www.expedia.co.uk/Kastoria-Hotels-Kyknos-De-Luxe-Hotel.h4791757.Hotel-Information) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/5000000/4970000/4967200/4967133/42ff45d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property – evening/night](https://images.trvl-media.com/lodging/5000000/4970000/4967200/4967133/7b18d73a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/5000000/4970000/4967200/4967133/bf0edcd5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/5000000/4970000/4967200/4967133/9770bd8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Esperos Palace Luxury & Spa Hotel [](https://www.expedia.co.uk/Kastoria-Hotels-Esperos-Palace-Luxury-Spa-Hotel.h4967133.Hotel-Information) Kastoria 9.0/10 Wonderful (84) "The hotel is beautiful, large room with balcony. Grate bathroom, comfortable, the dinner is good ,however the breakfast was amazing. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michal [](https://www.expedia.co.uk/Kastoria-Hotels-Esperos-Palace-Luxury-Spa-Hotel.h4967133.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/20000000/19520000/19518600/19518575/154a1dd3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor banquet area](https://images.trvl-media.com/lodging/20000000/19520000/19518600/19518575/6e5f574e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/20000000/19520000/19518600/19518575/a1d4324f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Staircase](https://images.trvl-media.com/lodging/20000000/19520000/19518600/19518575/e21f5828.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Guest House Ilektra [](https://www.expedia.co.uk/Voio-Hotels-Guest-House-Ilektra.h19518575.Hotel-Information) Voio 9.6/10 Exceptional (9) "Wonderful views, easy to find, spacious rooms, and great hospitality." ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Maria £52 includes taxes & fees 19 Dec - 20 Dec [](https://www.expedia.co.uk/Voio-Hotels-Guest-House-Ilektra.h19518575.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/13000000/12330000/12320100/12320036/w6487h5400x7y9-009caa8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/13000000/12330000/12320100/12320036/f76ef39a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property – evening/night](https://images.trvl-media.com/lodging/13000000/12330000/12320100/12320036/5972a4f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/13000000/12330000/12320100/12320036/18af8a49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Calma Hotel & Spa [](https://www.expedia.co.uk/Kastoria-Hotels-Calma-Hotel-Spa.h12320036.Hotel-Information) Kastoria 9.6/10 Exceptional (35) "Pleasant stay. Good amenities. Great staff. " ![New Zealand](https://a.travel-assets.com/egds/marks/flags/nz.svg) Robert [](https://www.expedia.co.uk/Kastoria-Hotels-Calma-Hotel-Spa.h12320036.Hotel-Information) ![3 restaurants, breakfast, lunch, dinner served; Greek cuisine ](https://images.trvl-media.com/lodging/14000000/13240000/13236700/13236658/009cc717.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Turkish bath/hammam, body treatments, hot stone massages](https://images.trvl-media.com/lodging/14000000/13240000/13236700/13236658/ae63993e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/14000000/13240000/13236700/13236658/69491c8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Suite, Lake View | Minibar, in-room safe, desk, soundproofing](https://images.trvl-media.com/lodging/14000000/13240000/13236700/13236658/c6af0d88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Limneon Resort & Spa [](https://www.expedia.co.uk/Kastoria-Hotels-Limneon-Resort-Spa.h13236658.Hotel-Information) Kastoria 9.2/10 Wonderful (197) "Wonderful stay. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Konstantinos £84 includes taxes & fees 11 Jan - 12 Jan 2026 [](https://www.expedia.co.uk/Kastoria-Hotels-Limneon-Resort-Spa.h13236658.Hotel-Information) ![Garden](https://images.trvl-media.com/lodging/19000000/18340000/18331700/18331611/61d57c32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/19000000/18340000/18331700/18331611/0c4bcaa5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/19000000/18340000/18331700/18331611/1ea5ff90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Room, Lake View | Individually decorated, soundproofing, free WiFi, bed sheets](https://images.trvl-media.com/lodging/19000000/18340000/18331700/18331611/ab54e263.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Guesthouse Vissinokipos [](https://www.expedia.co.uk/Kastoria-Hotels-Guesthouse-Vissinokipos.h18331611.Hotel-Information) Kastoria 9.4/10 Exceptional (10) "Wonderfull view and very friendly people.the place is avery dpecial artistic decorated.wonderfull weather.nice varieties for breakfast.price was ver good.i recommend it!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carmen [](https://www.expedia.co.uk/Kastoria-Hotels-Guesthouse-Vissinokipos.h18331611.Hotel-Information) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/4000000/3590000/3580400/3580393/37147189.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/4000000/3590000/3580400/3580393/2900e7a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property – evening/night](https://images.trvl-media.com/lodging/4000000/3590000/3580400/3580393/61858d6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Suite, Lake View | Living area | LED TV](https://images.trvl-media.com/lodging/4000000/3590000/3580400/3580393/da0670f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Chloe Hotel [](https://www.expedia.co.uk/Kastoria-Hotels-Chloe-Hotel.h3580393.Hotel-Information) Kastoria 10/10 Exceptional (86) "We enjoyed the stay, friendly staff and nice breakfast " ![Australia](https://a.travel-assets.com/egds/marks/flags/au.svg) Fani £83 includes taxes & fees 19 Dec - 20 Dec [](https://www.expedia.co.uk/Kastoria-Hotels-Chloe-Hotel.h3580393.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/13000000/12330000/12320100/12320031/1a61bc01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/13000000/12330000/12320100/12320031/9ba64b24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/13000000/12330000/12320100/12320031/cb9be105.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Twin Room | Minibar, in-room safe, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/13000000/12330000/12320100/12320031/030d9c88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Anesis Hotel [](https://www.expedia.co.uk/Kastoria-Hotels-Anesis-Hotel.h12320031.Hotel-Information) Kastoria 9.0/10 Wonderful (9) "Fantastic hotel in the heart of Kastoria. The owners are lovely people, very helpful and made me feel right at home. Will definitely stay there again!" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Adam £44 includes taxes & fees 13 Jan - 14 Jan 2026 [](https://www.expedia.co.uk/Kastoria-Hotels-Anesis-Hotel.h12320031.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/89000000/88290000/88283900/88283893/2c3bb5a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Economy Room | In-room safe, individually decorated, individually furnished](https://images.trvl-media.com/lodging/89000000/88290000/88283900/88283893/6496fadf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/89000000/88290000/88283900/88283893/faf466e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, individually decorated, individually furnished](https://images.trvl-media.com/lodging/89000000/88290000/88283900/88283893/60bdde4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Andromeda Boutique hotel [](https://www.expedia.co.uk/Kastoria-Hotels-Andromeda-Boutique-Hotel.h88283893.Hotel-Information) Kastoria 8.8/10 Excellent (3) [](https://www.expedia.co.uk/Kastoria-Hotels-Andromeda-Boutique-Hotel.h88283893.Hotel-Information) ![House | 2 bedrooms](https://images.trvl-media.com/lodging/124000000/123540000/123533000/123532946/c7834e8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House | 2 bedrooms](https://images.trvl-media.com/lodging/124000000/123540000/123533000/123532946/42bad698.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House | 2 bedrooms](https://images.trvl-media.com/lodging/124000000/123540000/123533000/123532946/1f96f842.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House | 2 bedrooms](https://images.trvl-media.com/lodging/124000000/123540000/123533000/123532946/4fc08fe1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Anastasia s Kastoria Cozy Modern Garden Retreat [](https://www.expedia.co.uk/Kastoria-Hotels-Anastasia-S-Kastoria-Cozy-Modern-Garden-Retreat.h123532946.Hotel-Information) Kastoria £106 includes taxes & fees 21 Dec - 22 Dec [](https://www.expedia.co.uk/Kastoria-Hotels-Anastasia-S-Kastoria-Cozy-Modern-Garden-Retreat.h123532946.Hotel-Information) ![Apartment | 3 bedrooms, Internet](https://images.trvl-media.com/lodging/123000000/122570000/122560500/122560404/ef2afe04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | 3 bedrooms, Internet](https://images.trvl-media.com/lodging/123000000/122570000/122560500/122560404/8133e6cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | 3 bedrooms, Internet](https://images.trvl-media.com/lodging/123000000/122570000/122560500/122560404/da27481d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | 3 bedrooms, Internet](https://images.trvl-media.com/lodging/123000000/122570000/122560500/122560404/c74e29e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Sunset Haven Kastoria Modern Lake Elegance [](https://www.expedia.co.uk/Kastoria-Hotels-The-Sunset-Haven-Kastoria-Modern-Lake-Elegance.h122560404.Hotel-Information) Kastoria [](https://www.expedia.co.uk/Kastoria-Hotels-The-Sunset-Haven-Kastoria-Modern-Lake-Elegance.h122560404.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-01&endDate=2026-01-02®ionId=6335336&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FMesopotamia-Hotels.d6335336.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FMesopotamia-Hotels.d6335336.Travel-Guide-Hotels) ## Top Mesopotamia Hotel Reviews ![Kyknos De Luxe Hotel](https://images.trvl-media.com/lodging/5000000/4800000/4791800/4791757/9ba540ac_y.jpg) ### Kyknos De Luxe Hotel 10/10 Excellent "The staff was warm and welcoming. The rooms were amazing and the breakfast was fantastic. Lots of ethnic Greek foods" [](https://expedia.co.uk/Kastoria-Hotels-Kyknos-De-Luxe-Hotel.h4791757.Hotel-Information) ![Limneon Resort & Spa](https://images.trvl-media.com/lodging/14000000/13240000/13236700/13236658/009cc717_y.jpg) ### Limneon Resort & Spa 10/10 Excellent "Excellent! " [](https://expedia.co.uk/Kastoria-Hotels-Limneon-Resort-Spa.h13236658.Hotel-Information) ![Orologopoulos Mansion](https://images.trvl-media.com/lodging/14000000/13380000/13370900/13370805/a88b51c3_y.jpg) ### Orologopoulos Mansion 10/10 Excellent "Wonderful stay Very well kept hotel Nice room with a warm feeling The spaces in hotel are beautiful and give you the feeling that you stay at a luxurious home Very good breakfast- I will definitely stay here again " [](https://expedia.co.uk/Kastoria-Hotels-Orologopoulos-Mansion.h13370805.Hotel-Information) ![Esperos Palace Luxury & Spa Hotel](https://images.trvl-media.com/lodging/5000000/4970000/4967200/4967133/42ff45d8_y.jpg) ### Esperos Palace Luxury & Spa Hotel 10/10 Excellent "The hotel is beautiful, large room with balcony. Grate bathroom, comfortable, the dinner is good ,however the breakfast was amazing. " [](https://expedia.co.uk/Kastoria-Hotels-Esperos-Palace-Luxury-Spa-Hotel.h4967133.Hotel-Information) ![Calma Hotel & Spa](https://images.trvl-media.com/lodging/13000000/12330000/12320100/12320036/w6487h5400x7y9-009caa8e_y.jpg) ### Calma Hotel & Spa 10/10 Excellent "Pleasant stay. Good amenities. Great staff. " [](https://expedia.co.uk/Kastoria-Hotels-Calma-Hotel-Spa.h12320036.Hotel-Information) ![Chloe Hotel](https://images.trvl-media.com/lodging/4000000/3590000/3580400/3580393/37147189_y.jpg) ### Chloe Hotel 10/10 Excellent "Romantic and special. Highly recommend. Kastoria is a rare find. This hotel is a great getaway. " [](https://expedia.co.uk/Kastoria-Hotels-Chloe-Hotel.h3580393.Hotel-Information) ![Hotel Anastassiou](https://images.trvl-media.com/lodging/7000000/6140000/6136500/6136437/92fd8775_y.jpg) ### Hotel Anastassiou 8/10 Good "Nice simple stay." [](https://expedia.co.uk/Kastoria-Hotels-Hotel-Anastassiou.h6136437.Hotel-Information) ## More cheap stays in Mesopotamia ![Anesis Hotel](https://images.trvl-media.com/lodging/13000000/12330000/12320100/12320031/1a61bc01_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Anesis Hotel Grammou 10 Kastoria £44 13 Jan - 14 Jan 2026 includes taxes & fees [](https://expedia.co.uk/Kastoria-Hotels-Anesis-Hotel.h12320031.Hotel-Information) ![Hotel Anastassiou](https://images.trvl-media.com/lodging/7000000/6140000/6136500/6136437/92fd8775_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Anastassiou 1st km Highway Kastoria-Athens Kastoria Western Macedonia [Get rates](https://expedia.co.uk/Hotel-Search?startDate=01%2F01%2F2026&endDate=02%2F01%2F2026&selected=6136437&PinnedHotelID=6136437&HadPinnedHotel=true®ionId=6335336) 7.8/10 Good! (69 reviews) [](https://expedia.co.uk/Kastoria-Hotels-Hotel-Anastassiou.h6136437.Hotel-Information) ![Arhontiko Christodoulou](https://images.trvl-media.com/lodging/37000000/36790000/36784300/36784216/99031f32_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Arhontiko Christodoulou vrontero Prespes [Get rates](https://expedia.co.uk/Hotel-Search?startDate=01%2F01%2F2026&endDate=02%2F01%2F2026&selected=36784216&PinnedHotelID=36784216&HadPinnedHotel=true®ionId=6335336) [](https://expedia.co.uk/Prespes-Hotels-Arhontiko-Christodoulou.h36784216.Hotel-Information) ## Find out more about Mesopotamia ### Top reasons to visit Mesopotamia - **Stunning Beaches:** Mesopotamia boasts beautiful beaches ideal for sunbathing and water sports, perfect for relaxation and enjoyment. - **Rich Cultural Heritage:** The area offers a chance to explore local museums and historical landmarks, immersing visitors in its vibrant history. - **Scenic Landscapes:** Enjoy picturesque picnic areas amidst breathtaking natural surroundings, perfect for leisurely afternoons. - **Diverse Accommodation:** From budget-friendly hotels to luxurious spa retreats, there's something for every traveller. - **Warm Hospitality:** Experience the friendly locals and their welcoming nature, enhancing your visit to this charming region. ### Find great hotels near Mesopotamia Discover a range of delightful hotels in Mesopotamia, Western Macedonia, perfect for your getaway. Whether you seek a friendly atmosphere or require business-themed amenities, you'll find a variety of options to suit your needs. Enjoy adventure or spa-themed experiences while staying in some of the top hotels in the area. Explore Expedia for the best Mesopotamia hotel deals and make your stay truly memorable. - **[Esperos Palace Luxury & Spa Hotel: ](https://www.expedia.co.uk/Kastoria-Hotels-Esperos-Palace-Luxury-Spa-Hotel.h4967133.Hotel-Information)** Experience the epitome of relaxation and business efficiency at the Esperos Palace Luxury & Spa Hotel, a distinguished 4-star accommodation located 3.1km from Mesopotamia. This property combines modern luxury with comprehensive business amenities, making it ideal for corporate travellers. Guests can take advantage of the Conference Centre and multiple meeting rooms, alongside a full-service spa offering body treatments and manicures to unwind after a busy day. The inviting pool service ensures a serene environment, perfect for rejuvenation amidst your travels. - **[Hotel Anastassiou: ](https://www.expedia.co.uk/Kastoria-Hotels-Hotel-Anastassiou.h6136437.Hotel-Information)** Embrace the thrill of adventure and business at Hotel Anastassiou, which is also situated 3.1km from Mesopotamia. This hotel is perfect for those seeking an active vacation, with proximity to ski lifts and a variety of adventure sports such as kayaking and snowboarding. The property caters to business needs with a dedicated Business Centre and meeting facilities. Combining adrenaline-pumping activities with business efficiency, this hotel offers a unique blend for those who want to balance work with play. - **[Kyknos De Luxe Hotel: ](https://www.expedia.co.uk/Kastoria-Hotels-Kyknos-De-Luxe-Hotel.h4791757.Hotel-Information)** The Kyknos De Luxe Hotel, a 3.5-star establishment located 3.1km from Mesopotamia, promises a luxurious stay for discerning travellers. With a focus on both comfort and business, this hotel features essential services for professionals on the go. The elegant accommodations provide a tranquil retreat after a busy day, making it perfect for those seeking a refined and sophisticated atmosphere. The blend of luxury and practicality makes Kyknos De Luxe a compelling choice for a memorable stay. ### Where to stay near Mesopotamia Mesopotamia, a charming village in Western Macedonia, Greece, offers a delightful mix of outdoor adventures and rich cultural experiences. Ideal for romantic getaways or family-friendly holidays, visitors can explore the scenic landscapes and enjoy the warm hospitality of the locals. Nearby attractions also feature trendy cafés and luxury accommodations, ensuring a memorable stay. Don't miss the vibrant Akitu celebration, which showcases the region's unique traditions and festive spirit, making it a perfect holiday destination. - **[Kastoria: ](https://www.expedia.co.uk/Kastoria-Hotels.d1928.Travel-Guide-Hotels)** Nestled approximately 3.1km from Mesopotamia, Kastoria is a picturesque city renowned for its stunning natural beauty and rich history. The city sees a steady influx of visitors, particularly peaking in September and during the winter months of November to December. Adventurers and outdoor enthusiasts flock here to experience the breathtaking scenery and partake in activities such as skiing and spa treatments. Kastoria is also home to captivating landmarks, including historic sites, charming monasteries, and majestic mountains, making it an ideal destination for those looking to blend relaxation with adventure. - **[Árgos Orestikón: ](https://www.expedia.co.uk/Argos-Orestikon-Hotels.d3000031412.Travel-Guide-Hotels)** Located about 3.7km from Mesopotamia, Árgos Orestikón is a vibrant city that draws visitors seeking a culturally enriching experience. With visitor numbers peaking in September and during the festive months of December to January, this city offers a unique glimpse into the region's history and traditions. Explore local museums, places of worship, and archaeological sites that reveal the area's rich anthropological heritage. Árgos Orestikón is perfect for culture enthusiasts keen to immerse themselves in the local lifestyle and history. - **[Dispilio: ](https://www.expedia.co.uk/Dispilio-Hotels.d6335332.Travel-Guide-Hotels)** Situated 4.3km from Mesopotamia, the quaint village of Dispilio is a haven for those who enjoy winter sports and outdoor adventures. With a seasonal influx of visitors, particularly during the summer months of July to September, Dispilio is known for its ski resorts and adventure activities. The stunning nearby lake and beach offer a serene backdrop for relaxation, while local museums provide insight into the area's heritage. Whether you’re skiing in winter or enjoying the natural beauty in warmer months, Dispilio promises an unforgettable experience. ### Things to do in Mesopotamia Mesopotamia, nestled in the picturesque Kastoria region of Western Macedonia, Greece, is ideal for outdoor enthusiasts and couples seeking a romantic getaway steeped in culture. Visitors can take advantage of the local tour desk to explore the area's rich heritage, while the serene picnic area provides a perfect setting for a leisurely lunch amidst stunning landscapes. **Shopping** In Mesopotamia, you can visit local shops for unique souvenirs and traditional crafts. If you're up for a drive, head to the nearby city of Kastoria, where you can explore the beautiful Kastoria Shopping Centre with its variety of boutiques and artisan shops. **Recreation** In Mesopotamia, the Euphoria Wellness Retreat boasts tranquil surroundings, yoga sessions, and holistic therapies to rejuvenate your spirit. Nearby, the Thermal Springs offer soothing mineral baths, perfect for relaxation after a day of exploring the stunning landscapes of Western Macedonia. **Adventure** Explore the enchanting Mesopotamia River, perfect for kayaking or canoeing, offering an exhilarating experience amidst lush landscapes. For hiking enthusiasts, the nearby trails reveal stunning views and rich flora, making for an unforgettable adventure through this historic region of Western Macedonia. **Nightlife** Mesopotamia offers a vibrant nightlife with charming tavernas and lively bars. Enjoy a delicious meal at a local eatery before heading to Café Lotos for cocktails or the buzzing atmosphere at Night Club Velvet, where you can dance the night away with locals and fellow tourists alike. ### Booking tips and Expedia advantages for Mesopotamia To save money during your visit to Mesopotamia, consider travelling in March or October to November when prices are lower. Booking your hotel about a month in advance or taking advantage of last-minute deals on sites like Expedia can lead to significant savings. The cheapest day to stay is Monday, while Thursday tends to be the priciest. Use Expedia’s search tool to filter results by budget and hotel type, including eco-friendly options. Additionally, look for package deals that combine hotels, flights, and activities for further discounts. - **The most and least expensive months on average to stay in a hotel:** The cheapest months to stay in Mesopotamia are March and October to November, where the prices are slightly lower. This is in comparison to April and July to August, where prices are slightly higher. - **The best time to book a hotel:** Booking a hotel in Mesopotamia about 1 month out from when you are planning to stay is usually when prices are lowest. If you're a little more spontaneous, you could also peruse Expedia's last minute deals for hotels, look out for the green banner below the price, as this indicates a cheaper deal. - **The most and least expensive days on average to stay in a hotel:** The least expensive day to stay in Mesopotamia is Monday. The most expensive day to stay in Mesopotamia is Thursday. - **Find cheap hotels on Expedia:** Expedia’s search tool enables you to set your budget, choose your desired location, and much more. You can arrange your results to display prices from lowest to highest, allowing you to find the most affordable hotels first. Additionally, you have the option to refine your search by hotel type. For instance, selecting the Eco-certified filter will showcase sustainable and environmentally friendly hotels that are available for booking. - **Consider bundling your trip:** You can save money by combining your hotel reservations in Mesopotamia with your flights and activities through an Expedia package. ### Find the best attractions near Mesopotamia Mesopotamia, nestled in Western Macedonia, Greece, is perfect for outdoor, romantic, and culture-themed getaways. Visitors can explore a variety of attractions, including picturesque lakes, fascinating history museums, and iconic landmarks. This charming area caters to those seeking cultural enrichment, scenic beauty, and a relaxing beach experience. Consider taking a guided tour of Mesopotamia to fully appreciate its rich heritage and stunning landscapes. - **[Kastoria Lake: ](https://www.expedia.co.uk/Kastoria-Lake-Hotels.0-l553248621532501791-0.Travel-Guide-Filter-Hotels)** Nestled just 3.1km from Mesopotamia, Kastoria Lake offers stunning natural beauty with its serene waters and picturesque surroundings. Ideal for romantic strolls and outdoor activities, it's a perfect spot to unwind and connect with nature. - **Folklore Museum of Kastoria:** Located 3.1km from Mesopotamia, this museum immerses you in the rich cultural heritage of the region. With its diverse exhibits, you can explore the traditional crafts, costumes, and daily life of the local people, making it a fascinating cultural experience. - **Taxiarhia of the Metropolis:** Just 3.1km away, this landmark combines trendy aesthetics with a touch of luxury. Whether you're on a budget or looking to indulge, the surroundings offer a unique blend of history and modern charm, perfect for exploration. ### Best time to go to Mesopotamia The best time to visit Mesopotamia can depend on the weather and when visitor numbers rise and fall. The hottest average temperature in Mesopotamia falls in August, when visitor numbers are moderately high and weather is sunny with no rain (dry). The coolest average temperature in Mesopotamia falls in January, visitor numbers are moderately low and weather is mostly sunny with light rain. | **![calendar](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/calendar.png)Calendar Month** | **![temperature](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__hot.png)Temperature** | **![rain](https://forever.travel-assets.com/flex/flexmanager/images/2024/03/04/weather__rain.png)Precipitation** | **![mostly](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/weather__day_mostly_cloudy.png)Cloudiness** | **![occupation](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/peoplebex.png)Occupancy** | **![price](https://forever.travel-assets.com/flex/flexmanager/images/2024/10/29/currency_dollar.png)Pricing** | | ---------------------------------------------------------------------------------------------------------------- | -------------------------------------------------------------------------------------------------------------------- | ---------------------------------------------------------------------------------------------------------------- | ---------------------------------------------------------------------------------------------------------------------------- | -------------------------------------------------------------------------------------------------------------- | ------------------------------------------------------------------------------------------------------------- | | January | 32.5°F (0.3°C) | Light Rain | Mostly Sunny | Moderately Low | Slightly Low | | February | 36.1°F (2.3°C) | Light Rain | Mostly Sunny | Average | Slightly Low | | March | 41.7°F (5.4°C) | Light Rain | Mostly Sunny | Moderately Low | Average | | April | 50.2°F (10.1°C) | Light Rain | Mostly Sunny | Average | Slightly High | | May | 57.9°F (14.4°C) | Light Rain | Mostly Sunny | Moderately High | Average | | June | 66.0°F (18.9°C) | No Rain (Dry) | Mostly Sunny | Average | Average | | July | 72.3°F (22.4°C) | No Rain (Dry) | Sunny | Moderately High | Slightly High | | August | 72.5°F (22.5°C) | No Rain (Dry) | Sunny | Moderately High | Average | | September | 64.2°F (17.9°C) | No Rain (Dry) | Mostly Sunny | Average | Average | | October | 54.1°F (12.3°C) | Light Rain | Mostly Sunny | Average | Average | | November | 45.1°F (7.3°C) | Light Rain | Mostly Sunny | Moderately Low | Slightly Low | | December | 36.3°F (2.4°C) | Light Rain | Mostly Sunny | Average | Slightly High | ### The nearest major airports for your trip to Mesopotamia For your visit to Mesopotamia in Western Macedonia, Greece, you can choose between two major airports. Kozani Airport (KZI-Filippos), situated 23.6km away, has several hotel options including [Elimeia 3](https://www.expedia.co.uk/Kozani-Hotels-Elimeia-3.h21152987.Hotel-Information), which is 5.6km from the airport, and [Anesis Hotel](https://www.expedia.co.uk/Kozani-Hotels-Anesis-Hotel.h1516031.Hotel-Information), merely 1.2km away. Alternatively, Kastoria Airport (KSO-Aristoteles) is only 4.3km from Mesopotamia, with excellent nearby accommodations such as the luxurious [Limneon Resort & Spa](https://www.expedia.co.uk/Kastoria-Hotels-Limneon-Resort-Spa.h13236658.Hotel-Information), located 1.9km away, and the [Orologopoulos Mansion](https://www.expedia.co.uk/Kastoria-Hotels-Orologopoulos-Mansion.h13370805.Hotel-Information), 3.1km from the airport. Various transportation services are available, including free airport shuttles from some hotels near Kastoria. ## Frequently asked questions ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Mesopotamia hotel booking with Expedia? ### How much is the nightly rate at a Mesopotamia hotel? ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - [4 Star Hotels in Mouriki ](https://www.expedia.co.uk/4Star-Mouriki-Hotels.s40-0-d553248635976431739.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Kastoria ](https://www.expedia.co.uk/5Star-Kastoria-Hotels.s50-0-d1928.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Nymfaio ](https://www.expedia.co.uk/5Star-Nymfaio-Hotels.s50-0-d6335267.Travel-Guide-Filter-Hotels) - [Agios Achillios Hotels ](https://www.expedia.co.uk/Agios-Achillios-Hotels.d553248635975863261.Travel-Guide-Hotels) - [Agios Germanos Hotels ](https://www.expedia.co.uk/Agios-Germanos-Hotels.d6335344.Travel-Guide-Hotels) - [Agios Kosmas Hotels ](https://www.expedia.co.uk/Agios-Kosmas-Hotels.d3000476526.Travel-Guide-Hotels) - [Amyntaio Hotels ](https://www.expedia.co.uk/Amyntaio-Hotels.d6334813.Travel-Guide-Hotels) - [Antartiko Hotels ](https://www.expedia.co.uk/Antartiko-Hotels.d6335345.Travel-Guide-Hotels) - [Aposkepos Hotels ](https://www.expedia.co.uk/Aposkepos-Hotels.d6335331.Travel-Guide-Hotels) - [Árgos Orestikón Hotels ](https://www.expedia.co.uk/Argos-Orestikon-Hotels.d3000031412.Travel-Guide-Hotels) - [Florina Hotels ](https://www.expedia.co.uk/Florina-Hotels.d6024959.Travel-Guide-Hotels) - [Kaloneri Hotels ](https://www.expedia.co.uk/Kaloneri-Hotels.d3000389214.Travel-Guide-Hotels) - [Kastoria Hotels ](https://www.expedia.co.uk/Kastoria-Hotels.d1928.Travel-Guide-Hotels) - [Hotels near Kastoria Lake ](https://www.expedia.co.uk/Kastoria-Lake-Hotels.0-l553248621532501791-0.Travel-Guide-Filter-Hotels) - [Korisos Hotels ](https://www.expedia.co.uk/Korisos-Hotels.d6335334.Travel-Guide-Hotels) - [Laimos Hotels ](https://www.expedia.co.uk/Laimos-Hotels.d6335346.Travel-Guide-Hotels) - [Lefkandi Hotels ](https://www.expedia.co.uk/Lefkandi-Hotels.d3000396373.Travel-Guide-Hotels) - [Maniakoi Hotels ](https://www.expedia.co.uk/Maniakoi-Hotels.d3000702866.Travel-Guide-Hotels) - [Mesolourion Hotels ](https://www.expedia.co.uk/Mesolourion-Hotels.d6335291.Travel-Guide-Hotels) - [Nestorio Hotels ](https://www.expedia.co.uk/Nestorio-Hotels.d6345335.Travel-Guide-Hotels) - [Nymfaio Hotels ](https://www.expedia.co.uk/Nymfaio-Hotels.d6335267.Travel-Guide-Hotels) - [Poria Hotels ](https://www.expedia.co.uk/Poria-Hotels.d6335337.Travel-Guide-Hotels) - [Hotels near Prespa National Park ](https://www.expedia.co.uk/Prespa-National-Park-Hotels.0-l553248624894242165-0.Travel-Guide-Filter-Hotels) - [Prespes Hotels ](https://www.expedia.co.uk/Prespes-Hotels.d6334868.Travel-Guide-Hotels) - [Ptolemaida Hotels ](https://www.expedia.co.uk/Ptolemaida-Hotels.d6335276.Travel-Guide-Hotels) - [Samarina Hotels ](https://www.expedia.co.uk/Samarina-Hotels.d6240088.Travel-Guide-Hotels) - [Sidirochori Hotels ](https://www.expedia.co.uk/Sidirochori-Hotels.d6335338.Travel-Guide-Hotels) - [Tsotilion Hotels ](https://www.expedia.co.uk/Tsotilion-Hotels.d6335353.Travel-Guide-Hotels) - [Tsotyli Hotels ](https://www.expedia.co.uk/Tsotyli-Hotels.d3000475751.Travel-Guide-Hotels) - [Varikon Hotels ](https://www.expedia.co.uk/Varikon-Hotels.d6335271.Travel-Guide-Hotels) - [Vitsi Hotels ](https://www.expedia.co.uk/Vitsi-Hotels.d6334824.Travel-Guide-Hotels) - [Vlasti Hotels ](https://www.expedia.co.uk/Vlasti-Hotels.d6335281.Travel-Guide-Hotels) - [Voio Hotels ](https://www.expedia.co.uk/Voio-Hotels.d6334814.Travel-Guide-Hotels) - [Flights to Florina ](https://www.expedia.co.uk/Cheap-Flights-To-Florina.d6024959.Travel-Guide-Flights) - [Flights to Kastoria ](https://www.expedia.co.uk/Cheap-Flights-To-Kastoria.d1928.Travel-Guide-Flights) - [Flights to Mouriki ](https://www.expedia.co.uk/Cheap-Flights-To-Mouriki.d553248635976431739.Travel-Guide-Flights) - [Flights to Nymfaio ](https://www.expedia.co.uk/Cheap-Flights-To-Nymfaio.d6335267.Travel-Guide-Flights) - [Flights from Aristoteles ](https://www.expedia.co.uk/lp/airports/kso/flights-from-aristoteles-airport) - [Flights from Amyntaio ](https://www.expedia.co.uk/lp/flights/6334813/flights-from-amyntaio) - [Flights from Athens (ATH) to Kastoria (KSO) ](https://www.expedia.co.uk/lp/flights/ath/kso/athens-to-kastoria) - [Flights from Birmingham (BHX) to Kastoria (KSO) ](https://www.expedia.co.uk/lp/flights/bhx/kso/birmingham-to-kastoria) - [Flights from London (LHR) to Kastoria (KSO) ](https://www.expedia.co.uk/lp/flights/lhr/kso/london-to-kastoria) - [Agios Kosmas Holidays ](https://www.expedia.co.uk/Agios-Kosmas.d3000476526.Holidays-City-Breaks) - [Visit Agios Kosmas ](https://www.expedia.co.uk/Agios-Kosmas.dx3000476526) - [Visit Aminteo ](https://www.expedia.co.uk/Aminteo.dx3000476507) - [Byzantine Museum of Kastoria ](https://www.expedia.co.uk/Byzantine-Museum-Of-Kastoria-Kastoria.d6263517.Attraction) - [Eordaia Holidays ](https://www.expedia.co.uk/Eordaia.d6334970.Holidays-City-Breaks) - [Visit Eordaia ](https://www.expedia.co.uk/Eordaia.dx6334970) - [Visit Florina ](https://www.expedia.co.uk/Florina.dx6024959) - [Holy Prophet Elias Church ](https://www.expedia.co.uk/Holy-Prophet-Elias-Church-Kastoria.d553248635935219972.Attraction) - [Visit Kaloneri ](https://www.expedia.co.uk/Kaloneri.dx3000389214) - [Kastoria Holidays ](https://www.expedia.co.uk/Kastoria.d1928.Holidays-City-Breaks) - [Visit Kastoria ](https://www.expedia.co.uk/Kastoria.dx1928) - [Visit Lavda ](https://www.expedia.co.uk/Lavda.dx3000463532) - [Nestorio Holidays ](https://www.expedia.co.uk/Nestorio.d6345335.Holidays-City-Breaks) - [Visit Nestorio ](https://www.expedia.co.uk/Nestorio.dx6345335) - [Nymfaio Holidays ](https://www.expedia.co.uk/Nymfaio.d6335267.Holidays-City-Breaks) - [Polinerion Holidays ](https://www.expedia.co.uk/Polinerion.d6335294.Holidays-City-Breaks) - [Ptolemaida Holidays ](https://www.expedia.co.uk/Ptolemaida.d6335276.Holidays-City-Breaks) - [Visit Ptolemaida ](https://www.expedia.co.uk/Ptolemaida.dx6335276) - [Visit Samarina ](https://www.expedia.co.uk/Samarina.dx6240088) - [Visit Siatista ](https://www.expedia.co.uk/Siatista.dx6335352) - [Vitsi Holidays ](https://www.expedia.co.uk/Vitsi.d6334824.Holidays-City-Breaks) - [Vlasti Holidays ](https://www.expedia.co.uk/Vlasti.d6335281.Holidays-City-Breaks) - [Voio Holidays ](https://www.expedia.co.uk/Voio.d6334814.Holidays-City-Breaks) - [Visit Voio ](https://www.expedia.co.uk/Voio.dx6334814) - [Car hire Aetos ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Aetos.d6335261.Car-Hire-Guide) - [Car hire Florina ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Florina.d6024959.Car-Hire-Guide) - [Car hire Kastoria ](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Kastoria.d1928.Car-Hire-Guide) - [Vevi Holiday Rentals ](https://www.expedia.co.uk/Vevi-Holiday-Rentals.d6335283.Travel-Guide-HolidayRentals) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app