Title: Mesopotamia Holidays 2025 from £238 | Expedia.co.uk [Mesopotamia Travel Guide](https://expedia.co.uk/Mesopotamia.dx6335336)[Hotels in Mesopotamia](https://expedia.co.uk/Mesopotamia-Hotels.d6335336.Travel-Guide-Hotels)[Holiday Rentals in Mesopotamia](https://expedia.co.uk/Mesopotamia-Holiday-Rentals.d6335336.Travel-Guide-HolidayRentals)[Flights to Mesopotamia](https://expedia.co.uk/Cheap-Flights-To-Mesopotamia.d6335336.Travel-Guide-Flights)[Mesopotamia Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Mesopotamia.d6335336.Car-Hire-Guide) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_packages.jpeg?impolicy=fcrop&w=1200&h=300&q=medium) # Mesopotamia Holidays from £238 ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence ### Better together Save up to £335 when you book a flight and hotel together\* ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package ### Rest easy Packages with flights are ATOL protected #### Your Mesopotamia Holiday Our holiday packages to Mesopotamia let you create your own adventure. Tailor your getaway to your style and interests and make the most of your time in this wonderful city. Fill your schedule with tours of [Kastoria Lake](https://www.expedia.co.uk/Kastoria-Lake-Kastoria.d553248621532501791.Attraction), [Kastoria Aquarium](https://www.expedia.co.uk/Kastoria-Aquarium-Kastoria.d6334842.Attraction) and [Holy Prophet Elias Church](https://www.expedia.co.uk/Holy-Prophet-Elias-Church-Kastoria.d553248635935219972.Attraction), some of the top attractions you really should see during a trip to Mesopotamia. Your ideal Mesopotamia holiday is a few clicks away. Search airfares, hotels and more on Expedia for an adventure that's tailored to suit your style. ## Top Mesopotamia Flight + Hotel Deals Price found within the past 48 hours. Click for updated prices. ![Lazart Hotel, Trademark Collection by Wyndham](https://images.trvl-media.com/lodging/2000000/1280000/1273900/1273893/b42b9e8a_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Lazart Hotel, Trademark Collection by Wyndham Stavroupoli £238 per person 15 Jan - 18 Jan found 1 day ago Return direct flight included London (LGW) to Thessaloniki (SKG) 8.8/10 Excellent! (227 reviews) Lovely hotel, ideally located for our trip. Quick taxi to the main attractions of Thessaloniki. Would book again. Reviewed on 27 Sept 2025 [](https://expedia.co.uk/go/package/search/FlightHotel/2026-01-15/2026-01-18/?FromAirport=LGW&Destination=SKG&NumRoom=1&NumAdult=2&NumChild=0&hotelId=1273893&paandie=true&dealMarker=OVOzQV3ckHcuIFVneYzVPQ3Oq1xpP1A2FsPX0Dkr9O5XpHeGlzD76ohXOvaIR6h7) ![The Met Hotel, a member of Design Hotels](https://images.trvl-media.com/lodging/4000000/3040000/3034200/3034180/fec2fdc5_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### The Met Hotel, a member of Design Hotels Save 100% on your flight £408 per person 9 Dec - 14 Dec found 1 day ago Return flight included London (LHR) to Thessaloniki (SKG) 9.2/10 Wonderful! (843 reviews) The staff was amazingly kind and accommodating. Hotel was clean and smelled amazing. Appreciate the shuttle into the square. I look forward to coming back again! Reviewed on 22 Oct 2025 [](https://expedia.co.uk/go/package/search/FlightHotel/2025-12-09/2025-12-14/?FromAirport=LHR&Destination=SKG&NumRoom=1&NumAdult=2&NumChild=0&hotelId=3034180&paandie=true&dealMarker=7HOMWt2IhP3U1I4nS61q5IoabKpCipJpGtJ6_gQqnZwsYLKMOXAnm2tyxYeK0jCN) ![The Modernist Thessaloniki](https://images.trvl-media.com/lodging/24000000/23460000/23458400/23458330/ac78d3e5_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### The Modernist Thessaloniki Thessaloniki City Centre Save 100% on your flight £372 per person 9 Dec - 14 Dec found 1 day ago Return flight included London (LHR) to Thessaloniki (SKG) 9.8/10 Exceptional! (580 reviews) The staff couldn’t have been friendlier! Maria and Bobby were incredibly hospitable and helpful. I would definitely stay at The Modern again. Reviewed on 27 Oct 2025 [](https://expedia.co.uk/go/package/search/FlightHotel/2025-12-09/2025-12-14/?FromAirport=LHR&Destination=SKG&NumRoom=1&NumAdult=2&NumChild=0&hotelId=23458330&paandie=true&dealMarker=7HOMWt2IhP3U1I4nS61q5KeoY9G5KXz9VPHrJOcFmTiaO42_RluHb_06IaMmN22T) ![ON Residence](https://images.trvl-media.com/lodging/74000000/73780000/73771700/73771606/42be8aa2_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### ON Residence Thessaloniki City Centre Save 100% on your flight £407 per person 9 Dec - 14 Dec found 1 day ago Return flight included London (LHR) to Thessaloniki (SKG) 9.8/10 Exceptional! (152 reviews) This is the best hotel in town Reviewed on 16 Sept 2025 [](https://expedia.co.uk/go/package/search/FlightHotel/2025-12-09/2025-12-14/?FromAirport=LHR&Destination=SKG&NumRoom=1&NumAdult=2&NumChild=0&hotelId=73771606&paandie=true&dealMarker=7HOMWt2IhP3U1I4nS61q5IoabKpCipJpGtJ6_gQqnZyTIJbOWxxWJhn4sL_vUgw5) ![Daios Luxury Living](https://images.trvl-media.com/lodging/2000000/1580000/1570100/1570046/8ffaa44f_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Daios Luxury Living Thessaloniki City Centre Save 100% on your flight £439 per person 9 Dec - 14 Dec found 1 day ago Return flight included London (LHR) to Thessaloniki (SKG) 9.6/10 Exceptional! (748 reviews) Wonderful hotel. The room was like an apartment it was great. Really nice breakfast. Right on the ocean. Great location right im the action lots of food around there and shopping. Loved it! Reviewed on 20 Sept 2025 [](https://expedia.co.uk/go/package/search/FlightHotel/2025-12-09/2025-12-14/?FromAirport=LHR&Destination=SKG&NumRoom=1&NumAdult=2&NumChild=0&hotelId=1570046&paandie=true&dealMarker=7HOMWt2IhP3U1I4nS61q5IoabKpCipJpGtJ6_gQqnZxTCjOsjwqAO6LdbCRVhnAF) ## Mesopotamia Essential Information | Language | Greek | | --- | --- | | Currency | Euros | | Local Welcome | Ya su | | Local Goodbye | Yiá sou | | Closest Airport | Kastoria (KSO-Aristoteles) | | Population | 2,100 | | Max Temp Winter | 4ºC | | Max Temp Summer | 27ºC | | Top Sights | [Kastoria Aquarium](https://www.expedia.co.uk/Kastoria-Aquarium-Kastoria.d6334842.Attraction), [Folklore Museum of Kastoria](https://www.expedia.co.uk/Folklore-Museum-Of-Kastoria-Kastoria.d6263478.Attraction) and [Byzantine Museum of Kastoria](https://www.expedia.co.uk/Byzantine-Museum-Of-Kastoria-Kastoria.d6263517.Attraction) | ## Top hotels in Mesopotamia ![To Spiti tis Sofias](https://images.trvl-media.com/lodging/101000000/100780000/100775800/100775775/68e1bf42_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### To Spiti tis Sofias Mesopotamia, Kastoria, Western Macedonia Fully refundableReserve now, pay when you stay £57 12 Nov - 13 Nov includes taxes & fees 10/10 Exceptional! (1 review) Le meilleur de notre séjour Tout simplement le meilleur de notre voyage en Grèce. Simple mais tellement mieux qu'ailleurs. Accueil parfait, chambre confortable et petit déjeuner de roi. Je reviendrais à 100% si je passe dans le coin. Reviewed on 18 Aug 2025 [](https://expedia.co.uk/Hotel-Search?startDate=12%2F11%2F2025&endDate=13%2F11%2F2025&selected=100775775&PinnedHotelID=100775775&HadPinnedHotel=true®ionId=6335336) ![Limneon Resort & Spa](https://images.trvl-media.com/lodging/14000000/13240000/13236700/13236658/009cc717_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Limneon Resort & Spa 4th km National Road Kastoria Athens, Kastoria Fully refundableReserve now, pay when you stay £81 5 Nov - 6 Nov includes taxes & fees 9/10 Wonderful! (196 reviews) Excellent! Reviewed on 22 Sept 2025 [](https://expedia.co.uk/Hotel-Search?startDate=05%2F11%2F2025&endDate=06%2F11%2F2025&selected=13236658&PinnedHotelID=13236658&HadPinnedHotel=true®ionId=6335336) ![Esperos Palace Luxury & Spa Hotel](https://images.trvl-media.com/lodging/5000000/4970000/4967200/4967133/42ff45d8_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Esperos Palace Luxury & Spa Hotel Chloe Area, Kastoria, Western Macedonia Fully refundableReserve now, pay when you stay £86 2 Nov - 3 Nov includes taxes & fees 9/10 Wonderful! (84 reviews) The hotel is beautiful, large room with balcony. Grate bathroom, comfortable, the dinner is good ,however the breakfast was amazing. Reviewed on 4 Sept 2025 [](https://expedia.co.uk/Hotel-Search?startDate=02%2F11%2F2025&endDate=03%2F11%2F2025&selected=4967133&PinnedHotelID=4967133&HadPinnedHotel=true®ionId=6335336) [See all 41 properties in Mesopotamia](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=31%2F10%2F2025&endDate=01%2F11%2F2025®ionId=6335336) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Holidays [](https://expedia.co.uk/lp/theme-holidays/all-inclusive-holidays?rfrr=editorial.All_Inclusive%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Holidays [](https://expedia.co.uk/lp/theme-holidays/beach-holidays?rfrr=editorial.Beach_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Friendly Holidays [](https://expedia.co.uk/lp/theme-holidays/kid-friendly-holidays?rfrr=editorial.Family_Friendly%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Holidays [](https://expedia.co.uk/lp/theme-holidays/golf-holidays?rfrr=editorial.Golf_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Holidays [](https://expedia.co.uk/lp/theme-holidays/luxury-holidays?rfrr=editorial.Luxury_Holidays.click) ![gay friendly holidays](https://forever.travel-assets.com/flex/flexmanager/images/2023/06/15/LGBTQIA_Holiday_Package.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) LGBTQ+ Holidays [](https://expedia.co.uk/lp/theme-holidays/gay-friendly-holidays?rfrr=editorial.LGBTQ+_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Holidays [](https://expedia.co.uk/lp/theme-holidays/romantic-holidays?rfrr=editorial.Romantic_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Holidays [](https://expedia.co.uk/lp/theme-holidays/ski-holidays?rfrr=editorial.Ski_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/22/hero-image-pet-friendly_copy.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Pet Friendly Holidays [](https://expedia.co.uk/lp/theme-holidays/pet-friendly-holidays?rfrr=editorial.Pet_Friendly%20Holidays.click) ![Holiday in Month](https://forever.travel-assets.com/flex/flexmanager/images/2023/05/10/mesog-34434-card-venice.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Where to go when [](https://expedia.co.uk/lp/b/where-to-go-when?rfrr=editorial.Where_to%20go%20when.click) ### Popular places to visit #### Holy Prophet Elias Church After visiting Holy Prophet Elias Church, make a plan to see the other sights and activities in Kastoria. While you're in the area, stroll along the lakeside. [](https://expedia.co.uk/Holy-Prophet-Elias-Church-Kastoria.d553248635935219972.Attraction) #### Byzantine Museum of Kastoria You can spend an afternoon studying the exhibits at Byzantine Museum of Kastoria during your trip to Kastoria. While you're in the area, stroll along the lakeside. [](https://expedia.co.uk/Byzantine-Museum-Of-Kastoria-Kastoria.d6263517.Attraction) ### What to do in Mesopotamia ![Archery Odyssey Traditional Archery Experience](https://mediaim.expedia.com/localexpert/48403815/b4af75d6-0cec-4d50-a540-27608c144545.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Archery Odyssey Traditional Archery Experience £52 per adult [](https://expedia.co.uk/things-to-do/archery-odyssey-traditional-archery-experience.a48403815.activity-details) [See all activities in Mesopotamia](https://expedia.co.uk/things-to-do/search?rid=6335336) ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes ### Accommodation - [4 Star Hotels in Mouriki](https://www.expedia.co.uk/4Star-Mouriki-Hotels.s40-0-d553248635976431739.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Kastoria](https://www.expedia.co.uk/5Star-Kastoria-Hotels.s50-0-d1928.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Nymfaio](https://www.expedia.co.uk/5Star-Nymfaio-Hotels.s50-0-d6335267.Travel-Guide-Filter-Hotels) - 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[Kaloneri Hotels](https://www.expedia.co.uk/Kaloneri-Hotels.d3000389214.Travel-Guide-Hotels) - [Kastoria Hotels](https://www.expedia.co.uk/Kastoria-Hotels.d1928.Travel-Guide-Hotels) - [Hotels near Kastoria Lake](https://www.expedia.co.uk/Kastoria-Lake-Hotels.0-l553248621532501791-0.Travel-Guide-Filter-Hotels) - [Korisos Hotels](https://www.expedia.co.uk/Korisos-Hotels.d6335334.Travel-Guide-Hotels) - [Laimos Hotels](https://www.expedia.co.uk/Laimos-Hotels.d6335346.Travel-Guide-Hotels) - [Lavda Hotels](https://www.expedia.co.uk/Lavda-Hotels.d3000463532.Travel-Guide-Hotels) - [Lefkandi Hotels](https://www.expedia.co.uk/Lefkandi-Hotels.d3000396373.Travel-Guide-Hotels) - [Maniakoi Hotels](https://www.expedia.co.uk/Maniakoi-Hotels.d3000702866.Travel-Guide-Hotels) - [Mesolourion Hotels](https://www.expedia.co.uk/Mesolourion-Hotels.d6335291.Travel-Guide-Hotels) - [Nestorio Hotels](https://www.expedia.co.uk/Nestorio-Hotels.d6345335.Travel-Guide-Hotels) - [Nymfaio Hotels](https://www.expedia.co.uk/Nymfaio-Hotels.d6335267.Travel-Guide-Hotels) - [Polinerion Hotels](https://www.expedia.co.uk/Polinerion-Hotels.d6335294.Travel-Guide-Hotels) - [Poria Hotels](https://www.expedia.co.uk/Poria-Hotels.d6335337.Travel-Guide-Hotels) - [Hotels near Prespa National Park](https://www.expedia.co.uk/Prespa-National-Park-Hotels.0-l553248624894242165-0.Travel-Guide-Filter-Hotels) - [Prespes Hotels](https://www.expedia.co.uk/Prespes-Hotels.d6334868.Travel-Guide-Hotels) - [Ptolemaida Hotels](https://www.expedia.co.uk/Ptolemaida-Hotels.d6335276.Travel-Guide-Hotels) - [Samarina Hotels](https://www.expedia.co.uk/Samarina-Hotels.d6240088.Travel-Guide-Hotels) - [Siatista Hotels](https://www.expedia.co.uk/Siatista-Hotels.d6335352.Travel-Guide-Hotels) - [Sidirochori Hotels](https://www.expedia.co.uk/Sidirochori-Hotels.d6335338.Travel-Guide-Hotels) - [Smíxi Hotels](https://www.expedia.co.uk/Smixi-Hotels.d3000030215.Travel-Guide-Hotels) - [Tsotilion Hotels](https://www.expedia.co.uk/Tsotilion-Hotels.d6335353.Travel-Guide-Hotels) - [Tsotyli Hotels](https://www.expedia.co.uk/Tsotyli-Hotels.d3000475751.Travel-Guide-Hotels) - [Varikon Hotels](https://www.expedia.co.uk/Varikon-Hotels.d6335271.Travel-Guide-Hotels) - [Vevi Hotels](https://www.expedia.co.uk/Vevi-Hotels.d6335283.Travel-Guide-Hotels) - [Vitsi Hotels](https://www.expedia.co.uk/Vitsi-Hotels.d6334824.Travel-Guide-Hotels) - [Vlasti Hotels](https://www.expedia.co.uk/Vlasti-Hotels.d6335281.Travel-Guide-Hotels) - [Voio Hotels](https://www.expedia.co.uk/Voio-Hotels.d6334814.Travel-Guide-Hotels) - [Zakas Hotels](https://www.expedia.co.uk/Zakas-Hotels.d6335295.Travel-Guide-Hotels) ### Flights - [Flights to Florina](https://www.expedia.co.uk/Cheap-Flights-To-Florina.d6024959.Travel-Guide-Flights) - [Flights to Kastoria](https://www.expedia.co.uk/Cheap-Flights-To-Kastoria.d1928.Travel-Guide-Flights) - [Flights to Mouriki](https://www.expedia.co.uk/Cheap-Flights-To-Mouriki.d553248635976431739.Travel-Guide-Flights) - [Flights to Nymfaio](https://www.expedia.co.uk/Cheap-Flights-To-Nymfaio.d6335267.Travel-Guide-Flights) - [Flights from Aristoteles](https://www.expedia.co.uk/lp/airports/kso/flights-from-aristoteles-airport) - [Flights from Amyntaio](https://www.expedia.co.uk/lp/flights/6334813/flights-from-amyntaio) - [Flights from Athens (ATH) to Kastoria (KSO)](https://www.expedia.co.uk/lp/flights/ath/kso/athens-to-kastoria) - [Flights from Birmingham (BHX) to Kastoria (KSO)](https://www.expedia.co.uk/lp/flights/bhx/kso/birmingham-to-kastoria) - [Flights from London (LHR) to Kastoria (KSO)](https://www.expedia.co.uk/lp/flights/lhr/kso/london-to-kastoria) ### Packages - [Agios Kosmas Holidays](https://www.expedia.co.uk/Agios-Kosmas.d3000476526.Holidays-City-Breaks) - [Visit Agios Kosmas](https://www.expedia.co.uk/Agios-Kosmas.dx3000476526) - [Visit Aminteo](https://www.expedia.co.uk/Aminteo.dx3000476507) - [Byzantine Museum of Kastoria](https://www.expedia.co.uk/Byzantine-Museum-Of-Kastoria-Kastoria.d6263517.Attraction) - [Eordaia Holidays](https://www.expedia.co.uk/Eordaia.d6334970.Holidays-City-Breaks) - [Visit Eordaia](https://www.expedia.co.uk/Eordaia.dx6334970) - [Visit Florina](https://www.expedia.co.uk/Florina.dx6024959) - [Holy Prophet Elias Church](https://www.expedia.co.uk/Holy-Prophet-Elias-Church-Kastoria.d553248635935219972.Attraction) - [Visit Kaloneri](https://www.expedia.co.uk/Kaloneri.dx3000389214) - [Kastoria Holidays](https://www.expedia.co.uk/Kastoria.d1928.Holidays-City-Breaks) - [Visit Kastoria](https://www.expedia.co.uk/Kastoria.dx1928) - [Visit Lavda](https://www.expedia.co.uk/Lavda.dx3000463532) - [Nestorio Holidays](https://www.expedia.co.uk/Nestorio.d6345335.Holidays-City-Breaks) - [Visit Nestorio](https://www.expedia.co.uk/Nestorio.dx6345335) - [Nymfaio Holidays](https://www.expedia.co.uk/Nymfaio.d6335267.Holidays-City-Breaks) - [Polinerion Holidays](https://www.expedia.co.uk/Polinerion.d6335294.Holidays-City-Breaks) - [Ptolemaida Holidays](https://www.expedia.co.uk/Ptolemaida.d6335276.Holidays-City-Breaks) - [Visit Ptolemaida](https://www.expedia.co.uk/Ptolemaida.dx6335276) - [Visit Samarina](https://www.expedia.co.uk/Samarina.dx6240088) - [Visit Siatista](https://www.expedia.co.uk/Siatista.dx6335352) - [Vitsi Holidays](https://www.expedia.co.uk/Vitsi.d6334824.Holidays-City-Breaks) - [Vlasti Holidays](https://www.expedia.co.uk/Vlasti.d6335281.Holidays-City-Breaks) - [Voio Holidays](https://www.expedia.co.uk/Voio.d6334814.Holidays-City-Breaks) - [Visit Voio](https://www.expedia.co.uk/Voio.dx6334814) ### Cars - [Car hire Aetos](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Aetos.d6335261.Car-Hire-Guide) - [Car hire Florina](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Florina.d6024959.Car-Hire-Guide) - [Car hire Kastoria](https://www.expedia.co.uk/Compare-Cheap-Car-Hire-In-Kastoria.d1928.Car-Hire-Guide) ### Holiday Homes - [Vevi Holiday Rentals](https://www.expedia.co.uk/Vevi-Holiday-Rentals.d6335283.Travel-Guide-HolidayRentals) \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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