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Our top choices for Mayo Clinic Florida hotels

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area
3.0 star property
0.7 mi from Mayo Clinic Florida
9.4 out of 10, Exceptional, (475 reviews)
"Great stay! Clean room, friendly staff. "
United States
Sabrena
The price is £138
includes taxes & fees
3 Apr - 4 Apr
Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Hilton Jacksonville At Mayo Clinic

Hilton Jacksonville At Mayo Clinic
4.5 star property
0.5 mi from Mayo Clinic Florida
9.4 out of 10, Exceptional, (183 reviews)
"Great place to stay"
United States
Judy
The price is £149
includes taxes & fees
3 Apr - 4 Apr
Hilton Jacksonville At Mayo Clinic

TownePlace Suites by Marriott Jacksonville East

TownePlace Suites by Marriott Jacksonville East
3.0 star property
Golden Glades - The Woods, 1.9 mi from Mayo Clinic Florida
9.2 out of 10, Wonderful, (593 reviews)
"Very nice accommodation , clean , and comfortable"
United States
Kevin
The price is £101
includes taxes & fees
25 Apr - 26 Apr
TownePlace Suites by Marriott Jacksonville East

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
2.5 star property
Golden Glades - The Woods, 1.9 mi from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,000 reviews)
"Nice room nice stay friendly staff"
United States
Thomas
The price is £93
includes taxes & fees
19 Apr - 20 Apr
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
2.5 star property
1.6 mi from Mayo Clinic Florida
8.8 out of 10, Excellent, (1,008 reviews)
"Great stay!"
United States
Satavia
The price is £87
includes taxes & fees
26 Apr - 27 Apr
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
3.0 star property
0.2 mi from Mayo Clinic Florida
8.4 out of 10, Very good, (767 reviews)
"Room very clear; staff friendly and helpful; safe parking with accessibility to Mayo Clinic "
United States
Nancy
The price is £136
includes taxes & fees
18 Apr - 19 Apr
Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

The Hotel Palms Poolside

The Hotel Palms Poolside
2.5 star property
4.8 mi from Mayo Clinic Florida
9.8 out of 10, Exceptional, (456 reviews)
"The room was clean, staff was friendly and helpful, and location was great. "
United States
Rocky
The price is £161
includes taxes & fees
8 Apr - 9 Apr
The Hotel Palms Poolside

Element Jacksonville Beach

Element Jacksonville Beach
3.0 star property
3.4 mi from Mayo Clinic Florida
9.6 out of 10, Exceptional, (543 reviews)
"Rooms were clean. Proximity to beach was optimal. Daily made to order breakfast was simply amazing. "
United States
Sean M
The price is £161
includes taxes & fees
19 Apr - 20 Apr
Element Jacksonville Beach

Holiday Inn Express Jacksonville Beach by IHG

Holiday Inn Express Jacksonville Beach by IHG
3.0 star property
2.9 mi from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1,003 reviews)
"Great hotel, very friendly, free breakfast! "
United States
Daniel
The price is £106
includes taxes & fees
26 Apr - 27 Apr
Holiday Inn Express Jacksonville Beach by IHG

The Hotel Palms Courtyard

The Hotel Palms Courtyard
3.5 star property
4.8 mi from Mayo Clinic Florida
9.6 out of 10, Exceptional, (294 reviews)
"stayed here for an event and it was awesome"
United States
clayton
The price is £151
includes taxes & fees
29 Mar - 30 Mar
The Hotel Palms Courtyard

Ponte Vedra Inn & Club

Ponte Vedra Inn & Club
5.0 star property
3.9 mi from Mayo Clinic Florida
9.4 out of 10, Exceptional, (818 reviews)
"Wonderful place to visit to relax. Very clean, very friendly and courteous staff. Great view from the balcony."
United States
Greg
The price is £519
includes taxes & fees
16 Apr - 17 Apr
Ponte Vedra Inn & Club

The Lodge and Club at Ponte Vedra Beach

The Lodge and Club at Ponte Vedra Beach
5.0 star property
3.9 mi from Mayo Clinic Florida
9.4 out of 10, Exceptional, (690 reviews)
"Incredible visit as my family does not stay at places like this. The service was great so we will be looking for more places like this in the future."
United States
Rachel
The price is £436
includes taxes & fees
12 Apr - 13 Apr
The Lodge and Club at Ponte Vedra Beach

AC Hotel Jacksonville St Johns Town Center

AC Hotel Jacksonville St Johns Town Center
2.5 star property
Southside, 5 mi from Mayo Clinic Florida
9.4 out of 10, Exceptional, (184 reviews)
"Staff was excellent...highly recommend this Hotel"
Canada
Robert
The price is £151
includes taxes & fees
29 Mar - 30 Mar
AC Hotel Jacksonville St Johns Town Center

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
2.5 star property
2.6 mi from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,057 reviews)
"Great staff and Clean hotel "
United States
Tyniesha
The price is £110
includes taxes & fees
19 Apr - 20 Apr
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach
2.5 star property
3.7 mi from Mayo Clinic Florida
9.0 out of 10, Wonderful, (3,785 reviews)
"beautiful hotel, good location"
United States
Robert E.
The price is £144
includes taxes & fees
22 Apr - 23 Apr
Margaritaville Jacksonville Beach

Best Western Oceanfront

Best Western Oceanfront
3.0 star property
3.6 mi from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,002 reviews)
"Good location, helpful staff, comfortable room with a great Oceanview balcony."
United States
Robert
The price is £127
includes taxes & fees
19 Apr - 20 Apr
Best Western Oceanfront

Tru By Hilton Jacksonville St Johns Town Center

Tru By Hilton Jacksonville St Johns Town Center
2.5 star property
Southside, 5.4 mi from Mayo Clinic Florida
9.2 out of 10, Wonderful, (875 reviews)
"Clean room, professional staff, & good breakfast bar"
United States
Dwight
The price is £104
includes taxes & fees
5 Apr - 6 Apr
Tru By Hilton Jacksonville St Johns Town Center

Springhill Suites By Marriott Jacksonville Beach Oceanfront

Springhill Suites By Marriott Jacksonville Beach Oceanfront
4.0 star property
3.6 mi from Mayo Clinic Florida
9.0 out of 10, Wonderful, (655 reviews)
"Good clean rooms and property "
United States
Michael
The price is £162
includes taxes & fees
19 Apr - 20 Apr
Springhill Suites By Marriott Jacksonville Beach Oceanfront

Hyatt Place Jacksonville / St. Johns Town Center

Hyatt Place Jacksonville / St. Johns Town Center
3.0 star property
Southside, 5.4 mi from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1,000 reviews)
"Great place to stay at!"
United States
R.
The price is £114
includes taxes & fees
5 Apr - 6 Apr
Hyatt Place Jacksonville / St. Johns Town Center

Four Points by Sheraton Jacksonville Beachfront

Four Points by Sheraton Jacksonville Beachfront
3.0 star property
3.5 mi from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,002 reviews)
"Good room"
United States
Michael
The price is £194
includes taxes & fees
12 Apr - 13 Apr
Four Points by Sheraton Jacksonville Beachfront
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels close to Mayo Clinic Florida

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Lobby lounge
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
3.0 star property
9.4
Exceptional
475 reviews
View
Breakfast, lunch, dinner served; American cuisine
Hilton Jacksonville At Mayo Clinic
4.5 star property
9.4
Exceptional
183 reviews
View
Terrace/patio
TownePlace Suites by Marriott Jacksonville East
3.0 star property
9.2
Wonderful
593 reviews
View
Lobby
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
2.5 star property
9.0
Wonderful
1,000 reviews
View
Lobby sitting area
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
2.5 star property
8.8
Excellent
1,008 reviews
View

Top Mayo Clinic Florida Hotel Reviews

Hotels near other Mayo Clinic Florida attractions

Frequently asked questions

What's the area like around Mayo Clinic Florida?
Mayo Clinic Florida is located in a welcoming area of Jacksonville known for its beautiful beaches and surfing. If you're looking for a convenient place to stay, take a look at the 49 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay close to Mayo Clinic Florida?
Adjacent to Mayo Clinic Florida, Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and an outdoor pool. Other good choices close by include Hilton Jacksonville At Mayo Clinic and Residence Inn By Marriott Jacksonville - Mayo Clinic Area.
How many hotels are there near Mayo Clinic Florida?
Expedia has 49 hotels and other accommodation options within a mile from Mayo Clinic Florida.
If I need to cancel the hotel reservation for my stay near Mayo Clinic Florida, will I receive a refund?
Yes! You'll find that most hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to view the top deals on offer near Mayo Clinic Florida.
What can I see and do near Mayo Clinic Florida?
You can catch a show at SeaWalk Pavillion, Players by the Sea and SeaWalk Pavillion. Spend some time exploring the the natural beauty of Huguenot Park, Oceanfront Park and Cradle Creek Preserve. Lounge by the water at Northeast Florida Beaches and Ponte Vedra Beach.