Main Street Hyannis

Main Street Hyannis
Main Street Hyannis
Main Street Hyannis
Main Street Hyannis
Main Street Hyannis

Plan a trip to see Main Street Hyannis

Price found within the past 48 hours. Click for updated prices.
Comfort Inn Hyannis - Cape Cod

Comfort Inn Hyannis - Cape Cod

2.5 out of 5
per person
9 Oct - 16 Oct
found 18 hours ago
Return direct flight included
Manchester (MAN) to Hyannis (HYA)
7.8/10 Good! (1,000 reviews)
We really found this hotel to be very nice! The bed, sheets, pillows were very comfortable. The breakfast (i had read)was disappointing, however we found it to have been well stocked and although the breakfast area got congested, it was quite sufficient. Pool indoor and outdoor. Surprisingly very quiet although it was full. Felt safe. We were very pleased. I would stay there again.

Reviewed on 1 Aug 2025

Heritage House Inn on Cape Cod

Heritage House Inn on Cape Cod

2.5 out of 5
per person
13 Oct - 20 Oct
found 1 day ago
Return flight included
London (LON) to Hyannis (HYA)
7.4/10 Good! (125 reviews)
First, let me say you get what you paid for. Absolutely would never stay at this place again. It took 18 minutes just to check in. Mildew, damp smell right when you walk in the building. Would never use the ice machine. Finally found our room... had an extremely hard time to get in! Every time having to actually kick the door just to get in. Very musty and damp...sheets were damp...all our clothes were mildew smell and damp. No closet with hangers for clothes. No hooks in bathroom for anything. Not great lighting in room at all. We have pictures to prove if needed.

Reviewed on 2 Aug 2025

Margaritaville Resort Cape Cod

Margaritaville Resort Cape Cod

4 out of 5
per person
7 Sept - 13 Sept
found 1 hour ago
Return direct flight included
London (LHR) to Hyannis (HYA)
8.8/10 Excellent! (238 reviews)
Now that the resort has been renovated, it is divine for families!

Reviewed on 5 Aug 2025

Popular places to visit

John F. Kennedy Hyannis Museum showing a statue or sculpture

John F. Kennedy Hyannis Museum

Learn about the 35th president of the United States at this revealing museum, which is just a short distance from the Kennedy Compound.

John F. Kennedy Hyannis Museum
Hyannis

Cape Cod Maritime Museum

You can spend an afternoon studying the exhibits at Cape Cod Maritime Museum during your trip to Hyannis. Stroll along the waterfront in this family-friendly area or visit its seafood restaurants.

Cape Cod Maritime Museum
St. Francis Xavier Church

St. Francis Xavier Church

Learn about the local history of Hyannis with a stop at St. Francis Xavier Church. Amble around this family-friendly area's beautiful beaches and enjoy its seafood restaurants.

St. Francis Xavier Church
Hyannis Harbor featuring a bay or harbour and a sunset as well as a small group of people

Hyannis Harbor

See the Cape Cod peninsula from a different perspective by riding a boat out of this picturesque harbor or wandering along its docks and jetties.

Hyannis Harbor
John F. Kennedy Memorial

John F. Kennedy Memorial

Take a moment to reflect on John F. Kennedy’s defining role in American politics, as well as his untimely death, at this poignant memorial.

John F. Kennedy Memorial

Hyannis Armory

Learn about the local history of Hyannis with a stop at Hyannis Armory. Wander the waterfront and beautiful beaches in the area.

Hyannis Armory

Top Hotel Deals

Hyannis Plaza Hotel

Hyannis Plaza Hotel

2.5 out of 5
662 Main Street, Hyannis, MA
Hyannis Plaza Hotel
Comfort Inn Hyannis - Cape Cod

Comfort Inn Hyannis - Cape Cod

2.5 out of 5
259 Main Street, Hyannis, MA
Comfort Inn Hyannis - Cape Cod
Heritage House Inn on Cape Cod

Heritage House Inn on Cape Cod

2.5 out of 5
540 Old Colony Rd, Hyannis, MA
Heritage House Inn on Cape Cod
Hyannis Inn

Hyannis Inn

2 out of 5
473 MAIN ST, Hyannis, MA
Hyannis Inn
Hyannis Harbor Hotel

Hyannis Harbor Hotel

3.5 out of 5
213 Ocean St, Hyannis, MA
Hyannis Harbor Hotel
Cape Cod Inn

Cape Cod Inn

2 out of 5
447 Main St, Hyannis, MA
Cape Cod Inn
Americas Best Value Inn & Suites Hyannis Cape Cod

Americas Best Value Inn & Suites Hyannis Cape Cod

2 out of 5
206 Main St, Hyannis, MA
Americas Best Value Inn & Suites Hyannis Cape Cod
Anchor In Distinctive Waterfront Lodging

Anchor In Distinctive Waterfront Lodging

3 out of 5
1 South Street, Hyannis, MA
Anchor In Distinctive Waterfront Lodging
SeaCoast Inn

SeaCoast Inn

2 out of 5
33 Ocean Street, Hyannis, MA
SeaCoast Inn
See all 3,695 properties in Main Street Hyannis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.