Title: TOP Luxury Hotels in Little Italy, San Diego for 2025 - Little Italy Upscale Hotels | Expedia.co.uk [Little Italy Travel Guide](https://expedia.co.uk/San-Diego-Little-Italy.dx6161280)[Holiday Rentals in San Diego](https://expedia.co.uk/San-Diego-Holiday-Rentals.d3073.Travel-Guide-HolidayRentals)[Flights to San Diego](https://expedia.co.uk/Cheap-Flights-To-San-Diego.d3073.Travel-Guide-Flights)[Things to do in San Diego](https://expedia.co.uk/Things-To-Do-In-San-Diego.d3073.Travel-Guide-Activities)[Little Italy Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Little-Italy.d6161280.Car-Hire-Guide)[Little Italy Holidays](https://expedia.co.uk/Little-Italy.d6161280.Holidays-City-Breaks) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/481000/481026-Little-Italy-San-Diego.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Luxury Hotels in Little Italy, San Diego ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Little Italy Luxury Hotels Tonight [12 Oct - 13 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6161280&startDate=2025-10-12&endDate=2025-10-13&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [13 Oct - 14 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6161280&startDate=2025-10-13&endDate=2025-10-14&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [17 Oct - 19 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6161280&startDate=2025-10-17&endDate=2025-10-19&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [24 Oct - 26 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6161280&startDate=2025-10-24&endDate=2025-10-26&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Little Italy Luxury Hotels ![Front of property](https://images.trvl-media.com/lodging/1000000/900000/893700/893673/89625d2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds | In-room safe, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/900000/893700/893673/3681c904.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/900000/893700/893673/a09a751d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 Queen Bed | In-room dining](https://images.trvl-media.com/lodging/1000000/900000/893700/893673/ec05fe8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Harborview Inn & Suites San Diego Harbor Downtown San Diego 7.2/10 Good (1009) "Home away from home when we travel.free parking pleasant staff " £78 includes taxes & fees 13 Oct - 14 Oct [](https://www.expedia.co.uk/San-Diego-Hotels-Harborview-Inn-Suites-San-Diego-Harbor.h893673.Hotel-Information) ![Check-in/check-out kiosk](https://images.trvl-media.com/lodging/8000000/7350000/7341300/7341280/d0638ef7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/8000000/7350000/7341300/7341280/3fc9f7d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/8000000/7350000/7341300/7341280/ff1db9c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/8000000/7350000/7341300/7341280/b8a10ffe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Urban Boutique Hotel Downtown San Diego 8.6/10 Excellent (1259) "Great location, clean rooms, really nice continental breakfast and very nice staff😊" £80 includes taxes & fees 22 Oct - 23 Oct [](https://www.expedia.co.uk/San-Diego-Hotels-Urban-Boutique-Hotel.h7341280.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/14000000/13150000/13147100/13147064/51cda467.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/14000000/13150000/13147100/13147064/7b8bd3d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/14000000/13150000/13147100/13147064/ea596309.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout curtains, free WiFi, bed sheets](https://images.trvl-media.com/lodging/14000000/13150000/13147100/13147064/c54ec7e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 San Diego Airport - Harbor Downtown San Diego 7.0/10 Good (1008) "Super close to San Diego attractions " £66 includes taxes & fees 13 Oct - 14 Oct [](https://www.expedia.co.uk/San-Diego-Hotels-Motel-6-San-Diego-Airport-Harbor.h13147064.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/920000/914400/914373/236157bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast area](https://images.trvl-media.com/lodging/1000000/920000/914400/914373/e45ffdb8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/920000/914400/914373/w395h595x4y3-183171c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/920000/914400/914373/dc860349.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Pensione Hotel Downtown San Diego 8.6/10 Excellent (1882) "Very happy with our stay " £112 includes taxes & fees 20 Oct - 21 Oct [](https://www.expedia.co.uk/San-Diego-Hotels-La-Pensione-Hotel.h914373.Hotel-Information) ![Rooftop terrace](https://images.trvl-media.com/lodging/1000000/50000/41700/41635/e44ce490.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/50000/41700/41635/942a830e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop pool](https://images.trvl-media.com/lodging/1000000/50000/41700/41635/feebe7fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Food and drink](https://images.trvl-media.com/lodging/1000000/50000/41700/41635/a2fbcf30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Porto Vista Hotel Downtown Downtown San Diego 6.6/10 (1185) "Great place to stay, with awesome staff (very helpful friendly and knowledgable" [](https://www.expedia.co.uk/San-Diego-Hotels-Porto-Vista-Hotel.h41635.Hotel-Information) ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/1000000/560000/551900/551889/fc9f5c5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/560000/551900/551889/896515f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom, Non Smoking | Living area | 32-inch LCD TV with premium TV channels, TV](https://images.trvl-media.com/lodging/1000000/560000/551900/551889/14ea58da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/560000/551900/551889/d450dfd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn San Diego-Downtown Downtown San Diego 8.2/10 Very good (2171) "Beautiful place " £120 includes taxes & fees 26 Oct - 27 Oct [](https://www.expedia.co.uk/San-Diego-Hotels-Hampton-Inn-San-Diego-Downtown.h551889.Hotel-Information) ![View from room](https://images.trvl-media.com/lodging/1000000/20000/13300/13205/0339a25b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Suite, 1 Bedroom, Non Smoking | Living room | 55-inch TV with cable channels](https://images.trvl-media.com/lodging/1000000/20000/13300/13205/7182df27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, in-room safe, desk, blackout curtains](https://images.trvl-media.com/lodging/1000000/20000/13300/13205/a7d908f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/20000/13300/13205/fa05a7b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott San Diego Downtown Little Italy Downtown San Diego 8.2/10 Very good (1089) "was a great stay!" £110 includes taxes & fees 20 Oct - 21 Oct [](https://www.expedia.co.uk/San-Diego-Hotels-The-Little-Italy-Hotel-In-Downtown-San-Diego.h13205.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/1000000/870000/869400/869302/cb2cd0e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/870000/869400/869302/e88847f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds | Pillow-top beds, in-room safe, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/870000/869400/869302/0f74be03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/870000/869400/869302/487a96d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Pacific Downtown San Diego 6.0/10 (396) "It was the best hotel we stayed at for our stay in SanDiego. The pool was awesome and it was by the harbor. I would recommend it to everyone. If I ever go back to SanDiego I would stay there" [](https://www.expedia.co.uk/San-Diego-Hotels-The-Pacific.h869302.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-26&endDate=2025-10-27®ionId=6161280&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true) ## Find out more about Little Italy ### Little Italyand its attractions for luxury travelers Little Italy in San Diego is a vibrant neighbourhood that beautifully marries rich Italian heritage with modern luxury. Begin your journey at the iconic Piazza della Famiglia, where you can enjoy al fresco dining amidst stunning architecture, and don't miss the chance to sample authentic Italian gelato from one of the local parlours. For those with an adventurous spirit, a visit to the acclaimed Little Italy Food Hall offers a culinary exploration of artisanal bites, perfect for savvy foodies seeking gourmet experiences. You can also indulge in a private wine tasting at the nearby Vino Carta, where exquisite wines await, paired with expert recommendations. Finally, immerse yourself in the local arts scene at the Little Italy Art Walk, which showcases an array of talented artists and their works. When it comes to accommodation, luxury hotels in Little Italy provide a sophisticated base for your adventures, featuring rooftop lounges with panoramic views, spa services that pamper the senses, and attentive concierge teams dedicated to curating unforgettable experiences just for you. With the charm of the neighbourhood and the comfort of upscale lodging, your stay in Little Italy promises to be both relaxing and exhilarating. ## Top Little Italy Hotel Reviews ![Hard Rock Hotel San Diego](//images.trvl-media.com/lodging/2000000/1740000/1731600/1731557/fbbdfc57_y.jpg) ### Hard Rock Hotel San Diego 10/10 Excellent "Very responsive when requesting additional towels and toiletries. " [](https://expedia.co.uk/San-Diego-Hotels-Hard-Rock-Hotel-San-Diego.h1731557.Hotel-Information) ![La Pensione Hotel](//images.trvl-media.com/lodging/1000000/920000/914400/914373/236157bf_y.jpg) ### La Pensione Hotel 10/10 Excellent "We've stayed here before and will again. The rooms are small but has everything we need to enjo San Diego. " [](https://expedia.co.uk/San-Diego-Hotels-La-Pensione-Hotel.h914373.Hotel-Information) ![Urban Boutique Hotel](//images.trvl-media.com/lodging/8000000/7350000/7341300/7341280/d0638ef7_y.jpg) ### Urban Boutique Hotel 10/10 Excellent "Super friendly staff. Great location. " [](https://expedia.co.uk/San-Diego-Hotels-Urban-Boutique-Hotel.h7341280.Hotel-Information) ![Hampton Inn San Diego-Downtown](//images.trvl-media.com/lodging/1000000/560000/551900/551889/fc9f5c5b_y.jpg) ### Hampton Inn San Diego-Downtown 10/10 Excellent "Peefect " [](https://expedia.co.uk/San-Diego-Hotels-Hampton-Inn-San-Diego-Downtown.h551889.Hotel-Information) ![Manchester Grand Hyatt San Diego](//images.trvl-media.com/lodging/1000000/20000/12100/12073/w3840h2092x0y3-447c77a4_y.jpg) ### Manchester Grand Hyatt San Diego 10/10 Excellent "Excellent rooms, very clean and modern. Well trained staff and good food. This is one of the best hotels near a convention center. Highly recommend it. " [](https://expedia.co.uk/San-Diego-Hotels-Manchester-Grand-Hyatt-San-Diego.h12073.Hotel-Information) ![DoubleTree by Hilton San Diego - Del Mar](//images.trvl-media.com/lodging/1000000/20000/15300/15236/5afe6cec_y.jpg) ### DoubleTree by Hilton San Diego - Del Mar 10/10 Excellent "Nice staff.! " [](https://expedia.co.uk/San-Diego-Hotels-DoubleTree-By-Hilton-San-Diego-Del-Mar.h15236.Hotel-Information) ![Porto Vista Hotel Downtown](//images.trvl-media.com/lodging/1000000/50000/41700/41635/e44ce490_y.jpg) ### Porto Vista Hotel Downtown 10/10 Excellent "Very warm and Cozy room " [](https://expedia.co.uk/San-Diego-Hotels-Porto-Vista-Hotel.h41635.Hotel-Information) ![Wyndham San Diego Bayside](//images.trvl-media.com/lodging/1000000/20000/11200/11177/c44ff51d_y.jpg) ### Wyndham San Diego Bayside 10/10 Excellent "Loved the location & ease of access to the city." [](https://expedia.co.uk/San-Diego-Hotels-Wyndham-San-Diego-Bayside.h11177.Hotel-Information) ![Best Western Plus Marina Gateway Hotel](//images.trvl-media.com/lodging/3000000/2820000/2816700/2816688/f3777dfe_y.jpg) ### Best Western Plus Marina Gateway Hotel 10/10 Excellent "The soap dispenser in the shower was detached from the wall and the AC was blowing a weird smell...like wet clothes." [](https://expedia.co.uk/National-City-Hotels-Best-Western-Plus-Marina-Gateway-Hotel.h2816688.Hotel-Information) ## Frequently asked questions ### Are you looking for a luxury hotel for your stay in Little Italy? > Expedia can help you get a flight to San Diego, CA (SAN-San Diego Intl.) airport or San Diego, CA (MYF-Montgomery Field) airport, and then you can select from a variety of places to stay that will deliver the luxury you seek. Amenities are important when you plan a holiday, so we make it easy to find what you'd like to make your stay relaxing and comfortable. If you want an upscale hotel that has a spa, an indoor pool or luxury bedding, Expedia can assist you in finding the best luxury hotel experience that Little Italy offers. During your visit, you might want to enjoy the restaurants and cafes which Little Italy is known for. ### What's there to see and do in Little Italy? > Experience Little Italy with a stop at Maritime Museum of San Diego, San Diego Bay and Star of India. If you have a bit of extra time while you're in the area, you might want to check out San Diego Zoo and Mission Bay. ### How can I get around Little Italy? > It's easier to get around town comfortably when you know your options. 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