Photo by Michael Schuier

Search Holiday Homes in Ladys Island

    price find illustration
    Change your mind
    Book hotels with free cancellation
    deals illustration
    Treat yourself
    Save instantly and earn perks with One Key
    bed illustration
    Be picky
    Search almost a million properties worldwide

Check prices for these dates

Next weekend
In two weeks
In one month
In two months

Browse Select Ladys Island Holiday Homes

Cute home, great for MCRD families (entire home)

8.6 out of 10, Excellent, (29)
"Very cute little home! The kitchen needs a few more staples, ie pots and pans. But i live to cook so i could be biased. Wonderful neighborhood! Loved our stay!!"
Cute home, great for MCRD families (entire home)

NEW LISTING ~ 3 Bedroom ~ Pet Friendly ~ Coastal Casual & Refined Style ~ 8 Cotton Lane

10.0 out of 10, Exceptional, (17)
"Clean & accommodating; such a relaxing stay for our family of 4 plus our pup. Wonderful stay!"
NEW LISTING ~ 3 Bedroom ~ Pet Friendly ~ Coastal Casual & Refined Style ~ 8 Cotton Lane

Charming Pet-Friendly Beach Home

8.0 out of 10, Very good, (1)
"Newly renovated and good location however the air conditioning didn’t work for 2 days until the host finally responded and sent someone out to look at it. Other than that it was clean, comfortable and had everything you need for your stay. "
Charming Pet-Friendly Beach Home

Charming house with a large fenced lot in a central location

9.8 out of 10, Exceptional, (29)
"Nice and clean, great location. "
Charming house with a large fenced lot in a central location

New rental overlooking Plantation Course 9th tee box. 1500 sq feet, smoke free.

9.6 out of 10, Exceptional, (16)
"Nice condo, comfortable stay."
New rental overlooking Plantation Course 9th tee box. 1500 sq feet, smoke free.

Marriott's Harbour Club

3.5 star property
9.0 out of 10, Wonderful, (58)
"Villa provided a perfect accommodation for adult children with parents- full kitchen was stocked with everything you need. Most kitchen items looked brand new! So close to Harbour Town shops and restaurants! It’s very quiet and the property is laid out to make even the balcony private! "
The price is £400
includes taxes & fees
7 Jul - 8 Jul
Marriott's Harbour Club

Edisto Beach Getaway!- Beach Walk!

10.0 out of 10, Exceptional, (3)
"This property is ideally situated, close to the beach but so quiet for rest and sleep! And we were equidistant to the point and state beach! Spacious, great outdoor shower, big TV, comfortable beds!"
Edisto Beach Getaway!- Beach Walk!

Recently Built House! Pets Stay Free! Close to Amenities

10.0 out of 10, Exceptional, (66)
"This home was wonderful for our family to enjoy while our son graduated from Marines."
Recently Built House! Pets Stay Free! Close to Amenities

5 Mi to Beach: Spacious Home on Hilton Head Island

5 Mi to Beach: Spacious Home on Hilton Head Island

On Lagoon & Golf course! Tons of Wildlife & Amazing views of Fairways 1, 2, 8, 9

On Lagoon & Golf course! Tons of Wildlife & Amazing views of Fairways 1, 2, 8, 9

Golf Cart, River and Marsh Views, Oceanfront Community, Beautiful Sunsets

9.8 out of 10, Exceptional, (170)
"We enjoyed our stay in the low country!! Oyster festival was fun and delicious. Accommodations were great and plenty of space for our family!!"
Golf Cart, River and Marsh Views, Oceanfront Community, Beautiful Sunsets

Beautiful Dog-friendly condo with full kitchen, free wifi and golf course views

8.0 out of 10, Very good, (40)
"The unit was very nice! Beautiful view of the golf course! Would definitely stay here again."
Beautiful Dog-friendly condo with full kitchen, free wifi and golf course views

Relax at Sandpiper Cottage: Fripp Island Gem with Bikes, Smart TVs, Deck, and Pet-Friendly Comfort!

9.8 out of 10, Exceptional, (10)
"Hi, This was an excellent place for my husband and me to stay when we visited family on Fripp Island. It was a cheerful, clean cottage with all the amenities. The host was beneficial and checked in with us throughout the visit. We would stay here again."
Relax at Sandpiper Cottage: Fripp Island Gem with Bikes, Smart TVs, Deck, and Pet-Friendly Comfort!

Ideal Location in Downtown Bluffton ~Just Steps to the May River

10.0 out of 10, Exceptional, (21)
"Everything about our vacation was good! Very clean, terrific communication, nice location. Will definitely do it again."
Ideal Location in Downtown Bluffton ~Just Steps to the May River

Stunning Sea Pines Treetop Oasis Deck & Grill with short walk to Harbourtown

10.0 out of 10, Exceptional, (54)
"Excellent location and great place to stay. Very cozy and short distance to harbour town."
The price is £306
includes taxes & fees
6 Jul - 7 Jul
Stunning Sea Pines Treetop Oasis Deck & Grill with short walk to Harbourtown

Direct Oceanfront Luxury Home, Large Private Pool and Spa, Elevator, Concierge!

10.0 out of 10, Exceptional, (154)
"Great property and location. "
Direct Oceanfront Luxury Home, Large Private Pool and Spa, Elevator, Concierge!

Castle by the Sea 7BR/8BA Luxury Home with Elevator

10.0 out of 10, Exceptional, (136)
"Absolutely loved the layout of the home, the kid friendly “extras”, the pool & hot tub set up…I could go on and on! The location is perfectly located on a quiet part of the island but within walking distance to restaurants, shops, ice cream, bars, and walking/biking paths. This was the perfect home for our family to gather for spring break. "
Castle by the Sea 7BR/8BA Luxury Home with Elevator

Forest Beach Townhome - 2BR/1.5 Bath - Pet Friendly - Short Walk to Beach

9.0 out of 10, Wonderful, (17)
"Great area! Close to everything including beach, food, park. "
Forest Beach Townhome - 2BR/1.5 Bath - Pet Friendly - Short Walk to Beach

1 minute to the Beach-New flooring-updated decor and pool area-FREE Pool Heat!

9.0 out of 10, Wonderful, (71)
"Location was great and house was well-equipped. Host was responsive before and during our stay. Would stay again."
1 minute to the Beach-New flooring-updated decor and pool area-FREE Pool Heat!

12 Flamingo: 5th row Beach Cottage has a private pool pet friendly.

7.8 out of 10, Good, (11)
"Wonderful house"
12 Flamingo: 5th row Beach Cottage has a private pool pet friendly.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in