La Mesa Holidays from £502
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to £750 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPackages with flights are ATOL protected
Top La Mesa Flight + Hotel Deals
Price found within the past 48 hours. Click for updated prices.
Riande Aeropuerto Hotel & Casino
Tocumen Airport
£515
per person
13 Nov - 17 Nov
found 12 hours ago
Return flight included
Kingston (KIN) to Panama City (PTY)
8.6/10 Excellent! (1,819 reviews)
Nice place for a 1 night stay. Nothing fancy. Rooms and hotel a little outdated but the breakfast was good. So a nice place for a 1 night stay during a layover.
Reviewed on 10 Oct 2026
La Mesa Essential Information
Language | Spanish |
|---|---|
Currency | Panamanian balboas |
Local Welcome | ¡Hola! |
Local Goodbye | Adiós |
Closest Airport | Tocumen Intl. Airport (PTY) |
Population | 1,450 |
Max Temp Winter | 29ºC |
Max Temp Summer | 29ºC |
Top hotels in La Mesa
Crowne Plaza Panama Airport by IHG
Ave. Domingo Diaz Tocumen Panama
Fully refundable
£121
9 Nov - 10 Nov
includes taxes & fees
Ramada Plaza by Wyndham Panama Punta Pacifica
Via Israel y Calle 71, San Francisco Panama City Panama
£81
10 Nov - 11 Nov
includes taxes & fees
Aloft by Marriott Panama
Via Israel & Calle 76 Panama City Panama
Fully refundableReserve now, pay when you stay
£104
16 Oct - 17 Oct
includes taxes & fees
8.8/10 Excellent! (1,001 reviews)
"The room telephone was not operational. I asked the front desk for assistance twice, and it was never resolved. I was trying to order room service. So I had to walk downstairs each time I wanted service instead of having it delivered to my room. I wasn't happy about that."
Reviewed on 10 Oct 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
What to do in La Mesa
Private tour of Panama City and visit to the Miraflores Locks
£50
per adult
100% of travellers recommend
Eco Agro Adventure with Horseback Riding in a Private Ranch
£56
per adult
Panama Layover tour with Panama Canal and City Tour
£126
per adult
Frequently asked questions
How much does a La Mesa travel package cost?
From just £502. Yes, you read that right. Our La Mesa travel packages are the best way to stretch your budget further. Bundle your favourite hotels, flights and car rentals and get out and see this exciting destination.
If I'm not able to travel, can I cancel my La Mesa travel package?
Plans can change suddenly, so yes, you can. You may be able to change or cancel your La Mesa travel package at no cost if you've booked in the last 24 hours. For older bookings, you can still cancel and rebook, but your airline, hotel or car rental company may charge additional fees. Need more information? Check out our Customer Service Portal. We're here to help make sure your trip goes off without a hitch.
How do I get a cheap travel package to La Mesa?
One of the easiest ways to save dollars (and time) is to bundle your bookings with Expedia. Hotels, rental cars, flights and activities — we've got everything you need. Pick a combination that suits your style and watch your savings stack up. We know a package deal is never one-size-fits-all. That's why we offer more than 550 air carriers and 1,000,000 hotel options across the world, which lets you customize your La Mesa getaway.
Does Expedia offer Book Now, Pay Later La Mesa holidays?
Your bank balance shouldn't prevent you from going on holiday, so Expedia has worked out a solution to help. Now that we've teamed up with online lender Klarna, it's easier than ever to book a terrific getaway without hurting your hip pocket. Klarna offers flexible payment options during the checkout process that take the stress out of budgeting for your escape. Check out these flexible payment options:
- Pay monthly holidays: Escape on that dream holiday sooner with Klarna's convenient monthly instalment plans. If paying just a little each month works for you, choose this option at checkout.
- Pay in instalments holidays: With this Book Now, Pay Later option, Klarna allows you to pay for your trip over multiple transactions.
- Low deposit holidays: If paying a small percentage of your getaway (rather than the full total upfront) makes it easier to click that "book now" button, go for a low deposit holiday payment plan from Klarna.
What are the top hotels in La Mesa?
If it's your very first time in La Mesa, book a room at Casa Mahana At Kalu Yala or The Camp At Kalu Yala. Both will make you feel at home and are favourites among many travellers.
How far in advance should I book my La Mesa holiday?
To score discount prices, book early. Airlines typically release tickets, along with some of the lowest fares, nearly a year in advance. Hotels, experiences and car rental should also be booked early so you can have the pick of the bunch. If you've decided on a last-minute getaway in La Mesa, there are always lots of great deals to be had on Expedia. Book something in today!
What does an Expedia La Mesa travel package include?
Packages include flights, hotels and rental cars, but you can mix and match them to create your ideal La Mesa escape. You can also add on a few activities and experiences once you've made your booking. You're in the driver's seat! When you bundle your bookings with Expedia, you'll get discounts you won't find anywhere else.
What should I know before booking a La Mesa travel package?
Booking all the parts of your holiday together is a simple way to save. Combine your airfares, rental cars and hotels into a neat little package. But it's not just hotels. Expedia offers all types of properties, including holiday rentals such as beachfront villas and city apartments. You've got choices galore!
Can I choose my airline with a La Mesa Expedia travel package?
Expedia has access to more than 550 partner airlines globally, so you definitely can. Just select the carrier you want and craft the perfect La Mesa escape.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.
