La Mesa Holidays from £443

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Top La Mesa Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
MARINN Tropical Vibes Hotel

MARINN Tropical Vibes Hotel

3.5 out of 5
Amador
Price was £642, price is now £443 per person
£443
per person
18 Sept - 24 Sept
found 1 day ago
Return flight included
Port of Spain (POS) to Panama City (PTY)
8.2/10 Very Good! (119 reviews)
Spot is great for those who want to stay away from the city and bustle of the large crowd and stay more with the locals. There were areas for tourists like the slingshot tour and stops for hop on hop off bus, but it was mainly for locals to enjoy night life! Which I personally enjoyed. Great spot, I would just have to comment on the noise level being pretty high till 2am and the bed was slightly more firm for my taste. Overall, I would recommend this stay if you’re looking for a budget friendly option that is also nice!

Reviewed on 16 Aug 2025

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Save 100% on your flight
Price was £1,346, price is now £800 per person
£800
per person
18 Sept - 24 Sept
found 1 day ago
Return flight included
Port of Spain (POS) to Panama City (PTY)
9/10 Wonderful! (965 reviews)
Perfectly located for seeing Casco Viejo, and beautifully maintained as an historic building. Staff was absolutely accommodating and responsive to all requests (and we had a few!).

Reviewed on 18 Aug 2025

Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Punta Paitilla
Price was £863, price is now £595 per person
£595
per person
18 Sept - 24 Sept
found 1 day ago
Return flight included
Port of Spain (POS) to Panama City (PTY)
8.4/10 Very Good! (997 reviews)
This hotel is amazing and packed with culture, its beautiful, smells reallly nice and the views from the room is breathtaking!!! The room was very clean!!

Reviewed on 18 Aug 2025

MARINN PLACE Financial District

MARINN PLACE Financial District

3.5 out of 5
Bella Vista
Price was £971, price is now £676 per person
£676
per person
18 Sept - 24 Sept
found 1 day ago
Return flight included
Port of Spain (POS) to Panama City (PTY)
9.2/10 Wonderful! (290 reviews)
Friendly staff. Helped with airport transportation for an overnight layover

Reviewed on 24 Jul 2025

Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
Punta Paitilla
Price was £864, price is now £608 per person
£608
per person
18 Sept - 24 Sept
found 1 day ago
Return flight included
Port of Spain (POS) to Panama City (PTY)
8.8/10 Excellent! (1,004 reviews)
This property is in a great location in Panama City. It's easy and cheap to Uber to the MultiPlaza. The Union Market in the hotel has a great variety of food from sushi to traditional Panamanian to American and to Italian. The staff is super friendly. Sono Spa is also great. I had a facial and sauna treatment for $120. I also had the best view of the cork screw building and the city from my room on the 20th floor. Chau!

Reviewed on 17 Aug 2025

La Mesa Essential Information

Language
Spanish
Currency
Panamanian balboas
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Tocumen Intl. Airport (PTY)
Population
1,450
Max Temp Winter
29ºC
Max Temp Summer
29ºC
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

What to do in La Mesa

Eco Agro Adventure with Horseback Riding in a Private Ranch

Eco Agro Adventure with Horseback Riding in a Private Ranch

£56
per adult
Eco Agro Adventure with Horseback Riding in a Private Ranch
Amador Causeway

Private tour of Panama City and visit to the Miraflores Locks

£49
per adult
100% of travellers recommend
Private tour of Panama City and visit to the Miraflores Locks
Panama: Stopover City Tour, Canal visit with a Local Guide

Panama: Stopover City Tour, Canal visit with a Local Guide

£56
per adult
Panama: Stopover City Tour, Canal visit with a Local Guide
See all activities in La Mesa

Frequently asked questions

How much does a La Mesa travel package cost?
From just £443. Yes, you read that right. Our La Mesa travel packages are the best way to stretch your budget further. Bundle your favourite hotels, flights and car rentals and get out and see this exciting destination.
If I'm not able to travel, can I cancel my La Mesa travel package?
Plans can change suddenly, so yes, you can. You may be able to change or cancel your La Mesa travel package at no cost if you've booked in the last 24 hours. For older bookings, you can still cancel and rebook, but your airline, hotel or car rental company may charge additional fees. Need more information? Check out our Customer Service Portal. We're here to help make sure your trip goes off without a hitch.
How do I get a cheap travel package to La Mesa?
One of the easiest ways to save dollars (and time) is to bundle your bookings with Expedia. Hotels, rental cars, flights and activities — we've got everything you need. Pick a combination that suits your style and watch your savings stack up. We know a package deal is never one-size-fits-all. That's why we offer more than 550 air carriers and 1,000,000 hotel options across the world, which lets you customize your La Mesa getaway.
Does Expedia offer Book Now, Pay Later La Mesa holidays?
Your bank balance shouldn't prevent you from going on holiday, so Expedia has worked out a solution to help. Now that we've teamed up with online lender Klarna, it's easier than ever to book a terrific getaway without hurting your hip pocket. Klarna offers flexible payment options during the checkout process that take the stress out of budgeting for your escape. Check out these flexible payment options:

  • Pay monthly holidays: Escape on that dream holiday sooner with Klarna's convenient monthly instalment plans. If paying just a little each month works for you, choose this option at checkout.
  • Pay in instalments holidays: With this Book Now, Pay Later option, Klarna allows you to pay for your trip over multiple transactions.
  • Low deposit holidays: If paying a small percentage of your getaway (rather than the full total upfront) makes it easier to click that "book now" button, go for a low deposit holiday payment plan from Klarna.

What are the top hotels in La Mesa?
If it's your very first time in La Mesa, book a room at Casa Mahana At Kalu Yala or The Camp At Kalu Yala. Both will make you feel at home and are favourites among many travellers.
How far in advance should I book my La Mesa holiday?
To score discount prices, book early. Airlines typically release tickets, along with some of the lowest fares, nearly a year in advance. Hotels, experiences and car rental should also be booked early so you can have the pick of the bunch. If you've decided on a last-minute getaway in La Mesa, there are always lots of great deals to be had on Expedia. Book something in today!
What does an Expedia La Mesa travel package include?
Packages include flights, hotels and rental cars, but you can mix and match them to create your ideal La Mesa escape. You can also add on a few activities and experiences once you've made your booking. You're in the driver's seat! When you bundle your bookings with Expedia, you'll get discounts you won't find anywhere else.
What should I know before booking a La Mesa travel package?
Booking all the parts of your holiday together is a simple way to save. Combine your airfares, rental cars and hotels into a neat little package. But it's not just hotels. Expedia offers all types of properties, including holiday rentals such as beachfront villas and city apartments. You've got choices galore!
Can I choose my airline with a La Mesa Expedia travel package?
Expedia has access to more than 550 partner airlines globally, so you definitely can. Just select the carrier you want and craft the perfect La Mesa escape.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.