La Mesa Holidays

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to £750 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Packages with flights are ATOL protected

La Mesa Essential Information

Language
Spanish
Currency
Panamanian balboas
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Tocumen Intl. Airport (PTY)
Population
1,450
Max Temp Winter
29ºC
Max Temp Summer
29ºC

Top hotels in La Mesa

Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz Tocumen Panama
Fully refundable
The price is £93 per night from 27 Jul to 28 Jul
£93
27 Jul - 28 Jul
includes taxes & fees
8.6/10 Excellent! (2,622 reviews)
"Clean room"

Reviewed on 10 Jul 2026

Crowne Plaza Panama Airport by IHG
Aloft by Marriott Panama

Aloft by Marriott Panama

3.5 out of 5
Via Israel & Calle 76 Panama City Panama
Fully refundableReserve now, pay when you stay
The price is £100 per night from 25 Jul to 26 Jul
£100
25 Jul - 26 Jul
includes taxes & fees
8.8/10 Excellent! (1,010 reviews)
"Everyone was really nice and helpful"

Reviewed on 8 Jul 2026

Aloft by Marriott Panama
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street Panama City Panama
Fully refundableReserve now, pay when you stay
The price is £126 per night from 27 Jul to 28 Jul
£126
27 Jul - 28 Jul
includes taxes & fees
8.6/10 Excellent! (1,007 reviews)
"Convention going on but i had to ask to be compensated for all of the congestion and inconvenience and the manager complied. Well done for customer (me)."

Reviewed on 9 Jul 2026

Sheraton Grand Panama
See all 538 properties in La Mesa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

What to do in La Mesa

Amador Causeway

Private tour of Panama City and visit to the Miraflores Locks

£50
per adult
100% of travellers recommend
Private tour of Panama City and visit to the Miraflores Locks
Miraflores visitor center Platform view

Panama Canal Layover Tour

£83
per adult
Panama Canal Layover Tour
Eco Agro Adventure with Horseback Riding in a Private Ranch

Eco Agro Adventure with Horseback Riding in a Private Ranch

£57
per adult
Eco Agro Adventure with Horseback Riding in a Private Ranch
See all activities in La Mesa

Frequently asked questions

How much does a La Mesa travel package cost?
From just . Yes, you read that right. Our La Mesa travel packages are the best way to stretch your budget further. Bundle your favourite hotels, flights and car rentals and get out and see this exciting destination.
If I'm not able to travel, can I cancel my La Mesa travel package?
Plans can change suddenly, so yes, you can. You may be able to change or cancel your La Mesa travel package at no cost if you've booked in the last 24 hours. For older bookings, you can still cancel and rebook, but your airline, hotel or car rental company may charge additional fees. Need more information? Check out our Customer Service Portal. We're here to help make sure your trip goes off without a hitch.
How do I get a cheap travel package to La Mesa?
One of the easiest ways to save dollars (and time) is to bundle your bookings with Expedia. Hotels, rental cars, flights and activities — we've got everything you need. Pick a combination that suits your style and watch your savings stack up. We know a package deal is never one-size-fits-all. That's why we offer more than 550 air carriers and 1,000,000 hotel options across the world, which lets you customize your La Mesa getaway.
Does Expedia offer Book Now, Pay Later La Mesa holidays?
Your bank balance shouldn't prevent you from going on holiday, so Expedia has worked out a solution to help. Now that we've teamed up with online lender Klarna, it's easier than ever to book a terrific getaway without hurting your hip pocket. Klarna offers flexible payment options during the checkout process that take the stress out of budgeting for your escape. Check out these flexible payment options:

  • Pay monthly holidays: Escape on that dream holiday sooner with Klarna's convenient monthly instalment plans. If paying just a little each month works for you, choose this option at checkout.
  • Pay in instalments holidays: With this Book Now, Pay Later option, Klarna allows you to pay for your trip over multiple transactions.
  • Low deposit holidays: If paying a small percentage of your getaway (rather than the full total upfront) makes it easier to click that "book now" button, go for a low deposit holiday payment plan from Klarna.

What are the top hotels in La Mesa?
If it's your very first time in La Mesa, book a room at Casa Mahana At Kalu Yala or The Camp At Kalu Yala. Both will make you feel at home and are favourites among many travellers.
How far in advance should I book my La Mesa holiday?
To score discount prices, book early. Airlines typically release tickets, along with some of the lowest fares, nearly a year in advance. Hotels, experiences and car rental should also be booked early so you can have the pick of the bunch. If you've decided on a last-minute getaway in La Mesa, there are always lots of great deals to be had on Expedia. Book something in today!
What does an Expedia La Mesa travel package include?
Packages include flights, hotels and rental cars, but you can mix and match them to create your ideal La Mesa escape. You can also add on a few activities and experiences once you've made your booking. You're in the driver's seat! When you bundle your bookings with Expedia, you'll get discounts you won't find anywhere else.
What should I know before booking a La Mesa travel package?
Booking all the parts of your holiday together is a simple way to save. Combine your airfares, rental cars and hotels into a neat little package. But it's not just hotels. Expedia offers all types of properties, including holiday rentals such as beachfront villas and city apartments. You've got choices galore!
Can I choose my airline with a La Mesa Expedia travel package?
Expedia has access to more than 550 partner airlines globally, so you definitely can. Just select the carrier you want and craft the perfect La Mesa escape.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.