Title: Hotels in La Mesa - Best La Mesa Hotels from £39 - Fully Refundable Options - Expedia.co.uk [Holiday Rentals in La Mesa](https://expedia.co.uk/La-Mesa-Holiday-Rentals.d553248635975862472.Travel-Guide-HolidayRentals)[La Mesa Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-La-Mesa.d553248635975862472.Car-Hire-Guide)[La Mesa Holidays](https://expedia.co.uk/La-Mesa.d553248635975862472.Holidays-City-Breaks) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in La Mesa from £39 ![price find illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in La Mesa Apart­ment [](https://www.expedia.co.uk/Hotel-Search?destination=La+Mesa%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248635975862472&latLong=9.167865%2C-79.281738&adults=2&startDate=2025-10-19&d1=2025-10-19&endDate=2025-10-21&d2=2025-10-21&lodging=APARTMENT) Pool [](https://www.expedia.co.uk/Hotel-Search?destination=La+Mesa%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248635975862472&latLong=9.167865%2C-79.281738&adults=2&startDate=2025-10-19&d1=2025-10-19&endDate=2025-10-21&d2=2025-10-21&amenities=POOL) Cabin [](https://www.expedia.co.uk/Hotel-Search?destination=La+Mesa%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248635975862472&latLong=9.167865%2C-79.281738&adults=2&startDate=2025-10-19&d1=2025-10-19&endDate=2025-10-21&d2=2025-10-21&lodging=CABIN) Sea view [](https://www.expedia.co.uk/Hotel-Search?destination=La+Mesa%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248635975862472&latLong=9.167865%2C-79.281738&adults=2&startDate=2025-10-19&d1=2025-10-19&endDate=2025-10-21&d2=2025-10-21&amenities=OCEAN_VIEW) Family friendly [](https://www.expedia.co.uk/Hotel-Search?destination=La+Mesa%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248635975862472&latLong=9.167865%2C-79.281738&adults=2&startDate=2025-10-19&d1=2025-10-19&endDate=2025-10-21&d2=2025-10-21&travelerType=family_friendly) Pet friendly [](https://www.expedia.co.uk/Hotel-Search?destination=La+Mesa%2C+Panam%C3%A1+Province%2C+Panama®ionId=553248635975862472&latLong=9.167865%2C-79.281738&adults=2&startDate=2025-10-19&d1=2025-10-19&endDate=2025-10-21&d2=2025-10-21&amenities=PETS) ## Check prices for these dates Tonight [4 Oct - 5 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975862472&startDate=2025-10-04&endDate=2025-10-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [5 Oct - 6 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975862472&startDate=2025-10-05&endDate=2025-10-06&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [10 Oct - 12 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975862472&startDate=2025-10-10&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [17 Oct - 19 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248635975862472&startDate=2025-10-17&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top 10 La Mesa hotels and places to stay ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/877d081d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/da7a9306.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/6010dc9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout curtains, soundproofing](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/3873c049.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Crowne Plaza Panama Airport by IHG Tocumen 8.4/10 Very good (2231) "near airport, staff super helpful " £96 includes taxes & fees 5 Nov - 6 Nov [](https://www.expedia.co.uk/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information) ![Outdoor pool, open 7:00 AM to 10:30 PM, free pool cabanas](https://images.trvl-media.com/lodging/1000000/30000/26300/26240/b7e843b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sports facility](https://images.trvl-media.com/lodging/1000000/30000/26300/26240/04f50e95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, down duvets, in-room safe](https://images.trvl-media.com/lodging/1000000/30000/26300/26240/533cc611.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/30000/26300/26240/ea26a97c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Riande Aeropuerto Hotel & Casino Tocumen 8.6/10 Excellent (1895) "Nice hotel, close to the airport, friendly staff" £122 includes taxes & fees 10 Oct - 11 Oct [](https://www.expedia.co.uk/Tocumen-Hotels-Riande-Aeropuerto-Hotel-Casino.h26240.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/7000000/6580000/6577500/6577427/75c7ddd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/7000000/6580000/6577500/6577427/a87f2f0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/7000000/6580000/6577500/6577427/4a3f7176.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![aloft, Suite, 2 Queen Beds, City View | Living room | 42-inch LED TV with digital channels, TV, pay films](https://images.trvl-media.com/lodging/7000000/6580000/6577500/6577427/8e89de30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aloft Panama San Francisco 8.6/10 Excellent (860) "We stayed here for a week and it was filled with happy staff who were very courteous ! They made sure we were taken care of at all times and I will stay here again when we return. " £95 includes taxes & fees 11 Oct - 12 Oct [](https://www.expedia.co.uk/Panama-City-Hotels-Aloft-Panama.h6577427.Hotel-Information) ![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/5000000/4320000/4316400/4316336/w3989h2656x0y8-13f5112b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/5000000/4320000/4316400/4316336/c67d7481.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/5000000/4320000/4316400/4316336/9d48c90f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Serves breakfast, lunch and dinner](https://images.trvl-media.com/lodging/5000000/4320000/4316400/4316336/cd4ab84d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Panama Metromall Cerro Viento 8.8/10 Excellent (1002) "Always a great hotel, forth time back" £87 includes taxes & fees 1 Nov - 2 Nov [](https://www.expedia.co.uk/San-Miguelito-Hotels-Courtyard-By-Marriott-Panama-Metromall.h4316336.Hotel-Information) ![Suite, 1 Bedroom, Non Smoking, Golf View (Terrace) | Premium bedding, minibar, in-room safe, desk](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/d80494b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/2a51fa85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/1e4d9048.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/c77947e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City Juan Diaz 9.6/10 Exceptional (612) "great service" £180 includes taxes & fees 11 Oct - 12 Oct [](https://www.expedia.co.uk/Panama-City-Hotels-The-Santa-Maria.h20958573.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/7000000/6470000/6461100/6461097/a9059efb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/7000000/6470000/6461100/6461097/9c6b201c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/7000000/6470000/6461100/6461097/6a6aadb8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/7000000/6470000/6461100/6461097/73a42da0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Express Inn Panama International Airport Hostel Tocumen 6.0/10 (632) "Perfect for a quick overnight before a flight out of PTY or a land and rest location. " £40 includes taxes & fees 6 Oct - 7 Oct [](https://www.expedia.co.uk/Tocumen-Hotels-Express-Inn-Panama-International-Airport-Hostel.h6461097.Hotel-Information) ![1 bedroom, laptop workspace, soundproofing, free WiFi](https://images.trvl-media.com/lodging/39000000/38720000/38713000/38712982/6dc250bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/39000000/38720000/38713000/38712982/2a230d8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, laptop workspace, soundproofing, free WiFi](https://images.trvl-media.com/lodging/39000000/38720000/38713000/38712982/50019413.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Quadruple Room | 1 bedroom, laptop workspace, soundproofing, free WiFi](https://images.trvl-media.com/lodging/39000000/38720000/38713000/38712982/cf61e7af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### B&B Lodgings 24 de Diciembre 7.8/10 Good (68) "I givethis rating of five stars because Daisy the owner, is so wonderful. I ended up checking in late. She helped me order food. She was very very accommodating. Her English is very good. The room that I stayed in was very clean and had everything that you would need. I will stay there again When I will have to stay in Panama City. The grounds are absolutely beautiful." £39 includes taxes & fees 11 Oct - 12 Oct [](https://www.expedia.co.uk/Tocumen-Hotels-BB-Lodgings.h38712982.Hotel-Information) ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/9000000/8220000/8217000/8216939/803aefa9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property – evening/night](https://images.trvl-media.com/lodging/9000000/8220000/8217000/8216939/49d1f8ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/9000000/8220000/8217000/8216939/f3139092.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/9000000/8220000/8217000/8216939/7d8fcf8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ramada Plaza by Wyndham Panama Punta Pacifica San Francisco 9.6/10 Exceptional (1059) "Family-friendly hotel, tasty breakfast options daily and overall friendly staff and clean space." £89 includes taxes & fees 6 Oct - 7 Oct [](https://www.expedia.co.uk/Panama-City-Hotels-Ramada-Plaza-By-Wyndham-Panama-Punta-Pacifica.h8216939.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/179e52b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 restaurants, breakfast served](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/1f8c9ffe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment room(s), sauna, hot tub, Turkish bath/hammam](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/19f9d9c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/25adc131.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sheraton Grand Panama San Francisco 8.6/10 Excellent (962) "Relaxing but close by to everything " £109 includes taxes & fees 12 Oct - 13 Oct [](https://www.expedia.co.uk/Panama-City-Hotels-Sheraton-Grand-Panama.h1161.Hotel-Information) ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/6000000/5790000/5781900/5781845/2aa9e1b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillow-top beds, minibar, in-room safe](https://images.trvl-media.com/lodging/6000000/5790000/5781900/5781845/dd688b9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/6000000/5790000/5781900/5781845/eff56d3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Banquet hall](https://images.trvl-media.com/lodging/6000000/5790000/5781900/5781845/8ad18c08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Westin Panama Costa del Este 8.8/10 Excellent (295) "Hotel was great and the staff was amazing " £153 includes taxes & fees 31 Oct - 1 Nov [](https://www.expedia.co.uk/Panama-City-Hotels-The-Westin-Panama.h5781845.Hotel-Information) ![Living area](https://images.trvl-media.com/lodging/120000000/119870000/119860600/119860522/febf3b4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/120000000/119870000/119860600/119860522/d1a4e6a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/120000000/119870000/119860600/119860522/c164ba0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee shop](https://images.trvl-media.com/lodging/120000000/119870000/119860600/119860522/c8d2e545.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### ORHO HOTEL BOUTIQUE PANAMA Airport Tocumen 8.4/10 Very good (7) "Very nice boutique hotel" £93 includes taxes & fees 6 Oct - 7 Oct [](https://www.expedia.co.uk/Tocumen-Hotels-ORHO-HOTEL-BOUTIQUE-PANAMA-Airport.h119860522.Hotel-Information) ![50-inch LED TV with satellite channels](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/dbfa0534.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/4e9d4ce1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment, 2 Bedrooms | 1 bedroom, premium bedding, in-room safe, cots/infant beds](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/f6eaf73a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/81f325e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Arcadia Condo Suites Costa del Este 9.2/10 Wonderful (89) "Wonderful place great staff " £77 includes taxes & fees 4 Nov - 5 Nov [](https://www.expedia.co.uk/Panama-City-Hotels-Arcadia-Condo-Suites.h104456900.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/b51e58b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/a3d62646.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/ed9d8c5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms | Living area | 32-inch Smart TV with digital channels, TV, Netflix](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/48e220ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Boutique Apartments Panamá Coco del Mar San Francisco 7.6/10 Good (137) "Beautiful view! " £132 includes taxes & fees 6 Oct - 7 Oct [](https://www.expedia.co.uk/Panama-City-Hotels-Boutique-Apartments-Panama-Coco-Del-Mar.h88675323.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/b12b577d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (8B) | Private kitchen | Fridge, microwave, oven, toaster](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/b8e57e7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (17B) | 2 bedrooms, free WiFi, bed sheets](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/155ac5ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/4f5c676f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Boutique Apartments Atlapa San Francisco 7.4/10 Good (21) "I had an excellent stay here ! It was a very amazing the host is an amazing person thank you for making My stay great❤️" [](https://www.expedia.co.uk/Panama-City-Hotels-Boutique-Apartments-Atlapa.h91495486.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/101000000/100530000/100525500/100525493/1940e046.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (09H) | Living area | 55-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/101000000/100530000/100525500/100525493/e1902a90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (11B) | Balcony](https://images.trvl-media.com/lodging/101000000/100530000/100525500/100525493/w2996h2000x4y0-ef85e67f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (11I) | 1 bedroom, down duvets, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/101000000/100530000/100525500/100525493/0f7befd4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### San Francisco by Wynwood House San Francisco 9.2/10 Wonderful (50) "Good comfy rooms" £116 includes taxes & fees 6 Oct - 7 Oct [](https://www.expedia.co.uk/Panama-City-Hotels-Living-By-Wynwood-House.h100525493.Hotel-Information) ![Apartment, 3 Bedrooms, Accessible, Pool View | Children’s area](https://images.trvl-media.com/lodging/120000000/119470000/119462200/119462129/w2048h1520x0y0-47515268.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 3 Bedrooms, Accessible, Pool View | Interior](https://images.trvl-media.com/lodging/120000000/119470000/119462200/119462129/5864a396.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 3 Bedrooms, Accessible, Pool View | 3 bedrooms](https://images.trvl-media.com/lodging/120000000/119470000/119462200/119462129/6373d836.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 3 Bedrooms, Accessible, Pool View | Interior](https://images.trvl-media.com/lodging/120000000/119470000/119462200/119462129/c4449701.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Apto 3-hab-piscina-15 Tocumen Min-airport José Domingo Espinar £59 includes taxes & fees 6 Oct - 7 Oct [](https://www.expedia.co.uk/San-Miguelito-Hotels-Apto-3-Hab-Piscina-15-Tocumen-Min-Airport.h119462129.Hotel-Information) ![Apartment | Internet](https://images.trvl-media.com/lodging/120000000/119330000/119325200/119325173/9ab6cebb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | Internet](https://images.trvl-media.com/lodging/120000000/119330000/119325200/119325173/da705e38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | Internet](https://images.trvl-media.com/lodging/120000000/119330000/119325200/119325173/w3000h1936x0y0-cbee8bba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | Internet](https://images.trvl-media.com/lodging/120000000/119330000/119325200/119325173/f1366299.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### w Bright 1BR w Private Balcony in San Francisco San Francisco £102 includes taxes & fees 26 Oct - 27 Oct [](https://www.expedia.co.uk/Panama-City-Hotels-W-Bright-1BR-W-Private-Balcony-In-San-Francisco.h119325173.Hotel-Information) ![2 bedrooms](https://images.trvl-media.com/lodging/121000000/120200000/120194500/120194409/956acab5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 1 Bedroom, Balcony | Interior](https://images.trvl-media.com/lodging/121000000/120200000/120194500/120194409/5f25d036.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 1 Bedroom, Balcony | Dining](https://images.trvl-media.com/lodging/121000000/120200000/120194500/120194409/65d48e93.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 1 Bedroom, Balcony | Private kitchen](https://images.trvl-media.com/lodging/121000000/120200000/120194500/120194409/0cc1441a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Swette Love 10 Minutes From the Airport Tocumen Las Mañanitas £54 includes taxes & fees 15 Oct - 16 Oct [](https://www.expedia.co.uk/Las-Mananitas-Hotels-Swette-Love-10-Minutes-From-The-Airport-Tocumen.h120194409.Hotel-Information) ![Apartment | 1 bedroom, Internet](https://images.trvl-media.com/lodging/120000000/119090000/119080600/119080509/1f70dfc5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | 1 bedroom, Internet](https://images.trvl-media.com/lodging/120000000/119090000/119080600/119080509/77c2cbdd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | 1 bedroom, Internet](https://images.trvl-media.com/lodging/120000000/119090000/119080600/119080509/4c52aa30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | 1 bedroom, Internet](https://images.trvl-media.com/lodging/120000000/119090000/119080600/119080509/c16d0930.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### w Premium 1BR w Balcony in San Francisco San Francisco £103 includes taxes & fees 27 Oct - 28 Oct [](https://www.expedia.co.uk/Panama-City-Hotels-W-Premium-1BR-W-Balcony-In-San-Francisco.h119080509.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-19&endDate=2025-10-20®ionId=553248635975862472&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FLa-Mesa-Hotels.d553248635975862472.Travel-Guide-Hotels)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FLa-Mesa-Hotels.d553248635975862472.Travel-Guide-Hotels) ## Top La Mesa Hotel Reviews ![Arcadia Condo Suites](//images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/dbfa0534_y.jpg) ### Arcadia Condo Suites 10/10 Excellent "Wonderful place great staff " [](https://expedia.co.uk/Panama-City-Hotels-Arcadia-Condo-Suites.h104456900.Hotel-Information) ![Crowne Plaza Panama Airport by IHG](//images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/877d081d_y.jpg) ### Crowne Plaza Panama Airport by IHG 10/10 Excellent "Great location " [](https://expedia.co.uk/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information) ![The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City](//images.trvl-media.com/lodging/21000000/20960000/20958600/20958573/d80494b9_y.jpg) ### The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City 10/10 Excellent "Clean, well designed rooms. Soft king bed and pillows, desk, nice shower with rain showerhead. Golf course was hard to navigate without knowing itslayout as a visitor, but nice course though. Wish there was more casual resturants open by pool on Sundays or anyday for relaxing time. More formal dress inside hotel and restaurants. Helen in the Spa offered great pedi/manicare/nail services. Quality food in restaurants. Many staff members are bi lingual. US prices in this resort. 5 star stay. " [](https://expedia.co.uk/Panama-City-Hotels-The-Santa-Maria.h20958573.Hotel-Information) ![Courtyard by Marriott Panama Metromall](//images.trvl-media.com/lodging/5000000/4320000/4316400/4316336/w3989h2656x0y8-13f5112b_y.jpg) ### Courtyard by Marriott Panama Metromall 10/10 Excellent "Staff very helpful! I enjoyed the gym and pool. Good pizza in the restaurant." [](https://expedia.co.uk/San-Miguelito-Hotels-Courtyard-By-Marriott-Panama-Metromall.h4316336.Hotel-Information) ![Sheraton Grand Panama](//images.trvl-media.com/lodging/1000000/10000/1200/1161/179e52b4_y.jpg) ### Sheraton Grand Panama 10/10 Excellent "Enjoyed my stay. Especially loved the gym. I will be back." [](https://expedia.co.uk/Panama-City-Hotels-Sheraton-Grand-Panama.h1161.Hotel-Information) ![Riande Aeropuerto Hotel & Casino](//images.trvl-media.com/lodging/1000000/30000/26300/26240/b7e843b8_y.jpg) ### Riande Aeropuerto Hotel & Casino 10/10 Excellent "The property was always clean and maintained well especially room service@" [](https://expedia.co.uk/Tocumen-Hotels-Riande-Aeropuerto-Hotel-Casino.h26240.Hotel-Information) ![San Francisco by Wynwood House ](//images.trvl-media.com/lodging/101000000/100530000/100525500/100525493/1940e046_y.jpg) ### San Francisco by Wynwood House 10/10 Excellent "The apartment was clean and had all that is needed for daily convenience with much storage. Staff was friendly and quite helpful to us. Construction nereby was a bit disturbing for us but thats temporary so shouldn't be a bother after its completion. Would definitely recommend." [](https://expedia.co.uk/Panama-City-Hotels-Living-By-Wynwood-House.h100525493.Hotel-Information) ![Express Inn Panama International Airport Hostel](//images.trvl-media.com/lodging/7000000/6470000/6461100/6461097/a9059efb_y.jpg) ### Express Inn Panama International Airport Hostel 10/10 Excellent "Todo sin problemas muy amables Nos trajeron al aeropuerto tienen servio de traslado gratis" [](https://expedia.co.uk/Tocumen-Hotels-Express-Inn-Panama-International-Airport-Hostel.h6461097.Hotel-Information) ![Ocean-view Luxe 2-Bedroom at Magnificent Wanders Yoo, Ave Balboa, Panama City!](//images.trvl-media.com/lodging/97000000/96970000/96963800/96963771/d88346c3_y.jpg) ### Ocean-view Luxe 2-Bedroom at Magnificent Wanders Yoo, Ave Balboa, Panama City! 10/10 Excellent "New building with wonderful amenities. The unit was nicely furnished, clean, and had wonderful ocean views. At the time it lacked window shades, which made for intense early morning light, but after speaking with the manager they agreed to install them for future guests. " [](https://expedia.co.uk/Panama-City-Hotels-Ocean-View-Luxe-2-Bedroom-At-Magnificent-Wanders-Yoo.h96963771.Hotel-Information) ## More cheap stays in La Mesa ![Arcadia Condo Suites](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/dbfa0534_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Arcadia Condo Suites Calle rio mar, Panama City, Panamá Province £77 4 Nov - 5 Nov includes taxes & fees 9.2/10 Wonderful! (88 reviews) [](https://expedia.co.uk/Panama-City-Hotels-Arcadia-Condo-Suites.h104456900.Hotel-Information) ![B&B Lodgings](https://images.trvl-media.com/lodging/39000000/38720000/38713000/38712982/6dc250bd_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### B&B Lodgings C. Tercera El Valle de Cerro Azul, 24 de Diciembre, Panamá Province £39 11 Oct - 12 Oct includes taxes & fees 7.6/10 Good! (69 reviews) [](https://expedia.co.uk/Tocumen-Hotels-BB-Lodgings.h38712982.Hotel-Information) ![Apartment in San Francisco](https://images.trvl-media.com/lodging/110000000/109210000/109203500/109203460/fd14bd54_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Apartment in San Francisco Panama City, Panamá Province £89 6 Oct - 7 Oct includes taxes & fees 8/10 Very Good! (1 review) [](https://expedia.co.uk/Panama-City-Hotels-Apartment-In-San-Francisco.h109203460.Hotel-Information) ![Blue Dream in San Francisco](https://images.trvl-media.com/lodging/114000000/113940000/113939800/113939742/b75a1c95_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Blue Dream in San Francisco Panama City [Get rates](https://expedia.co.uk/Hotel-Search?startDate=19%2F10%2F2025&endDate=20%2F10%2F2025&selected=113939742&PinnedHotelID=113939742&HadPinnedHotel=true®ionId=553248635975862472) [](https://expedia.co.uk/Panama-City-Hotels-Blue-Dream-In-San-Francisco.h113939742.Hotel-Information) ![w* | Refined 1BR w/ Balcony in San Francisco](https://images.trvl-media.com/lodging/106000000/105990000/105988100/105988089/b4d540ee_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### w\* | Refined 1BR w/ Balcony in San Francisco Panamá, Panama £103 27 Oct - 28 Oct includes taxes & fees 8/10 Very Good! (1 review) [](https://expedia.co.uk/Panama-City-Hotels-W-Radiant-1BR-W-Modern-Balcony-In-San-Francisco.h105988089.Hotel-Information) ![The Camp at Kalu Yala](https://images.trvl-media.com/lodging/71000000/70850000/70847500/70847418/e2dc8d48_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### The Camp at Kalu Yala San Martín, San Martín, Panama Province [Get rates](https://expedia.co.uk/Hotel-Search?startDate=19%2F10%2F2025&endDate=20%2F10%2F2025&selected=70847418&PinnedHotelID=70847418&HadPinnedHotel=true®ionId=553248635975862472) [](https://expedia.co.uk/Kalu-Yala.h70847418.Hotel-Information) ## Explore a world of travel with Expedia - Explore a world of travel with Expedia ### Accommodation near La Mesa attractions - [Hotels near Chagres National Park](https://expedia.co.uk/Chagres-National-Park-Hotels.0-l6252818-0.Travel-Guide-Filter-Hotels) ### Hotels near La Mesa Airports - [Tocumen Intl. 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