Isla Santa María Holidays from £2,374

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Photo by Delen Wong

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Your Isla Santa María Holiday

Amazing adventures await when you reserve a holiday package to Isla Santa María. Whether you're a foodie, history buff or just a traveller who loves to experience new places, there's something for everyone in this lively city. Post Office Bay is one of the top attractions to include on your sightseeing agenda during a trip to Isla Santa María. Expedia is here to help you escape the everyday. Tailor your holiday to Isla Santa María to suit your travel style, whatever that may be.

Top Isla Santa María Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
Galapagos Native

Galapagos Native

3 out of 5
Price was £2,595, price is now £2,374 per person
£2,374
per person
2 Oct - 8 Oct
found 1 hour ago
Return flight included
London (LON) to Isla Baltra (GPS)
7.8/10 Good! (96 reviews)

BAY VIEW HOUSE

BAY VIEW HOUSE

3.5 out of 5
Price was £2,767, price is now £2,505 per person
£2,505
per person
2 Oct - 8 Oct
found 1 hour ago
Return flight included
London (LON) to Isla Baltra (GPS)
10/10 Exceptional! (6 reviews)
I had a wonderful stay at this Bay View House  in the Galápagos Islands. The location was excellent, with easy access to local attractions, restaurants, and the waterfront. The hotel was very clean, well-maintained, and comfortable. The staff was friendly and helpful throughout my stay. The rooms were spacious, quiet, and nicely furnished, making it a great place to relax after a day of exploring. I highly recommend this hotel to anyone visiting the Galápagos.

Reviewed on 9 Jun 2026

Angermeyer Waterfront Inn

Angermeyer Waterfront Inn

3.5 out of 5
Price was £2,888, price is now £2,667 per person
£2,667
per person
2 Oct - 8 Oct
found 1 hour ago
Return flight included
London (LON) to Isla Baltra (GPS)
9.4/10 Exceptional! (140 reviews)
Nicest place I’ve ever stayed. Staff greeted you with drinks, cold towel, and ac. Beautiful on water. Also next door had best pina colada I’ve ever had !

Reviewed on 29 Jun 2026

Hotel Isamar Galapagos Beachfront

Hotel Isamar Galapagos Beachfront

3.5 out of 5
Price was £2,772, price is now £2,570 per person
£2,570
per person
2 Oct - 8 Oct
found 1 hour ago
Return flight included
London (LON) to Isla Baltra (GPS)
9/10 Wonderful! (62 reviews)
Nice place on the beach, good walking distance to town, friendly staff, breakfast ok. Loved Isabela Island!

Reviewed on 17 Jun 2026

Hotel Albemarle Galapagos Beachfront

Hotel Albemarle Galapagos Beachfront

3.5 out of 5
Price was £2,697, price is now £2,512 per person
£2,512
per person
2 Oct - 8 Oct
found 1 hour ago
Return flight included
London (LON) to Isla Baltra (GPS)
9/10 Wonderful! (108 reviews)
Great place to stay. Very nice staff

Reviewed on 15 Jun 2026

Isla Santa Marían Essential Information

Language
Spanish
Currency
U.S dollars
Local Welcome
¡Hola!
Local Goodbye
Adiós

Top hotels in Isla Santa María

Hotel Fiesta

Hotel Fiesta

3.5 out of 5
Calle Moises Brito y Juan Montalvo Puerto Ayora Galapagos
Fully refundableReserve now, pay when you stay
The price is £104 per night from 7 Aug to 8 Aug
£104
7 Aug - 8 Aug
9/10 Wonderful! (421 reviews)
"My stay was amazing. From first entering the lobby where guest and staff were gathered to watch Ecuador advance in the World Cup. To the wonderful breakfast served by fantastic people. Front desk staff who help coordinate day trips, call taxi and provide great restaurant recommendations"

Reviewed on 8 Jul 2026

Hotel Fiesta
Hotel el descanso del Guia

Hotel el descanso del Guia

3.5 out of 5
Calle Delfin, Barrio el Mirador Puerto Ayora Galapagos
The price is £56 per night from 27 Jul to 28 Jul
£56
27 Jul - 28 Jul
8.8/10 Excellent! (217 reviews)
"Un lindo lugar, muy cerca del terminal."

Reviewed on 9 Jul 2026

Hotel el descanso del Guia
Finch Bay Galapagos Hotel

Finch Bay Galapagos Hotel

4.5 out of 5
Barrio Punta Estrada Puerto Ayora Galapagos
The price is £436 per night from 14 Jul to 15 Jul
£436
14 Jul - 15 Jul
9.4/10 Exceptional! (102 reviews)
"The staff and service are exceptional! The venue cannot be beaten. It’s the only place with a private beach. They have complementary water taxis that take you everywhere. When we got off our boat, they were waiting for us without us, even having to notify them. Definitely would recommend this hotel ..."

Reviewed on 4 Jul 2026

Finch Bay Galapagos Hotel
See all 219 properties in Isla Santa María
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Holidays
All Inclusive Holidays
Beach Holidays
Beach Holidays
Family Friendly Holidays
Family Friendly Holidays

Stay near popular Isla Santa María attractions

A sea turtle swimming underwater.
Photo by Tove Martin
Open Photo by Tove Martin

Post Office Bay

Commune with nature and explore the great outdoors at Post Office Bay during your travels in Isla Santa María. While you're in the area, wander around the natural setting.
See properties

What to do in Isla Santa María

Learn about the history of Floreana

Full Day Floreana Tour

£166
per adult
Full Day Floreana Tour
Full Day Santa Fe and Playa escondida with Snorkeling and lunch Included

Day Trip Santa Fe and Playa escondida with Snorkeling

£180
per adult
Day Trip Santa Fe and Playa escondida with Snorkeling
Faune seeing at the snorkeling

Full Day Santa Fe Playa escondida snorkeling tour

£173
per adult
Full Day Santa Fe Playa escondida snorkeling tour
See all activities in Isla Santa María

Frequently asked questions

How much does an Isla Santa María travel package cost?
Choose from any combination of flights, hotels and car rentals, and you can be holidaying in Isla Santa María from just £2,374. And the more you bundle, the more you save. The holiday of your dreams has never been more affordable.
If I'm not able to travel, can I cancel my Isla Santa María travel package?
You sure can, and we're here to help. You may be able to cancel or change your Isla Santa María travel package for free if you booked in the last 24 hours. However, you may be charged a fee by your airline, hotel or car rental company if you booked more than 24 hours ago. If your circumstances suddenly change, visit our Customer Service Portal for more information.
How do I get a cheap travel package to Isla Santa María?
Bundle your flights and hotels, throw in extras such as activities, and save with an Isla Santa María travel package. You won't just land big discounts on your adventure — you'll have lots of choice within your reach too. When you book through Expedia, you'll have your pick of over 550 airlines and 1,000,000 properties across the globe. Your next affordable adventure starts right here, right now!
Does Expedia offer Book Now, Pay Later Isla Santa María holidays?
Your bank balance shouldn't get in the way of going on holiday, so Expedia has worked out a solution to help. Thanks to our partnership with online lender Klarna, it's easier than ever to book a terrific getaway without hurting your hip pocket. Klarna offers flexible payment options at checkout that take the worry out of budgeting for your break. Consider one of these flexible payment options:

  • Pay monthly holidays: If paying bite-sized amounts each month sounds best for you, Klarna offers just that! Paying in convenient monthly instalments will make your holiday dreams come true.
  • Pay in instalments holidays: With this Book Now, Pay Later option, Klarna makes it possible to pay for your holiday over multiple transactions.
  • Low deposit holidays: If paying a small percentage of your getaway (rather than the full total upfront) makes it easier to click that "book now" button, go for a low deposit holiday payment plan from Klarna.

What are the top hotels in Isla Santa María?
Secure a room at Hotel Fiesta. It's one of the area's most in-demand properties. Another top-rated option in Isla Santa Marían is Blu Galapagos.
How far in advance should I book my Isla Santa María holiday?
Be rewarded with the widest variety at the cheapest prices by booking your trip to Isla Santa María nice and early. Airlines generally publish flight tickets around a year prior to departure, so start your planning as soon as possible. That being said, Expedia is dedicated to providing you with the best bargains around, so it's always a good time to book your dream holiday!
What does an Expedia Isla Santa María travel package include?
Rental cars, hotels and flights — you'll find them all here. With Expedia, you can create your Isla Santa María package just how you like it. All you have to do is figure out just what you need. Once you've made your booking, you can add extras like tours and activities. The more you bundle, the bigger your savings!
What should I know before booking an Isla Santa María travel package?
You can save a tidy sum by bundling your hotels, airfares and rental cars. Once you've made your booking, you can add on things like tours and activities. Your next awesome holiday is only a few clicks away.
Can I choose my airline with an Isla Santa Marían Expedia travel package?
You can, and with more than 550 airlines to select from globally, you have plenty of choice. Browse the available options and see which airline best fits your needs and budget.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.