Title: Isla Grande Holidays 2026 from £865 | Expedia.co.uk [Hotels in Isla Grande](https://expedia.co.uk/Isla-Grande-Hotels.d6053183.Travel-Guide-Hotels)[Holiday Rentals in Isla Grande](https://expedia.co.uk/Isla-Grande-Holiday-Rentals.d6053183.Travel-Guide-HolidayRentals)[Isla Grande Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Isla-Grande.d6053183.Car-Hire-Guide) ![](https://images.trvl-media.com/place/6053183/3ddb22e8-2245-453b-b3ca-3467e9b3943f.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Isla Grande Holidays from £865 ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to £335 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Packages with flights are ATOL protected #### Your Isla Grande Holiday With a Isla Grande holiday package, say goodbye to endless planning and hello to stress-free adventure. Every detail of your getaway has been taken care of before you go, so you can enjoy each moment discovering this lively city. If taking in the sights is a priority during your trip to Isla Grande, be sure to swing by famous attractions like [Isla Mamey](https://www.expedia.co.uk/Isla-Mamey-Colon.d553248623454093160.Attraction) and [Portobelo National Park](https://www.expedia.co.uk/Portobelo-National-Park-Colon.d6252836.Attraction). Whoever you're heading away with and whatever you want to spend, your dream Isla Grande holiday is just a few clicks away with Expedia. ## Top Isla Grande Flight + Hotel Deals Price found within the past 48 hours. Click for updated prices. ![Megapolis Hotel Panamá](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/4aee4896_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Megapolis Hotel Panamá San Francisco £865 per person 7 May - 10 May found 11 hours ago Return direct flight included London (LON) to Panama City (PTY) 8.4/10 Very Good! (1,437 reviews) View of the city but you can ask prior arrival your prefernce. Shops are nearby Reviewed on 2 Mar 2026 ![Central Hotel Panama Casco Viejo](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/786350eb_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Central Hotel Panama Casco Viejo Casco Viejo £965 per person 7 May - 10 May found 11 hours ago Return direct flight included London (LON) to Panama City (PTY) 9/10 Wonderful! (1,008 reviews) The staff was great an the hotel Reviewed on 2 Mar 2026 ![Casa Mallet by Wynwood House](https://images.trvl-media.com/lodging/100000000/99780000/99778900/99778891/67865bff_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Casa Mallet by Wynwood House Casco Viejo £1,006 per person 7 May - 10 May found 11 hours ago Return direct flight included London (LON) to Panama City (PTY) 9.8/10 Exceptional! (25 reviews) Beautiful apartment definitely recommend staying here if you are coming to Panama Reviewed on 29 Nov 2025 ![Dreams Playa Bonita Panama - All Inclusive](https://images.trvl-media.com/lodging/13000000/12450000/12445600/12445554/7c338453_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Dreams Playa Bonita Panama - All Inclusive £1,038 per person 7 May - 10 May found 11 hours ago Return direct flight included London (LON) to Panama City (PTY) 7.6/10 Good! (1,006 reviews) My room smelled like pee. Reviewed on 28 Feb 2026 ![Yoo by Wynwood House](https://images.trvl-media.com/lodging/104000000/103610000/103606300/103606257/93306cc0_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Yoo by Wynwood House Calidonia £2,209 per person 30 Apr - 4 May found 1 day ago Return direct flight included Birmingham (BHX) to Panama City (PTY) 9.2/10 Wonderful! (5 reviews) Unfortunately the name of the property was not Yoo by Wynwood. It is P. H. Yoo Panama & Arts Tower. This detail that was incorrect cost us time, money and stress at the beginning of our trip. We weren't able to get in touch with anyone at the property or at expedia and we ended up having to cross reference google photos to figure out the correct name and address of the location. This took us about an hour to do in a Country that we had never been to. We are very displeased with Expedia about this. We still have not been contacted by anyone. Reviewed on 26 Jul 2025 ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-uk-fr-de.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Holiday Sale Members save up to 40% on hotels and holiday homes. Plan this year’s big trip and save. [Book now](https://expedia.co.uk/cheap-deals?rfrr=PKG_SPRING_PROMO_6053183) ## Isla Grande Essential Information | Language | Spanish | | --------------- | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ | | Currency | Panamanian balboas | | Local Welcome | ¡Hola! | | Local Goodbye | Adiós | | Max Temp Winter | 27ºC | | Max Temp Summer | 29ºC | | Top Sights | [Blanca Beach](https://www.expedia.co.uk/Blanca-Beach-Portobelo.d6286205.Attraction), [Portobelo National Park](https://www.expedia.co.uk/Portobelo-National-Park-Colon.d6252836.Attraction) and [Mirador Perú](https://www.expedia.co.uk/Mirador-Peru-Portobelo.d553248621532964859.Attraction) | ## Top hotels in Isla Grande ![Hotel Cocotal](https://images.trvl-media.com/lodging/117000000/116790000/116790000/116789972/c828cfe9_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Cocotal La Guaira Isla Grande Provincia de Colón Fully refundableReserve now, pay when you stay £85 8 Mar - 9 Mar includes taxes & fees [](https://expedia.co.uk/Hotel-Search?startDate=08%2F03%2F2026&endDate=09%2F03%2F2026&selected=116789972&PinnedHotelID=116789972&HadPinnedHotel=true®ionId=6053183) ![HOTEL ISLA GRANDE ](https://images.trvl-media.com/lodging/120000000/119950000/119947200/119947185/9e6abf31_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### HOTEL ISLA GRANDE Final de paseo La Punta Isla Grande, 01 Isla Grande Colón Province 4.6/10 (7 reviews) This hotel is very run down, and should not be $150/night. Did not have access to running water in our room. Location and beach are its saving graces. Reviewed on 4 Feb 2026 [Get rates](https://expedia.co.uk/Hotel-Search?startDate=21%2F03%2F2026&endDate=22%2F03%2F2026&selected=119947185&PinnedHotelID=119947185&HadPinnedHotel=true®ionId=6053183) [](https://expedia.co.uk/Hotel-Search?startDate=21%2F03%2F2026&endDate=22%2F03%2F2026&selected=119947185&PinnedHotelID=119947185&HadPinnedHotel=true®ionId=6053183) ![Ordovician Beach Resort](https://images.trvl-media.com/lodging/104000000/103770000/103761600/103761591/9a39b281_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Ordovician Beach Resort Isla Grande Isla Grande Colon £411 8 Mar - 9 Mar includes taxes & fees 10/10 Exceptional! (9 reviews) The resort was outstanding. It exceeded expectations in every way. The service was the best we had in Panama. The cocktails were fun and the food was delicious and they have a vegan menu. We stayed in a king room and it was very private, pristine and well appointed. Reviewed on 21 Feb 2026 [](https://expedia.co.uk/Hotel-Search?startDate=08%2F03%2F2026&endDate=09%2F03%2F2026&selected=103761591&PinnedHotelID=103761591&HadPinnedHotel=true®ionId=6053183) [See all 54 properties in Isla Grande](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=08%2F03%2F2026&endDate=09%2F03%2F2026®ionId=6053183) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Holidays [](https://expedia.co.uk/lp/theme-holidays/all-inclusive-holidays?rfrr=editorial.All_Inclusive%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Holidays [](https://expedia.co.uk/lp/theme-holidays/beach-holidays?rfrr=editorial.Beach_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Friendly Holidays [](https://expedia.co.uk/lp/theme-holidays/kid-friendly-holidays?rfrr=editorial.Family_Friendly%20Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Holidays [](https://expedia.co.uk/lp/theme-holidays/golf-holidays?rfrr=editorial.Golf_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Holidays [](https://expedia.co.uk/lp/theme-holidays/luxury-holidays?rfrr=editorial.Luxury_Holidays.click) ![gay friendly holidays](https://forever.travel-assets.com/flex/flexmanager/images/2023/06/15/LGBTQIA_Holiday_Package.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) LGBTQ+ Holidays [](https://expedia.co.uk/lp/theme-holidays/gay-friendly-holidays?rfrr=editorial.LGBTQ+_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Holidays [](https://expedia.co.uk/lp/theme-holidays/romantic-holidays?rfrr=editorial.Romantic_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Holidays [](https://expedia.co.uk/lp/theme-holidays/ski-holidays?rfrr=editorial.Ski_Holidays.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/22/hero-image-pet-friendly_copy.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Pet Friendly Holidays [](https://expedia.co.uk/lp/theme-holidays/pet-friendly-holidays?rfrr=editorial.Pet_Friendly%20Holidays.click) ![Holiday in Month](https://forever.travel-assets.com/flex/flexmanager/images/2023/05/10/mesog-34434-card-venice.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Where to go when [](https://expedia.co.uk/lp/b/where-to-go-when?rfrr=editorial.Where_to%20go%20when.click) ## Explore a world of travel with Expedia \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app