
Isla Grande Holidays from £1,025
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to £750 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPackages with flights are ATOL protected
Your Isla Grande Holiday
With a Isla Grande holiday package, say goodbye to endless planning and hello to stress-free adventure. Every detail of your getaway has been taken care of before you go, so you can enjoy each moment discovering this lively city. If taking in the sights is a priority during your trip to Isla Grande, be sure to swing by famous attractions like Isla Mamey and Portobelo National Park. Whoever you're heading away with and whatever you want to spend, your dream Isla Grande holiday is just a few clicks away with Expedia.
Top Isla Grande Flight + Hotel Deals

Riande Aeropuerto Hotel & Casino
Reviewed on 11 Nov 2026


Hotel Riu Plaza Panama
Reviewed on 11 Nov 2026

Isla Grande Essential Information
Language | Spanish |
|---|---|
Currency | Panamanian balboas |
Local Welcome | ¡Hola! |
Local Goodbye | Adiós |
Max Temp Winter | 27ºC |
Max Temp Summer | 29ºC |
Top Sights | Blanca Beach, Portobelo National Park and Mirador Perú |
Top hotels in Isla Grande

Ordovician Beach Resort
"The best place in the world to have a relax and amazing vacation."
Reviewed on 5 Nov 2026

HOTEL ISLA GRANDE
"Rundown hotel. Not worth the price"
Reviewed on 31 Aug 2026

Hotel Cocotal
"Ocean view! Peaceful and the staff was SUPER attentive and friendly."
Reviewed on 24 Jun 2026
What to do in Isla Grande

Caribbean Catamaran Escape: Beaches, Snorkeling & Lunch

Snorkeling and Kayak Adventures in Portobelo beach
Frequently asked questions
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.












