Title: The Best Hotels Closest to Houston Natural Science Museum in Houston - 2026 Updated Prices | Expedia.co.uk [Houston Natural Science Museum Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Houston-Natural-Science-Museum.d501256.Car-Hire-Guide)[Houston Natural Science Museum Holidays](https://expedia.co.uk/Houston-Natural-Science-Museum-South-Central-Houston.d501256.Attraction) ![](https://images.trvl-media.com/place/501256/4e455af8-0f6d-48a6-81ba-874182e2abef.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/501256/4e455af8-0f6d-48a6-81ba-874182e2abef.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [26 Mar - 27 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=501256&startDate=2026-03-26&endDate=2026-03-27&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [27 Mar - 28 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=501256&startDate=2026-03-27&endDate=2026-03-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [27 Mar - 29 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=501256&startDate=2026-03-27&endDate=2026-03-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [3 Apr - 5 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=501256&startDate=2026-04-03&endDate=2026-04-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Property class ## Our top choices for Houston Natural Science Museum hotels ![Breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/107000000/106050000/106044500/106044495/91b8e94c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/107000000/106050000/106044500/106044495/7e1570e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily full breakfast for a fee](https://images.trvl-media.com/lodging/107000000/106050000/106044500/106044495/4077fd60.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 7:00 AM to 7:00 PM, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/107000000/106050000/106044500/106044495/ef05659d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Saint Augustine [](https://www.expedia.co.uk/Houston-Hotels-Hotel-Saint-Augustine.h106044495.Hotel-Information) Montrose, 1.1 mi from Houston Natural Science Museum 9.8/10 Exceptional (107 reviews) "Great hotel in a great location. Super friendly staff and great food at the hotel restaurant. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Antonios £208 includes taxes & fees 26 Apr - 27 Apr [](https://www.expedia.co.uk/Houston-Hotels-Hotel-Saint-Augustine.h106044495.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/21000000/20060000/20052300/20052267/dd39b10f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Texas Tower Suite | Premium bedding, down duvets, pillow-top beds, in-room safe](https://images.trvl-media.com/lodging/21000000/20060000/20052300/20052267/46db5ee8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/21000000/20060000/20052300/20052267/25489b27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/21000000/20060000/20052300/20052267/30a83dde.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only [](https://www.expedia.co.uk/Houston-Hotels-Houston-Towers-Inn-Downtown-Museum-District-Med-Ctr-NRG-Adults-Only.h20052267.Hotel-Information) 0.9 mi from Houston Natural Science Museum 9.6/10 Exceptional (207 reviews) "Every was excellent " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dolly £192 includes taxes & fees 30 Mar - 31 Mar [](https://www.expedia.co.uk/Houston-Hotels-Houston-Towers-Inn-Downtown-Museum-District-Med-Ctr-NRG-Adults-Only.h20052267.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/125000000/124550000/124544600/124544563/3a79aa60.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Suite | Property grounds](https://images.trvl-media.com/lodging/125000000/124550000/124544600/124544563/a9a9d12a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Suite | Living area](https://images.trvl-media.com/lodging/125000000/124550000/124544600/124544563/w2030h1450x0y0-5706ab85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/125000000/124550000/124544600/124544563/e0eb68fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Marlene Inn [](https://www.expedia.co.uk/Houston-Hotels-The-Marlene-Acquisition.h124544563.Hotel-Information) Montrose, 1.8 mi from Houston Natural Science Museum 10/10 Exceptional (8 reviews) "What lovely place to stay! We look forward to visiting again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marti £254 includes taxes & fees 29 Mar - 30 Mar [](https://www.expedia.co.uk/Houston-Hotels-The-Marlene-Acquisition.h124544563.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/13000000/12030000/12021700/12021677/f1f7afb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, Private Bathroom (Room 203B) | Living area | 32-inch flat-screen TV with cable channels, TV, DVD player](https://images.trvl-media.com/lodging/13000000/12030000/12021700/12021677/1b3590bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast ](https://images.trvl-media.com/lodging/13000000/12030000/12021700/12021677/83079f94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, Private Bathroom (Room 203B) | Premium bedding, individually decorated, individually furnished, desk](https://images.trvl-media.com/lodging/13000000/12030000/12021700/12021677/0db0a66e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Maison in Midtown an urban B&B [](https://www.expedia.co.uk/Houston-Hotels-La-Maison-In-Midtown-An-Urban-Bed-And-Breakfast.h12021677.Hotel-Information) Midtown, 1.8 mi from Houston Natural Science Museum 9.8/10 Exceptional (563 reviews) "Loved the area, the staff was super friendly and accomodating. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Silvia Alejandra £138 includes taxes & fees 16 Apr - 17 Apr [](https://www.expedia.co.uk/Houston-Hotels-La-Maison-In-Midtown-An-Urban-Bed-And-Breakfast.h12021677.Hotel-Information) ![Premium bedding, pillow-top beds, minibar, in-room safe](https://images.trvl-media.com/lodging/1000000/10000/3400/3306/0f950f88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillow-top beds, minibar, in-room safe](https://images.trvl-media.com/lodging/1000000/10000/3400/3306/8df6fdc6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/10000/3400/3306/5a45a026.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillow-top beds, minibar, in-room safe](https://images.trvl-media.com/lodging/1000000/10000/3400/3306/53ee2707.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Zaza Houston Museum District [](https://www.expedia.co.uk/Houston-Hotels-Hotel-Zaza-Houston-Museum-District.h3306.Hotel-Information) 0.2 mi from Houston Natural Science Museum 9.0/10 Wonderful (1,927 reviews) "Great vibe" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jennifer £232 includes taxes & fees 2 Apr - 3 Apr [](https://www.expedia.co.uk/Houston-Hotels-Hotel-Zaza-Houston-Museum-District.h3306.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/67000000/66880000/66878300/66878231/6b1ceada.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Snack bar](https://images.trvl-media.com/lodging/67000000/66880000/66878300/66878231/fdf1c598.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/67000000/66880000/66878300/66878231/74da78ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/67000000/66880000/66878300/66878231/ed3b731d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Home2 Suites by Hilton Houston Medical Center, TX [](https://www.expedia.co.uk/Houston-Hotels-Home2-Suites-By-Hilton-Houston-Medical-Center.h66878231.Hotel-Information) Texas Medical Center, 1.2 mi from Houston Natural Science Museum 9.4/10 Exceptional (622 reviews) "Adequate business facility. Great amenities. Great breakfast. Spacious rooms for the family. Friendly staff. Great shuttle service to the Houston Rodeo. Great free parking. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joseph £107 includes taxes & fees 5 Apr - 6 Apr [](https://www.expedia.co.uk/Houston-Hotels-Home2-Suites-By-Hilton-Houston-Medical-Center.h66878231.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/67000000/66430000/66425800/66425729/46e04cf8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily cooked-to-order breakfast (USD 14.95 per person)](https://images.trvl-media.com/lodging/67000000/66430000/66425800/66425729/a7fe5ff0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/67000000/66430000/66425800/66425729/c4f24f6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/67000000/66430000/66425800/66425729/8293c765.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden Inn Houston Medical Center, TX [](https://www.expedia.co.uk/Houston-Hotels-Hilton-Garden-Inn-Houston-Medical-Center.h66425729.Hotel-Information) Texas Medical Center, 1.2 mi from Houston Natural Science Museum 9.2/10 Wonderful (1,000 reviews) "We have stayed here for Medical appointments in Houston... can not say enough about this hotel's and its support staff... " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joan £94 includes taxes & fees 5 Apr - 6 Apr [](https://www.expedia.co.uk/Houston-Hotels-Hilton-Garden-Inn-Houston-Medical-Center.h66425729.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/67000000/66960000/66954200/66954154/faff2120.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Serves breakfast, lunch and dinner](https://images.trvl-media.com/lodging/67000000/66960000/66954200/66954154/805d0af4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/67000000/66960000/66954200/66954154/2fc8cb04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Billiards](https://images.trvl-media.com/lodging/67000000/66960000/66954200/66954154/w5792h8683x0y0-ac43f8f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Colombe d'Or Hotel [](https://www.expedia.co.uk/Houston-Hotels-La-Colombe-DOr-Hotel.h66954154.Hotel-Information) Montrose, 1.4 mi from Houston Natural Science Museum 9.4/10 Exceptional (176 reviews) "Absolutely lovely place, and I'd highly recommend it!" ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Paul £329 includes taxes & fees 9 Apr - 10 Apr [](https://www.expedia.co.uk/Houston-Hotels-La-Colombe-DOr-Hotel.h66954154.Hotel-Information) ![Outdoor pool, free pool cabanas, pool umbrellas](https://images.trvl-media.com/lodging/40000000/39620000/39618700/39618635/a994a387.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/40000000/39620000/39618700/39618635/w3998h2667x2y0-ff5ca8a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/40000000/39620000/39618700/39618635/c202dd0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/40000000/39620000/39618700/39618635/9235e98a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Westin Houston Medical Center/Museum District [](https://www.expedia.co.uk/Houston-Hotels-The-Westin-Houston-Medical-Center.h39618635.Hotel-Information) Texas Medical Center, 1.1 mi from Houston Natural Science Museum 9.2/10 Wonderful (1,129 reviews) "Great central location within the walking distance to many places. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kasey £165 includes taxes & fees 29 Mar - 30 Mar [](https://www.expedia.co.uk/Houston-Hotels-The-Westin-Houston-Medical-Center.h39618635.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/24000000/23840000/23830900/23830866/2ea79db9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/24000000/23840000/23830900/23830866/d4fcf53e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/24000000/23840000/23830900/23830866/b5377510.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, individually furnished, desk](https://images.trvl-media.com/lodging/24000000/23840000/23830900/23830866/5f5e8d93.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### InterContinental Houston by IHG [](https://www.expedia.co.uk/Houston-Hotels-InterContinental-Houston-Medical-Center.h23830866.Hotel-Information) Texas Medical Center, 1.4 mi from Houston Natural Science Museum 9.2/10 Wonderful (1,003 reviews) "Amazing hotel. Beautiful property, wonderful customer service." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) LATOYA £161 includes taxes & fees 29 Mar - 30 Mar [](https://www.expedia.co.uk/Houston-Hotels-InterContinental-Houston-Medical-Center.h23830866.Hotel-Information) ![American cuisine](https://images.trvl-media.com/lodging/1000000/20000/16200/16154/647bab8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, down duvets, pillow-top beds](https://images.trvl-media.com/lodging/1000000/20000/16200/16154/87753400.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Mini-fridge, coffee/tea maker](https://images.trvl-media.com/lodging/1000000/20000/16200/16154/c3718846.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/16200/16154/d72506d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Houston Marriott Medical Center/Museum District [](https://www.expedia.co.uk/Houston-Hotels-Houston-Marriott-Medical-CenterMuseum-District.h16154.Hotel-Information) Texas Medical Center, 1.1 mi from Houston Natural Science Museum 9.0/10 Wonderful (1,000 reviews) "Everything was great " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Casey £181 includes taxes & fees 3 Apr - 4 Apr [](https://www.expedia.co.uk/Houston-Hotels-Houston-Marriott-Medical-CenterMuseum-District.h16154.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/89000000/88140000/88130500/88130440/a6f86b3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/89000000/88140000/88130500/88130440/eec7b544.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/89000000/88140000/88130500/88130440/6748ac8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/89000000/88140000/88130500/88130440/71ab7d99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Place Houston Medical Center [](https://www.expedia.co.uk/Houston-Hotels-Hyatt-Place-Houston-Medical-Center.h88130440.Hotel-Information) Texas Medical Center, 1.9 mi from Houston Natural Science Museum 9.2/10 Wonderful (2,431 reviews) "We enjoyed our stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dunya £111 includes taxes & fees 5 Apr - 6 Apr [](https://www.expedia.co.uk/Houston-Hotels-Hyatt-Place-Houston-Medical-Center.h88130440.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/84000000/83760000/83751000/83750993/31c2b88f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/84000000/83760000/83751000/83750993/1d77a540.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/84000000/83760000/83751000/83750993/f81e2b4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Panoramic Suite, 1 King Bed (1 Bedroom) | Premium bedding, in-room safe, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/84000000/83760000/83751000/83750993/w6142h3840x5y0-1df7f040.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt House Houston Medical Center [](https://www.expedia.co.uk/Houston-Hotels-Hyatt-House-Houston-Medical-Center.h83750993.Hotel-Information) Texas Medical Center, 1.9 mi from Houston Natural Science Museum 9.2/10 Wonderful (1,254 reviews) "Enjoyed our stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sharonda £112 includes taxes & fees 5 Apr - 6 Apr [](https://www.expedia.co.uk/Houston-Hotels-Hyatt-House-Houston-Medical-Center.h83750993.Hotel-Information) ![Fridge, microwave, stovetop, cookware/dishes/utensils](https://images.trvl-media.com/lodging/33000000/32740000/32732700/32732673/09556c16.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Room, Multiple Beds | In-room safe, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/33000000/32740000/32732700/32732673/66bb1c86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/33000000/32740000/32732700/32732673/64fbc0f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily cooked-to-order breakfast ](https://images.trvl-media.com/lodging/33000000/32740000/32732700/32732673/135bf85f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Modern B & B [](https://www.expedia.co.uk/Houston-Hotels-Modern-B-B.h32732673.Hotel-Information) Montrose, 1.4 mi from Houston Natural Science Museum 9.0/10 Wonderful (221 reviews) "Place was clean and staff was friendly. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Peyton £98 includes taxes & fees 29 Mar - 30 Mar [](https://www.expedia.co.uk/Houston-Hotels-Modern-B-B.h32732673.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/59000000/58990000/58985900/58985846/w3837h2505x3y0-1cfabad9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/59000000/58990000/58985900/58985846/w3837h2768x3y3-aed6fd99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, minibar, in-room safe, individually decorated](https://images.trvl-media.com/lodging/59000000/58990000/58985900/58985846/1d5101c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/59000000/58990000/58985900/58985846/w3837h2340x3y0-41c8f6ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Blossom Hotel Houston, Curio Collection by Hilton [](https://www.expedia.co.uk/Houston-Hotels-Blossom-Hotel-Houston.h58985846.Hotel-Information) Texas Medical Center, 1.7 mi from Houston Natural Science Museum 9.0/10 Wonderful (3,731 reviews) "Beautiful hotel in a great location." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lesley and Sam £150 includes taxes & fees 26 Apr - 27 Apr [](https://www.expedia.co.uk/Houston-Hotels-Blossom-Hotel-Houston.h58985846.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/77443f8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, rooftop bar](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/280705eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/e15c188d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/8964faa3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Houston Plaza/Medical Center [](https://www.expedia.co.uk/Houston-Hotels-Hilton-Houston-Plaza-Medical-Center.h25188.Hotel-Information) Texas Medical Center, 1.2 mi from Houston Natural Science Museum 8.4/10 Very good (1,865 reviews) "Very clean property, staff was helpful" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Elton £74 includes taxes & fees 5 Apr - 6 Apr [](https://www.expedia.co.uk/Houston-Hotels-Hilton-Houston-Plaza-Medical-Center.h25188.Hotel-Information) ![Breakfast and dinner served](https://images.trvl-media.com/lodging/1000000/10000/6700/6636/w3830h2557x6y0-b53d88b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/10000/6700/6636/451a0d3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/10000/6700/6636/856ff5b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/6700/6636/1c784498.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### DoubleTree by Hilton Houston Medical Center Hotel & Suites [](https://www.expedia.co.uk/Houston-Hotels-Wyndham-Houston-Medical-Center-Hotel-And-Suites.h6636.Hotel-Information) Texas Medical Center, 1.4 mi from Houston Natural Science Museum 8.4/10 Very good (546 reviews) "Breakfast was pricey" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Thomas £93 includes taxes & fees 26 Apr - 27 Apr [](https://www.expedia.co.uk/Houston-Hotels-Wyndham-Houston-Medical-Center-Hotel-And-Suites.h6636.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/70000/67700/67691/11fb683b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/70000/67700/67691/eb893beb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![27-inch TV with cable channels, DVD player](https://images.trvl-media.com/lodging/1000000/70000/67700/67691/a7f613a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![King Studio w/ Sofa Bed | Living area | 27-inch TV with cable channels, DVD player](https://images.trvl-media.com/lodging/1000000/70000/67700/67691/6a9130bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Houston Medical Center NRG Park [](https://www.expedia.co.uk/Houston-Hotels-Hampton-Inn-Suites-Houston-Medical-Center-NRG-Park.h67691.Hotel-Information) Texas Medical Center, 2 mi from Houston Natural Science Museum 8.4/10 Very good (1,000 reviews) "Great place, amenities and awesome staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mel £87 includes taxes & fees 5 Apr - 6 Apr [](https://www.expedia.co.uk/Houston-Hotels-Hampton-Inn-Suites-Houston-Medical-Center-NRG-Park.h67691.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/5000000/4110000/4100300/4100218/d27297d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/bathtub, free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/5000000/4110000/4100300/4100218/eabe2e20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi, bed sheets, alarm clocks](https://images.trvl-media.com/lodging/5000000/4110000/4100300/4100218/0e5ea9f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/5000000/4110000/4100300/4100218/8b5aa8e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Americas Best Value Inn Medical Center Downtown [](https://www.expedia.co.uk/Houston-Hotels-Americas-Best-Value-Inn-Medical-Center-Downtown.h4100218.Hotel-Information) 0.8 mi from Houston Natural Science Museum 8.0/10 Very good (1,000 reviews) "Very clean room, staff was very good, felt safe" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gayle £86 includes taxes & fees 4 Apr - 5 Apr [](https://www.expedia.co.uk/Houston-Hotels-Americas-Best-Value-Inn-Medical-Center-Downtown.h4100218.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/118000000/117470000/117463300/117463205/354e5ecd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/118000000/117470000/117463300/117463205/e139024d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/118000000/117470000/117463300/117463205/59d648f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed | Laptop workspace, blackout curtains, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/118000000/117470000/117463300/117463205/593d463b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Downtowner Inns - Houston Downtown [](https://www.expedia.co.uk/Houston-Hotels-Downtowner-Inns-Houston-Downtown.h117463205.Hotel-Information) Midtown, 1.9 mi from Houston Natural Science Museum 8.4/10 Very good (88 reviews) "Good hotel. great location. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Porfirio £75 includes taxes & fees 2 Apr - 3 Apr [](https://www.expedia.co.uk/Houston-Hotels-Downtowner-Inns-Houston-Downtown.h117463205.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-04-09&endDate=2026-04-10®ionId=501256&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Compare popular hotels close to Houston Natural Science Museum | Property | Property class | Guest rating | Breakfast included | Pool | Spa | Pet-friendly | WiFi included | | | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | ----------------- | ------------------------- | ------------------ | ---- | --- | ------------ | ------------- | | | ![Breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/107000000/106050000/106044500/106044495/91b8e94c.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Hotel Saint Augustine | 3.5 star property | 9.8Exceptional107 reviews | View | | | | | | | ![Outdoor pool](https://images.trvl-media.com/lodging/21000000/20060000/20052300/20052267/dd39b10f.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only | 3.5 star property | 9.6Exceptional207 reviews | View | | | | | | | ![Exterior](https://images.trvl-media.com/lodging/125000000/124550000/124544600/124544563/3a79aa60.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)The Marlene Inn | 4.0 star property | 10.0Exceptional8 reviews | View | | | | | | | ![Exterior](https://images.trvl-media.com/lodging/13000000/12030000/12021700/12021677/f1f7afb4.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)La Maison in Midtown an urban B&B | 3.5 star property | 9.8Exceptional563 reviews | View | | | | | | | ![Premium bedding, pillow-top beds, minibar, in-room safe](https://images.trvl-media.com/lodging/1000000/10000/3400/3306/0f950f88.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Hotel Zaza Houston Museum District | 4.5 star property | 9.0Wonderful1,927 reviews | View | | | | | | ## Top Houston Natural Science Museum Hotel Reviews ![Americas Best Value Inn Medical Center Downtown](https://images.trvl-media.com/lodging/5000000/4110000/4100300/4100218/d27297d7_y.jpg) ### Americas Best Value Inn Medical Center Downtown 10/10 Excellent "Clean, convenient, quiet and very friendly staff. Would stay here again." [](https://expedia.co.uk/Houston-Hotels-Americas-Best-Value-Inn-Medical-Center-Downtown.h4100218.Hotel-Information) ![La Colombe d'Or Hotel](https://images.trvl-media.com/lodging/67000000/66960000/66954200/66954154/faff2120_y.jpg) ### La Colombe d'Or Hotel 10/10 Excellent "I didn’t realize it was such a big property and traveling by myself with a heavy suitcase, I should’ve requested to be in the towers for ease. I stayed in the bungalows and it seemed far away, but it was incredibly beautiful and a fabulous bungalow! Jenny at the front desk truly was above and beyond in making me welcome comfortable and getting to know the property more. " [](https://expedia.co.uk/Houston-Hotels-La-Colombe-DOr-Hotel.h66954154.Hotel-Information) ![InterContinental Houston by IHG](https://images.trvl-media.com/lodging/24000000/23840000/23830900/23830866/2ea79db9_y.jpg) ### InterContinental Houston by IHG 10/10 Excellent "Friendly staff, well maintained " [](https://expedia.co.uk/Houston-Hotels-InterContinental-Houston-Medical-Center.h23830866.Hotel-Information) ![Wanderstay Houston Hostel](https://images.trvl-media.com/lodging/31000000/30450000/30445900/30445852/26035abc_y.jpg) ### Wanderstay Houston Hostel 10/10 Excellent "it was a great experience, staff was kind and helpful. " [](https://expedia.co.uk/Houston-Hotels-Wanderstay-Houston-Hostel.h30445852.Hotel-Information) ![Blossom Hotel Houston, Curio Collection by Hilton](https://images.trvl-media.com/lodging/59000000/58990000/58985900/58985846/w3837h2505x3y0-1cfabad9_y.jpg) ### Blossom Hotel Houston, Curio Collection by Hilton 8/10 Good "The room was clean. The hotel has great staff. Valet is efficient. There is not much food or drink available so be prepared. " [](https://expedia.co.uk/Houston-Hotels-Blossom-Hotel-Houston.h58985846.Hotel-Information) ![Hilton Garden Inn Houston Medical Center, TX](https://images.trvl-media.com/lodging/67000000/66430000/66425800/66425729/46e04cf8_y.jpg) ### Hilton Garden Inn Houston Medical Center, TX 10/10 Excellent "We have stayed here for Medical appointments in Houston... can not say enough about this hotel's and its support staff... " [](https://expedia.co.uk/Houston-Hotels-Hilton-Garden-Inn-Houston-Medical-Center.h66425729.Hotel-Information) ![Hilton Houston Plaza/Medical Center](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/77443f8e_y.jpg) ### Hilton Houston Plaza/Medical Center 4/10 Poor "Extremely noisy. Starting around 6:00AM there was constant noise. Carts rolling, walkie talkies , loud talking in the halls. Did not get a good night's sleep." [](https://expedia.co.uk/Houston-Hotels-Hilton-Houston-Plaza-Medical-Center.h25188.Hotel-Information) ![Hotel Zaza Houston Museum District](https://images.trvl-media.com/lodging/1000000/10000/3400/3306/0f950f88_y.jpg) ### Hotel Zaza Houston Museum District 10/10 Excellent "Great vibe" [](https://expedia.co.uk/Houston-Hotels-Hotel-Zaza-Houston-Museum-District.h3306.Hotel-Information) ![Lodgeur Midtown](https://images.trvl-media.com/lodging/46000000/45750000/45746100/45746041/ddf71f43_y.jpg) ### Lodgeur Midtown 10/10 Excellent "Detailed check instructions and leasing office was helpful, can’t beat free parking in that area. " [](https://expedia.co.uk/Houston-Hotels-Lodgeur-At-Mid-Main-Lofts.h45746041.Hotel-Information) ## Hotels near other Houston Natural Science Museum attractions ![Museum of Fine Arts Houston - Kinder building architecture](https://images.trvl-media.com/place/501255/c1eeb80f-3448-4ffa-98a7-332c5214c1f6.jpg) ### Houston Museum of Fine Arts 4.7/5 (250 reviews) Architecturally stunning and filled with pieces by renowned artists of the world, this museum is a must-see for art lovers. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=501255) ![The most happening place for toddlers in houston](https://images.trvl-media.com/place/1503/96c11d98-39b2-41f9-b570-bdc68afb4888.jpg) Photo by Mariam Ahmed ### Children's Museum of Houston You can take time to visit Children's Museum of Houston during your travels to Houston. Experience the area's acclaimed art galleries and great live music. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6082211) ![A Houston mecca for modern art. The museum was founded in 1948 and presented art in locations all over the city. In 1972, CAMH moved into this beautiful facility designed by Gunnar Birkerts.](https://images.trvl-media.com/place/1503/c64aa0b3-f92b-4727-bd76-ff291e0a7753.jpg) Photo by W. Ross Wells ### Houston Contemporary Arts Museum You can spend time exploring the galleries in Houston Contemporary Arts Museum in Houston. Experience the area's acclaimed art galleries and fascinating museums. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=501252) ### Health Museum You can spend an afternoon studying the exhibits at Health Museum during your trip to Houston. Experience the area's acclaimed art galleries or attend a sporting event. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6082225) ### Miller Outdoor Theater You can make plans for a show at Miller Outdoor Theater on your trip to Houston. Experience the area's fascinating museums and acclaimed art galleries. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6082229) ### St. Paul's United Methodist Church After visiting St. Paul's United Methodist Church, make a plan to see the other sights and activities in Houston. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=799022423512330240) ### Holocaust Museum Houston You can spend an afternoon exploring the galleries in Holocaust Museum Houston in Houston. Experience the acclaimed theatre scene or attend a sporting event in this vibrant area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6082217) ### The Jung Center Enjoy the student vibe when you visit The Jung Center during your travels in Houston. Experience the acclaimed theatre scene or attend a sporting event in this vibrant area. [See properties](https://www.expedia.co.uk/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621532644493) ## Frequently asked questions ### What's the area like around Houston Natural Science Museum? ### What's the best place to stay near Houston Natural Science Museum? ### How many hotels should I expect to find near Houston Natural Science Museum? ### If I need to cancel the hotel reservation for my stay near Houston Natural Science Museum, will I receive a refund? ### What can I see and do near Houston Natural Science Museum? ### How can I get to Houston Natural Science Museum?