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11 Nov - 12 Nov
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12 Nov - 13 Nov
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13 Nov - 15 Nov
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20 Nov - 22 Nov

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Our top choices for Houston Natural Science Museum hotels

A stately building with a symmetrical facade, large windows, and a central entrance.

1. The Marlene Inn

The Marlene Inn
4.0 star property
Montrose, 1.8 mi from Houston Natural Science Museum
9.8 out of 10, Exceptional, (41 reviews)
"Loved everything about it, the bar was particularly amazing."
United States
Brenagh
The price is £274
includes taxes & fees
15 Nov - 16 Nov
The Marlene Inn
A large, multi-story house with a swimming pool, outdoor seating, and a red umbrella.

2. Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only

Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
3.5 star property
0.9 mi from Houston Natural Science Museum
9.6 out of 10, Exceptional, (221 reviews)
"The room was very clean, the staff was just great and the breakfast was very good! The Parking was a little difficult, but it was very safe!"
United States
Walter
The price is £137
includes taxes & fees
12 Nov - 13 Nov
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
A modern building with multiple floors, large windows, and outdoor seating area with chairs and tables.

3. Hotel Saint Augustine

Hotel Saint Augustine
3.5 star property
Montrose, 1.1 mi from Houston Natural Science Museum
9.6 out of 10, Exceptional, (190 reviews)
"Perfect stay from check-in to check-out. Would absolutely stay here again!"
United States
Jacqueline
The price is £258
includes taxes & fees
29 Nov - 30 Nov
Hotel Saint Augustine
A modern hotel building with a prominent entrance, large windows, and a visible name sign.

4. InterContinental Houston by IHG

InterContinental Houston by IHG
4.0 star property
Texas Medical Center, 1.4 mi from Houston Natural Science Museum
9.4 out of 10, Exceptional, (1,007 reviews)
"Great stay!"
United States
Luke
The price is £147
includes taxes & fees
22 Nov - 23 Nov
InterContinental Houston by IHG
A modern hotel room with a large bed, a black leather sofa, a wooden coffee table, and a desk with a mirror.

5. Downtowner Inns - Houston Downtown

Downtowner Inns - Houston Downtown
2.0 star property
Midtown, 1.9 mi from Houston Natural Science Museum
9.2 out of 10, Wonderful, (280 reviews)
"Great place and close to downtown."
United States
Israel
The price is £80
includes taxes & fees
15 Nov - 16 Nov
Downtowner Inns - Houston Downtown
A rooftop pool area with lounge chairs and a view of a tall building at night.

6. The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District
4.0 star property
Texas Medical Center, 1.1 mi from Houston Natural Science Museum
9.2 out of 10, Wonderful, (1,286 reviews)
"Good hotel. Clean and nice staff."
United States
Ariane
The price is £110
includes taxes & fees
15 Nov - 16 Nov
The Westin Houston Medical Center/Museum District
A spacious living area with a dining table, chairs, and a chandelier.

7. Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District
4.5 star property
0.2 mi from Houston Natural Science Museum
9.2 out of 10, Wonderful, (1,014 reviews)
"Courteous staff, conveniently located. Very good amenities."
United States
David
The price is £203
includes taxes & fees
22 Nov - 23 Nov
Hotel Zaza Houston Museum District
An outdoor patio area with round wooden tables and wicker chairs, featuring a lantern and modern lighting fixtures.

8. Hilton Garden Inn Houston Medical Center, TX

Hilton Garden Inn Houston Medical Center, TX
3.0 star property
Texas Medical Center, 1.2 mi from Houston Natural Science Museum
9.2 out of 10, Wonderful, (1,008 reviews)
"Will stay again , highly recommend!"
United States
Shatara
The price is £92
includes taxes & fees
22 Nov - 23 Nov
Hilton Garden Inn Houston Medical Center, TX
A spacious hotel lobby with high ceilings, large windows, a long bar area, and a seating area with a sofa and chairs.

9. Hyatt Place Houston Medical Center

Hyatt Place Houston Medical Center
3.0 star property
Texas Medical Center, 1.9 mi from Houston Natural Science Museum
9.2 out of 10, Wonderful, (2,735 reviews)
"Great place to stay"
United States
Joel
The price is £109
includes taxes & fees
26 Nov - 27 Nov
Hyatt Place Houston Medical Center
A spacious hotel lobby with high ceilings, large windows, a long bar area, and a seating area with a sofa and chairs.

10. Hyatt House Houston Medical Center

Hyatt House Houston Medical Center
3.0 star property
Texas Medical Center, 1.9 mi from Houston Natural Science Museum
9.2 out of 10, Wonderful, (1,288 reviews)
"Clean rooms, helpful staff, and great breakfast."
United States
Nikki
The price is £109
includes taxes & fees
26 Nov - 27 Nov
Hyatt House Houston Medical Center
An outdoor patio area with round wooden tables and wicker chairs, featuring a lantern and modern lighting fixtures.

11. Home2 Suites by Hilton Houston Medical Center, TX

Home2 Suites by Hilton Houston Medical Center, TX
3.0 star property
Texas Medical Center, 1.2 mi from Houston Natural Science Museum
9.2 out of 10, Wonderful, (763 reviews)
"This room was spacious and had more amenities than a normal in a double queen room. We enjoyed our stay and will come here again!"
United States
Colleen
The price is £110
includes taxes & fees
22 Nov - 23 Nov
Home2 Suites by Hilton Houston Medical Center, TX
A high-rise hotel with a rooftop pool, multiple floors, and a cityscape view.

12. Sentral Forme Houston

Sentral Forme Houston
4.5 star property
0.3 mi from Houston Natural Science Museum
9.2 out of 10, Wonderful, (102 reviews)
"Enjoyable stay with all the comforts of home."
United States
ebony noelle
The price is £204
includes taxes & fees
23 Nov - 24 Nov
Sentral Forme Houston
A hotel lobby with a grand chandelier, a reception desk, and a carpet with the hotel's name.

13. Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton
4.0 star property
Texas Medical Center, 1.7 mi from Houston Natural Science Museum
9.0 out of 10, Wonderful, (3,825 reviews)
"Great hotel definitely would stay again."
United States
Michael
The price is £128
includes taxes & fees
22 Nov - 23 Nov
Blossom Hotel Houston, Curio Collection by Hilton
A modern restaurant with a bar area, featuring a patterned floor, multiple dining tables, and contemporary lighting fixtures.

14. Houston Marriott Medical Center/Museum District

Houston Marriott Medical Center/Museum District
4.0 star property
Texas Medical Center, 1.1 mi from Houston Natural Science Museum
9.0 out of 10, Wonderful, (1,000 reviews)
"Location was best"
United States
Nafisa
The price is £156
includes taxes & fees
22 Nov - 23 Nov
Houston Marriott Medical Center/Museum District
A modern kitchen with a central island, stainless steel bar stools, a black refrigerator, and white cabinetry.

15. Modern B & B

Modern B & B
3.5 star property
Montrose, 1.4 mi from Houston Natural Science Museum
9.0 out of 10, Wonderful, (254 reviews)
"Neighborhood was nice"
United States
LISA
The price is £69
includes taxes & fees
13 Nov - 14 Nov
Modern B & B
A rooftop patio with outdoor seating, fire pits, and a view of the cityscape.

16. Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center
4.5 star property
Texas Medical Center, 1.2 mi from Houston Natural Science Museum
8.6 out of 10, Excellent, (2,258 reviews)
"Very nice, would stay again!"
United States
Amanda
The price is £74
includes taxes & fees
23 Nov - 24 Nov
Hilton Houston Plaza/Medical Center
A spacious dining area with multiple tables and chairs, large windows, and hanging pendant lights.

17. DoubleTree by Hilton Houston Medical Center Hotel & Suites

DoubleTree by Hilton Houston Medical Center Hotel & Suites
4.0 star property
Texas Medical Center, 1.4 mi from Houston Natural Science Museum
8.4 out of 10, Very good, (722 reviews)
"Nice and convenient to the medical center"
United States
CHRISTY
The price is £99
includes taxes & fees
22 Nov - 23 Nov
DoubleTree by Hilton Houston Medical Center Hotel & Suites
A modern dining area with a long table and chairs, a chandelier, and a television on the wall.

18. Hampton Inn & Suites Houston Medical Center NRG Park

Hampton Inn & Suites Houston Medical Center NRG Park
2.5 star property
Texas Medical Center, 2 mi from Houston Natural Science Museum
8.4 out of 10, Very good, (1,013 reviews)
"Everyone was kind and helpful! Check in was easy and staff was accommodating when we need to stay an extra night for medical reasons. Hotel is super convenient to out medical appointments."
United States
Ana
The price is £96
includes taxes & fees
22 Nov - 23 Nov
Hampton Inn & Suites Houston Medical Center NRG Park
A modern reception area with a blackboard, a blue sofa, a yellow armchair, and a colorful rug.

19. Wanderstay Houston Hostel

Wanderstay Houston Hostel
2.0 star property
Museum District, 1.2 mi from Houston Natural Science Museum
8.2 out of 10, Very good, (220 reviews)
"Horrible do not stay here."
United States
Nathalia
The price is £42
includes taxes & fees
15 Nov - 16 Nov
Wanderstay Houston Hostel
A modern kitchen with dark wood cabinets, a granite countertop, and a built-in island with a glass enclosure.

20. Americas Best Value Inn Medical Center Downtown

Americas Best Value Inn Medical Center Downtown
2.0 star property
0.8 mi from Houston Natural Science Museum
8.0 out of 10, Very good, (1,001 reviews)
"Great Stay"
United States
Randy
The price is £76
includes taxes & fees
13 Nov - 14 Nov
Americas Best Value Inn Medical Center Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Compare popular hotels close to Houston Natural Science Museum

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A stately building with a symmetrical facade, large windows, and a central entrance.
The Marlene Inn
4.0 star property
9.8
Exceptional
41 reviews
View
A large, multi-story house with a swimming pool, outdoor seating, and a red umbrella.
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
3.5 star property
9.6
Exceptional
221 reviews
View
A modern building with multiple floors, large windows, and outdoor seating area with chairs and tables.
Hotel Saint Augustine
3.5 star property
9.6
Exceptional
190 reviews
View
A modern hotel building with a prominent entrance, large windows, and a visible name sign.
InterContinental Houston by IHG
4.0 star property
9.4
Exceptional
1,007 reviews
View
A modern hotel room with a large bed, a black leather sofa, a wooden coffee table, and a desk with a mirror.
Downtowner Inns - Houston Downtown
2.0 star property
9.2
Wonderful
280 reviews
View

Other attractions near Houston Natural Science Museum

An art gallery with wooden floors and walls, featuring several framed paintings.

Houston Museum of Fine Arts

9.4/10 (258 reviews)
Architecturally stunning and filled with pieces by renowned artists of the world, this museum is a must-see for art lovers.
See properties

Top Houston Natural Science Museum Hotel Reviews

A modern hotel building with a prominent entrance, large windows, and a visible name sign.
InterContinental Houston by IHG

InterContinental Houston by IHG

InterContinental Houston by IHG
Texas Medical Center

10/10 Excellent

Great clean property, pleasant atmosphere.
United Kingdom
James
Reviewed August 5, 2025
InterContinental Houston by IHG

Frequently Asked Questions

What's the area like around Houston Natural Science Museum?

Houston Natural Science Museum is located in an area of Houston known for its top museums and popular art scene. If you're looking for a convenient place to stay, take a look at the 209 hotels and other accommodation options you'll find within a mile.

What's the best place to stay near Houston Natural Science Museum?

Adjacent to Houston Natural Science Museum, Hotel Zaza Houston Museum District is one of the top choices for your stay based on our traveller data, and this hotel offers a full-service spa and a restaurant. Other good options within a short distance include Sentral Forme Houston and Americas Best Value Inn Medical Center Downtown.

How many hotels should I expect to find near Houston Natural Science Museum?

Expedia has 209 hotels and other accommodation options within a mile from Houston Natural Science Museum.

If I need to cancel the hotel reservation for my stay near Houston Natural Science Museum, will I receive a refund?

Yes! Most hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, it may still be possible to cancel it and get a refund within a 24-hour period of booking. Add dates, click "Search", then use the filter option "fully refundable" to get the best deals available near Houston Natural Science Museum.

What can I see and do near Houston Natural Science Museum?

You might want to spend some time browsing the exhibits at Houston Museum of Fine Arts, Menil Collection or Health Museum. Sights like Reliant Park, Eldorado Ballroom and Freedmenstown are must-sees while exploring the area. You can catch a show at Main Street Theater - Rice Village, House of Blues Houston and Jesse H. Jones Hall.

How can I get to Houston Natural Science Museum?

With so many transport options, seeing the area around Houston Natural Science Museum is easy. Walk to nearby metro stations like Palm Center Transit Center, MacGregor Park/Martin Luther King Jr. Station and UH South/University Oaks Station. To explore the surrounding area, ride one of the trains from Kinder Station or M. D. Anderson Station.