Title: TOP Adults Only Resorts & Hotels in Greenville, NC for 2026 | Expedia.co.uk [Hotels in Greenville](https://expedia.co.uk/Greenville-Hotels.d2779.Travel-Guide-Hotels)[Holiday Rentals in Greenville](https://expedia.co.uk/Greenville-Holiday-Rentals.d2779.Travel-Guide-HolidayRentals)[Flights to Greenville](https://expedia.co.uk/Cheap-Flights-To-Greenville.d2779.Travel-Guide-Flights)[Greenville Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Greenville.d2779.Car-Hire-Guide)[Greenville Holidays](https://expedia.co.uk/Greenville.d2779.Holidays-City-Breaks) ![](https://images.trvl-media.com/place/2779/2cc4f2b6-8827-4d1a-a6b8-67c248044796.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Adults Only Resorts & Hotels in Greenville - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Greenville Adults Only Resorts & Hotels Tonight [7 Dec - 8 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=2779&startDate=2025-12-07&endDate=2025-12-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) Tomorrow [8 Dec - 9 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=2779&startDate=2025-12-08&endDate=2025-12-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) Next weekend [12 Dec - 14 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=2779&startDate=2025-12-12&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) In two weeks [19 Dec - 21 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=2779&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=adults_only) ## Top Greenville Adults Only Resorts & Hotels No exact matches found, but these alternatives could be just right ## Recommended hotels in Greenville ![Exterior](https://images.trvl-media.com/lodging/109000000/108400000/108395100/108395066/w3837h2557x3y3-9ca87b37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/109000000/108400000/108395100/108395066/w3837h2415x3y3-72322295.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/109000000/108400000/108395100/108395066/w3837h2560x3y0-dfdc5921.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/109000000/108400000/108395100/108395066/w3840h2557x0y3-6eee03ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Garden INN Greenville University Uptown Greenville 9.4/10 Exceptional (91) "Great location. Rooftop bar and restaurant was nice and convenient." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) GEORGE £101 includes taxes & fees 21 Dec - 22 Dec [](https://www.expedia.co.uk/Greenville-Hotels-Hilton-Garden-INN-Greenville-University.h108395066.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/105000000/104470000/104466400/104466390/356f6fc4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/105000000/104470000/104466400/104466390/fdf12260.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/105000000/104470000/104466400/104466390/1ffe3d21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi](https://images.trvl-media.com/lodging/105000000/104470000/104466400/104466390/ce0cefde.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Staybridge Suites Greenville Medical Center by IHG Greenville 9.4/10 Exceptional (228) "Great hotel!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mario £85 includes taxes & fees 21 Dec - 22 Dec [](https://www.expedia.co.uk/Greenville-Hotels-Staybridge-Suites-Greenville-Medical-Center.h104466390.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/91000000/90160000/90153300/90153266/36cd8e9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/91000000/90160000/90153300/90153266/90561384.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee/tea maker](https://images.trvl-media.com/lodging/91000000/90160000/90153300/90153266/12a39e10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![42-inch Smart TV with cable channels, TV](https://images.trvl-media.com/lodging/91000000/90160000/90153300/90153266/4540394d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Homewood Suites By Hilton Greenville, NC Greenville 9.4/10 Exceptional (303) "Room was perfect. We really appreciate our stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carol £101 includes taxes & fees 15 Dec - 16 Dec [](https://www.expedia.co.uk/Greenville-Hotels-Homewood-Suites-By-Hilton-Greenville.h90153266.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/3000000/2600000/2593900/2593867/31fb46e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/3000000/2600000/2593900/2593867/56c242c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2600000/2593900/2593867/2da51b79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2600000/2593900/2593867/fa35fdb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Greenville Greenville 9.0/10 Wonderful (567) "Great stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mario £87 includes taxes & fees 21 Dec - 22 Dec [](https://www.expedia.co.uk/Greenville-Hotels-Hampton-Inn-Greenville.h2593867.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/300000/296600/296584/60480ad3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/300000/296600/296584/2bf50710.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/300000/296600/296584/4ab2e83d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/300000/296600/296584/acc98380.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Suites-Greenville Greenville 9.0/10 Wonderful (1003) "Very friendly staff and clean rooms " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Craig £85 includes taxes & fees 14 Dec - 15 Dec [](https://www.expedia.co.uk/Greenville-Hotels-Best-Western-Plus-Suites-Greenville.h296584.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/220000/217400/217352/5ca75dae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/220000/217400/217352/0acd51fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillow-top beds, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/220000/217400/217352/3fd407a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillow-top beds, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/220000/217400/217352/92dee2af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Greenville near East Carolina University Greenville 8.6/10 Excellent (387) "Room was clean, the hotel staff gave excellent service everyone was friendly and accommodating. I will be staying at this hotel whenever I go to visit my family." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ericka £91 includes taxes & fees 14 Dec - 15 Dec [](https://www.expedia.co.uk/Greenville-Hotels-Wingate-By-Wyndham-Greenville.h217352.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/110000/102500/102482/30d4a3d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/1000000/110000/102500/102482/fdb16233.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, cots/infant beds](https://images.trvl-media.com/lodging/1000000/110000/102500/102482/c98c2c60.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/110000/102500/102482/faaccec3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Greenville by IHG Greenville 8.4/10 Very good (965) "Great location and breakfast menu " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Angela £84 includes taxes & fees 14 Dec - 15 Dec [](https://www.expedia.co.uk/Greenville-Hotels-Holiday-Inn-Express-Greenville.h102482.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12900/12870/8d14df71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/20000/12900/12870/f0182b89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/20000/12900/12870/ab2264fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/20000/12900/12870/d37ee56a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Greenville by IHG Greenville 8.8/10 Excellent (1000) "Convenient location." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) GEORGE £94 includes taxes & fees 14 Dec - 15 Dec [](https://www.expedia.co.uk/Greenville-Hotels-Holiday-Inn-Greenville.h12870.Hotel-Information) ![In-room safe, blackout curtains, free WiFi, bed sheets](https://images.trvl-media.com/lodging/3000000/2010000/2009600/2009531/2e252281.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2010000/2009600/2009531/a65a8dea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/3000000/2010000/2009600/2009531/bebdabe1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/3000000/2010000/2009600/2009531/16e45970.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Microtel Inn & Suites by Wyndham Greenville/University Medic Greenville 7.2/10 Good (1003) "Staff is nice and friendly " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tonya £52 includes taxes & fees 14 Dec - 15 Dec [](https://www.expedia.co.uk/Greenville-Hotels-Microtel-Inn-Suites-By-Wyndham-GreenvilleUniversity-Medic.h2009531.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/120000/119100/119042/1f6092e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/120000/119100/119042/2deb739b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast and dinner served](https://images.trvl-media.com/lodging/1000000/120000/119100/119042/99c73073.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds | In-room safe, desk, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/120000/119100/119042/2203e988.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard Marriott Greenville Medical District 8.8/10 Excellent (879) "Clean rooms, friendly staff and great location. Enjoyed our stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Frederick £100 includes taxes & fees 14 Dec - 15 Dec [](https://www.expedia.co.uk/Greenville-Hotels-Courtyard-Marriott-Greenville.h119042.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. 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