A historic downtown street with vintage buildings, a church steeple, and a prominent clock tower.

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Check prices for these dates

In two weeks
11 Sept - 13 Sept
In two months
23 Oct - 25 Oct
In three months
20 Nov - 22 Nov
In four months
18 Dec - 20 Dec

Our top choices for Great River Road holiday rentals

A modern kitchen with white cabinets, a stainless steel oven, a microwave, and a refrigerator. There is a dining table with chairs and a ceiling fan.

1. Cozy Studio Cottage on "The Hill," walkably close to everything! The Zoo, Park!!

Cozy Studio Cottage on "The Hill," walkably close to everything! The Zoo, Park!!
The Hill
9.8 out of 10, Exceptional, (196 reviews)
"Looks exactly like the pictures. Clean, beautiful shower. Friendly staff, had no problems answering questions, had all the things you needed to relax for a few days with a couple of friends. The neighborhood is lovely & peaceful at night. Beautiful yard. So pleased I came across this cottage. Thanks guy, our stay was awesome"
United States
Crystal
The price is £115
includes taxes & fees
31 Aug - 1 Sept
Cozy Studio Cottage on "The Hill," walkably close to everything! The Zoo, Park!!
A cabin with a large window, surrounded by trees.

2. Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
2.0 star property
French Village
9.8 out of 10, Exceptional, (99 reviews)
"I really enjoyed my time at the stay !"
United States
Ronrecus
The price is £111
includes taxes & fees
7 Sept - 8 Sept
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
A hotel room with two beds, green walls, and framed pictures of landscapes.

3. Hudson Inn & Suites

Hudson Inn & Suites
3.0 star property
Hudson
8.2 out of 10, Very good, (903 reviews)
"Older hotel but well maintained and great value for the price."
United States
Dennis
The price is £71
includes taxes & fees
31 Aug - 1 Sept
Hudson Inn & Suites
A wooden deck with a view of a park featuring trees and a grassy area.

4. Countryside Private Guest Room

Countryside Private Guest Room
Freeburg
9.8 out of 10, Exceptional, (28 reviews)
"Awesome place to stay really nice host would highly recommend!!!!"
United States
Cayson P.
The price is £71
includes taxes & fees
31 Aug - 1 Sept
Countryside Private Guest Room

5. Turn On Inn

Turn On Inn
3.0 star property
Lake Village
9.6 out of 10, Exceptional, (92 reviews)
"Great accomodstion great price!"
United States
martha
The price is £91
includes taxes & fees
31 Aug - 1 Sept
Turn On Inn
A living room with a wooden entertainment center, a white sofa, and a dining area with a white railing.

6. Spacious, cozy home in Saint Louis

Spacious, cozy home in Saint Louis
St. Louis
10.0 out of 10, Exceptional, (44 reviews)
"Was very clean and very quit neighborhood"
United States
Judith H.
The price is £226
includes taxes & fees
31 Aug - 1 Sept
Spacious, cozy home in Saint Louis
A field of lavender with a path leading through it.

7. Tamarack Point Homestead

Tamarack Point Homestead
Arcadia
10.0 out of 10, Exceptional, (42 reviews)
"What a wonderful place to stay. "
United States
Anonymous traveller
The price is £90
includes taxes & fees
31 Aug - 1 Sept
Tamarack Point Homestead
A row of single-family homes with a well-maintained lawn and a tree in the foreground.

8. Nauvoo Vacation Villas & Condos

Nauvoo Vacation Villas & Condos
3.0 star property
Nauvoo
9.8 out of 10, Exceptional, (441 reviews)
"Staff were very helpful. Wonderful place. Qoiet and clean"
United States
Carrie
The price is £113
includes taxes & fees
31 Aug - 1 Sept
Nauvoo Vacation Villas & Condos
A modern room with large windows overlooking a lake, a cozy seating area, and a fireplace.

9. Nature Link Resort

Nature Link Resort
3.0 star property
Nisswa
9.8 out of 10, Exceptional, (95 reviews)
"Very quiet and clean. Good couples getaway"
United States
Kari
The price is £165
includes taxes & fees
27 Sept - 28 Sept
Nature Link Resort
A wooden cabin with a green door, a number '2' sign, a small porch with a wooden railing, and a wall-mounted lantern.

10. 3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!

3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!
Makanda
9.8 out of 10, Exceptional, (73 reviews)
"Very clean and comfortable stay"
United States
Alison K.
The price is £137
includes taxes & fees
31 Aug - 1 Sept
3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!
A hotel room with a large bed, a small table with a bottle and fruit, a chair, a lamp, and a framed picture on the wall.

11. Roami at The Fitz

Roami at The Fitz
4.0 star property
Downtown St. Paul
8.8 out of 10, Excellent, (62 reviews)
"Clean spacious rooms, pleasant staff, great amenities and convenient location. We enjoyed our stay and would book again"
United States
Linda
The price is £56
includes taxes & fees
30 Sept - 1 Oct
Roami at The Fitz
A room with a bench, a wall-mounted sign, and a potted plant.

12. Ranch styled home, in a quiet neighborhood, totally remodeled in 2020.

Ranch styled home, in a quiet neighborhood, totally remodeled in 2020.
Bellevue
9.8 out of 10, Exceptional, (126 reviews)
"Super convenient and comfy place to stay in the Bellevue area."
United States
Bruce B.
The price is £152
includes taxes & fees
1 Sept - 2 Sept
Ranch styled home, in a quiet neighborhood, totally remodeled in 2020.
A modern kitchen with white cabinets, stainless steel appliances, and a wooden floor.

13. Spacious & Modern 2BR Home with Attached Garage

Spacious & Modern 2BR Home with Attached Garage
Quincy
10.0 out of 10, Exceptional, (50 reviews)
"Nicely decorated and very comfortable."
United States
Marsha
Spacious & Modern 2BR Home with Attached Garage
A modern kitchen with a marble countertop, white cabinets, and a built-in dishwasher.

14. NEW Modern & Luxe 5BDR House. Sleep 14. Downtown 5min away

NEW Modern & Luxe 5BDR House. Sleep 14. Downtown 5min away
The Gate
9.6 out of 10, Exceptional, (43 reviews)
"Great stay!"
United States
MaryAnn V.
NEW Modern & Luxe 5BDR House. Sleep 14. Downtown 5min away
A stone wall with a sign reading "Peter Ray House" in front of a textured wall.

15. Peter Ray House

Peter Ray House
Maeystown
10.0 out of 10, Exceptional, (75 reviews)
"This house was incredible. Loved the history and ambience of the town. Peter was one of the nicest homes I’ve stayed in over the years. I would highly recommend it."
United States
Eric
The price is £165
includes taxes & fees
2 Sept - 3 Sept
Peter Ray House
A log cabin with a metal roof, two windows, a door, and a porch with two rocking chairs and a small table.

16. Rest, Relax and Renew. Our log cabin experience awaits your arrival.

Rest, Relax and Renew. Our log cabin experience awaits your arrival.
Anna
10.0 out of 10, Exceptional, (424 reviews)
The price is £152
includes taxes & fees
2 Sept - 3 Sept
Rest, Relax and Renew. Our log cabin experience awaits your arrival.
A cozy cabin interior with a stone fireplace, wooden walls, and various framed pictures.

17. Pine Cabin #3 on 30 Acres! 1 mi. from Carbondale, IL & SIUC Campus

Pine Cabin #3 on 30 Acres! 1 mi. from Carbondale, IL & SIUC Campus
Carbondale
9.2 out of 10, Wonderful, (152 reviews)
"If your looking for a quite out of the way place this is it."
United States
James B.
The price is £115
includes taxes & fees
31 Aug - 1 Sept
Pine Cabin #3 on 30 Acres! 1 mi. from Carbondale, IL & SIUC Campus
A modern hotel room with a large window, a grey sofa, a wooden coffee table, a bed, and a view of a church spire.

18. Roami at Century Plaza

Roami at Century Plaza
4.0 star property
Downtown Minneapolis
9.4 out of 10, Exceptional, (67 reviews)
"Expectations meet and exceed, would stay here again"
United States
Martin M
The price is £78
includes taxes & fees
7 Sept - 8 Sept
Roami at Century Plaza
A small blue shed with a white door, a patio with a table and chairs, and a wooden fence with plants.

19. The Alton House - Come experience tiny house living in beautiful Pepin!

The Alton House - Come experience tiny house living in beautiful Pepin!
Pepin
9.8 out of 10, Exceptional, (46 reviews)
"Amazing little place. Very clean and organized."
United States
Chris K.
The price is £146
includes taxes & fees
31 Aug - 1 Sept
The Alton House - Come experience tiny house living in beautiful Pepin!
A white two-story house with a covered porch, a chimney, and a small garden area with chairs and a table.

20. Beautiful Modern Loft In Wine Country!

Beautiful Modern Loft In Wine Country!
Ste. Genevieve
10.0 out of 10, Exceptional, (288 reviews)
The price is £152
includes taxes & fees
2 Sept - 3 Sept
Beautiful Modern Loft In Wine Country!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Great River Road Hotel Reviews

AmericInn by Wyndham Prairie du Chien

AmericInn by Wyndham Prairie du Chien

8/10 Good
"Room was musty smelling and shower had a moldy ceiling. Breakfast was good."
Lori 1-night trip
Posted 7 hours ago
AmericInn by Wyndham Prairie du Chien
Les Carillons - Arts District Gem Large Groups Welcome! Pool! Elevator!

Les Carillons - Arts District Gem Large Groups Welcome! Pool! Elevator!

10/10 Excellent
"Lee Ann is a wonderful host, and my group and I thoroughly enjoyed our stay. The location is ideal with local bars and restaurants in the immediate vicinity, but it's still walkable to Bourbon St and the Superdome. The house is spacious and amenities like towels and shampoo were plentiful. Pool access was easy and the leftover sunscreen and festive hats were much appreciated. We would absolutely stay here again."
Ed Q. 3-night trip
Posted 12 days ago
Les Carillons - Arts District Gem Large Groups Welcome! Pool! Elevator!

Find out more about Great River Road

Everything you need to know about Great River Road holiday rentals

Whether you’re excited for the perfect family holiday, a romantic getaway for two, or the ultimate city break, we’ve got the Great River Road holiday rental for you. At Expedia, you can take your pick from private holiday homes, apartments, cottages, apart-hotels, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Great River Road holiday rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. 

Great River Road holiday rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Great River Road. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in . 

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Great River Road holiday rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a holiday rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Great River Road holiday rentals we have selected for you start as low as per night. Entering your travel dates in the search wizard you might find even better deals!

How to find incredible deals on Great River Road rentals

At Expedia, we put the best Great River Road holiday rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. 

To find some top Great River Road rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Great River Road holiday.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Great River Road. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.