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Independent hotels in Florida Keys, Florida

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Featured Florida Keys Independent Hotels

See all 390 Hotels in Florida Keys
Santa Maria Suites

Santa Maria Suites

1401 Simonton St, Key West
4.0 out of 5.0
4.8 out of 5 (365 reviews)
beautiful! Room was like an apartment rather than a hotel. Top notch all the way! I'm spoiled now - … - 

£245

£245
Cheeca Lodge & Spa

Cheeca Lodge & Spa

81801 Overseas Highway, Mile Marker 82, Islamorada
4.0 out of 5.0
4.4 out of 5 (644 reviews)
Wedding We had our wedding there. Went off without a flaw. Would do the same in a beartbeat. Thank you ! - 

£134

£134
Key West Escapes - Luxury Yoga Vacations

Key West Escapes - Luxury Yoga Vacations

Tropical Street, Key West
4.0 out of 5.0
Tranquility Bay Beachfront Hotel and Resort

Tranquility Bay Beachfront Hotel and Resort

2600 Overseas Hwy, Marathon
4.0 out of 5.0
4.5 out of 5 (462 reviews)
Nice hotel but staff could be a little better. Nice hotel on Route 1 and on the beach. Facilities are well maintained, but desk did not tell us th … - 

£191

£191
Oceans Edge Key West Hotel & Marina

Oceans Edge Key West Hotel & Marina

5950 Peninsular Avenue, Key West
3.5 out of 5.0
4.4 out of 5 (83 reviews)
Gorgeous hotel! Loved this hotel! There is room for improvement, though. Swimming pools should be open past 10:00, … - 

£126

£126
The Gardens Hotel

The Gardens Hotel

526 Angela Street, Key West
4.0 out of 5.0
4.8 out of 5 (115 reviews)
Best breakfast... Great location , friendly staff. Parking was limited - 

£164

£164
Key West Yacht Life

Key West Yacht Life

Key West Harbour Yacht Club Stock Island, Key West
4.0 out of 5.0
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Pocket Guides: Independent Hotels in Florida Keys

Find Independent Hotels in the Florida Keys

The Florida Keys is separate from the rest of the United States both geographically and in spirit. These quirky laid-back islands dance to the beat of their own drum, making them natural territory for independent hotels. From Key Largo at the top of the island chain to Key West at the southern tip, you’ll find independent one-of-a-kind properties all the way down the Overseas Highway.

Unique Florida Keys Hotels

For independent hotels in easy reach of the dive sites the Florida Keys are famous for, check in to a waterfront bed and breakfast in Key Largo, where the Keys’ famous offshore living coral reef extends for miles.

If you’d rather be at the heart of a traditional seaside town with the seafood restaurants that go with it, choose a quirky guesthouse in Marathon, right in the middle of the Florida Keys. And for the nightlife and sunset celebrations of Key West, check in to a historic cottage in downtown.

Wherever you choose an independent hotel, expect a homely atmosphere, service with a personal touch and a warm Conch welcome.

Florida Keys’ Independent Hotels for All Budgets

Upscale independent hotels in the Florida Keys range from small properties with a handful of perfectly furnished rooms to big resort hotels with their own stretch of private beach. You can cherry-pick your base, maybe a peaceful bolthole tucked quietly away from the crowds in the Middle Keys, or a well-positioned hotel right at the heart of the action in lively Key West or the sport fishing hub of Islamorada.

Luxury independent hotels in the Florida Keys vary wildly in style. There are chic beachfront cottages in prime positions on private beaches, polished resort hotels with infinity pools and tiny backstreet guesthouses with modern art on the walls and flashy mod cons in the bedrooms.

Independent hotels don’t have to put a huge a dent in your wallet. No-frills motels and affordable bed and breakfasts, you’ll find them on the outskirts of central Key West, in the traditional seafaring town of Marathon and close to the diving centres of Key Largo. And each one has all the quirky charm you’d expect from these free-spirited islands.