Search Hotels by Independent in Florida Keys from £86
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Top Florida Keys Independent Hotels

Amara Cay Resort
Amara Cay Resort

Cheeca Lodge & Spa
Cheeca Lodge & Spa

Bayside Inn Key Largo
Bayside Inn Key Largo

Chesapeake Beach Resort
Chesapeake Beach Resort

Creekside Inn Islamorada
Creekside Inn Islamorada

La Siesta Resort & Villas
La Siesta Resort & Villas

Lime Tree Bay Resort
Lime Tree Bay Resort

Coconut Cay Resort & Marina
Coconut Cay Resort & Marina
Find out more about Florida Keys
Find out more about Florida Keys
Pocket Guides: Independent Hotels in Florida Keys
Find Independent Hotels in the Florida Keys
The Florida Keys is separate from the rest of the United States both geographically and in spirit. These quirky laid-back islands dance to the beat of their own drum, making them natural territory for independent hotels. From Key Largo at the top of the island chain to Key West at the southern tip, you’ll find independent one-of-a-kind properties all the way down the Overseas Highway.
Unique Florida Keys Hotels
For independent hotels in easy reach of the dive sites the Florida Keys are famous for, check in to a waterfront bed and breakfast in Key Largo, where the Keys’ famous offshore living coral reef extends for miles.
If you’d rather be at the heart of a traditional seaside town with the seafood restaurants that go with it, choose a quirky guesthouse in Marathon, right in the middle of the Florida Keys. And for the nightlife and sunset celebrations of Key West, check in to a historic cottage in downtown.
Wherever you choose an independent hotel, expect a homely atmosphere, service with a personal touch and a warm Conch welcome.
Florida Keys’ Independent Hotels for All Budgets
Upscale independent hotels in the Florida Keys range from small properties with a handful of perfectly furnished rooms to big resort hotels with their own stretch of private beach. You can cherry-pick your base, maybe a peaceful bolthole tucked quietly away from the crowds in the Middle Keys, or a well-positioned hotel right at the heart of the action in lively Key West or the sport fishing hub of Islamorada.
Luxury independent hotels in the Florida Keys vary wildly in style. There are chic beachfront cottages in prime positions on private beaches, polished resort hotels with infinity pools and tiny backstreet guesthouses with modern art on the walls and flashy mod cons in the bedrooms.
Independent hotels don’t have to put a huge a dent in your wallet. No-frills motels and affordable bed and breakfasts, you’ll find them on the outskirts of central Key West, in the traditional seafaring town of Marathon and close to the diving centres of Key Largo. And each one has all the quirky charm you’d expect from these free-spirited islands.
Florida Keys Hotel Reviews
Florida Keys Hotel Reviews

Bayside Inn Key Largo
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Explore more hotels
- Reefhouse Resort & Marina
- Playa Largo Resort & Spa, Autograph Collection
- Waterside Suites & Marina
- Lime Tree Bay Resort
- La Siesta Resort & Villas
- Marina Del Mar Resort and Marina
- Faro Blanco Resort & Yacht Club Marathon, Curio by Hilton
- Courtyard by Marriott Faro Blanco Resort
- Holiday Inn Key Largo by IHG
- Rock Reef Resort
- Creekside Inn Islamorada
- Tranquility Bay Beachfront Hotel and Resort
- The Pelican Key Largo Cottages
- Coconut Cay Resort & Marina
- Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
- Hadley Resort and Marina
- Drift Hotel
- Fisher Inn Resort & Marina
- Dove Creek Resort & Marina, Trademark Collection by Wyndham
- Sunset Cove Beach Resort