Title: TOP Boutique Hotels in Florida Keys for 2025 | Expedia.co.uk [Florida Keys Travel Guide](https://expedia.co.uk/Florida-Keys.dx6023765)[Hotels in Florida Keys](https://expedia.co.uk/Florida-Keys-Hotels.d6023765.Travel-Guide-Hotels)[Holiday Rentals in Florida Keys](https://expedia.co.uk/Florida-Keys-Holiday-Rentals.d6023765.Travel-Guide-HolidayRentals)[Flights to Florida Keys](https://expedia.co.uk/Cheap-Flights-To-Florida-Keys.d6023765.Travel-Guide-Flights)[Things to do in Florida Keys](https://expedia.co.uk/Things-To-Do-In-Florida-Keys.d6023765.Travel-Guide-Activities)[Florida Keys Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Florida-Keys.d6023765.Car-Hire-Guide)[Florida Keys Holidays](https://expedia.co.uk/Florida-Keys.d6023765.Holidays-City-Breaks) ![Higgs Beach showing tropical scenes and a beach as well as a large group of people](https://images.trvl-media.com/place/6246822/f00ad239-b8ad-4f0c-b162-acc6426db1e2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Boutique Hotels in Florida Keys - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Florida Keys Boutique Hotels Tonight [27 Nov - 28 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6023765&startDate=2025-11-27&endDate=2025-11-28&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [28 Nov - 29 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6023765&startDate=2025-11-28&endDate=2025-11-29&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [28 Nov - 30 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6023765&startDate=2025-11-28&endDate=2025-11-30&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [5 Dec - 7 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6023765&startDate=2025-12-05&endDate=2025-12-07&adults=2&propertyStyle=BOUTIQUE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Florida Keys Boutique Hotels ![On the beach, kayaking](https://images.trvl-media.com/lodging/4000000/3920000/3911700/3911616/b6383084.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Celeste Deluxe Sea View Suite | Living area | 35-inch flat-screen TV with satellite channels, TV](https://images.trvl-media.com/lodging/4000000/3920000/3911700/3911616/b9dfb26d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aquamarina Deluxe Sea View Suite | Living area | 35-inch flat-screen TV with satellite channels, TV](https://images.trvl-media.com/lodging/4000000/3920000/3911700/3911616/9f59701c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![La Palma Tropical Garden Suite | Private kitchen | Fridge, microwave, dishwasher, coffee/tea maker](https://images.trvl-media.com/lodging/4000000/3920000/3911700/3911616/5d87a0b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Azul del Mar Key Largo 9.0/10 Wonderful (784) "Room was spotless and staff was more than accommodating!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Windy £83 includes taxes & fees 7 Dec - 8 Dec [](https://www.expedia.co.uk/Key-Largo-Hotels-Azul-Del-Mar.h3911616.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/1000000/10000/300/217/c6778dc1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/10000/300/217/b191a829.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/10000/300/217/dc75eb36.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/10000/300/217/8e70662e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Amsterdam's Curry Mansion Inn Key West Historic District 8.4/10 Very good (1011) "The poolside seating was very nice. It was very comfortable. It was a nice being able to grab extra items if needed beside the washer and dryer. Our room even came with Tide Laundry Detergent and extra pool towels. We would definitely stay here again! It was so convenient to everything on Duval Street. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mary £197 includes taxes & fees 30 Nov - 1 Dec [](https://www.expedia.co.uk/Key-West-Hotels-Amsterdams-Curry-Mansion-Inn.h217.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/3000000/2490000/2480500/2480462/20df0c8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/3000000/2490000/2480500/2480462/9d978c12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor spa tub](https://images.trvl-media.com/lodging/3000000/2490000/2480500/2480462/bc36c28b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/3000000/2490000/2480500/2480462/c253b646.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Artist House Key West Key West Historic District 9.8/10 Exceptional (417) "Great location one block off of Duval St and central to everything. Beautiful accommodations in a safe area, hot showers, comfortable beds, and delicious complimentary breakfast. The staff was great and very accommodating. I loved sitting on the front porch to people watch and read in the afternoon. I would definitely stay here again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Debra £156 includes taxes & fees 2 Dec - 3 Dec [](https://www.expedia.co.uk/Key-West-Hotels-Artist-House-Key-West.h2480462.Hotel-Information) ![Premium bedding, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/2000000/1750000/1749500/1749434/c579b899.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/2000000/1750000/1749500/1749434/83214581.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/2000000/1750000/1749500/1749434/f17f7f22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/2000000/1750000/1749500/1749434/3347744a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Weatherstation Inn Old Town Key West 9.4/10 Exceptional (986) "Nice place to stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Victoria £198 includes taxes & fees 15 Dec - 16 Dec [](https://www.expedia.co.uk/Key-West-Hotels-Weatherstation-Inn.h1749434.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/1000000/20000/17800/17764/ca282d01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/1000000/20000/17800/17764/fd222c6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, Frette Italian sheets, premium bedding, down duvets](https://images.trvl-media.com/lodging/1000000/20000/17800/17764/0c06d3a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sports court](https://images.trvl-media.com/lodging/1000000/20000/17800/17764/eece937d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Beacon Hotel South Beach South Beach 7.8/10 Good (2710) "Great location! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Pavel £77 includes taxes & fees 9 Dec - 10 Dec [](https://www.expedia.co.uk/Miami-Hotels-Beacon-Hotel-South-Beach.h17764.Hotel-Information) ![Nightclub](https://images.trvl-media.com/lodging/5000000/4040000/4037100/4037044/48151264.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee shop](https://images.trvl-media.com/lodging/5000000/4040000/4037100/4037044/52098694.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bicycling](https://images.trvl-media.com/lodging/5000000/4040000/4037100/4037044/d26f630b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/5000000/4040000/4037100/4037044/eba6849a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Breakwater South Beach South Beach 7.8/10 Good (1040) "Location is great " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Ryan £92 includes taxes & fees 16 Dec - 17 Dec [](https://www.expedia.co.uk/Miami-Hotels-Hotel-Breakwater-South-Beach.h4037044.Hotel-Information) ![2 outdoor pools, a heated pool, pool cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/1000000/10000/7200/7154/1287769b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/1000000/10000/7200/7154/c035f815.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/1000000/10000/7200/7154/9bd5cd17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![City Studio Suite | 1 bedroom, premium bedding, down duvets, in-room safe](https://images.trvl-media.com/lodging/1000000/10000/7200/7154/b01343a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### National Hotel, An Adult Only Oceanfront Resort South Beach 9.0/10 Wonderful (1609) "The hotel was amazing and so were the staff. We loved our stay and cannot wait to come back! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dawn £182 includes taxes & fees 17 Dec - 18 Dec [](https://www.expedia.co.uk/Miami-Hotels-National-Hotel.h7154.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/70000/67900/67841/cffa88f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/70000/67900/67841/10baf87c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/1000000/70000/67900/67841/3667389e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/1000000/70000/67900/67841/c5f460b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Clevelander Hotel – Adults Only South Beach 7.4/10 Good (1013) "Great location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shelia £121 includes taxes & fees 15 Dec - 16 Dec [](https://www.expedia.co.uk/Miami-Hotels-Clevelander-Hotel-Adults-Only.h67841.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/460000/455900/455826/aa113675.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/460000/455900/455826/4db173c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, down duvets, minibar](https://images.trvl-media.com/lodging/1000000/460000/455900/455826/98d11db7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, down duvets, minibar](https://images.trvl-media.com/lodging/1000000/460000/455900/455826/w4238h2830x6y0-fd4dcdca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Whitelaw Hotel South Beach 7.0/10 Good (1004) "Loved the restaurant on the property. Very friendly staff, treated us like family. Not a fancy place to stay but very hospitable. Excellent location. Enjoyed my stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christopher £66 includes taxes & fees 9 Dec - 10 Dec [](https://www.expedia.co.uk/Miami-Hotels-The-Whitelaw-Hotel.h455826.Hotel-Information) ![Nightclub](https://images.trvl-media.com/lodging/1000000/10000/3800/3792/b52bbb8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/10000/3800/3792/d1684d46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/3800/3792/9b3bf772.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, soundproofing, iron/ironing board, free Internet](https://images.trvl-media.com/lodging/1000000/10000/3800/3792/f8873caf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Essex House By Clevelander South Beach 7.6/10 Good (1029) "Had a great stay. Would stay again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Letitia £98 includes taxes & fees 8 Dec - 9 Dec [](https://www.expedia.co.uk/Miami-Hotels-Essex-House-By-Clevelander.h3792.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-12-11&endDate=2025-12-12®ionId=6023765&adults=2&specialized_stays_group_explore=boutique_property&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2025/11/05/BEX-BF-25_FR-DE-MX-UK_1_Desktop.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## Black Friday Sale Save up to 40% on select hotels. [Book now](https://expedia.co.uk/cheap-deals?rfrr=AFFINITY_BF_PROMO_6023765) ## Top Florida Keys Hotel Reviews ![Amara Cay Resort](https://images.trvl-media.com/lodging/1000000/70000/62000/61976/84b50729_y.jpg) ### Amara Cay Resort 10/10 Excellent "This resort was beautiful, clean and fantastic. The staff was friendly and helpful. We had a wonderful day and will be back." [](https://expedia.co.uk/Islamorada-Hotels-Amara-Cay-Resort.h61976.Hotel-Information) ## Explore a world of travel with Expedia - Accommodation - Packages - More ways to book - [Hotels near John Pennekamp Coral Reef State Park](https://www.expedia.co.uk/John-Pennekamp-Coral-Reef-State-Park-Hotels.0-l6068611-0.Travel-Guide-Filter-Hotels) - [John Pennekamp Coral Reef State Park](https://www.expedia.co.uk/John-Pennekamp-Coral-Reef-State-Park-United-States-of-America.d6068611.Attraction) - [Book Boutique Hotels in Florida Keys on Expedia.com](https://www.expedia.com/Florida-Keys-Hotels-Boutique-Hotel.0-0-d6023765-tBoutiqueHotel.Travel-Guide-Filter-Hotels)