Title: Hotels in East Cape Girardeau, IL - Best East Cape Girardeau Hotels from £50 - Fully Refundable Options - Expedia.co.uk [Holiday Rentals in East Cape Girardeau](https://expedia.co.uk/East-Cape-Girardeau-Holiday-Rentals.d553248634983574328.Travel-Guide-HolidayRentals)[East Cape Girardeau Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-East-Cape-Girardeau.d553248634983574328.Car-Hire-Guide)[East Cape Girardeau Holidays](https://expedia.co.uk/East-Cape-Girardeau.d553248634983574328.Holidays-City-Breaks) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in East Cape Girardeau, IL from £50 ![price find illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in East Cape Girardeau Pool [](https://www.expedia.co.uk/Hotel-Search?destination=East+Cape+Girardeau%2C+Illinois%2C+United+States+of+America®ionId=553248634983574328&latLong=37.295884%2C-89.496202&adults=2&startDate=2025-10-18&d1=2025-10-18&endDate=2025-10-20&d2=2025-10-20&amenities=POOL) Family friendly [](https://www.expedia.co.uk/Hotel-Search?destination=East+Cape+Girardeau%2C+Illinois%2C+United+States+of+America®ionId=553248634983574328&latLong=37.295884%2C-89.496202&adults=2&startDate=2025-10-18&d1=2025-10-18&endDate=2025-10-20&d2=2025-10-20&travelerType=family_friendly) Pet friendly [](https://www.expedia.co.uk/Hotel-Search?destination=East+Cape+Girardeau%2C+Illinois%2C+United+States+of+America®ionId=553248634983574328&latLong=37.295884%2C-89.496202&adults=2&startDate=2025-10-18&d1=2025-10-18&endDate=2025-10-20&d2=2025-10-20&amenities=PETS) ## Check prices for these dates Tonight [4 Oct - 5 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248634983574328&startDate=2025-10-04&endDate=2025-10-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [5 Oct - 6 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248634983574328&startDate=2025-10-05&endDate=2025-10-06&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [10 Oct - 12 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248634983574328&startDate=2025-10-10&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [17 Oct - 19 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248634983574328&startDate=2025-10-17&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top 10 East Cape Girardeau hotels and places to stay ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/66c21f7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/fbb12bb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/41100/41077/d0828685.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Jackson MO Jackson 9.6/10 Exceptional (1005) "Was a clean room, nice staff, good parking " £71 includes taxes & fees 9 Oct - 10 Oct [](https://www.expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/05fcda41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/23518830.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Single Room, 1 King Bed, Non Smoking (Mobility, Bathtub w/Grab Bars) | Hypo-allergenic bedding, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/67f5d6f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/54000000/53350000/53348100/53348099/47fa1edf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau Jackson 8.8/10 Excellent (631) "We had a restful stay very safe & clean! Friendly staff:)" £68 includes taxes & fees 7 Oct - 8 Oct [](https://www.expedia.co.uk/Jackson-Hotels-La-Quinta-Inn-Suites-By-Wyndham-JacksonCape-Girardeau.h53348099.Hotel-Information) ![Free daily on-the-go breakfast ](https://images.trvl-media.com/lodging/9000000/8300000/8295800/8295732/8928d3dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/9000000/8300000/8295800/8295732/3bfecde9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/9000000/8300000/8295800/8295732/90183327.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/9000000/8300000/8295800/8295732/d71f43c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel 7 Inn Anna Anna 6.6/10 (211) "The staff was wonderful" £66 includes taxes & fees 5 Oct - 6 Oct [](https://www.expedia.co.uk/Anna-Hotels-Hotel-7-Inn-Anna.h8295732.Hotel-Information) ![Economy Single Room, 1 Queen Bed, Kitchenette | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/5eb3395a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/6f6795dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Economy Single Room, 1 Queen Bed, Kitchenette | Bathroom | Hair dryer, towels](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/324e501c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Economy Single Room, 1 Queen Bed, Kitchenette | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/5dd1852e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Town House Inn Jackson 7.6/10 Good (416) "It was easy and quiet and an easy check in " £52 includes taxes & fees 6 Oct - 7 Oct [](https://www.expedia.co.uk/Sikeston-Hotels-Town-House-Inn.h11613476.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/032aa313.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/a085469e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout curtains, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/284f2de7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pear Tree Inn Cape Girardeau West Cape Girardeau 9.0/10 Wonderful (1003) "My room was clean and I was very close to shopping and restaurants. I really enjoyed my stay there." £59 includes taxes & fees 5 Oct - 6 Oct [](https://www.expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/7a520031.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/ee6292b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/da4fe5e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/4ea3df4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pear Tree Inn Cape Girardeau Near the Medical Center Cape Girardeau 9.0/10 Wonderful (1003) "Room was clean, it is an affordable option to stay for a day or two " £59 includes taxes & fees 5 Oct - 6 Oct [](https://www.expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/fe49057f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/479dc559.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 8 AM to 11 PM, pool loungers](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/64fb9857.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down duvets, pillow-top beds, in-room safe](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/eb2507f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG Cape Girardeau 9.4/10 Exceptional (1002) "It was right off the interstate with lots of restaurant options " £79 includes taxes & fees 19 Oct - 20 Oct [](https://www.expedia.co.uk/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information) ![Business centre](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/4b521966.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/c56432e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/356238c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/40900/40831/05f90b2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Cape Girardeau Cape Girardeau 9.4/10 Exceptional (1000) "Excellent place. Really friendly staff" £75 includes taxes & fees 12 Oct - 13 Oct [](https://www.expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/16f1820b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/2d914387.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/c279dc08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Plaza Hotel Cape Girardeau Conference Center Cape Girardeau 9.6/10 Exceptional (1008) "Great place" £75 includes taxes & fees 12 Oct - 13 Oct [](https://www.expedia.co.uk/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/ae49c8da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/18325925.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/927db718.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast and dinner served, American cuisine](https://images.trvl-media.com/lodging/25000000/24330000/24322100/24322039/20bc712d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Cape Girardeau Downtown Cape Girardeau 9.6/10 Exceptional (454) "The Staff was friendly The restaurant was good" £105 includes taxes & fees 19 Oct - 20 Oct [](https://www.expedia.co.uk/Sikeston-Hotels-Courtyard-By-Marriott-Cape-Girardeau-Downtown.h24322039.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/70460e25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast ](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/eec0e02a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/06dc4487.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/3000000/2560000/2555900/2555896/a758bb0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites Jackson-Cape Girardeau Jackson 8.2/10 Very good (734) "Great area, fast check in, quiet, very spacious" £71 includes taxes & fees 5 Oct - 6 Oct [](https://www.expedia.co.uk/Sikeston-Hotels-Comfort-Suites-Jackson-Cape-Girardeau.h2555896.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/d2a0e781.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily English breakfast ](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/e034ecf9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/dc836bc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, down duvets, memory-foam beds](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/c5d3f974.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Cape Girardeau 7.2/10 Good (646) "nice stay" £50 includes taxes & fees 16 Oct - 17 Oct [](https://www.expedia.co.uk/Sikeston-Hotels-Quality-Inn.h855988.Hotel-Information) ![Courtyard](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/540ce58d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave | In-room safe, desk, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/4c2e6495.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/0578314a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/13000000/12790000/12786700/12786627/acc0b9b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Cape Girardeau I 55 East Cape Girardeau 9.6/10 Exceptional (748) "Would prefer onsite restaurant and bar" £92 includes taxes & fees 19 Oct - 20 Oct [](https://www.expedia.co.uk/Sikeston-Hotels-Hampton-Inn-Cape-Girardeau-I-55-East.h12786627.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/347bcd98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/51a3fe78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/6cd5cd8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/266a85bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Cape Girardeau Cape Girardeau 9.4/10 Exceptional (129) "Excellent hotel…" £78 includes taxes & fees 12 Oct - 13 Oct [](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Fairfield-Inn-Suites-By-Marriott-Cape-Girardeau.h99972043.Hotel-Information) ![Standard Room, 1 Queen Bed, Non Smoking, Garden View | Free WiFi](https://images.trvl-media.com/lodging/106000000/105490000/105486900/105486893/fc499141.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/106000000/105490000/105486900/105486893/a102ce70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/106000000/105490000/105486900/105486893/dbe031d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking | Free WiFi](https://images.trvl-media.com/lodging/106000000/105490000/105486900/105486893/000a3467.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rockwood Inn Cape Girardeau 10/10 Exceptional (16) "We came into town for a concert and had a blast! The hotel was super comfy, and the staff were friendly. The rooms were very clean and the decor was beautiful! " £117 includes taxes & fees 12 Oct - 13 Oct [](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Rockwood-Inn.h105486893.Hotel-Information) ![Room, 2 Queen Beds](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/w3837h2560x3y0-1bbb6bc9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Snack bar](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/c1fba8f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/5aa6a52b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/633eb669.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru By Hilton Cape Girardeau Cape Girardeau 9.6/10 Exceptional (71) "Property is new and very modern - great breakfast" £85 includes taxes & fees 12 Oct - 13 Oct [](https://www.expedia.co.uk/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/53cb7546.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/363ef183.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily to-go breakfast for a fee](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/de11c650.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Riverview Cape Girardeau 9.4/10 Exceptional (429) "Location was perfect for family weekend!" £103 includes taxes & fees 19 Oct - 20 Oct [](https://www.expedia.co.uk/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/6afa6c85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/cc0ef67f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic Area](https://images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/4de18ac4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, in-room safe, desk, blackout curtains](https://images.trvl-media.com/lodging/4000000/3540000/3530400/3530303/bf83e8f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Candlewood Suites Cape Girardeau by IHG Cape Girardeau 8.0/10 Very good (852) "Great staff and convenient location " £69 includes taxes & fees 12 Oct - 13 Oct [](https://www.expedia.co.uk/Sikeston-Hotels-Candlewood-Suites-Cape-Girardeau.h3530303.Hotel-Information) ![Desk, free WiFi](https://images.trvl-media.com/lodging/12000000/11620000/11613900/11613884/7adb4452.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, free WiFi](https://images.trvl-media.com/lodging/12000000/11620000/11613900/11613884/c3f8959c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free self-parking](https://images.trvl-media.com/lodging/12000000/11620000/11613900/11613884/5d555857.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/12000000/11620000/11613900/11613884/674edecd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Town House Inn Cape Giradreau Cape Girardeau 6.0/10 (197) "Staff could have used more training. But overall it was a good experience " £56 includes taxes & fees 5 Oct - 6 Oct [](https://www.expedia.co.uk/Sikeston-Hotels-Town-House-Inn-Cape-Giradreau.h11613884.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-18&endDate=2025-10-19®ionId=553248634983574328&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FEast-Cape-Girardeau-Hotels.d553248634983574328.Travel-Guide-Hotels)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FEast-Cape-Girardeau-Hotels.d553248634983574328.Travel-Guide-Hotels) ## Top East Cape Girardeau Hotel Reviews ![Pear Tree Inn Cape Girardeau West](//images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89_y.jpg) ### Pear Tree Inn Cape Girardeau West 10/10 Excellent "The room was very clean. Parking was very easy. Check in was very easy and the staff was great" [](https://expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) ![Pear Tree Inn Cape Girardeau Near the Medical Center](//images.trvl-media.com/lodging/1000000/50000/40200/40113/7a520031_y.jpg) ### Pear Tree Inn Cape Girardeau Near the Medical Center 10/10 Excellent "Very convenient and felt safe" [](https://expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information) ![Drury Plaza Hotel Cape Girardeau Conference Center](//images.trvl-media.com/lodging/18000000/17270000/17270000/17269948/742aaf1e_y.jpg) ### Drury Plaza Hotel Cape Girardeau Conference Center 10/10 Excellent "This is the best hotel experience for the price that I’ve ever had, and I travel a lot. Very generous social time with three free drinks and lots of complementary food. Everyone was lovely, bed comfortable, perfect temperature and no stale smell. Very clean. And so well priced! I wish all hotels were like this one!" [](https://expedia.co.uk/Sikeston-Hotels-Drury-Plaza-Hotel-Cape-Girardeau-Conference-Center.h17269948.Hotel-Information) ![The Riverview](//images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046_y.jpg) ### The Riverview 10/10 Excellent "Hotel was very close to the Show Me Center. Very clean, quiet and comfortable room." [](https://expedia.co.uk/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information) ![Drury Inn & Suites Jackson MO](//images.trvl-media.com/lodging/1000000/50000/41100/41077/8996a36d_y.jpg) ### Drury Inn & Suites Jackson MO 10/10 Excellent "We just came in for one night to see our grandson play football. We come to Jackson often and always stay here. It is consistently excellent. Clean, friendly, staff is great. " [](https://expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Jackson-MO.h41077.Hotel-Information) ![Drury Inn & Suites Cape Girardeau](//images.trvl-media.com/lodging/1000000/50000/40900/40831/4b521966_y.jpg) ### Drury Inn & Suites Cape Girardeau 10/10 Excellent "Clean, comfortable, spacious " [](https://expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information) ![Tru By Hilton Cape Girardeau](//images.trvl-media.com/lodging/112000000/111600000/111590900/111590879/w3837h2560x3y0-1bbb6bc9_y.jpg) ### Tru By Hilton Cape Girardeau 10/10 Excellent "Everyone was so nice, patient & kind. Breakfast was delicious. The stay was awesome. " [](https://expedia.co.uk/Cape-Girardeau-Hotels-Tru-By-Hilton-Cape-Girardeau.h111590879.Hotel-Information) ![Fairfield Inn & Suites by Marriott Cape Girardeau](//images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/347bcd98_y.jpg) ### Fairfield Inn & Suites by Marriott Cape Girardeau 10/10 Excellent "Excellent hotel…" [](https://expedia.co.uk/Cape-Girardeau-Hotels-Fairfield-Inn-Suites-By-Marriott-Cape-Girardeau.h99972043.Hotel-Information) ![Town House Inn](//images.trvl-media.com/lodging/12000000/11620000/11613500/11613476/5eb3395a_y.jpg) ### Town House Inn 10/10 Excellent "It was easy and quiet and an easy check in " [](https://expedia.co.uk/Sikeston-Hotels-Town-House-Inn.h11613476.Hotel-Information) ## More cheap stays in East Cape Girardeau ![The Riverview](https://images.trvl-media.com/lodging/106000000/105090000/105081400/105081384/d68c9046_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### The Riverview 777 Main St, Cape Girardeau, MO £103 19 Oct - 20 Oct includes taxes & fees 9.2/10 Wonderful! (428 reviews) [](https://expedia.co.uk/Cape-Girardeau-Hotels-The-Riverview.h105081384.Hotel-Information) ![Pear Tree Inn Cape Girardeau Near the Medical Center](https://images.trvl-media.com/lodging/1000000/50000/40200/40113/7a520031_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Pear Tree Inn Cape Girardeau Near the Medical Center 3248 William St, Cape Girardeau, MO £59 5 Oct - 6 Oct includes taxes & fees 8.8/10 Excellent! (1,011 reviews) [](https://expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-Near-The-Medical-Center.h40113.Hotel-Information) ![Pear Tree Inn Cape Girardeau West](https://images.trvl-media.com/lodging/1000000/30000/21500/21410/3a7dec89_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Pear Tree Inn Cape Girardeau West 103 Cape West Pkwy, Cape Girardeau, MO £59 5 Oct - 6 Oct includes taxes & fees 9/10 Wonderful! (1,003 reviews) [](https://expedia.co.uk/Sikeston-Hotels-Pear-Tree-Inn-Cape-Girardeau-West.h21410.Hotel-Information) ![Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG](https://images.trvl-media.com/lodging/2000000/1280000/1278600/1278542/fe49057f_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG 3253 William Street, Cape Girardeau, MO £79 19 Oct - 20 Oct includes taxes & fees 9.4/10 Exceptional! (1,000 reviews) [](https://expedia.co.uk/Sikeston-Hotels-Holiday-Inn-Express-Hotel-Suites-Cape-Girardeau-I-55.h1278542.Hotel-Information) ![Fairfield Inn & Suites by Marriott Cape Girardeau](https://images.trvl-media.com/lodging/100000000/99980000/99972100/99972043/347bcd98_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Fairfield Inn & Suites by Marriott Cape Girardeau 433 CAPE WEST CROSSINGS, Cape Girardeau, MO £78 12 Oct - 13 Oct includes taxes & fees 9.2/10 Wonderful! (129 reviews) [](https://expedia.co.uk/Cape-Girardeau-Hotels-Fairfield-Inn-Suites-By-Marriott-Cape-Girardeau.h99972043.Hotel-Information) ![Quality Inn](https://images.trvl-media.com/lodging/1000000/860000/856000/855988/d2a0e781_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Quality Inn 2011 North Kingshighway, Cape Girardeau, MO £50 16 Oct - 17 Oct includes taxes & fees 7/10 Good! (644 reviews) [](https://expedia.co.uk/Sikeston-Hotels-Quality-Inn.h855988.Hotel-Information) ## Explore a world of travel with Expedia - Explore a world of travel with Expedia ### Accommodation near East Cape Girardeau attractions - [Hotels near Shawnee National Forest](https://expedia.co.uk/Shawnee-National-Forest-Hotels.0-l553248635944113522-0.Travel-Guide-Filter-Hotels) - [Hotels near Mississippi River](https://expedia.co.uk/Mississippi-River-Hotels.0-l6209928-0.Travel-Guide-Filter-Hotels) - [Hotels near Southeast Missouri State University](https://expedia.co.uk/Southeast-Missouri-State-University-Hotels.0-l553248621554122994-0.Travel-Guide-Filter-Hotels) ### Hotels Near East Cape Girardeau, Illinois - [Cape Girardeau Hotels](https://expedia.co.uk/Cape-Girardeau-Hotels.d820.Travel-Guide-Hotels) - [Sikeston Hotels](https://expedia.co.uk/Sikeston-Hotels.d6058766.Travel-Guide-Hotels) - [Ozarks Hotels](https://expedia.co.uk/Ozarks-Hotels.d6209951.Travel-Guide-Hotels) - [Southern Illinois Hotels](https://expedia.co.uk/Southern-Illinois-Hotels.d6233859.Travel-Guide-Hotels) - [Jackson Hotels](https://expedia.co.uk/Jackson-Hotels.d55765.Travel-Guide-Hotels) - [Cairo Hotels](https://expedia.co.uk/Cairo-Hotels.d6626.Travel-Guide-Hotels) - [Cobden Hotels](https://expedia.co.uk/Cobden-Hotels.d3000433811.Travel-Guide-Hotels) - [Anna Hotels](https://expedia.co.uk/Anna-Hotels.d6406.Travel-Guide-Hotels) - [Alto Pass Hotels](https://expedia.co.uk/Alto-Pass-Hotels.d73449.Travel-Guide-Hotels) - [Charleston Hotels](https://expedia.co.uk/Charleston-Hotels.d7182.Travel-Guide-Hotels) - [Southeast Missouri Hotels](https://expedia.co.uk/Southeast-Missouri-Hotels.d6058763.Travel-Guide-Hotels) - [Jonesboro Hotels](https://expedia.co.uk/Jonesboro-Hotels.d3000434361.Travel-Guide-Hotels) - [Scott City Hotels](https://expedia.co.uk/Scott-City-Hotels.d553248634983544376.Travel-Guide-Hotels) - [Dongola Hotels](https://expedia.co.uk/Dongola-Hotels.d3000346219.Travel-Guide-Hotels) - [Benton Hotels](https://expedia.co.uk/Benton-Hotels.d553248634983369680.Travel-Guide-Hotels) - [Central United States Hotels](https://expedia.co.uk/Central-United-States-Hotels.d6209877.Travel-Guide-Hotels) - [Altenburg Hotels](https://expedia.co.uk/Altenburg-Hotels.d553248634983289075.Travel-Guide-Hotels) - [Mounds Hotels](https://expedia.co.uk/Mounds-Hotels.d553248634983401107.Travel-Guide-Hotels) - [Tamms Hotels](https://expedia.co.uk/Tamms-Hotels.d3000346607.Travel-Guide-Hotels) - [Chaffee Hotels](https://expedia.co.uk/Chaffee-Hotels.d553248634983269107.Travel-Guide-Hotels) ### Explore more hotels - [Fairfield Inn & Suites by Marriott Cape Girardeau](https://expedia.co.uk/Cape-Girardeau-Hotels-Fairfield-Inn-Suites-By-Marriott-Cape-Girardeau.h99972043.Hotel-Information) - [Drury Inn & Suites Cape Girardeau](https://expedia.co.uk/Sikeston-Hotels-Drury-Inn-Suites-Cape-Girardeau.h40831.Hotel-Information) - [Town House Inn](https://expedia.co.uk/Sikeston-Hotels-Town-House-Inn.h11613476.Hotel-Information) - [Peaceful secluded cabin located near Horseshoe Lake](https://expedia.co.uk/Peaceful-Secluded-Cabin-Located-Near-Horseshoe-Lake.h109730068.Hotel-Information) - [Town House Inn Cape Giradreau](https://expedia.co.uk/Sikeston-Hotels-Town-House-Inn-Cape-Giradreau.h11613884.Hotel-Information) - [Cozy cabins on beautiful Horseshoe Lake](https://expedia.co.uk/Cozy-Cabins-On-Beautiful-Horseshoe-Lake.h90331191.Hotel-Information) - [NEW property! 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Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,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)