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Check prices for these dates

In two weeks
6 Nov - 8 Nov
In two months
18 Dec - 20 Dec
In three months
15 Jan - 17 Jan
In four months
12 Feb - 14 Feb

Our top choices for East Cape Girardeau holiday rentals

A living room with a TV, a fireplace, a sofa, and wall art.

1. Little Blue Cottage on Spanish

Little Blue Cottage on Spanish
Cape Girardeau
8.4 out of 10, Very good, (59 reviews)
"Great cute place. "
United States
Jeremy W.
The price is £84
includes taxes & fees
22 Oct - 23 Oct
Little Blue Cottage on Spanish
A cozy room with a wooden table and chairs, a large window, and a door with a sign.

2. Cozy cabins on beautiful Horseshoe Lake

Cozy cabins on beautiful Horseshoe Lake
Olive Branch
9.8 out of 10, Exceptional, (43 reviews)
"Super communication! . Accommodating. Nice people"
United States
JASEN
The price is £108
includes taxes & fees
20 Oct - 21 Oct
Cozy cabins on beautiful Horseshoe Lake
A small, single-story building with a wooden exterior and large windows.

3. The Rested Duck Mallard Room

The Rested Duck Mallard Room
Olive Branch
9.4 out of 10, Exceptional, (31 reviews)
"This is an excellent place to stay. With a nice lake right across the street. If i. In the are i will stay again for sure"
United States
mike b.
The price is £108
includes taxes & fees
20 Oct - 21 Oct
The Rested Duck Mallard Room
A hallway with white walls, a marble floor, and a door on the right.

4. Cozy 2-bedroom house in tranquil Cape Girardeau, close to Semo & Hospitals

Cozy 2-bedroom house in tranquil Cape Girardeau, close to Semo & Hospitals
Cape Girardeau
The price is £143
includes taxes & fees
16 Nov - 17 Nov
Cozy 2-bedroom house in tranquil Cape Girardeau, close to Semo & Hospitals
A bedroom with a bed, a bottle of J. Roget champagne, two glasses, and a plate with snacks.

5. The Cottage, Rusted Route Farms

The Cottage, Rusted Route Farms
Jackson
10.0 out of 10, Exceptional, (3 reviews)
"This Cottage was very nice and clean and well maintained. The meat tray that we ordered and the breakfast tray was beyond Fabulous!!! My husband is still talking about it. . .Rick & Renee Christman"
United States
Renee C.
The price is £154
includes taxes & fees
20 Oct - 21 Oct
The Cottage, Rusted Route Farms
Exterior

6. Purple Tiny House with Fire pit & Nature

Purple Tiny House with Fire pit & Nature
Cape Girardeau
10.0 out of 10, Exceptional, (1 review)
"First time staying in the purple house, second time staying at the property. 10/10 recommend"
United States
Shawn A.
The price is £155
includes taxes & fees
20 Oct - 21 Oct
Purple Tiny House with Fire pit & Nature
Exterior

7. Romantic Creekside Retreat | Fireplace | Deck | Pet Friendly

Romantic Creekside Retreat | Fireplace | Deck | Pet Friendly
Cape Girardeau
10.0 out of 10, Exceptional, (3 reviews)
"The house was very clean and Will kept and the whole property was well maintained. It was very comfortable and nicely decorated. The host was very responsive and helpful! Would definitely stay again and recommend."
United States
Sara C.
The price is £175
includes taxes & fees
20 Oct - 21 Oct
Romantic Creekside Retreat | Fireplace | Deck | Pet Friendly
Private kitchen

8. Enchanted Mermaid A-Frame | Creek + Fire pit | Pet Friendly

Enchanted Mermaid A-Frame | Creek + Fire pit | Pet Friendly
Cape Girardeau
The price is £179
includes taxes & fees
20 Oct - 21 Oct
Enchanted Mermaid A-Frame | Creek + Fire pit | Pet Friendly
A modern living room with a wooden ceiling, a stone fireplace, a TV mounted on the wall, and a bar area with stools.

9. The Twisted Sassafras Treehouse

The Twisted Sassafras Treehouse
Cape Girardeau
10.0 out of 10, Exceptional, (40 reviews)
"Amazing stay! Everything was perfect."
United States
Wayne F.
The price is £272
includes taxes & fees
26 Oct - 27 Oct
The Twisted Sassafras Treehouse
A serene outdoor area with a pond, surrounded by trees and a grassy lawn. There are two wooden benches facing the water.

10. Charming cottage overlooking Lake Acre

Charming cottage overlooking Lake Acre
Dongola
10.0 out of 10, Exceptional, (107 reviews)
"The cottage was clean, spacious, had 2 bathrooms (which is uncommon for small cabins). It was very well stocked with kitchen items, and the bath towels were awesome, the bed was very nice. It was peaceful and beautiful. The hostess, Suzie was easy to contact and helpful when we had a question upon checking ìn. I would recommend this place and would stay again if we are in the area!"
United States
Teresa
The price is £188
includes taxes & fees
20 Oct - 21 Oct
Charming cottage overlooking Lake Acre
Ground floor of the Euro

11. The Little Château | Woodland Escape

The Little Château | Woodland Escape
Cape Girardeau
The price is £171
includes taxes & fees
20 Oct - 21 Oct
The Little Château | Woodland Escape
A two-story house with a front porch, a small garden, and a white picket fence.

12. 3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
Cape Girardeau
8.8 out of 10, Excellent, (46 reviews)
"Will definitely book again! Great location, comfortable stay."
United States
Pynktoria !.
The price is £237
includes taxes & fees
20 Oct - 21 Oct
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
A compact kitchen with wooden cabinets and a dining area with a table and chairs.

13. Villa B offers peace and quiet with beautiful views of the countryside.

Villa B offers peace and quiet with beautiful views of the countryside.
Jackson
9.8 out of 10, Exceptional, (16 reviews)
"We were only there for 1 night for a business trip but it was perfect for our stay. Very clean and comfortable and the host was onsite to welcome us. She even gave us a tip on the best place nearby for dinner that we will be going to any time we can in the future. I would gladly stay here again for future trips."
United States
Terry H.
The price is £138
includes taxes & fees
24 Oct - 25 Oct
Villa B offers peace and quiet with beautiful views of the countryside.
A loft-style room with a wooden interior, a sofa, a table with a pumpkin decoration, and a staircase leading to an upper level.

14. Peaceful secluded cabin located near Horseshoe Lake

Peaceful secluded cabin located near Horseshoe Lake
Miller City
9.8 out of 10, Exceptional, (39 reviews)
"Great place in a beautiful location. "
United States
George B.
The price is £155
includes taxes & fees
20 Oct - 21 Oct
Peaceful secluded cabin located near Horseshoe Lake
Exterior

15. The Little Cape Lofted Cottage | Creek & Nature

The Little Cape Lofted Cottage | Creek & Nature
Cape Girardeau
9.0 out of 10, Wonderful, (2 reviews)
"It was very clean and had a good feel. It was well stocked. I appreciated the cute little ice tray in the freezer that was full. I also appreciated 4 waters in the fridge. The bed on the loft upstairs was atrocious. You can feel the springs through the mattress. The downstairs bed was good. The pillows were fantastic! I’m a pillow snob. We needed a quick place to land for a church function so I can’t say much about the outside amenities as we weren’t there much. But it was a beautifully tucked...
United States
Trisha S.
The price is £174
includes taxes & fees
20 Oct - 21 Oct
The Little Cape Lofted Cottage | Creek & Nature
A kitchen with wooden cabinets, a black refrigerator, a microwave, a stove, and a ceiling fan. There are three stools at the island.

16. Relax in the country at Countryside Villas! - Villa A

Relax in the country at Countryside Villas! - Villa A
Jackson
10.0 out of 10, Exceptional, (39 reviews)
"Great place to stay, felt like home away from home. "
United States
Brittany
The price is £138
includes taxes & fees
22 Oct - 23 Oct
Relax in the country at Countryside Villas! - Villa A
A wooden cabinet with a microwave, coffee maker, and plates.

17. Cozy and Updated Farmhouse with King Suite

Cozy and Updated Farmhouse with King Suite
Anna
10.0 out of 10, Exceptional, (27 reviews)
"Comfortable bed which is what we needed. We weren’t there long but is was everything we needed."
United States
Kathy H.
The price is £130
includes taxes & fees
27 Oct - 28 Oct
Cozy and Updated Farmhouse with King Suite
A log cabin interior with a stone fireplace, leather sofa, and a mounted deer head.

18. Gorgeous 1856 Log Cabin, Completely Renovated

Gorgeous 1856 Log Cabin, Completely Renovated
Jackson
10.0 out of 10, Exceptional, (6 reviews)
"incredible place. I was there for work, but it was a really nice relaxing area to retreat too, and also get some work done in a serene environment. It would be an incredible place for an entire family. And, a good place for friends to get together."
United States
Chandler G.
The price is £236
includes taxes & fees
20 Oct - 21 Oct
Gorgeous 1856 Log Cabin, Completely Renovated
A modern kitchen with a large island, white cabinetry, and a brick accent wall.

19. Beautifully Renovated Farmhouse in Jackson, MO

Beautifully Renovated Farmhouse in Jackson, MO
Jackson
9.4 out of 10, Exceptional, (3 reviews)
" great stay,property landscape nicely manicured, quiet and relaxing inside and outside of the the dwelling."
United States
Sandy S.
The price is £232
includes taxes & fees
26 Oct - 27 Oct
Beautifully Renovated Farmhouse in Jackson, MO
A brick building with a sign reading "1898 Guesthouse".

20. Stunning 2 bedroom in town, close to Shawnee National Forest

Stunning 2 bedroom in town, close to Shawnee National Forest
Jonesboro
10.0 out of 10, Exceptional, (15 reviews)
"Cool renovated property that keeps that old fashioned charm. Spacious living with all the amenities you need for a vacation stay."
United States
Dylan
The price is £218
includes taxes & fees
21 Oct - 22 Oct
Stunning 2 bedroom in town, close to Shawnee National Forest
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top East Cape Girardeau Hotel Reviews

Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO

10/10 Excellent
"The room was clean and the breakfast was good. It was quiet as well."
Karen 1-night trip
Posted less than an hour ago
Drury Inn & Suites Jackson MO

Find out more about East Cape Girardeau

Everything you need to know about East Cape Girardeau holiday rentals

Whether you’re excited for the perfect family holiday, a romantic getaway for two, or the ultimate city break, we’ve got the East Cape Girardeau holiday rental for you. At Expedia, you can take your pick from private holiday homes, apartments, cottages, apart-hotels, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect East Cape Girardeau holiday rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. 

East Cape Girardeau holiday rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in East Cape Girardeau. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in . 

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A East Cape Girardeau holiday rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a holiday rental with multiple bedrooms and shared living spaces to kick back in.  The selection of East Cape Girardeau holiday rentals we have selected for you start as low as £84 per night. Entering your travel dates in the search wizard you might find even better deals!

How to find incredible deals on East Cape Girardeau rentals

At Expedia, we put the best East Cape Girardeau holiday rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. 

To find some top East Cape Girardeau rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream East Cape Girardeau holiday.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around East Cape Girardeau. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. 

Frequently asked questions

Are there holiday rentals in East Cape Girardeau?

Yes, there are holiday rentals close to the most popular sights in East Cape Girardeau, or you can select a more secluded option if you're looking for a relaxing stay.

What are some of the best holiday rentals that East Cape Girardeau has to offer?

3 Bed 3 Bath Beautiful Historic District Within Walking Downtown Cape Girardeau: This holiday home rental outside of East Cape Girardeau is equipped with a BBQ, air conditioning and laundry facilities to help you feel comfortable during your stay. Kitchen amenities include a dishwasher, a fridge and a stovetop.

What’s there to see and do in East Cape Girardeau?

Explore the area and family-friendly sights such as Cape Splash Family Aquatic Center, or get out into nature at a spot like Fort D Historic Site. Century Casino & Hotel Cape Girardeau and Southeast Missouri State University are a couple of places you'll find in the wider area.

What’s a holiday rental in East Cape Girardeau like?

Holiday rentals are private properties where you can stay for a few weeks, or just a few days, in East Cape Girardeau. Holiday rentals feature extras such as patios, hot tubs and fire pits so you'll feel just like you're staying in your own home. If you're concerned about cleanliness, holiday rentals can provide a sense of seclusion away from shared hotel lifts and busy front desks while still allowing you to travel. You'll also find more space in a holiday rental than in a traditional hotel, which makes a holiday rental a popular choice for a family getaway.