Title: Top Hotels in Knox County - Compare Knox County Hotels | Expedia.co.uk [Holiday Rentals in Knox County](https://expedia.co.uk/Destinations-In-Knox-County.d553248635976432457.Holiday-Rental-Destinations)[Knox County Car Hire](https://expedia.co.uk/Destinations-In-Knox-County.d553248635976432457.Car-Hire-Destinations)[Knox County Holidays](https://expedia.co.uk/Knox-County.d553248635976432457.Holidays-City-Breaks) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find the best Knox County Hotels ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Knox County Pet friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Knox+County%2C+Missouri%2C+United+States+of+America®ionId=553248635976432457&latLong=40.128256%2C-92.148075&adults=2&startDate=2025-10-24&d1=2025-10-24&endDate=2025-10-26&d2=2025-10-26&amenities=PETS) Family friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Knox+County%2C+Missouri%2C+United+States+of+America®ionId=553248635976432457&latLong=40.128256%2C-92.148075&adults=2&startDate=2025-10-24&d1=2025-10-24&endDate=2025-10-26&d2=2025-10-26&travelerType=family_friendly) ## Check prices for these dates Tonight [10 Oct - 11 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976432457&startDate=2025-10-10&endDate=2025-10-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [11 Oct - 12 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976432457&startDate=2025-10-11&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [10 Oct - 12 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976432457&startDate=2025-10-10&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [17 Oct - 19 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976432457&startDate=2025-10-17&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Hotels Knox County ![Smart TV](https://images.trvl-media.com/lodging/112000000/111060000/111053400/111053317/5541de84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, coffee/tea maker, toaster](https://images.trvl-media.com/lodging/112000000/111060000/111053400/111053317/8ce26e88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/112000000/111060000/111053400/111053317/d961686e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111060000/111053400/111053317/038e8d64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tiny Cozy Cottage in Edina, MO Edina 10/10 Exceptional (10) "It was a great place too stay " £80 includes taxes & fees 11 Oct - 12 Oct [](https://www.expedia.co.uk/Edina-Hotels-Tiny-Cozy-Cottage-In-Edina.h111053317.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/93000000/92900000/92897900/92897834/a756355b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, books](https://images.trvl-media.com/lodging/93000000/92900000/92897900/92897834/498c7144.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/93000000/92900000/92897900/92897834/8c5a89c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, free WiFi, bed sheets](https://images.trvl-media.com/lodging/93000000/92900000/92897900/92897834/2170638b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Edina Missouri New Cabin in Rural Area Edina 10/10 Exceptional (30) "Absolutely beautiful property perfect hosts. " [](https://www.expedia.co.uk/Edina-Hotels-Edina-Missouri-New-Cabin-In-Rural-Area.h92897834.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/33000000/32670000/32666300/32666255/f6665c52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/33000000/32670000/32666300/32666255/9004b27f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/33000000/32670000/32666300/32666255/270-4043fcee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fireplace, books](https://images.trvl-media.com/lodging/33000000/32670000/32666300/32666255/8f2cae1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lost Branch Lodge. Complete interior remodel, spring 2022! Brashear 10/10 Exceptional (177) "We have come here annually for the last several years. " [](https://www.expedia.co.uk/Brashear-Hotels-Lost-Branch-Lodge-Relaxation-In-A-Quiet.h32666255.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-24&endDate=2025-10-25®ionId=553248635976432457&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Knox-County.d553248635976432457.Hotel-Destinations)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Knox-County.d553248635976432457.Hotel-Destinations) ## Top Knox County Hotel Reviews ![Super 8 by Wyndham Kirksville-University Area](//images.trvl-media.com/lodging/1000000/130000/123600/123590/adba1fe4_y.jpg) ### Super 8 by Wyndham Kirksville-University Area 10/10 Excellent "Nice " [](https://expedia.co.uk/Macon-Hotels-Country-Club-Inn-Suites.h123590.Hotel-Information) ![OYO Travelier Motel](//images.trvl-media.com/lodging/5000000/4030000/4029200/4029112/49aabdef_y.jpg) ### OYO Travelier Motel 10/10 Excellent "Everything was good." [](https://expedia.co.uk/Macon-Hotels-Travelier-Motel.h4029112.Hotel-Information) ![Depot Inn and Suites](//images.trvl-media.com/lodging/2000000/1800000/1790900/1790806/6c9e28fd_y.jpg) ### Depot Inn and Suites 10/10 Excellent "We were on the way home from a 10 day trip and decided to stop for the night. What a treasure we found! I can see people who live within hours coming for a few days just to enjoy the ambiance. The staff was great, the rooms just lovely and comfortable, the pool nice, and it had a great Mexican restaurant very close. I wish we had had more time to ride the bikes and play pool. I would have liked more comfy pillows, but it was a top 10 stay!" [](https://expedia.co.uk/La-Plata-Hotels-Depot-Inn-And-Suites.h1790806.Hotel-Information) ![New tiny home in an incredible private setting among all nature has to offer.](//images.trvl-media.com/lodging/118000000/117030000/117029100/117029091/2899d4ac_y.jpg) ### New tiny home in an incredible private setting among all nature has to offer. 10/10 Excellent "Loved this place! Can't wait to come back! " [](https://expedia.co.uk/Kirksville-Hotels-New-Tiny-Home-In-An-Incredible-Private-Setting-Among-All-Nature-Has-To-Offer.h117029091.Hotel-Information) ![Thousand Hills](//images.trvl-media.com/lodging/107000000/106800000/106792500/106792431/855824fb_y.jpg) ### Thousand Hills 10/10 Excellent "Beautiful views and cabins are decently spaced for privacy." [](https://expedia.co.uk/Kirksville-Hotels-Thousand-Hills.h106792431.Hotel-Information) ![Little Blue Cottage - Charming 1-bedroom cottage in Kirksville](//images.trvl-media.com/lodging/109000000/108400000/108390200/108390143/acd401ea_y.jpg) ### Little Blue Cottage - Charming 1-bedroom cottage in Kirksville 10/10 Excellent "A lot of old homes that are not well taken care of. " [](https://expedia.co.uk/Kirksville-Hotels-Little-Blue-Cottage-Charming-1-Bedroom-Cottage-In-Kirksville.h108390143.Hotel-Information) ![Tiny Cozy Cottage in Edina, MO](//images.trvl-media.com/lodging/112000000/111060000/111053400/111053317/5541de84_y.jpg) ### Tiny Cozy Cottage in Edina, MO 10/10 Excellent "Clean, adorable decor, personal contact with owner was very helpful." [](https://expedia.co.uk/Edina-Hotels-Tiny-Cozy-Cottage-In-Edina.h111053317.Hotel-Information) ![Americas Best Value Inn & Suites Macon at Sunset Dr](//images.trvl-media.com/lodging/1000000/30000/22300/22238/375eafcb_y.jpg) ### Americas Best Value Inn & Suites Macon at Sunset Dr 10/10 Excellent "Cleanand quiet friendly and helpful staff.." [](https://expedia.co.uk/Macon-Hotels-Americas-Best-Value-Inn-Suites-Macon-At-Sunset-Dr.h22238.Hotel-Information) ![Country Cabin In The Woods](//images.trvl-media.com/lodging/105000000/104310000/104308300/104308277/529c3996_y.jpg) ### Country Cabin In The Woods 10/10 Excellent "The cabin was a great get away from the town. Very remote and peaceful cabin. Very clean. Could have used some brighter lighting. It was difficult to play games at the kitchen table after sunset. Thank you!!!" [](https://expedia.co.uk/Kirksville-Hotels-Country-Cabin-In-The-Woods.h104308277.Hotel-Information) ## Explore a world of travel with Expedia - Explore a world of travel with Expedia ### Top cities in Knox County - [Edina Hotels](https://expedia.co.uk/Edina-Hotels.d3000444857.Travel-Guide-Hotels) - [Hurdland Hotels](https://expedia.co.uk/Hurdland-Hotels.d3000349403.Travel-Guide-Hotels) - [Newark Hotels](https://expedia.co.uk/Newark-Hotels.d553248634983173284.Travel-Guide-Hotels) - [Novelty Hotels](https://expedia.co.uk/Novelty-Hotels.d553248634983584874.Travel-Guide-Hotels) - [Knox City Hotels](https://expedia.co.uk/Knox-City-Hotels.d553248634983184107.Travel-Guide-Hotels) ### Explore more hotels - [Tiny Cozy Cottage in Edina, MO](https://expedia.co.uk/Edina-Hotels-Tiny-Cozy-Cottage-In-Edina.h111053317.Hotel-Information) - [Super 8 by Wyndham Kirksville-University Area](https://expedia.co.uk/Macon-Hotels-Country-Club-Inn-Suites.h123590.Hotel-Information) - [Depot Inn and Suites](https://expedia.co.uk/La-Plata-Hotels-Depot-Inn-And-Suites.h1790806.Hotel-Information) - [Americas Best Value Inn & Suites Macon at Sunset Dr](https://expedia.co.uk/Macon-Hotels-Americas-Best-Value-Inn-Suites-Macon-At-Sunset-Dr.h22238.Hotel-Information) [See a list of all hotels in Knox County](https://expedia.co.uk/All-Knox-County-Hotels.d553248635976432457.Travel-Guide-City-All-Hotels) ### More ways to book - [Book Hotels in Knox County on Expedia.com](https://www.expedia.com/Destinations-In-Knox-County.d553248635976432457.Hotel-Destinations) ### Expedia's Latest Trends Hotels - [Sentido Apollo Palace and Waterslides](https://expedia.co.uk/Corfu-Hotels-SENTIDO-Apollo-Palace.h34079032.Hotel-Information) - [Novotel Berlin Mitte](https://expedia.co.uk/Berlin-Hotels-Novotel-Berlin-Mitte.h877209.Hotel-Information) - [The House of Bruar hotels](https://expedia.co.uk/The-House-Of-Bruar-Hotels.0-l553248621584289328-0.Travel-Guide-Filter-Hotels) - [Hotels in Orange County](https://expedia.co.uk/Destinations-In-Orange-County.d603224.Hotel-Destinations) - [All-Inclusive Hotels in San Diego County](https://expedia.co.uk/Destinations-In-San-Diego-County-All-Inclusive-Hotel.0-0-d178304-tAllInclusiveHotel.Hotel-Filter-Destinations) - 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Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,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)