Title: Top Hotels in Knox County - Compare Knox County Hotels | Expedia.co.uk [Holiday Rentals in Knox County](https://expedia.co.uk/Destinations-In-Knox-County.d553248635976432457.Holiday-Rental-Destinations)[Knox County Car Hire](https://expedia.co.uk/Destinations-In-Knox-County.d553248635976432457.Car-Hire-Destinations)[Knox County Holidays](https://expedia.co.uk/Knox-County.d553248635976432457.Holidays-City-Breaks) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find the best Knox County Hotels - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Knox County Pool [](https://www.expedia.co.uk/Hotel-Search?destination=Knox+County%2C+Missouri%2C+United+States+of+America®ionId=553248635976432457&latLong=40.128256%2C-92.148075&adults=2&startDate=2025-12-20&d1=2025-12-20&endDate=2025-12-22&d2=2025-12-22&amenities=POOL) Family friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Knox+County%2C+Missouri%2C+United+States+of+America®ionId=553248635976432457&latLong=40.128256%2C-92.148075&adults=2&startDate=2025-12-20&d1=2025-12-20&endDate=2025-12-22&d2=2025-12-22&travelerType=family_friendly) Pet friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Knox+County%2C+Missouri%2C+United+States+of+America®ionId=553248635976432457&latLong=40.128256%2C-92.148075&adults=2&startDate=2025-12-20&d1=2025-12-20&endDate=2025-12-22&d2=2025-12-22&amenities=PETS) Cottage [](https://www.expedia.co.uk/Hotel-Search?destination=Knox+County%2C+Missouri%2C+United+States+of+America®ionId=553248635976432457&latLong=40.128256%2C-92.148075&adults=2&startDate=2025-12-20&d1=2025-12-20&endDate=2025-12-22&d2=2025-12-22&lodging=COTTAGE) ## Check prices for these dates Tonight [6 Dec - 7 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976432457&startDate=2025-12-06&endDate=2025-12-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [7 Dec - 8 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976432457&startDate=2025-12-07&endDate=2025-12-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [12 Dec - 14 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976432457&startDate=2025-12-12&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [19 Dec - 21 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248635976432457&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Hotels Knox County ![Smart TV](https://images.trvl-media.com/lodging/112000000/111060000/111053400/111053317/5541de84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111060000/111053400/111053317/038e8d64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/112000000/111060000/111053400/111053317/d961686e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, free WiFi, bed sheets](https://images.trvl-media.com/lodging/112000000/111060000/111053400/111053317/fc8a6d7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tiny Cozy Cottage in Edina, MO Edina 10/10 Exceptional (10) "Clean, adorable decor, personal contact with owner was very helpful." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mark B. £80 includes taxes & fees 8 Dec - 9 Dec [](https://www.expedia.co.uk/Edina-Hotels-Tiny-Cozy-Cottage-In-Edina.h111053317.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/93000000/92900000/92897900/92897834/a756355b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, free WiFi, bed sheets](https://images.trvl-media.com/lodging/93000000/92900000/92897900/92897834/2170638b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/93000000/92900000/92897900/92897834/8c5a89c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/93000000/92900000/92897900/92897834/00565a62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Edina Missouri New Cabin in Rural Area Edina 10/10 Exceptional (32) "Absolutely beautiful property perfect hosts. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Candace B. [](https://www.expedia.co.uk/Edina-Hotels-Edina-Missouri-New-Cabin-In-Rural-Area.h92897834.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/33000000/32670000/32666300/32666255/f6665c52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/33000000/32670000/32666300/32666255/270-4043fcee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fireplace, books](https://images.trvl-media.com/lodging/33000000/32670000/32666300/32666255/8f2cae1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/33000000/32670000/32666300/32666255/9004b27f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lost Branch Lodge. Complete interior remodel, spring 2022! Brashear 10/10 Exceptional (178) "A wonderful family oriented place, perfect for our family from Illinois, Kansas and Ohio to enjoy time together!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) richard w. [](https://www.expedia.co.uk/Brashear-Hotels-Lost-Branch-Lodge-Relaxation-In-A-Quiet.h32666255.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-12-20&endDate=2025-12-21®ionId=553248635976432457&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Knox-County.d553248635976432457.Hotel-Destinations)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Knox-County.d553248635976432457.Hotel-Destinations) ## Top Knox County Hotel Reviews ![Depot Inn and Suites](https://images.trvl-media.com/lodging/2000000/1800000/1790900/1790806/6c9e28fd_y.jpg) ### Depot Inn and Suites 10/10 Excellent "This is not your run-of-the-mill motel. The place is immaculate and the decor feels luxurious. The rooms feel more like a spare bedroom in a million dollar home with the lush carpet, crown moulding, arches, etc. Looks and smells fresh and clean throughout. Particularly noteworthy is the railroad/train motif with museum-like displays lining the hallways. A continental breakfast is usually predictably skimpy and boring, but this was the nicest I have seen with a nice selection of fresh fruit, hard boiled eggs, bagels, plus all the other items you would expect including waffles. It was a bit pricey for us, because we usually get the cheapest motel with acceptable ratings, but this was so nice and comfortable that I will gladly spring for the extra money to have this experience again. NO REGRETS!!! " [](https://expedia.co.uk/La-Plata-Hotels-Depot-Inn-And-Suites.h1790806.Hotel-Information) ![Simple Rewards Inn Shelbina](https://images.trvl-media.com/lodging/2000000/1170000/1162500/1162434/8e4c4277_y.jpg) ### Simple Rewards Inn Shelbina 10/10 Excellent "Was a lot nicer than I was expecting " [](https://expedia.co.uk/Macon-Hotels-Simple-Rewards-Inn-Shelbina.h1162434.Hotel-Information) ![Super 8 by Wyndham Kirksville-University Area](https://images.trvl-media.com/lodging/1000000/130000/123600/123590/adba1fe4_y.jpg) ### Super 8 by Wyndham Kirksville-University Area 10/10 Excellent "Remodel" [](https://expedia.co.uk/Macon-Hotels-Country-Club-Inn-Suites.h123590.Hotel-Information) ![OYO Travelier Motel](https://images.trvl-media.com/lodging/5000000/4030000/4029200/4029112/49aabdef_y.jpg) ### OYO Travelier Motel 10/10 Excellent "Room was great service was awesome " [](https://expedia.co.uk/Macon-Hotels-Travelier-Motel.h4029112.Hotel-Information) ![Unwind on Vine ](https://images.trvl-media.com/lodging/107000000/106730000/106726000/106725956/ee78f726_y.jpg) ### Unwind on Vine 10/10 Excellent "We were there for a very short stay for the horse sale but the location and ease of stay was excellent would stay again hopefully not as short the next time!" [](https://expedia.co.uk/Macon-Hotels-Unwind-On-Vine.h106725956.Hotel-Information) ![Americas Best Value Inn & Suites Macon at Sunset Dr](https://images.trvl-media.com/lodging/1000000/30000/22300/22238/375eafcb_y.jpg) ### Americas Best Value Inn & Suites Macon at Sunset Dr 10/10 Excellent "Very clean, comfortable, quiet. I will definitely stay again " [](https://expedia.co.uk/Macon-Hotels-Americas-Best-Value-Inn-Suites-Macon-At-Sunset-Dr.h22238.Hotel-Information) ![Tiny Cozy Cottage in Edina, MO](https://images.trvl-media.com/lodging/112000000/111060000/111053400/111053317/5541de84_y.jpg) ### Tiny Cozy Cottage in Edina, MO 10/10 Excellent "Exactly what we needed for our hunting trip!" [](https://expedia.co.uk/Edina-Hotels-Tiny-Cozy-Cottage-In-Edina.h111053317.Hotel-Information) ![Spacious 12-bedroom 10-Bath Cedar accented lodge in Picturesque Macon Missouri](https://images.trvl-media.com/lodging/104000000/103100000/103095500/103095473/75aced48_y.jpg) ### Spacious 12-bedroom 10-Bath Cedar accented lodge in Picturesque Macon Missouri 10/10 Excellent "The rooms were very clean and comfortable. It was very hot and humid outside, but the AC and ceiling fans kept up well. The host answered questions quickly. We had rain (and lots of it) every day but our last, but had a good time anyway; making use of the game room, large dining areas for other games, and the pond for fishing and kayaking between storms. The kitchen was well equipped and bedding and towels were very nice." [](https://expedia.co.uk/Macon-Hotels-Spacious-12-Bedroom-10-Bath-Cedar-Accented-Lodge-In-Picturesque-Macon-Missouri.h103095473.Hotel-Information) ![Country Cabin In The Woods](https://images.trvl-media.com/lodging/105000000/104310000/104308300/104308277/529c3996_y.jpg) ### Country Cabin In The Woods 10/10 Excellent "The cabin was a great get away from the town. Very remote and peaceful cabin. Very clean. Could have used some brighter lighting. It was difficult to play games at the kitchen table after sunset. Thank you!!!" [](https://expedia.co.uk/Kirksville-Hotels-Country-Cabin-In-The-Woods.h104308277.Hotel-Information) ## Explore a world of travel with Expedia - Explore a world of travel with Expedia ### Top cities in Knox County - [Edina Hotels ](https://expedia.co.uk/Edina-Hotels.d3000444857.Travel-Guide-Hotels) - [Knox City Hotels ](https://expedia.co.uk/Knox-City-Hotels.d553248634983184107.Travel-Guide-Hotels) - [Novelty Hotels ](https://expedia.co.uk/Novelty-Hotels.d553248634983584874.Travel-Guide-Hotels) - [Hurdland Hotels ](https://expedia.co.uk/Hurdland-Hotels.d3000349403.Travel-Guide-Hotels) - [Newark Hotels ](https://expedia.co.uk/Newark-Hotels.d553248634983173284.Travel-Guide-Hotels) ### Explore more hotels - [Tiny Cozy Cottage in Edina, MO ](https://expedia.co.uk/Edina-Hotels-Tiny-Cozy-Cottage-In-Edina.h111053317.Hotel-Information) - [Super 8 by Wyndham Kirksville-University Area ](https://expedia.co.uk/Macon-Hotels-Country-Club-Inn-Suites.h123590.Hotel-Information) - [Depot Inn and Suites ](https://expedia.co.uk/La-Plata-Hotels-Depot-Inn-And-Suites.h1790806.Hotel-Information) - [Americas Best Value Inn & Suites Macon at Sunset Dr ](https://expedia.co.uk/Macon-Hotels-Americas-Best-Value-Inn-Suites-Macon-At-Sunset-Dr.h22238.Hotel-Information) [See a list of all hotels in Knox County](https://expedia.co.uk/All-Knox-County-Hotels.d553248635976432457.Travel-Guide-City-All-Hotels) ### More ways to book - [Book Hotels in Knox County on Expedia.com ](https://www.expedia.com/Destinations-In-Knox-County.d553248635976432457.Hotel-Destinations) ### Expedia's Latest Trends Hotels - [Sentido Apollo Palace and Waterslides](https://expedia.co.uk/Corfu-Hotels-SENTIDO-Apollo-Palace.h34079032.Hotel-Information) - [Novotel Berlin Mitte](https://expedia.co.uk/Berlin-Hotels-Novotel-Berlin-Mitte.h877209.Hotel-Information) - [The House of Bruar hotels](https://expedia.co.uk/The-House-Of-Bruar-Hotels.0-l553248621584289328-0.Travel-Guide-Filter-Hotels) - [Hotels in Orange County](https://expedia.co.uk/Destinations-In-Orange-County.d603224.Hotel-Destinations) - [All-Inclusive Hotels in San Diego County](https://expedia.co.uk/Destinations-In-San-Diego-County-All-Inclusive-Hotel.0-0-d178304-tAllInclusiveHotel.Hotel-Filter-Destinations) - 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