Title: Holiday Rentals Colon from £57: Find Short-Term Rentals & Holiday Accommodations | Expedia.co.uk [Hotels in Colon](https://expedia.co.uk/Colon-Hotels.d601867.Travel-Guide-Hotels)[Flights to Colon](https://expedia.co.uk/Cheap-Flights-To-Colon.d601867.Travel-Guide-Flights)[Things to do in Colon](https://expedia.co.uk/Things-To-Do-In-Colon.d601867.Travel-Guide-Activities)[Colon Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Colon.d601867.Car-Hire-Guide)[Colon Holidays](https://expedia.co.uk/Colon.d601867.Holidays-City-Breaks) ![Adobe](https://images.trvl-media.com/place/601867/943091b0-9dea-43c5-9bcc-64801cfef8b7.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/601867/943091b0-9dea-43c5-9bcc-64801cfef8b7.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates In two weeks [20 Feb - 22 Feb](https://www.expedia.co.uk/Hotel-Search?regionId=601867&startDate=2026-02-20&endDate=2026-02-22&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [3 Apr - 5 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=601867&startDate=2026-04-03&endDate=2026-04-05&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [1 May - 3 May](https://www.expedia.co.uk/Hotel-Search?regionId=601867&startDate=2026-05-01&endDate=2026-05-03&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [29 May - 31 May](https://www.expedia.co.uk/Hotel-Search?regionId=601867&startDate=2026-05-29&endDate=2026-05-31&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Colon holiday rentals ![50-inch LED TV with satellite channels](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/81757b88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![50-inch LED TV with satellite channels](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/dc088c7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/bba49e63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining room](https://images.trvl-media.com/lodging/105000000/104460000/104456900/104456900/dbfbf214.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Arcadia Condo Suites [](https://www.expedia.co.uk/Panama-City-Hotels-Arcadia-Condo-Suites.h104456900.Hotel-Information) Costa del Este 9.4/10 Exceptional (204 reviews) "Really loved this place" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alejandra £101 includes taxes & fees 2 Mar - 3 Mar [](https://www.expedia.co.uk/Panama-City-Hotels-Arcadia-Condo-Suites.h104456900.Hotel-Information) ![Private beach](https://images.trvl-media.com/lodging/122000000/121190000/121188200/121188154/30ff294e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Room, Courtyard View | Blackout curtains, free WiFi, bed sheets](https://images.trvl-media.com/lodging/122000000/121190000/121188200/121188154/070ae157.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/122000000/121190000/121188200/121188154/e0ea3259.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/122000000/121190000/121188200/121188154/87c35f6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Habitación con entrada Privada en Playa Dorada + Kitchenette y baño. [](https://www.expedia.co.uk/Vacamonte-Hotels-Habitacion-Privada-En-Playa-Dorada.h121188154.Hotel-Information) Vacamonte 10/10 Exceptional (2 reviews) "Really recommended! Omar is a superhost, very helpfull and lovely! Good facilities and there is a swimmingpool and a nice little beach." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cynthia £27 includes taxes & fees 9 Feb - 10 Feb [](https://www.expedia.co.uk/Vacamonte-Hotels-Habitacion-Privada-En-Playa-Dorada.h121188154.Hotel-Information) ![Apartment, 3 Bedrooms | Living area | 32-inch Smart TV with digital channels, TV, Netflix](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/9e5233d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 3 Bedrooms | Television](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/e5394f26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms | Street view](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/cc8558b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/89000000/88680000/88675400/88675323/6445192b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Boutique Apartments Panamá Coco del Mar [](https://www.expedia.co.uk/Panama-City-Hotels-Boutique-Apartments-Panama-Coco-Del-Mar.h88675323.Hotel-Information) San Francisco 7.4/10 Good (168 reviews) "Clean room good place to stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gideon £162 includes taxes & fees 9 Feb - 10 Feb [](https://www.expedia.co.uk/Panama-City-Hotels-Boutique-Apartments-Panama-Coco-Del-Mar.h88675323.Hotel-Information) ![Apartment | Living area](https://images.trvl-media.com/lodging/114000000/113060000/113058500/113058427/c0e07415.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | Living area](https://images.trvl-media.com/lodging/114000000/113060000/113058500/113058427/2f0279c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | Living area](https://images.trvl-media.com/lodging/114000000/113060000/113058500/113058427/601ad506.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | Living area](https://images.trvl-media.com/lodging/114000000/113060000/113058500/113058427/4d9b3d57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Centriqo by Wynwood house [](https://www.expedia.co.uk/Veracruz-Hotels-Centriqo-By-Wynwood-House.h113058427.Hotel-Information) Veracruz £128 includes taxes & fees 1 Mar - 2 Mar [](https://www.expedia.co.uk/Veracruz-Hotels-Centriqo-By-Wynwood-House.h113058427.Hotel-Information) ![Comfort Suite, 1 Queen Bed with Sofa bed | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/123000000/122150000/122140800/122140766/bbe5d86c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![50-inch Smart TV with digital channels](https://images.trvl-media.com/lodging/123000000/122150000/122140800/122140766/2462f537.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Suite | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/123000000/122150000/122140800/122140766/9f96d68a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave, coffee/tea maker, cookware/dishes/utensils](https://images.trvl-media.com/lodging/123000000/122150000/122140800/122140766/6bfa829b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Palma Aparta Suite [](https://www.expedia.co.uk/Panama-City-Hotels-La-Palma-Aparta-Suite.h122140766.Hotel-Information) Amador 7.6/10 Good (5 reviews) "All ways clean and ready to used ,no buddy " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alberto £57 includes taxes & fees 9 Feb - 10 Feb [](https://www.expedia.co.uk/Panama-City-Hotels-La-Palma-Aparta-Suite.h122140766.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/5000000/4810000/4801200/4801186/24a7280d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/5000000/4810000/4801200/4801186/765b1a36.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/5000000/4810000/4801200/4801186/2370102e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio, 2 Double Beds, Non Smoking, Connecting Rooms | Premium bedding, in-room safe, individually decorated](https://images.trvl-media.com/lodging/5000000/4810000/4801200/4801186/da2b9bed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Las Clementinas [](https://www.expedia.co.uk/Panama-City-Hotels-Las-Clementinas.h4801186.Hotel-Information) Casco Viejo 9.4/10 Exceptional (179 reviews) "Fabulous room and wonderful people that work there. " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Leah £111 includes taxes & fees 10 Mar - 11 Mar [](https://www.expedia.co.uk/Panama-City-Hotels-Las-Clementinas.h4801186.Hotel-Information) ![Apartment | 2 bedrooms](https://images.trvl-media.com/lodging/124000000/123400000/123391300/123391239/3d522a7a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | 2 bedrooms](https://images.trvl-media.com/lodging/124000000/123400000/123391300/123391239/b1095926.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | 2 bedrooms](https://images.trvl-media.com/lodging/124000000/123400000/123391300/123391239/7c14eac8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | 2 bedrooms](https://images.trvl-media.com/lodging/124000000/123400000/123391300/123391239/a729fcb9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spacious 2BR w Terrace Lounge [](https://www.expedia.co.uk/Panama-City-Hotels-Spacious-2BR-W-Terrace-Lounge.h123391239.Hotel-Information) San Francisco £211 includes taxes & fees 4 Mar - 5 Mar [](https://www.expedia.co.uk/Panama-City-Hotels-Spacious-2BR-W-Terrace-Lounge.h123391239.Hotel-Information) ![Apartment, 3 Bedrooms (4B) | Living area | 32-inch Smart TV with digital channels](https://images.trvl-media.com/lodging/101000000/100640000/100638400/100638302/edb72763.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3B) | Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/101000000/100640000/100638400/100638302/3372238d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (1C) | Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/101000000/100640000/100638400/100638302/dc6d18df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (2C) | Balcony](https://images.trvl-media.com/lodging/101000000/100640000/100638400/100638302/273fe814.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Donovan By Wynwood House [](https://www.expedia.co.uk/Panama-City-Hotels-Donovan-By-Wynwood-House.h100638302.Hotel-Information) Casco Viejo 8.4/10 Very good (48 reviews) "The room was an apartment. Loud bar across the street but I loved it. Had a balcony for people watching. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andrew £85 includes taxes & fees 9 Feb - 10 Feb [](https://www.expedia.co.uk/Panama-City-Hotels-Donovan-By-Wynwood-House.h100638302.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/126000000/125270000/125266400/125266330/94d2f2bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment, City View | Interior](https://images.trvl-media.com/lodging/126000000/125270000/125266400/125266330/600a3940.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![15 outdoor pools](https://images.trvl-media.com/lodging/126000000/125270000/125266400/125266330/bee413e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment, City View | Private kitchen](https://images.trvl-media.com/lodging/126000000/125270000/125266400/125266330/ac3f0393.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Luxury Apartment Piso 35 with City View [](https://www.expedia.co.uk/Panama-City-Hotels-Luxury-Apartment-Piso-35-With-City-View.h125266330.Hotel-Information) Bella Vista £58 includes taxes & fees 12 Feb - 13 Feb [](https://www.expedia.co.uk/Panama-City-Hotels-Luxury-Apartment-Piso-35-With-City-View.h125266330.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/10000000/9680000/9675200/9675133/1012405e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sun deck](https://images.trvl-media.com/lodging/10000000/9680000/9675200/9675133/03c049bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Apartment | View from room](https://images.trvl-media.com/lodging/10000000/9680000/9675200/9675133/1b369fc4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Suite, 2 Double Beds | Living area | Flat-screen TV](https://images.trvl-media.com/lodging/10000000/9680000/9675200/9675133/871ef81e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Torres de Alba Hotel & Suites [](https://www.expedia.co.uk/Panama-City-Hotels-Torres-De-Alba-Hotel-Suites.h9675133.Hotel-Information) Bella Vista 8.8/10 Excellent (509 reviews) "Excellent place, friendly staff, great breakfast and many shops close by. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Raymond [](https://www.expedia.co.uk/Panama-City-Hotels-Torres-De-Alba-Hotel-Suites.h9675133.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/113000000/112900000/112897700/112897674/db0d74a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/113000000/112900000/112897700/112897674/6418e132.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/113000000/112900000/112897700/112897674/961aa914.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/113000000/112900000/112897700/112897674/4ff14cec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Panama View House – A Hilltop Retreat with Stunning Canal Views [](https://www.expedia.co.uk/Panama-City-Hotels-Panama-View-House-A-Hilltop-Retreat-With-Stunning-Canal-Views.h112897674.Hotel-Information) Panama City £73 includes taxes & fees 9 Feb - 10 Feb [](https://www.expedia.co.uk/Panama-City-Hotels-Panama-View-House-A-Hilltop-Retreat-With-Stunning-Canal-Views.h112897674.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/123000000/122130000/122120100/122120019/6dbcedff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Studio, Sea View | Minibar, free WiFi](https://images.trvl-media.com/lodging/123000000/122130000/122120100/122120019/9e72b36d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/123000000/122130000/122120100/122120019/fb6b983e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Studio, Sea View | Balcony view](https://images.trvl-media.com/lodging/123000000/122130000/122120100/122120019/cf68e67c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Studio Apartment with Ocean View [](https://www.expedia.co.uk/Panama-City-Hotels-Studio-Apartment-With-Ocean-View.h122120019.Hotel-Information) Calidonia 8.0/10 Very good (2 reviews) "It was similar to a hotel room, but a little smaller.. the bed is big enough for just one person and check in was the most difficult thing he had to wait outside in the rain and download apps" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gwendolyn £53 includes taxes & fees 17 Feb - 18 Feb [](https://www.expedia.co.uk/Panama-City-Hotels-Studio-Apartment-With-Ocean-View.h122120019.Hotel-Information) ![Outdoor pool, open 8:00 AM to 10:00 PM, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/w846h1318x0y4-5df5c378.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (705) | Balcony](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/ba5a7e97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Apartment | Balcony](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/ee1ac3ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Apartment | Living area | Smart TV](https://images.trvl-media.com/lodging/103000000/102810000/102803600/102803573/03e26607.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Casco View Apartments [](https://www.expedia.co.uk/Panama-City-Hotels-Casco-View-Apartments.h102803573.Hotel-Information) Santa Ana 9.0/10 Wonderful (68 reviews) "We live this property and stay here whenever we are in town." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) chris [](https://www.expedia.co.uk/Panama-City-Hotels-Casco-View-Apartments.h102803573.Hotel-Information) ![Outdoor pool, free pool cabanas, pool loungers](https://images.trvl-media.com/lodging/84000000/83070000/83067600/83067546/a1255d52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Apartment | Private kitchen | Full-sized fridge, microwave, oven, espresso maker](https://images.trvl-media.com/lodging/84000000/83070000/83067600/83067546/6e3eaaf4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Luxury Apartment | View from room](https://images.trvl-media.com/lodging/84000000/83070000/83067600/83067546/3a0adaf2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exclusive Apartment | Living area | 65-inch Smart TV with digital channels, TV](https://images.trvl-media.com/lodging/84000000/83070000/83067600/83067546/9a282904.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Yoo Panama & Arts Tower [](https://www.expedia.co.uk/Panama-City-Hotels-Apto-35G-Vista-A-La-Ciudad.h83067546.Hotel-Information) Bella Vista 9.6/10 Exceptional (66 reviews) "Ron was amazing and so was the property!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John [](https://www.expedia.co.uk/Panama-City-Hotels-Apto-35G-Vista-A-La-Ciudad.h83067546.Hotel-Information) ![Apartment (14D) | Dining room](https://images.trvl-media.com/lodging/118000000/117470000/117462500/117462452/2a0412bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | Living area](https://images.trvl-media.com/lodging/118000000/117470000/117462500/117462452/b89161f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (14D) | Soundproofing, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/118000000/117470000/117462500/117462452/422dd5ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (5E) | Living area](https://images.trvl-media.com/lodging/118000000/117470000/117462500/117462452/e5dc9f9a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Mini Design By Wynwood House [](https://www.expedia.co.uk/Panama-City-Hotels-Mini-Design-By-Wynwood-House.h117462452.Hotel-Information) Bella Vista £128 includes taxes & fees 9 Feb - 10 Feb [](https://www.expedia.co.uk/Panama-City-Hotels-Mini-Design-By-Wynwood-House.h117462452.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/115000000/114940000/114936500/114936429/b4a0c18f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | Living area | Smart TV](https://images.trvl-media.com/lodging/115000000/114940000/114936500/114936429/adb5e592.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/115000000/114940000/114936500/114936429/13fd4992.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort Apartment | 1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/115000000/114940000/114936500/114936429/e60fdc50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Sands by Wynwood House [](https://www.expedia.co.uk/Panama-City-Hotels-The-Sands-By-Wynwood-House.h114936429.Hotel-Information) Calidonia £120 includes taxes & fees 22 Feb - 23 Feb [](https://www.expedia.co.uk/Panama-City-Hotels-The-Sands-By-Wynwood-House.h114936429.Hotel-Information) ![Apartment | 2 bedrooms](https://images.trvl-media.com/lodging/124000000/123400000/123391300/123391242/9f6bde45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | 2 bedrooms](https://images.trvl-media.com/lodging/124000000/123400000/123391300/123391242/cf36effb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | 2 bedrooms](https://images.trvl-media.com/lodging/124000000/123400000/123391300/123391242/bfa00ef4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment | 2 bedrooms](https://images.trvl-media.com/lodging/124000000/123400000/123391300/123391242/046bf4b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfortable 2BR City Apartment [](https://www.expedia.co.uk/Panama-City-Hotels-Comfortable-2BR-City-Apartment.h123391242.Hotel-Information) San Francisco £143 includes taxes & fees 11 Feb - 12 Feb [](https://www.expedia.co.uk/Panama-City-Hotels-Comfortable-2BR-City-Apartment.h123391242.Hotel-Information) ![Apartment (20) | Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/101000000/100580000/100572500/100572489/dacdb94e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/101000000/100580000/100572500/100572489/7977bbcc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (05) | Living area | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/101000000/100580000/100572500/100572489/679f386c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/101000000/100580000/100572500/100572489/6c701342.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Manzana by Wynwood House [](https://www.expedia.co.uk/Panama-City-Hotels-La-Manzana-By-Wynwood-House.h100572489.Hotel-Information) Santa Ana 7.2/10 Good (15 reviews) "Great hotel. Very close to Casco viejo" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) LUCILA £73 includes taxes & fees 9 Feb - 10 Feb [](https://www.expedia.co.uk/Panama-City-Hotels-La-Manzana-By-Wynwood-House.h100572489.Hotel-Information) ![An infinity pool](https://images.trvl-media.com/lodging/79000000/78610000/78605500/78605497/172b71e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/79000000/78610000/78605500/78605497/cffde6ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/79000000/78610000/78605500/78605497/593a0532.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/79000000/78610000/78605500/78605497/e0893bc8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Beutiful Apartment, High Speed Internet, Excellent Location [](https://www.expedia.co.uk/Panama-City-Hotels-Beutiful-Apartment.h78605497.Hotel-Information) San Francisco 8.8/10 Excellent (14 reviews) "It could use a few lamps especially in the bedroom, some pictures on the walls. The curtains in the smaller bedroom didn’t close on the right side. It’s a bit run down for the price. The location is ok. It is in a neighborhood so must take a taxi. That was ok as taxis are everywhere. The view of the water is great as it has almost wrap around windows in the living/ social area." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Teri £108 includes taxes & fees 3 Mar - 4 Mar [](https://www.expedia.co.uk/Panama-City-Hotels-Beutiful-Apartment.h78605497.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/b12b577d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (17B) | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/4bc61653.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/2fdde3f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment, 2 Bedrooms (10C) | Living area | 32-inch Smart TV with digital channels, TV](https://images.trvl-media.com/lodging/92000000/91500000/91495500/91495486/ea03f013.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Boutique Apartments Atlapa [](https://www.expedia.co.uk/Panama-City-Hotels-Boutique-Apartments-Atlapa.h91495486.Hotel-Information) San Francisco 8.0/10 Very good (30 reviews) "I had an excellent stay here ! It was a very amazing the host is an amazing person thank you for making My stay great❤️" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shamia [](https://www.expedia.co.uk/Panama-City-Hotels-Boutique-Apartments-Atlapa.h91495486.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-02-22&endDate=2026-02-23®ionId=601867&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ## Find holiday rentals that suit your style Apartments [](https://www.expedia.co.uk/Hotel-Search?destination=Colon%2C+Col%C3%B3n%2C+Panama®ionId=601867&latLong=9.359296%2C-79.899863&adults=2&startDate=2026-05-09&d1=2026-05-09&endDate=2026-05-12&d2=2026-05-12&lodging=APARTMENT) Aparthotels [](https://www.expedia.co.uk/Hotel-Search?destination=Colon%2C+Col%C3%B3n%2C+Panama®ionId=601867&latLong=9.359296%2C-79.899863&adults=2&startDate=2026-05-09&d1=2026-05-09&endDate=2026-05-12&d2=2026-05-12&lodging=APART_HOTEL) Villas [](https://www.expedia.co.uk/Hotel-Search?destination=Colon%2C+Col%C3%B3n%2C+Panama®ionId=601867&latLong=9.359296%2C-79.899863&adults=2&startDate=2026-05-09&d1=2026-05-09&endDate=2026-05-12&d2=2026-05-12&lodging=VILLA) Private holiday homes [](https://www.expedia.co.uk/Hotel-Search?destination=Colon%2C+Col%C3%B3n%2C+Panama®ionId=601867&latLong=9.359296%2C-79.899863&adults=2&startDate=2026-05-09&d1=2026-05-09&endDate=2026-05-12&d2=2026-05-12&lodging=VACATION_HOME) Condos [](https://www.expedia.co.uk/Hotel-Search?destination=Colon%2C+Col%C3%B3n%2C+Panama®ionId=601867&latLong=9.359296%2C-79.899863&adults=2&startDate=2026-05-09&d1=2026-05-09&endDate=2026-05-12&d2=2026-05-12&lodging=CONDO) Cabins [](https://www.expedia.co.uk/Hotel-Search?destination=Colon%2C+Col%C3%B3n%2C+Panama®ionId=601867&latLong=9.359296%2C-79.899863&adults=2&startDate=2026-05-09&d1=2026-05-09&endDate=2026-05-12&d2=2026-05-12&lodging=CABIN) Cottages [](https://www.expedia.co.uk/Hotel-Search?destination=Colon%2C+Col%C3%B3n%2C+Panama®ionId=601867&latLong=9.359296%2C-79.899863&adults=2&startDate=2026-05-09&d1=2026-05-09&endDate=2026-05-12&d2=2026-05-12&lodging=COTTAGE) Houseboats [](https://www.expedia.co.uk/Hotel-Search?destination=Colon%2C+Col%C3%B3n%2C+Panama®ionId=601867&latLong=9.359296%2C-79.899863&adults=2&startDate=2026-05-09&d1=2026-05-09&endDate=2026-05-12&d2=2026-05-12&lodging=HOUSE_BOAT) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FColon-Holiday-Rentals.d601867.Travel-Guide-HolidayRentals)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FColon-Holiday-Rentals.d601867.Travel-Guide-HolidayRentals) ## Top Colon Hotel Reviews ![Hotel Ojos del Rio](https://images.trvl-media.com/lodging/11000000/10540000/10538500/10538417/4e16d91f_y.jpg) ### Hotel Ojos del Rio 10/10 Excellent "The staff, the food and the room and all. " [](https://expedia.co.uk/Panama-City-Hotels-Hotel-Ojos-Del-Rio.h10538417.Hotel-Information) ![Decapolis Hotel Panama City](https://images.trvl-media.com/lodging/2000000/1090000/1082800/1082793/067e7d25_y.jpg) ### Decapolis Hotel Panama City 10/10 Excellent "Good " [](https://expedia.co.uk/Panama-City-Hotels-Decapolis-Hotel-Panama-City.h1082793.Hotel-Information) ![The Executive Hotel](https://images.trvl-media.com/lodging/1000000/530000/522100/522086/493046b7_y.jpg) ### The Executive Hotel 10/10 Excellent "Staff was great, rooms were ok and clean. Breakfast was good, coffee fresh and hot at anytime so overall excellent stay. Did advertise an airport shuttle which was not available, but taxis @ 30 were available. " [](https://expedia.co.uk/Panama-City-Hotels-The-Executive-Hotel.h522086.Hotel-Information) ![Hyatt Regency Panama City](https://images.trvl-media.com/lodging/112000000/111850000/111843300/111843270/w3837h2557x3y3-241f7e7d_y.jpg) ### Hyatt Regency Panama City 10/10 Excellent "Loved everything about this hotel! CLEAN and NEW, beautiful hotel. LOVED the breakfast, loved that they accommodated to gluten free and dairy free options. Staff was nice and helpful too! " [](https://expedia.co.uk/Panama-City-Hotels-Hyatt-Regency-Panama-City.h111843270.Hotel-Information) ![Waymore Hotel Spa & Casino](https://images.trvl-media.com/lodging/97000000/96830000/96825200/96825193/75048cd3_y.jpg) ### Waymore Hotel Spa & Casino 10/10 Excellent "we got a nice upgrade. room was great. " [](https://expedia.co.uk/Panama-City-Hotels-Waymore-Hotel-Spa-Casino.h96825193.Hotel-Information) ![Marriott Panama Hotel](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/b61be540_y.jpg) ### Marriott Panama Hotel 10/10 Excellent "The room was clean, staff were nice, service was excellent! Definitely recommend " [](https://expedia.co.uk/Panama-City-Hotels-Marriott-Panama-Hotel.h6099287.Hotel-Information) ![Courtyard by Marriott Panama Multiplaza Mall](https://images.trvl-media.com/lodging/2000000/1150000/1145700/1145666/68ce59ee_y.jpg) ### Courtyard by Marriott Panama Multiplaza Mall 10/10 Excellent "Yes the room was very clean and spotless " [](https://expedia.co.uk/Panama-City-Hotels-Courtyard-By-Marriott-Panama-Multiplaza-Mall.h1145666.Hotel-Information) ![Gamboa Rainforest Reserve](https://images.trvl-media.com/lodging/1000000/440000/438200/438135/0d6dbc5b_y.jpg) ### Gamboa Rainforest Reserve 10/10 Excellent "Unique property with beautiful nature surrounding it. Staff are attentive and friendly and the Hotel has access to a lot of very unique activities. Good food as well." [](https://expedia.co.uk/Gamboa-Hotels-Gamboa-Rainforest-Reserve.h438135.Hotel-Information) ![Las Americas Golden Tower Panama](https://images.trvl-media.com/lodging/10000000/9680000/9675300/9675263/83f7ceed_y.jpg) ### Las Americas Golden Tower Panama 10/10 Excellent "Great buffet, good fitness centre. Quiet room with a great view" [](https://expedia.co.uk/Panama-City-Hotels-Las-Americas-Golden-Tower-Panama.h9675263.Hotel-Information) ## Find out more about Colon **Everything you need to know about** **Colon** **holiday rentals** Whether you’re excited for the perfect family holiday, a romantic getaway for two, or the ultimate city break, we’ve got the Colon holiday rental for you. At Expedia, you can take your pick from private holiday homes, [apartments](https://www.expedia.co.uk/aa/Apartments), cottages, [apart-hotels](https://www.expedia.co.uk/aa/ApartHotels), cabins, [villas](https://www.expedia.co.uk/aa/Villas)... The list goes on, and on… and on! There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Colon holiday rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. **Colon holiday rentals: An excellent choice for every season** Whenever you want to travel, a warm welcome awaits you in Colon. If you’re looking for a little peace, consider booking during the quieter months, such as . For more hustle and bustle, you may prefer to visit in . Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Colon holiday rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a holiday rental with multiple bedrooms and shared living spaces to kick back in. The selection of Colon holiday rentals we have selected for you start as low as £57 per night. Entering your travel dates in the search wizard you might find even better deals! **How to find incredible deals on Colon rentals** At Expedia, we put the best Colon holiday rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. To find some top Colon rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Colon holiday. If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Colon. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. ## Explore a world of travel with Expedia - Trending destinations on Expedia.co.uk ### Trending destinations on Expedia.co.uk - [Holiday Rentals in the Cotswold ](https://www.expedia.co.uk/lp/b/vr/cotswold) - [Holiday Rentals in Lake District ](https://www.expedia.co.uk/lp/b/vr/lake-district) - [Devon Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Devon.d6046196.Holiday-Rental-Destinations) - [Norfolk Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Norfolk.d6046223.Holiday-Rental-Destinations) - [Bedfordshire Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Bedfordshire.d6046189.Holiday-Rental-Destinations) - [Dorset Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Dorset.d6046198.Holiday-Rental-Destinations) - [Northumberland Holiday Rentals ](https://www.expedia.com/Destinations-In-Northumberland.d6046225.Vacation-Rental-Destinations) - [Herefordshire Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Herefordshire.d6046203.Holiday-Rental-Destinations) - [Essex Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Essex.d6046201.Holiday-Rental-Destinations) - [Cumbria Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Cumbria.d6046194.Holiday-Rental-Destinations) - [Yorkshire Holiday Rentals ](https://www.expedia.co.uk/Yorkshire-Holiday-Rentals.d6342462.Travel-Guide-HolidayRentals) - [South Wales Holiday Rentals ](https://www.expedia.co.uk/South-Wales-Holiday-Rentals.d6054274.Travel-Guide-HolidayRentals) - [North Wales Holiday Rentals ](https://www.expedia.co.uk/North-Wales-Holiday-Rentals.d6054276.Travel-Guide-HolidayRentals) - [London Holiday Rentals ](https://www.expedia.co.uk/London-Holiday-Rentals.d178279.Travel-Guide-HolidayRentals) - [York Holiday Rentals ](https://www.expedia.co.uk/York-Holiday-Rentals.d5489.Travel-Guide-HolidayRentals) - [Blackpool Holiday Rentals ](https://www.expedia.co.uk/Blackpool-Holiday-Rentals.d619.Travel-Guide-HolidayRentals) - [Isle of Wight Holiday Rentals ](https://www.expedia.com/Destinations-In-Isle-Of-Wight.d6046218.Vacation-Rental-Destinations) - [Scarborough Holiday Rentals ](https://www.expedia.co.uk/Scarborough-Holiday-Rentals.d5680.Travel-Guide-HolidayRentals) - [Edinburgh Holiday Rentals ](https://www.expedia.co.uk/Edinburgh-Holiday-Rentals.d6069845.Travel-Guide-HolidayRentals) - [Bath Holiday Rentals ](https://www.expedia.co.uk/Bath-Holiday-Rentals.d6084496.Travel-Guide-HolidayRentals) - [Bournemouth Holiday Rentals ](https://www.expedia.co.uk/Bournemouth-Holiday-Rentals.d654.Travel-Guide-HolidayRentals) - [England Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-England.d11218.Holiday-Rental-Destinations) - [Scotland Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Scotland.d11219.Holiday-Rental-Destinations) - [Cornwall Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Cornwall.d6046193.Holiday-Rental-Destinations) - [Wales Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Wales.d11220.Holiday-Rental-Destinations) - [Northern Ireland Holiday Rentals ](https://www.expedia.co.uk/Destinations-In-Northern-Ireland.d11221.Holiday-Rental-Destinations) ## Frequently asked questions ### Can I find a holiday rental in Colon? ### What are some of the best holiday rentals that Colon has to offer? ### How many holiday rentals are there in Colon? ### What’s there to see and do in Colon? ### What’s a holiday rental in Colon like? ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels when you book in the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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