Title: Hotels in Clarksdale, MO - Best Clarksdale Hotels from £54 - Fully Refundable Options - Expedia.co.uk [Holiday Rentals in Clarksdale](https://expedia.co.uk/Clarksdale-Holiday-Rentals.d553248634983445286.Travel-Guide-HolidayRentals)[Clarksdale Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Clarksdale.d553248634983445286.Car-Hire-Guide)[Clarksdale Holidays](https://expedia.co.uk/Clarksdale.d553248634983445286.Holidays-City-Breaks) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Clarksdale, MO from £54 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Clarksdale Pool [](https://www.expedia.co.uk/Hotel-Search?destination=Clarksdale%2C+Missouri%2C+United+States+of+America®ionId=553248634983445286&latLong=39.813608%2C-94.550512&adults=2&startDate=2026-01-05&d1=2026-01-05&endDate=2026-01-07&d2=2026-01-07&amenities=POOL) Apart­ment [](https://www.expedia.co.uk/Hotel-Search?destination=Clarksdale%2C+Missouri%2C+United+States+of+America®ionId=553248634983445286&latLong=39.813608%2C-94.550512&adults=2&startDate=2026-01-05&d1=2026-01-05&endDate=2026-01-07&d2=2026-01-07&lodging=APARTMENT) Cabin [](https://www.expedia.co.uk/Hotel-Search?destination=Clarksdale%2C+Missouri%2C+United+States+of+America®ionId=553248634983445286&latLong=39.813608%2C-94.550512&adults=2&startDate=2026-01-05&d1=2026-01-05&endDate=2026-01-07&d2=2026-01-07&lodging=CABIN) Family friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Clarksdale%2C+Missouri%2C+United+States+of+America®ionId=553248634983445286&latLong=39.813608%2C-94.550512&adults=2&startDate=2026-01-05&d1=2026-01-05&endDate=2026-01-07&d2=2026-01-07&travelerType=family_friendly) Hot tub [](https://www.expedia.co.uk/Hotel-Search?destination=Clarksdale%2C+Missouri%2C+United+States+of+America®ionId=553248634983445286&latLong=39.813608%2C-94.550512&adults=2&startDate=2026-01-05&d1=2026-01-05&endDate=2026-01-07&d2=2026-01-07&amenities=HOT_TUB) Pet friendly [](https://www.expedia.co.uk/Hotel-Search?destination=Clarksdale%2C+Missouri%2C+United+States+of+America®ionId=553248634983445286&latLong=39.813608%2C-94.550512&adults=2&startDate=2026-01-05&d1=2026-01-05&endDate=2026-01-07&d2=2026-01-07&amenities=PETS) ## Check prices for these dates Tonight [22 Dec - 23 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248634983445286&startDate=2025-12-22&endDate=2025-12-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [23 Dec - 24 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248634983445286&startDate=2025-12-23&endDate=2025-12-24&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [26 Dec - 28 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248634983445286&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [2 Jan - 4 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=553248634983445286&startDate=2026-01-02&endDate=2026-01-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Clarksdale hotels ![Pool](https://images.trvl-media.com/lodging/1000000/50000/42200/42192/5baaa282.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking | In-room safe, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/50000/42200/42192/44ee6160.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/50000/42200/42192/bb5c8240.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42200/42192/8fb5321b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Cameron [](https://www.expedia.co.uk/St-Joseph-Hotels-Quality-Inn-Cameron.h42192.Hotel-Information) Cameron 8.4/10 Very good (624) This quiet hotel offers a business-friendly atmosphere with free WiFi, parking, and daily buffet breakfast. Clean rooms provide a peaceful retreat near Beaver Park and Cameron Public Library, with helpful staff ready to assist guests. --- "Nice place for price. Convenient location." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dan £79 includes taxes & fees 21 Jan - 22 Jan 2026 [](https://www.expedia.co.uk/St-Joseph-Hotels-Quality-Inn-Cameron.h42192.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/42200/42165/602776a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking | In-room safe, desk, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/50000/42200/42165/15262450.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42200/42165/w3000h2001x0y1-908111e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 8:00 AM to 10:00 PM, pool loungers](https://images.trvl-media.com/lodging/1000000/50000/42200/42165/eea04022.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Cameron [](https://www.expedia.co.uk/St-Joseph-Hotels-Days-Inn-By-Wyndham-Cameron.h42165.Hotel-Information) Cameron 7.6/10 Good (824) Start each day at this welcoming hotel with a complimentary buffet breakfast before exploring Cameron's attractions. Take a refreshing dip in the indoor pool and enjoy the convenience of free WiFi and parking throughout your stay. --- "Easy to locate, quiet, room was clean, breakfast was OK" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Vicki £54 includes taxes & fees 20 Jan - 21 Jan 2026 [](https://www.expedia.co.uk/St-Joseph-Hotels-Days-Inn-By-Wyndham-Cameron.h42165.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/4200/4180/2dd83c29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout curtains, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/10000/4200/4180/187ddfeb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/4200/4180/d2b9e218.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/4200/4180/ce15b185.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites St Joseph [](https://www.expedia.co.uk/St-Joseph-Hotels-Drury-Inn-Suites-St-Joseph.h4180.Hotel-Information) St. Joseph 9.2/10 Wonderful (1004) Enjoy convenience at this St. Joseph hotel with an indoor pool, fitness centre, and free perks like WiFi, parking, and breakfast. Cool Crest Garden Golf and Glore Psychiatric Museum are nearby, plus attentive staff ensures a quiet retreat. --- "Great place to stay in St. Joseph. Always a clean room, good breakfast and friendly staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) melissa £86 includes taxes & fees 27 Dec - 28 Dec [](https://www.expedia.co.uk/St-Joseph-Hotels-Drury-Inn-Suites-St-Joseph.h4180.Hotel-Information) ![Free breakfast ](https://images.trvl-media.com/lodging/1000000/20000/10500/10417/b317db33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/10500/10417/80e80506.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/10500/10417/a2399256.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/1000000/20000/10500/10417/33a59e94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SureStay Hotel by Best Western Cameron [](https://www.expedia.co.uk/Cameron-Hotels-SureStay-Hotel-By-Best-Western-Cameron.h10417.Hotel-Information) Cameron 8.2/10 Very good (1001) Beautiful flower gardens surround this quiet Cameron hotel with comfortable beds and attentive staff. Enjoy free breakfast, parking, and WiFi after exploring nearby trails and local attractions. The dog-friendly walking path adds extra convenience. --- "The room was very clean, staff were very good and the breakfast is up to the task to do it there instead of elsewhere. It's way more better than the usual, cereal and toast." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David £57 includes taxes & fees 28 Dec - 29 Dec [](https://www.expedia.co.uk/Cameron-Hotels-SureStay-Hotel-By-Best-Western-Cameron.h10417.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/19000000/18180000/18179000/18178902/f5217c79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/19000000/18180000/18179000/18178902/2dbfeb6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/19000000/18180000/18179000/18178902/7977062c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/19000000/18180000/18179000/18178902/b42a1684.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott St. Joseph [](https://www.expedia.co.uk/St-Joseph-Hotels-Fairfield-Inn-Suites-By-Marriott-St-Joseph.h18178902.Hotel-Information) St. Joseph 9.6/10 Exceptional (468) Dive into comfort at this St. Joseph hotel offering a refreshing indoor pool and 24-hour fitness centre. Located near Regal Hollywood and Joe Town Speedway, travellers praise the helpful staff. Free breakfast and WiFi enhance your visit. --- "Easy location, restaurants near by, snacks to go were great " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) phyllis £92 includes taxes & fees 11 Jan - 12 Jan 2026 [](https://www.expedia.co.uk/St-Joseph-Hotels-Fairfield-Inn-Suites-By-Marriott-St-Joseph.h18178902.Hotel-Information) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/7000000/6850000/6846800/6846757/47ec36cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/7000000/6850000/6846800/6846757/8955ad72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/7000000/6850000/6846800/6846757/c6dc4154.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/7000000/6850000/6846800/6846757/2d89b098.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites St. Joseph by IHG [](https://www.expedia.co.uk/St-Joseph-Hotels-Holiday-Inn-Express-Hotel-Suites-St-Joseph.h6846757.Hotel-Information) St. Joseph 9.2/10 Wonderful (790) Swim in the indoor pool or work out in the fitness centre at this well-maintained hotel with clean rooms. Free breakfast, WiFi, and parking add comfort while keeping close to Regal Hollywood and local attractions. --- "We had a wonderful stay. Rooms were very clean and spacious. Staff accommodating and professional. Breakfast very good!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Regina £84 includes taxes & fees 27 Dec - 28 Dec [](https://www.expedia.co.uk/St-Joseph-Hotels-Holiday-Inn-Express-Hotel-Suites-St-Joseph.h6846757.Hotel-Information) ![Fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/110000000/109470000/109463300/109463264/aa4717a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/110000000/109470000/109463300/109463264/da4c15cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillow-top beds, desk, laptop workspace](https://images.trvl-media.com/lodging/110000000/109470000/109463300/109463264/594d24e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillow-top beds, desk, laptop workspace](https://images.trvl-media.com/lodging/110000000/109470000/109463300/109463264/29a35617.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### My Place Hotel St Joseph MO [](https://www.expedia.co.uk/St-Joseph-Hotels-My-Place-Hotel-St-Joesph-MO.h109463264.Hotel-Information) St. Joseph 9.2/10 Wonderful (205) Positioned close to Regal Hollywood and Joe Town Speedway, this hotel offers comfortable accommodation with free WiFi and parking. Business travellers appreciate the 24-hour front desk service during their Missouri stay. --- "Excellent facility and clean rooms." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Javier £69 includes taxes & fees 4 Jan - 5 Jan 2026 [](https://www.expedia.co.uk/St-Joseph-Hotels-My-Place-Hotel-St-Joesph-MO.h109463264.Hotel-Information) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/40000/40000/39991/917e85d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 Queen Bed, Accessible (Smoke Free) | Desk, blackout curtains, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/40000/40000/39991/4ec4b8f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/40000/40000/39991/ebf14a58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 Queen Bed, Accessible (Smoke Free) | Desk, blackout curtains, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/40000/40000/39991/65cb8e48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Cameron [](https://www.expedia.co.uk/St-Joseph-Hotels-Red-Roof-Inn-Cameron.h39991.Hotel-Information) Cameron 8.8/10 Excellent (1001) This serene hotel offers a peaceful atmosphere with plush bedding that travellers love. Wake up to free continental breakfast before exploring nearby Old School of Cameron. Enjoy complimentary WiFi and parking while the attentive staff ensures a pleasant stay. --- "Decent place to stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Darrin £72 includes taxes & fees 28 Dec - 29 Dec [](https://www.expedia.co.uk/St-Joseph-Hotels-Red-Roof-Inn-Cameron.h39991.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/110000/103100/103092/8e39c5c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, iron/ironing board, free cots/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/110000/103100/103092/cebd5503.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/110000/103100/103092/b90af532.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/110000/103100/103092/334d9a3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn St. Joseph [](https://www.expedia.co.uk/St-Joseph-Hotels-Hampton-Inn-St-Joseph.h103092.Hotel-Information) St. Joseph 8.2/10 Very good (655) This hotel offers morning swims in the indoor pool and workouts at the 24-hour fitness centre. Near Cool Crest Garden Golf and Glore Psychiatric Museum, guests praise the helpful staff. Enjoy free breakfast, WiFi, and parking. --- "Was great overall" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mariam £74 includes taxes & fees 28 Dec - 29 Dec [](https://www.expedia.co.uk/St-Joseph-Hotels-Hampton-Inn-St-Joseph.h103092.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/115000000/114260000/114252400/114252394/574523e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi](https://images.trvl-media.com/lodging/115000000/114260000/114252400/114252394/30b33635.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Home2 Suites By Hilton St. Joseph [](https://www.expedia.co.uk/St-Joseph-Hotels-Home2-Suites-By-Hilton-St-Joseph.h114252394.Hotel-Information) St. Joseph 9.2/10 Wonderful (92) "Nice hotel great location. good price" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Steve £91 includes taxes & fees 28 Dec - 29 Dec [](https://www.expedia.co.uk/St-Joseph-Hotels-Home2-Suites-By-Hilton-St-Joseph.h114252394.Hotel-Information) ![Room, 1 King Bed, Hot Tub | Desk, blackout curtains, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/860000/855500/855452/fbe988e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/860000/855500/855452/52e087b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/855500/855452/2c2d2265.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/860000/855500/855452/fd3d7861.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Cameron [](https://www.expedia.co.uk/St-Joseph-Hotels-Super-8-By-Wyndham-Cameron.h855452.Hotel-Information) Cameron 8.4/10 Very good (641) This welcoming hotel offers complimentary WiFi and on-the-go breakfast daily. Clean rooms provide comfort after exploring nearby attractions. The helpful staff ensures a pleasant business or leisure stay with convenient free parking. --- "Very clean and friendly staff. Nice place!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dean £61 includes taxes & fees 8 Jan - 9 Jan 2026 [](https://www.expedia.co.uk/St-Joseph-Hotels-Super-8-By-Wyndham-Cameron.h855452.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/109000000/108200000/108195800/108195771/0938fa17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/109000000/108200000/108195800/108195771/d807d6a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Non Smoking | Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/109000000/108200000/108195800/108195771/c67791cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking | Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/109000000/108200000/108195800/108195771/aedc9baa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Capri Motel By OYO Elwood, Wathena [](https://www.expedia.co.uk/Wathena-Hotels-Capri-Motel-By-OYO-Elwood.h108195771.Hotel-Information) Wathena Located near Pony Express Museum and Remington Nature Centre, this motel offers complimentary WiFi and valet parking. Room service adds comfort to your visit, while Kansas City International Airport is just a 40-minute drive away. £56 includes taxes & fees 31 Dec - 1 Jan 2026 [](https://www.expedia.co.uk/Wathena-Hotels-Capri-Motel-By-OYO-Elwood.h108195771.Hotel-Information) ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/2000000/1140000/1140000/1139931/342fa799.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1140000/1140000/1139931/f4de68bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/2000000/1140000/1140000/1139931/f14c672a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1140000/1140000/1139931/2de574ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Stoney Creek Hotel St. Joseph [](https://www.expedia.co.uk/St-Joseph-Hotels-Stoney-Creek-Hotel-St-Joseph.h1139931.Hotel-Information) St. Joseph 9.0/10 Wonderful (1567) This serene St. Joseph hotel offers a peaceful garden with pond views, hot tub, and fitness centre. Guests love the comfortable beds and complimentary breakfast. Just minutes from Cool Crest Garden Golf and local restaurants. --- "Wonderful place will definitely stay here again " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jessica [](https://www.expedia.co.uk/St-Joseph-Hotels-Stoney-Creek-Hotel-St-Joseph.h1139931.Hotel-Information) ![Interior entrance](https://images.trvl-media.com/lodging/10000000/10000000/9992800/9992788/35d22ebd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/10000000/10000000/9992800/9992788/3ffb20d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/10000000/10000000/9992800/9992788/31b1c36c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/10000000/10000000/9992800/9992788/857c804e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 Cameron, MO [](https://www.expedia.co.uk/Cameron-Hotels-Motel-6-Cameron.h9992788.Hotel-Information) Cameron 7.2/10 Good (281) Located near Beaver Park, this comfortable Cameron motel offers free WiFi and parking. The 24-hour front desk ensures round-the-clock service while nearby attractions and easy access to Kansas City International Airport make it a practical choice. --- "Very clean and comfortable. Great staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joseph £55 includes taxes & fees 23 Dec - 24 Dec [](https://www.expedia.co.uk/Cameron-Hotels-Motel-6-Cameron.h9992788.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/5000000/4220000/4214600/4214555/81b46103.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Double Room, Ensuite (Single Queen ) | Bathroom | Combined shower/bathtub, hair dryer, towels, soap](https://images.trvl-media.com/lodging/5000000/4220000/4214600/4214555/3259f00c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/5000000/4220000/4214600/4214555/cffb314f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/5000000/4220000/4214600/4214555/w1000h963x0y0-b16dd7a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Whiskey Mansion [](https://www.expedia.co.uk/St-Joseph-Hotels-Whiskey-Mansion.h4214555.Hotel-Information) St. Joseph 9.2/10 Wonderful (586) Wake up to a daily full breakfast at this welcoming B&B near Civic Centre Park and Wyeth Tootle Mansion. Guests praise the helpful staff and complimentary parking. Air conditioning ensures comfort throughout your stay in this historic St. Joseph retreat. --- "Bueatiful home, clean, quiet and fantastic service and food!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ellie £105 includes taxes & fees 22 Jan - 23 Jan 2026 [](https://www.expedia.co.uk/St-Joseph-Hotels-Whiskey-Mansion.h4214555.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/19000000/18840000/18838600/18838527/86578d4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Staircase](https://images.trvl-media.com/lodging/19000000/18840000/18838600/18838527/c08809f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Presidential Apartment, 2 Bedrooms, Kitchen, City View | City view](https://images.trvl-media.com/lodging/19000000/18840000/18838600/18838527/5cfeded0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/19000000/18840000/18838600/18838527/9ec7263b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vineyard Mansion & Carriage House Bed & Breakfast [](https://www.expedia.co.uk/St-Joseph-Hotels-Vineyard-Mansion-Carriage-House-Bed-Breakfast.h18838527.Hotel-Information) St. Joseph 9.0/10 Wonderful (197) "Enjoyed our stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Vincent £118 includes taxes & fees 23 Dec - 24 Dec [](https://www.expedia.co.uk/St-Joseph-Hotels-Vineyard-Mansion-Carriage-House-Bed-Breakfast.h18838527.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/180000/171700/171630/683baa8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/180000/171700/171630/d13708b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/180000/171700/171630/23b052a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking, Ground Floor | Free cots/infant beds, rollaway beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/180000/171700/171630/b0334ea4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge Cameron [](https://www.expedia.co.uk/St-Joseph-Hotels-Econo-Lodge-Cameron.h171630.Hotel-Information) Cameron 6.0/10 (159) Explore nearby attractions like Old School of Cameron while enjoying free WiFi and continental breakfast at this welcoming hotel. Convenient parking and comfortable accommodation make for a relaxing Midwest stay. --- "Lovely staff. Very helpful" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Colleen £56 includes taxes & fees 8 Jan - 9 Jan 2026 [](https://www.expedia.co.uk/St-Joseph-Hotels-Econo-Lodge-Cameron.h171630.Hotel-Information) ![Premium bedding, iron/ironing board, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/1000000/50000/41500/41477/8f84e3de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/50000/41500/41477/6328c1ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/1000000/50000/41500/41477/b3fa2b58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/50000/41500/41477/66883004.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AmeriStay Inn [](https://www.expedia.co.uk/St-Joseph-Hotels-AmeriStay-Inn.h41477.Hotel-Information) St. Joseph 5.4/10 (701) This welcoming hotel offers free WiFi, parking, and daily continental breakfast. Located near Glore Psychiatric Museum and Patee House Museum, it provides convenient access to local attractions and is just 33 minutes from MCI airport. --- "Always friendly staff and clean quiet rooms" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jacob [](https://www.expedia.co.uk/St-Joseph-Hotels-AmeriStay-Inn.h41477.Hotel-Information) ![Deluxe Apartment, 3 Bedrooms, Park View | Park view](https://images.trvl-media.com/lodging/75000000/74710000/74704700/74704690/f105b4ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment, 3 Bedrooms, Park View | Living area | 100-inch Smart TV with digital channels, TV, Netflix](https://images.trvl-media.com/lodging/75000000/74710000/74704700/74704690/e4bcc2ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment, 3 Bedrooms, Park View | 3 bedrooms, individually decorated, desk, laptop workspace](https://images.trvl-media.com/lodging/75000000/74710000/74704700/74704690/c3a2436b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment, 3 Bedrooms, Park View | Private kitchen | Full-sized fridge, oven, stovetop, cookware/dishes/utensils](https://images.trvl-media.com/lodging/75000000/74710000/74704700/74704690/228dcaba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cameron Suites [](https://www.expedia.co.uk/Cameron-Hotels-Cameron-Suites.h74704690.Hotel-Information) Cameron Modern apartment featuring a kitchen with full cooking amenities and Smart TVs with Netflix streaming. Unwind after sightseeing under hydromassage showerheads. Free WiFi and convenient laundry facilities enhance your comfortable stay in Cameron. £165 includes taxes & fees 23 Dec - 24 Dec [](https://www.expedia.co.uk/Cameron-Hotels-Cameron-Suites.h74704690.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/49600/49581/771cfdad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/50000/49600/49581/9de5ba3c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/49600/49581/57ce8583.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/50000/49600/49581/183e59b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 Saint Joseph, MO [](https://www.expedia.co.uk/St-Joseph-Hotels-Motel-6-Saint-Joseph.h49581.Hotel-Information) St. Joseph 4.6/10 (1001) Enjoy clean rooms with friendly 24-hour service at this St. Joseph motel. Located near Cool Crest Garden Golf and Glore Psychiatric Museum, with easy access to Kansas City International Airport just 37 minutes away. --- "Did not stay the night. Dirty and not safe. Looked absolutely nothing like the pictures. Should be removed from the site. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Laura £54 includes taxes & fees 29 Dec - 30 Dec [](https://www.expedia.co.uk/St-Joseph-Hotels-Motel-6-Saint-Joseph.h49581.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-05&endDate=2026-01-06®ionId=553248634983445286&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FClarksdale-Hotels.d553248634983445286.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FClarksdale-Hotels.d553248634983445286.Travel-Guide-Hotels) ## Top Clarksdale Hotel Reviews ![Whiskey Mansion](https://images.trvl-media.com/lodging/5000000/4220000/4214600/4214555/81b46103_y.jpg) ### Whiskey Mansion 10/10 Excellent "Everything was perfect. Excellent place to stay. Thanks. Tom" [](https://expedia.co.uk/St-Joseph-Hotels-Whiskey-Mansion.h4214555.Hotel-Information) ![SureStay Hotel by Best Western Cameron](https://images.trvl-media.com/lodging/1000000/20000/10500/10417/b317db33_y.jpg) ### SureStay Hotel by Best Western Cameron 10/10 Excellent "The room was clean staff was very friendly " [](https://expedia.co.uk/Cameron-Hotels-SureStay-Hotel-By-Best-Western-Cameron.h10417.Hotel-Information) ![Stoney Creek Hotel St. Joseph](https://images.trvl-media.com/lodging/2000000/1140000/1140000/1139931/342fa799_y.jpg) ### Stoney Creek Hotel St. Joseph 10/10 Excellent "Everything was great made for a beautiful wonderful great stay very enjoyable and peaceful " [](https://expedia.co.uk/St-Joseph-Hotels-Stoney-Creek-Hotel-St-Joseph.h1139931.Hotel-Information) ![Drury Inn & Suites St Joseph](https://images.trvl-media.com/lodging/1000000/10000/4200/4180/2dd83c29_y.jpg) ### Drury Inn & Suites St Joseph 10/10 Excellent "Great place to stay in St. Joseph. Always a clean room, good breakfast and friendly staff." [](https://expedia.co.uk/St-Joseph-Hotels-Drury-Inn-Suites-St-Joseph.h4180.Hotel-Information) ![My Place Hotel St Joseph MO](https://images.trvl-media.com/lodging/110000000/109470000/109463300/109463264/aa4717a0_y.jpg) ### My Place Hotel St Joseph MO 10/10 Excellent "Best location, you’re in the middle of everything you want to see. Everything was walkable for us. The apartment is very large & we loved it. Just book it!" [](https://expedia.co.uk/St-Joseph-Hotels-My-Place-Hotel-St-Joesph-MO.h109463264.Hotel-Information) ![Ant’s Waterfront 2 Bdrm Cabin w/ Best Sunset View!](https://images.trvl-media.com/lodging/112000000/111900000/111891200/111891118/253408ff_y.jpg) ### Ant’s Waterfront 2 Bdrm Cabin w/ Best Sunset View! 10/10 Excellent "Comfortable accommodations with easy check-in/check-out. Owner was friendly and responsive to questions. Property was clean and well kept. Very peaceful. You can view the river from the cabin. Hammocks and fire pit available. Lots of amenities in kitchen. I would stay here again. Pet friendly. " [](https://expedia.co.uk/St-Joseph-Hotels-Ants-Waterfront-2-Bdrm-Cabin-W-Best-Sunset-View.h111891118.Hotel-Information) ![Motel 6 Cameron, MO](https://images.trvl-media.com/lodging/10000000/10000000/9992800/9992788/35d22ebd_y.jpg) ### Motel 6 Cameron, MO 10/10 Excellent "Very clean and comfortable. Great staff. " [](https://expedia.co.uk/Cameron-Hotels-Motel-6-Cameron.h9992788.Hotel-Information) ![Vineyard Mansion & Carriage House Bed & Breakfast](https://images.trvl-media.com/lodging/19000000/18840000/18838600/18838527/86578d4d_y.jpg) ### Vineyard Mansion & Carriage House Bed & Breakfast 10/10 Excellent "The best of the best." [](https://expedia.co.uk/St-Joseph-Hotels-Vineyard-Mansion-Carriage-House-Bed-Breakfast.h18838527.Hotel-Information) ![Motel 6 Saint Joseph, MO](https://images.trvl-media.com/lodging/1000000/50000/49600/49581/771cfdad_y.jpg) ### Motel 6 Saint Joseph, MO 8/10 Good "With the remodeling construction going on it was a bit of a mess but the areas we were in were completed and were really nice and new. We didn't have anything to hang out clothes on so used the bathroom hook and shower bar. We didn't have a lot but they had to hang or lay out over our bed. The lady who checked us in was very friendly and good." [](https://expedia.co.uk/St-Joseph-Hotels-Motel-6-Saint-Joseph.h49581.Hotel-Information) ## More cheap stays in Clarksdale ![Days Inn by Wyndham Cameron](https://images.trvl-media.com/lodging/1000000/50000/42200/42165/602776a9_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Days Inn by Wyndham Cameron 601 E. Bryan Road Cameron MO £54 20 Jan - 21 Jan 2026 includes taxes & fees 7.6/10 Good! (824 reviews) [](https://expedia.co.uk/St-Joseph-Hotels-Days-Inn-By-Wyndham-Cameron.h42165.Hotel-Information) ![My Place Hotel St Joseph MO](https://images.trvl-media.com/lodging/110000000/109470000/109463300/109463264/aa4717a0_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### My Place Hotel St Joseph MO 3621 N Village Dr St. Joseph MO £69 4 Jan - 5 Jan 2026 includes taxes & fees 9/10 Wonderful! (203 reviews) [](https://expedia.co.uk/St-Joseph-Hotels-My-Place-Hotel-St-Joesph-MO.h109463264.Hotel-Information) ![Red Roof Inn Cameron](https://images.trvl-media.com/lodging/1000000/40000/40000/39991/917e85d1_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Red Roof Inn Cameron 501 Northland Drive Cameron MO £72 28 Dec - 29 Dec includes taxes & fees 8.6/10 Excellent! (1,001 reviews) [](https://expedia.co.uk/St-Joseph-Hotels-Red-Roof-Inn-Cameron.h39991.Hotel-Information) ![Hampton Inn St. Joseph](https://images.trvl-media.com/lodging/1000000/110000/103100/103092/8e39c5c8_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hampton Inn St. Joseph 3928 Frederick Ave St. Joseph MO £74 28 Dec - 29 Dec includes taxes & fees 8/10 Very Good! (654 reviews) [](https://expedia.co.uk/St-Joseph-Hotels-Hampton-Inn-St-Joseph.h103092.Hotel-Information) ![Holiday Inn Express Hotel & Suites St. Joseph by IHG](https://images.trvl-media.com/lodging/7000000/6850000/6846800/6846757/47ec36cb_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Holiday Inn Express Hotel & Suites St. Joseph by IHG 3600 N. Village Dr. St. Joseph MO £84 27 Dec - 28 Dec includes taxes & fees 9/10 Wonderful! (789 reviews) [](https://expedia.co.uk/St-Joseph-Hotels-Holiday-Inn-Express-Hotel-Suites-St-Joseph.h6846757.Hotel-Information) ![Fairfield Inn & Suites by Marriott St. Joseph](https://images.trvl-media.com/lodging/19000000/18180000/18179000/18178902/f5217c79_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Fairfield Inn & Suites by Marriott St. Joseph 4779 Tuscany Drive St. Joseph MO £92 11 Jan - 12 Jan 2026 includes taxes & fees 9.6/10 Exceptional! (467 reviews) [](https://expedia.co.uk/St-Joseph-Hotels-Fairfield-Inn-Suites-By-Marriott-St-Joseph.h18178902.Hotel-Information) ## Frequently asked questions ### Where is the best place to stay in Clarksdale? ### What are some of the best holiday rentals that Clarksdale has to offer? ### If I need to cancel my hotel reservation in Clarksdale, will I receive a refund? ### What is staying in Clarksdale like? ### What is there to see in Clarksdale? ### What's the weather like in Clarksdale? ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - More ways to book - [Hotels near Adam-ondi-Ahman ](https://www.expedia.co.uk/Adam-Ondi-Ahman-Hotels.0-l553248635919972340-0.Travel-Guide-Filter-Hotels) - [Agency Hotels ](https://www.expedia.co.uk/Agency-Hotels.d553248634983462091.Travel-Guide-Hotels) - [Albany Hotels ](https://www.expedia.co.uk/Albany-Hotels.d553248634983073653.Travel-Guide-Hotels) - [Amazonia Hotels ](https://www.expedia.co.uk/Amazonia-Hotels.d3000349270.Travel-Guide-Hotels) - 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