Central United States Holidays from £752

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Your Central United States Holiday

When it's time to set off on your next unforgettable adventure, a holiday package to Central United States is the answer. From this destination's friendly locals to all the other incredible things it's renowned for, there's a lot to discover. With so much to see and do on a trip to Central United States, it can be difficult to know where to begin. Kick off your travels in New York at Times Square and Central Park — two leading attractions here. Another great city worthy of a spot on your itinerary is Orlando. Don't miss Universal Studios Florida and Orlando International Premium Outlets. From the moment you book your Central United States holiday to when you return home, Expedia has your back every step of the way.

Top Central United States Flight + Hotel Deals

Price found within the past 48 hours. Click for updated prices.
Hotel Riu Plaza Chicago

Hotel Riu Plaza Chicago

4 out of 5
Downtown Chicago
Price was £1,055, price is now £752 per person
£752
per person
2 Apr - 6 Apr
found 1 day ago
Return direct flight included
Dublin (DUB) to Chicago (ORD)
9.4/10 Exceptional! (2,790 reviews)
Clean amenities, amazing food, and great service!

Reviewed on 27 Feb 2026

1 Hotel Nashville

1 Hotel Nashville

5 out of 5
Downtown Nashville
Save 100% on your flight
Price was £1,370, price is now £966 per person
£966
per person
2 Apr - 6 Apr
found 1 day ago
Return direct flight included
Dublin (DUB) to Nashville (BNA)
9.2/10 Wonderful! (924 reviews)
The problem is their bedding. It’s synthetic so you wake up sweating and then you get cold…then you wake up again sweaty. They need breathable bedding. Our shower floor was also greasy which was kinda gross. Food was really expensive but not great.

Reviewed on 24 Feb 2026

Waymore's Guest House & Casual Club

Waymore's Guest House & Casual Club

3.5 out of 5
East Nashville
Price was £1,522, price is now £1,077 per person
£1,077
per person
10 May - 17 May
found 5 hours ago
Return direct flight included
London (LON) to Nashville (BNA)
9.4/10 Exceptional! (1,394 reviews)
We had a pleasant experience with all the people that worked at the Waymore. but: This is definitely for hipsters. We didn't mind, it was nice to chat with some. We enjoyed breakfast, and Drinks on the rooftop were the best in Nashville ( at least where we went). BUT the room was a concrete block that smelled like mildew. hence 4 stars

Reviewed on 27 Feb 2026

Trump International Hotel & Tower Chicago

Trump International Hotel & Tower Chicago

5 out of 5
Downtown Chicago
Price was £2,312, price is now £1,651 per person
£1,651
per person
17 May - 22 May
found 3 hours ago
Return flight included
London (LHR) to Chicago (ORD)
9.4/10 Exceptional! (1,773 reviews)
We had a great stay!

Reviewed on 23 Feb 2026

Virgin Hotels Nashville

Virgin Hotels Nashville

4.5 out of 5
Downtown Nashville
Save 100% on your flight
Price was £1,763, price is now £1,266 per person
£1,266
per person
21 Apr - 26 Apr
found 1 day ago
Return flight included
Dublin (DUB) to Nashville (BNA)
9.4/10 Exceptional! (2,293 reviews)
Staff was great and room clean. Loved that they gave us endless supply of water. One negative was we got married on this trip and my husband wanted to surprise me with rose petals on bed which the hotel says they do. But when they found out we booked thru expedia they would not do it. I was very disappointed.

Reviewed on 16 Feb 2026

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Where to stay in Central United States

Find the best Central United States areas and neighborhoods for the activities you enjoy most. Learn more about Central United States
Downtown Chicago featuring a city

Downtown Chicago

1 out of top 10 points of interest in this area

The heart of the Midwest’s glittering metropolis has many offerings, from shopping and dining to parks, museums and exciting contemporary public art.

Find hotels in Downtown Chicago

Central United States Essential Information

Language
English
Currency
U.S dollars
Closest Airport
O'Hare Intl. Airport (ORD)

Top hotels in Central United States

Congress Plaza Hotel

Congress Plaza Hotel

3.5 out of 5
520 South Michigan Avenue Chicago IL
Fully refundableReserve now, pay when you stay
The price is £150 per night from 27 Mar to 28 Mar
£150
27 Mar - 28 Mar
includes taxes & fees
8/10 Very Good! (9,892 reviews)
We mainly go to Chicago for medical appointments and it is *so awesome* that you can actually open the windows here.That is the main reason we chose it. Because Dad has cancer we aired it out and then ran our own air purifier. No bad smells or anything, we're just being cautious because of his health. ...

Reviewed on 27 Feb 2026

Congress Plaza Hotel
Hotel Riu Plaza Chicago

Hotel Riu Plaza Chicago

4 out of 5
150 East Ontario Street Chicago IL
Fully refundableReserve now, pay when you stay
The price is £119 per night from 4 Mar to 5 Mar
£119
4 Mar - 5 Mar
includes taxes & fees
9.4/10 Exceptional! (3,422 reviews)
This is our new go-to in the city. Great location, very comfortable beds. Pillows are unusually small, but they brought more quickly. Large bathroom with double sinks. Breakfast buffet was excellent and plentiful. Shout out to Frank during our very late check-in. Very friendly, funny and was quick ...

Reviewed on 27 Feb 2026

Hotel Riu Plaza Chicago
DoubleTree by Hilton Hotel & Suites Houston by the Galleria

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

4 out of 5
5353 Westheimer Rd Houston TX
Fully refundableReserve now, pay when you stay
The price is £102 per night from 29 Mar to 30 Mar
£102
29 Mar - 30 Mar
includes taxes & fees
8.2/10 Very Good! (3,429 reviews)
They had us waiting for hours before we could check in they said the system was down and they did not give us any accommodations they were double booking rooms our room had no toilet paper. I will Never stay here again!

Reviewed on 27 Feb 2026

DoubleTree by Hilton Hotel & Suites Houston by the Galleria
See all 304,465 properties in Central United States
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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All Inclusive Holidays
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Beach Holidays
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Family Friendly Holidays

Popular places to visit

River Walk featuring night scenes and a river or creek

River Walk

5/5(21 reviews)

River Walk is just one of the places to see in San Antonio, so why not enjoy the other things to explore during your travels? Discover the fascinating museums and shops in this walkable area.

River Walk
Dollywood which includes rides and signage

Dollywood

4.5/5(3 reviews)

This amusement park owned by country singer Dolly Parton lures fans with its roller coasters and children’s rides, museums and live music and theater shows.

Dollywood
Wrigley Field featuring a city, a sporting event and city views

Wrigley Field

4.5/5(40 reviews)

Tour the iconic grounds and catch a game March through September at Chicago’s beloved baseball stadium.

Wrigley Field

Frequently asked questions

Can I cancel my flight booking to Central United States due to COVID-19?
Our helpful Customer Service Portal is your one-stop shop for most travel queries, including about flight cancellations and changes due to COVID-19. For extra peace of mind, we recommend looking over the terms and conditions of your chosen airline before booking your tickets.
What's the best way to find cheap flights to Central United States that have flexible change policies?
Search for low-cost flights to Central United States, then select "No change fee" underneath the "Flexible change policies" filter. It's that easy. We appreciate that plans change and flexibility is important, so you can book with confidence with Expedia.
What are some of the general tips for travellers to Central United States during the COVID-19 outbreak?
If it's your first time travelling during the COVID-19 pandemic, you'll no doubt notice a few more standards and rules in place. Follow these tips and make your escape to Central United States go off without a hitch:
  • Research if any travel restrictions apply to your destination and origin before booking your flight. Also check if there are any special conditions you'll need to follow on arrival, such as health testing.
  • Keep your face mask on even during airport screening. A TSA officer will require you to lower your mask temporarily for ID purposes.
  • To reduce the risk of cross-contamination, place your boarding pass on the reader yourself and then hold it up for inspection. Do not hand your pass directly to a TSA agent.
  • One liquid hand sanitizer container is now permitted in your carry-on baggage. It must be no larger than 12 oz (350 ml), and you'll have to take it out of your bag for screening.
  • To reduce handling during screening, place items such as your phone and loose change into your carry-on rather than the bins.
  • Separate any food you have for X-ray scanning. Food items often set off the alarm. Placing them in a clear plastic bag and into a bin reduces the need for a TSA agent to touch and inspect your belongings.

Which airlines fly to Central United States?
Let American Airlines take you there. This popular carrier runs 799 flights every month to Kansas City Intl. Airport (MCI), a Central United States gateway.
How can I find cheap tickets to Central United States?
In the last seven days, was the best price for a flight to Central United States. If you'd love to save even more, book ahead of time and be flexible with your dates. Search for your airfare to Central United States, then see prices for similar time frames by clicking on our "flexible dates" link.
How much is a flight to Central United States?
One-way flights departing from () sold for as low as in the last seven days. During this period, the cost of a return ticket to Central United States ranged between and . If you spot a good deal, book quickly — these prices don't hang around for long.
What are the most popular airports to fly into in Central United States?
Start planning your Central United States adventure by booking a ticket on one of the 3752 flights per month to Kansas City Intl. Airport (MCI). This is the region's principal gateway.
When is the cheapest time to fly to Central United States?
Flying on a Tuesday, followed by a Monday, is usually the best way to score the cheapest flight. Stay away from the weekends if you can, because Saturday is typically the costliest day. Spend the cash you saved having a blast in Central United States instead!
How much is a plane ticket to Central United States?
In the last seven days, fares to Central United States fluctuated from to .
Which airlines with flights to Central United States employ COVID-19 cleanliness policies?
As lockdowns start to lift, many airlines are back in business with new strategies including social distancing and an increased supply of sanitizer and face masks. Here's what some carriers are doing to ease the spread of COVID-19:
  • American Airlines - this airline is known for providing passenger masks and cleaning with disinfectant.
  • United Airlines - this airline is known for providing passenger masks and cleaning with disinfectant.
  • Delta - this airline is known for electrostatic cleaning and cleaning with disinfectant.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. Flight-inclusive packages are ATOL protected.