Title: TOP Business Hotels in Central Pennsylvania, PA for 2026 | Expedia.co.uk [Central Pennsylvania Travel Guide](https://expedia.co.uk/Central-Pennsylvania.dx6057564)[Hotels in Central Pennsylvania](https://expedia.co.uk/Central-Pennsylvania-Hotels.d6057564.Travel-Guide-Hotels)[Holiday Rentals in Central Pennsylvania](https://expedia.co.uk/Central-Pennsylvania-Holiday-Rentals.d6057564.Travel-Guide-HolidayRentals)[Flights to Central Pennsylvania](https://expedia.co.uk/Cheap-Flights-To-Central-Pennsylvania.d6057564.Travel-Guide-Flights)[Things to do in Central Pennsylvania](https://expedia.co.uk/Things-To-Do-In-Central-Pennsylvania.d6057564.Travel-Guide-Activities)[Central Pennsylvania Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Central-Pennsylvania.d6057564.Car-Hire-Guide)[Central Pennsylvania Holidays](https://expedia.co.uk/Central-Pennsylvania.d6057564.Holidays-City-Breaks) ![Central Pennsylvania which includes heritage architecture and a square or plaza](https://images.trvl-media.com/place/6057564/aeb8cab0-9a11-4b00-860c-14bba126e487.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Business Hotels in Central Pennsylvania - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Central Pennsylvania Business Hotels Tonight [19 Dec - 20 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6057564&startDate=2025-12-19&endDate=2025-12-20&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [20 Dec - 21 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6057564&startDate=2025-12-20&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [19 Dec - 21 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6057564&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [26 Dec - 28 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6057564&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Central Pennsylvania business-friendly hotels ![Front of property](https://images.trvl-media.com/lodging/32000000/31710000/31709500/31709458/71182762.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/32000000/31710000/31709500/31709458/5cc34561.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/32000000/31710000/31709500/31709458/800b8d30.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite, 1 Queen Bed with Sofa Bed, Non Smoking | Egyptian cotton sheets, premium bedding, pillow-top beds, desk](https://images.trvl-media.com/lodging/32000000/31710000/31709500/31709458/6184cc76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Microtel Inn & Suites by Wyndham Carlisle [](https://www.expedia.co.uk/Carlisle-Hotels-Microtel-Inn-Suites-By-Wyndham-Carlisle.h31709458.Hotel-Information) Carlisle 9.6/10 Exceptional (1219) "Great, well-kept hotel: comfy rooms, everything new and clean" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dosinda £59 includes taxes & fees 23 Dec - 24 Dec [](https://www.expedia.co.uk/Carlisle-Hotels-Microtel-Inn-Suites-By-Wyndham-Carlisle.h31709458.Hotel-Information) ![Standard Room, 1 Queen Bed, Non Smoking, Refrigerator & Microwave | Premium bedding, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/1000000/70000/64200/64120/5517b0e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 King Beds Family Suite | Premium bedding, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/1000000/70000/64200/64120/a194c7c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/70000/64200/64120/2d73c739.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/70000/64200/64120/30851eb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Larkspur Landing Select Carlisle [](https://www.expedia.co.uk/Carlisle-Hotels-Larkspur-Landing-Select-Carlisle.h64120.Hotel-Information) Carlisle 9.0/10 Wonderful (1002) "Clean, quiet, lovely room, decent breakfast, enjoyed it very much." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rebecca £52 includes taxes & fees 1 Jan - 2 Jan 2026 [](https://www.expedia.co.uk/Carlisle-Hotels-Larkspur-Landing-Select-Carlisle.h64120.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/4000000/3940000/3936400/3936379/d0cf6542.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free continental breakfast ](https://images.trvl-media.com/lodging/4000000/3940000/3936400/3936379/2391d59d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 King Bed, Non Smoking (Deluxe Executive Room) | Room amenity](https://images.trvl-media.com/lodging/4000000/3940000/3936400/3936379/407de68d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/4000000/3940000/3936400/3936379/64e881d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Chambersburg [](https://www.expedia.co.uk/Gettysburg-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Chambersburg.h3936379.Hotel-Information) Chambersburg 9.0/10 Wonderful (1002) "Excellent hotel. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Diane £71 includes taxes & fees 22 Dec - 23 Dec [](https://www.expedia.co.uk/Gettysburg-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Chambersburg.h3936379.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/5000000/4290000/4284400/4284314/a9437f41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4290000/4284400/4284314/00a91189.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast ](https://images.trvl-media.com/lodging/5000000/4290000/4284400/4284314/fb840e4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/5000000/4290000/4284400/4284314/b6af1add.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Donegal by IHG [](https://www.expedia.co.uk/Greensburg-Hotels-Holiday-Inn-Express-Hotel-Suites-Donegal.h4284314.Hotel-Information) Stahlstown 9.2/10 Wonderful (1000) "Everything was great, room, amenities, staff was phenomenal " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Adam £95 includes taxes & fees 15 Jan - 16 Jan 2026 [](https://www.expedia.co.uk/Greensburg-Hotels-Holiday-Inn-Express-Hotel-Suites-Donegal.h4284314.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/4000000/3910000/3900600/3900515/765a3565.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/4000000/3910000/3900600/3900515/a1c3a7c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Two double beds non smoking | Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/4000000/3910000/3900600/3900515/03d67d46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, coffee/tea maker](https://images.trvl-media.com/lodging/4000000/3910000/3900600/3900515/5709a9ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### University Hotel & Suites Shippensburg, Trademark by Wyndham [](https://www.expedia.co.uk/Gettysburg-Hotels-Clarion-Hotel-Suites-University-Shippensburg.h3900515.Hotel-Information) Shippensburg 8.8/10 Excellent (993) "Clean room excellent staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joe £65 includes taxes & fees 22 Dec - 23 Dec [](https://www.expedia.co.uk/Gettysburg-Hotels-Clarion-Hotel-Suites-University-Shippensburg.h3900515.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/5700/5647/9600d7e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Café](https://images.trvl-media.com/lodging/1000000/10000/5700/5647/16c0bee6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bicycling](https://images.trvl-media.com/lodging/1000000/10000/5700/5647/ddddee8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/10000/5700/5647/ed4c9a21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Gettysburg [](https://www.expedia.co.uk/Gettysburg-Hotels-Gettysburg-Hotel.h5647.Hotel-Information) Gettysburg Historic District 9.4/10 Exceptional (1180) "Hotel was beautiful and centrally located. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Deirdre £78 includes taxes & fees 2 Jan - 3 Jan 2026 [](https://www.expedia.co.uk/Gettysburg-Hotels-Gettysburg-Hotel.h5647.Hotel-Information) ![Aerial view](https://images.trvl-media.com/lodging/2000000/1530000/1521500/1521457/b7064677.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1530000/1521500/1521457/2a8ee0d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/2000000/1530000/1521500/1521457/c58871f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Serves dinner and happy hour](https://images.trvl-media.com/lodging/2000000/1530000/1521500/1521457/b2b21377.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wyndham Gettysburg Hotel & Conference Center [](https://www.expedia.co.uk/Gettysburg-Hotels-Wyndham-Gettysburg.h1521457.Hotel-Information) Gettysburg 8.8/10 Excellent (1538) "It’s a great place to stay with family" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Damaris £66 includes taxes & fees 5 Jan - 6 Jan 2026 [](https://www.expedia.co.uk/Gettysburg-Hotels-Wyndham-Gettysburg.h1521457.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/900000/891500/891447/fe55e129.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom, Accessible, Non Smoking | Hypo-allergenic bedding, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/900000/891500/891447/b2c2dd85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast ](https://images.trvl-media.com/lodging/1000000/900000/891500/891447/a78d2b80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/900000/891500/891447/5dbf77a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Inn & Suites by Radisson, Harrisburg Northeast - Hershey [](https://www.expedia.co.uk/Harrisburg-Hotels-Country-Inn-Suites-By-Radisson.h891447.Hotel-Information) Harrisburg 9.0/10 Wonderful (1533) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gretta £54 includes taxes & fees 24 Dec - 25 Dec [](https://www.expedia.co.uk/Harrisburg-Hotels-Country-Inn-Suites-By-Radisson.h891447.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/90000/85300/85204/628583e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/90000/85300/85204/05c9bf3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property – evening/night](https://images.trvl-media.com/lodging/1000000/90000/85300/85204/8e4cb24b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/90000/85300/85204/3ee5be52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spark by Hilton Mechanicsburg [](https://www.expedia.co.uk/Mechanicsburg-Hotels-Spark-By-Hilton-Mechanicsburg.h85204.Hotel-Information) Mechanicsburg 8.2/10 Very good (48) "Very good hotel definitely would recommend " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tiffany £70 includes taxes & fees 24 Dec - 25 Dec [](https://www.expedia.co.uk/Mechanicsburg-Hotels-Spark-By-Hilton-Mechanicsburg.h85204.Hotel-Information) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/20000/11800/11790/d439e5a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/1000000/20000/11800/11790/0e788116.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking | Desk, blackout curtains, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/11800/11790/f584a61a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11800/11790/944a3bdf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Harrisburg [](https://www.expedia.co.uk/Harrisburg-Hotels-Baymont-By-Wyndham-Harrisburg.h11790.Hotel-Information) Harrisburg 8.6/10 Excellent (1711) "Nice place " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Deanna £42 includes taxes & fees 21 Dec - 22 Dec [](https://www.expedia.co.uk/Harrisburg-Hotels-Baymont-By-Wyndham-Harrisburg.h11790.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-03&endDate=2026-01-04®ionId=6057564&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Central Pennsylvania Hotel Reviews ![The Nittany Lion Inn](https://images.trvl-media.com/lodging/1000000/30000/28400/28356/7c217256_y.jpg) ### The Nittany Lion Inn 10/10 Excellent "This is a great place" [](https://expedia.co.uk/State-College-Hotels-The-Nittany-Lion-Inn.h28356.Hotel-Information) ![Lancaster Marriott at Penn Square](https://images.trvl-media.com/lodging/3000000/2480000/2473700/2473637/619a3e51_y.jpg) ### Lancaster Marriott at Penn Square 10/10 Excellent "Very friendly check in , quick and professional " [](https://expedia.co.uk/Lancaster-Hotels-Lancaster-Marriott-At-Penn-Square.h2473637.Hotel-Information) ![Holiday Inn Express - Harrisburg East by IHG](https://images.trvl-media.com/lodging/1000000/10000/400/376/89809a62_y.jpg) ### Holiday Inn Express - Harrisburg East by IHG 10/10 Excellent "All the above " [](https://expedia.co.uk/Harrisburg-Hotels-Holiday-Inn-Express-Harrisburg-East.h376.Hotel-Information) ![Lancaster Suites ](https://images.trvl-media.com/lodging/1000000/560000/551000/550914/3556501c_y.jpg) ### Lancaster Suites 10/10 Excellent "I had a very good stay as it was my third time in Lancaster over the past few months." [](https://expedia.co.uk/Lancaster-Hotels-Lancaster-Suites.h550914.Hotel-Information) ![Toftrees Golf Resort](https://images.trvl-media.com/lodging/1000000/10000/9700/9676/ec553fc8_y.jpg) ### Toftrees Golf Resort 10/10 Excellent "The hotel is 5 star ! " [](https://expedia.co.uk/State-College-Hotels-Toftrees-Golf-Resort.h9676.Hotel-Information) ![Days Inn by Wyndham Hershey](https://images.trvl-media.com/lodging/1000000/20000/16000/15999/3a620bf0_y.jpg) ### Days Inn by Wyndham Hershey 10/10 Excellent "Room was clean, staff was polite and answered whatever questions I had. " [](https://expedia.co.uk/Hershey-Hotels-Days-Inn-By-Wyndham-Hershey.h15999.Hotel-Information) ![Parkview Inn & Suites Lancaster ](https://images.trvl-media.com/lodging/1000000/810000/809200/809150/7d398240_y.jpg) ### Parkview Inn & Suites Lancaster 10/10 Excellent "Rooms were very spacious and CLEAN! Breakfast was terrific, pool and hot tub were an added bonus in the winter. Even more important, the front desk and manager addressed every single question and request we had for our group of 8\. Thank you so much! I’ll be back in the spring with my mom for Sight & Sound tickets! " [](https://expedia.co.uk/Lancaster-Hotels-Country-Inn-Suites-By-Radisson.h809150.Hotel-Information) ![Motel 6 Lancaster, PA](https://images.trvl-media.com/lodging/1000000/130000/124100/124003/f175975a_y.jpg) ### Motel 6 Lancaster, PA 10/10 Excellent "The courteous staff who were able to answer all my questions and address any concerns I had." [](https://expedia.co.uk/Lancaster-Hotels-Motel-6-Lancaster.h124003.Hotel-Information) ![Days Inn & Suites by Wyndham Lancaster Amish Country](https://images.trvl-media.com/lodging/2000000/1100000/1098100/1098098/dcbdbb0b_y.jpg) ### Days Inn & Suites by Wyndham Lancaster Amish Country 10/10 Excellent "Very courteous staff who explained the amenities on arrival. The facility is clean but dated. The shower water was warm and not hot enough for my liking. It is exactly what you would expect for the price." [](https://expedia.co.uk/Lancaster-Hotels-Days-Inn-Suites-By-Wyndham-Lancaster-Amish-Country.h1098098.Hotel-Information) ## Frequently asked questions ### How much do business hotels in Central Pennsylvania cost? ### How many business hotels are there in Central Pennsylvania? ### Why book your business hotel in Central Pennsylvania with Expedia? ### How can I find cheap business hotels in Central Pennsylvania? ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - More ways to book - [5 Star Hotels in Tyrone ](https://www.expedia.co.uk/5Star-Tyrone-Hotels.s50-0-d6204539.Travel-Guide-Filter-Hotels) - [Gay-Friendly Hotels in Adrian Furnace ](https://www.expedia.co.uk/Adrian-Furnace-Hotels-Gay-Friendly-Hotel.0-0-d3000183737-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Altoona ](https://www.expedia.co.uk/Altoona-Hotels-Budget-Hotels.0-0-d6057570-tBudgetHotels.Travel-Guide-Filter-Hotels) - [Gay-Friendly Hotels in Altoona ](https://www.expedia.co.uk/Altoona-Hotels-Gay-Friendly-Hotel.0-0-d6057570-tGayFriendlyHotel.Travel-Guide-Filter-Hotels) - 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