Title: TOP Luxury Hotels in Central Missouri, MO for 2025 - Central Missouri Upscale Hotels | Expedia.co.uk [Central Missouri Travel Guide](https://expedia.co.uk/Central-Missouri.dx6058776)[Hotels in Central Missouri](https://expedia.co.uk/Central-Missouri-Hotels.d6058776.Travel-Guide-Hotels)[Holiday Rentals in Central Missouri](https://expedia.co.uk/Central-Missouri-Holiday-Rentals.d6058776.Travel-Guide-HolidayRentals)[Flights to Central Missouri](https://expedia.co.uk/Cheap-Flights-To-Central-Missouri.d6058776.Travel-Guide-Flights)[Things to do in Central Missouri](https://expedia.co.uk/Things-To-Do-In-Central-Missouri.d6058776.Travel-Guide-Activities)[Central Missouri Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Central-Missouri.d6058776.Car-Hire-Guide)[Central Missouri Holidays](https://expedia.co.uk/Central-Missouri.d6058776.Holidays-City-Breaks) ![Columbia showing wild flowers](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/257000/257714-Central-Missouri.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find luxury hotels in Central Missouri, MO ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Central Missouri Luxury Hotels Tonight [15 Oct - 16 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6058776&startDate=2025-10-15&endDate=2025-10-16&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [16 Oct - 17 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6058776&startDate=2025-10-16&endDate=2025-10-17&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [17 Oct - 19 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6058776&startDate=2025-10-17&endDate=2025-10-19&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [24 Oct - 26 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6058776&startDate=2025-10-24&endDate=2025-10-26&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Central Missouri Luxury Hotels ![Studio Suite, 1 King Bed, Non Smoking | Desk, iron/ironing board, free cots/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/18900/18803/77d8da33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/18900/18803/0abef2e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite, Multiple Beds, Non Smoking | Desk, iron/ironing board, free cots/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/18900/18803/e7ee761d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/20000/18900/18803/7ea5455a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ramada by Wyndham Columbia Columbia 7.4/10 Good (1017) "A very nice, quiet, restful stay" £54 includes taxes & fees 5 Nov - 6 Nov [](https://www.expedia.co.uk/Columbia-Hotels-Ramada-By-Wyndham-Columbia.h18803.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/5000000/4800000/4790100/4790037/4cb82576.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bars/lounges, cocktail bar](https://images.trvl-media.com/lodging/5000000/4800000/4790100/4790037/d57fed98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4800000/4790100/4790037/d2b3af17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Accessible (Private Access to Patio) | 1 bedroom, premium bedding, down duvets, pillow-top beds](https://images.trvl-media.com/lodging/5000000/4800000/4790100/4790037/de4af1ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### voco, The Tiger Hotel, Columbia, MO by IHG Columbia 8.8/10 Excellent (1000) "Excellent location with wonderful staff!" £129 includes taxes & fees 19 Oct - 20 Oct [](https://www.expedia.co.uk/Columbia-Hotels-The-Tiger-Hotel.h4790037.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/7e36eb59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![5 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/40992baf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/41084352.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/7a41768f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lodge Of Four Seasons Golf Resort, Marina & Spa Lake Ozark 7.4/10 Good (1037) "Friendly staff nice room restaurant was extremely good " £78 includes taxes & fees 15 Nov - 16 Nov [](https://www.expedia.co.uk/Osage-Beach-Hotels-Lodge-Of-Four-Seasons-Golf-Resort.h40728.Hotel-Information) ![Seasonal outdoor pool, pool loungers](https://images.trvl-media.com/lodging/3000000/2020000/2015400/2015357/21eb378b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Ballroom](https://images.trvl-media.com/lodging/3000000/2020000/2015400/2015357/b09c0391.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/3000000/2020000/2015400/2015357/e77a4ef2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch, dinner served; Caribbean cuisine ](https://images.trvl-media.com/lodging/3000000/2020000/2015400/2015357/926b808f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Camden on the Lake Resort & Spa Lake Ozark 9.0/10 Wonderful (1008) "Super convenient to the boat rental and fuel dock. " £107 includes taxes & fees 13 Nov - 14 Nov [](https://www.expedia.co.uk/Osage-Beach-Hotels-Camden-On-The-Lake-Resort-Spa.h2015357.Hotel-Information) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/800000/794300/794290/1e51ead0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/800000/794300/794290/5f6cb0fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillow-top beds, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/800000/794300/794290/4b6bed2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Suite | Pillow-top beds, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/800000/794300/794290/b975f919.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Bothwell Sedalia Central District, an Ascend Collection Hotel Sedalia Downtown Historic District 9.2/10 Wonderful (561) "Historic hotel that was a great stop for our trip on the Katy Trail." £95 includes taxes & fees 16 Oct - 17 Oct [](https://www.expedia.co.uk/Clinton-Hotels-Hotel-Bothwell-Sedalia-Central-District.h794290.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/8000000/7770000/7768600/7768577/350205ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/8000000/7770000/7768600/7768577/abe0b627.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/8000000/7770000/7768600/7768577/a72704ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 Queen Bed, Smoking | Free WiFi, bed sheets](https://images.trvl-media.com/lodging/8000000/7770000/7768600/7768577/70ee9896.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Laci's Country Inn Knob Noster 7.0/10 Good (159) "Nice stay. " £54 includes taxes & fees 17 Oct - 18 Oct [](https://www.expedia.co.uk/Clinton-Hotels-Lacis-Country-Inn.h7768577.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/13000000/12550000/12546300/12546284/2c317c73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/13000000/12550000/12546300/12546284/c428cb4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Room, 1 King Bed, Non Smoking, Refrigerator & Microwave | Down duvets, pillow-top beds, desk, blackout curtains](https://images.trvl-media.com/lodging/13000000/12550000/12546300/12546284/fd258818.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/13000000/12550000/12546300/12546284/bd7f5440.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Columbia Inn Columbia 8.8/10 Excellent (1187) "Great place to stay! " £61 includes taxes & fees 2 Nov - 3 Nov [](https://www.expedia.co.uk/Columbia-Hotels-Best-Western-Plus-Columbia-Inn.h12546284.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/460000/459700/459668/52bc64ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free toiletries, hair dryer, towels, soap](https://images.trvl-media.com/lodging/1000000/460000/459700/459668/3db07fad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed | Desk, laptop workspace, blackout curtains, free WiFi](https://images.trvl-media.com/lodging/1000000/460000/459700/459668/a99e46d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout curtains, free WiFi](https://images.trvl-media.com/lodging/1000000/460000/459700/459668/0665f04c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Columbia Clark Lane Columbia 6.6/10 (1002) "Good location. prefer a place with a hot breakfast." £46 includes taxes & fees 2 Nov - 3 Nov [](https://www.expedia.co.uk/Columbia-Hotels-Super-8-By-Wyndham-Columbia-Clark-Lane.h459668.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/40200/40165/312544dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast ](https://images.trvl-media.com/lodging/1000000/50000/40200/40165/fc5d9ada.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Room, 2 Double Beds | Desk, free cots/infant beds, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/1000000/50000/40200/40165/fd0f7af4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/1000000/50000/40200/40165/cd10e4ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Boonville Boonville 6.4/10 (639) "Great stay" £50 includes taxes & fees 2 Nov - 3 Nov [](https://www.expedia.co.uk/Columbia-Hotels-Super-8-By-Wyndham-Boonville.h40165.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/20000/18400/18390/b506b22f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/20000/18400/18390/c69d8b68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/18400/18390/57b8a773.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Studio Suite, 1 King Bed, Non Smoking | Desk, iron/ironing board, free cots/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/18400/18390/5f892660.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Osage Beach Lake of the Ozarks Osage Beach 7.2/10 Good (1006) "Location was within walking distance of decent restaurants and easy access to the highway." £58 includes taxes & fees 9 Nov - 10 Nov [](https://www.expedia.co.uk/Osage-Beach-Hotels-Days-Inn-By-Wyndham-Osage-Beach-Lake-Of-The-Ozarks.h18390.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-29&endDate=2025-10-30®ionId=6058776&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true) ## Find out more about Central Missouri ### Central Missouriand its attractions for luxury travelers Central Missouri offers a blend of natural beauty and cultural experiences that cater perfectly to luxury travellers seeking memorable escapes. Begin your journey in the vibrant city of Columbia, home to the stunning Stephens Lake Park where you can enjoy a leisurely stroll by the shimmering waters, or rent a kayak for a unique perspective of the lush landscape. Art enthusiasts will appreciate the Columbia Art League, showcasing local talent and hosting exclusive events that provide an intimate look into the region's creative spirit. For a touch of history, visit the Missouri State Capitol in Jefferson City, where guided tours reveal stunning architecture and rich narratives of the state’s past. Adventure seekers can explore the stunning Lake of the Ozarks, where luxury resorts offer private boat rentals and serene spa experiences against a backdrop of breathtaking vistas. Finally, indulge your taste buds at the elegant restaurants in Osage Beach, where gourmet dining experiences await, featuring local produce and exquisite wines. For a truly lavish stay, consider the resorts along the Lake of the Ozarks, where you can unwind in opulent suites with panoramic lake views, enjoy world-class amenities, and receive personalised service that ensures your every need is met. This region not only promises adventure and culture but also a sophisticated atmosphere that invites you to relax and rejuvenate. ## Top Central Missouri Hotel Reviews ![Best Western Plus Columbia Inn](//images.trvl-media.com/lodging/13000000/12550000/12546300/12546284/2c317c73_y.jpg) ### Best Western Plus Columbia Inn 10/10 Excellent "Clean, staff was friendly " [](https://expedia.co.uk/Columbia-Hotels-Best-Western-Plus-Columbia-Inn.h12546284.Hotel-Information) ![Capitol Plaza Hotel Jefferson City](//images.trvl-media.com/lodging/1000000/10000/400/369/ad47cfa0_y.jpg) ### Capitol Plaza Hotel Jefferson City 10/10 Excellent "Hotel was amazing front desk staff couldn't have been better. Great weekend staff" [](https://expedia.co.uk/Columbia-Hotels-Capitol-Plaza-Hotel-Jefferson-City.h369.Hotel-Information) ![Margaritaville Lake Resort Lake of the Ozarks](//images.trvl-media.com/lodging/1000000/30000/21300/21228/268207dd_y.jpg) ### Margaritaville Lake Resort Lake of the Ozarks 10/10 Excellent "Had a wonderful time - great place to get away for the weekend " [](https://expedia.co.uk/Osage-Beach-Hotels-Margaritaville-Lake-Resort-Lake-Of-The-Ozarks.h21228.Hotel-Information) ![Baymont by Wyndham Columbia, MO](//images.trvl-media.com/lodging/1000000/50000/40200/40115/08435bc3_y.jpg) ### Baymont by Wyndham Columbia, MO 10/10 Excellent "Very clean and safe" [](https://expedia.co.uk/Columbia-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Columbia.h40115.Hotel-Information) ![Days Inn by Wyndham Rolla](//images.trvl-media.com/lodging/1000000/50000/40300/40279/1759c9c5_y.jpg) ### Days Inn by Wyndham Rolla 10/10 Excellent "I like construction, ie improvement but area is a little hard to sort out coming into parking lot. Tough for newbe’s. " [](https://expedia.co.uk/Rolla-Hotels-Days-Inn-By-Wyndham-Rolla.h40279.Hotel-Information) ![Stoney Creek Hotel Columbia](//images.trvl-media.com/lodging/2000000/1060000/1052400/1052330/5398551a_y.jpg) ### Stoney Creek Hotel Columbia 10/10 Excellent "N/A" [](https://expedia.co.uk/Columbia-Hotels-Stoney-Creek-Hotel-Columbia.h1052330.Hotel-Information) ![Lodge Of Four Seasons Golf Resort, Marina & Spa](//images.trvl-media.com/lodging/1000000/50000/40800/40728/7e36eb59_y.jpg) ### Lodge Of Four Seasons Golf Resort, Marina & Spa 10/10 Excellent "Very good hotel " [](https://expedia.co.uk/Osage-Beach-Hotels-Lodge-Of-Four-Seasons-Golf-Resort.h40728.Hotel-Information) ![Days Inn by Wyndham Osage Beach Lake of the Ozarks](//images.trvl-media.com/lodging/1000000/20000/18400/18390/b506b22f_y.jpg) ### Days Inn by Wyndham Osage Beach Lake of the Ozarks 10/10 Excellent "No issues" [](https://expedia.co.uk/Osage-Beach-Hotels-Days-Inn-By-Wyndham-Osage-Beach-Lake-Of-The-Ozarks.h18390.Hotel-Information) ## Explore a world of travel with Expedia - 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[Hotels with Gym in Missouri](https://www.expedia.co.uk/Destinations-In-Missouri-Hotel-With-Gym.0-0-d227-thotelwithgym.Hotel-Filter-Destinations) - [Hotels with Parking in Missouri](https://www.expedia.co.uk/Destinations-In-Missouri-Hotel-With-Parking.0-0-d227-thotelwithparking.Hotel-Filter-Destinations) - [Hotels with Restaurant in Missouri](https://www.expedia.co.uk/Destinations-In-Missouri-Hotel-With-Restaurant.0-0-d227-thotelwithrestaurant.Hotel-Filter-Destinations) - [Hotels with Room Service in Missouri](https://www.expedia.co.uk/Destinations-In-Missouri-Hotel-With-Room-Service.0-0-d227-thotelwithroomservice.Hotel-Filter-Destinations) - [Hotels with Hot Tubs in Missouri](https://www.expedia.co.uk/Destinations-In-Missouri-Hotels-With-Hot-Tubs.0-0-d227-tHotelsWithHotTubs.Hotel-Filter-Destinations) - [Hotels with Pool in Missouri](https://www.expedia.co.uk/Destinations-In-Missouri-Hotels-With-Pool.0-0-d227-tHotelswithPool.Hotel-Filter-Destinations) - [Hotels with smoking rooms in Missouri](https://www.expedia.co.uk/Destinations-In-Missouri-Hotels-With-Smoking-Rooms.0-0-d227-tHotelswithsmokingrooms.Hotel-Filter-Destinations) - [Lakeside Hotels in Missouri](https://www.expedia.co.uk/Destinations-In-Missouri-Lakeside-Hotel.0-0-d227-tlakesidehotel.Hotel-Filter-Destinations) - [Luxury Hotels in Missouri](https://www.expedia.co.uk/Destinations-In-Missouri-Luxury-Hotel.0-0-d227-tLuxuryHotel.Hotel-Filter-Destinations) - [Mountain Hotels in Missouri](https://www.expedia.co.uk/Destinations-In-Missouri-Mountain-Hotel.0-0-d227-tmountainhotel.Hotel-Filter-Destinations) - [Pet-Friendly Hotels in Missouri](https://www.expedia.co.uk/Destinations-In-Missouri-Pet-Friendly-Hotel.0-0-d227-tPetFriendlyHotel.Hotel-Filter-Destinations) - [Romantic Hotels in Missouri](https://www.expedia.co.uk/Destinations-In-Missouri-Romantic-Hotel.0-0-d227-tRomanticHotel.Hotel-Filter-Destinations) - [Ski Hotels in Missouri](https://www.expedia.co.uk/Destinations-In-Missouri-Ski-Hotels.0-0-d227-tSkiHotels.Hotel-Filter-Destinations) - [Spa Hotels in Missouri](https://www.expedia.co.uk/Destinations-In-Missouri-Spa-Hotels.0-0-d227-tSpaHotels.Hotel-Filter-Destinations) - 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