Title: TOP Luxury Hotels in Central Missouri, MO for 2026 - Central Missouri Upscale Hotels | Expedia.co.uk [Central Missouri Travel Guide](https://expedia.co.uk/Central-Missouri.dx6058776)[Hotels in Central Missouri](https://expedia.co.uk/Central-Missouri-Hotels.d6058776.Travel-Guide-Hotels)[Holiday Rentals in Central Missouri](https://expedia.co.uk/Central-Missouri-Holiday-Rentals.d6058776.Travel-Guide-HolidayRentals)[Flights to Central Missouri](https://expedia.co.uk/Cheap-Flights-To-Central-Missouri.d6058776.Travel-Guide-Flights)[Things to do in Central Missouri](https://expedia.co.uk/Things-To-Do-In-Central-Missouri.d6058776.Travel-Guide-Activities)[Central Missouri Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Central-Missouri.d6058776.Car-Hire-Guide)[Central Missouri Holidays](https://expedia.co.uk/Central-Missouri.d6058776.Holidays-City-Breaks) ![Missouri State Capitol which includes an administrative building, a fountain and heritage architecture](https://images.trvl-media.com/place/6092643/f7036169-7e6d-403b-b3a3-fac711433497.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6092643/f7036169-7e6d-403b-b3a3-fac711433497.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Central Missouri Luxury Hotels Tonight [14 Jan - 15 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6058776&startDate=2026-01-14&endDate=2026-01-15&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Tomorrow [15 Jan - 16 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6058776&startDate=2026-01-15&endDate=2026-01-16&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) This weekend [16 Jan - 18 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6058776&startDate=2026-01-16&endDate=2026-01-18&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) Next weekend [23 Jan - 25 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6058776&startDate=2026-01-23&endDate=2026-01-25&adults=2&propertyStyle=LUXURY&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=luxury_property) ## Our top choices for Central Missouri luxury hotels ![Studio Suite, 1 King Bed, Non Smoking | Desk, iron/ironing board, free cots/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/18900/18803/2c2e5fb9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/20000/18900/18803/87337ebd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/20000/18900/18803/7ea5455a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Studio Suite, 1 King Bed with Sofa bed, Non Smoking | Desk, iron/ironing board, free cots/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/18900/18803/6a34339a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ramada by Wyndham Columbia [](https://www.expedia.co.uk/Columbia-Hotels-Ramada-By-Wyndham-Columbia.h18803.Hotel-Information) Columbia 7.6/10 Good (1,000 reviews) "Decent room for the price point " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) William £50 includes taxes & fees 2 Feb - 3 Feb [](https://www.expedia.co.uk/Columbia-Hotels-Ramada-By-Wyndham-Columbia.h18803.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/5000000/4800000/4790100/4790037/17a25a6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4800000/4790100/4790037/470645a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4800000/4790100/4790037/5f1d172a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 restaurants, breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/5000000/4800000/4790100/4790037/ae9109fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### voco The Tiger Hotel Columbia, MO by IHG [](https://www.expedia.co.uk/Columbia-Hotels-The-Tiger-Hotel.h4790037.Hotel-Information) Columbia 9.0/10 Wonderful (1,002 reviews) "Staff was extremely friendly and helpful. Room was spotless and comfortable. We ate at Glenns Cafe and it was amazing. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Pam £133 includes taxes & fees 15 Feb - 16 Feb [](https://www.expedia.co.uk/Columbia-Hotels-The-Tiger-Hotel.h4790037.Hotel-Information) ![Poolside bar](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/a2724c85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/7e36eb59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/7a41768f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/d106f50c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lodge Of Four Seasons Golf Resort, Marina & Spa [](https://www.expedia.co.uk/Osage-Beach-Hotels-Lodge-Of-Four-Seasons-Golf-Resort.h40728.Hotel-Information) Lake Ozark 7.4/10 Good (1,099 reviews) "This is a wonderful hotel to stay. They have wonderful views and great space to relax. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Renee £99 includes taxes & fees 16 Jan - 17 Jan [](https://www.expedia.co.uk/Osage-Beach-Hotels-Lodge-Of-Four-Seasons-Golf-Resort.h40728.Hotel-Information) ![Aerial view](https://images.trvl-media.com/lodging/3000000/2020000/2015400/2015357/ecd45695.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property – evening/night](https://images.trvl-media.com/lodging/3000000/2020000/2015400/2015357/3ff758b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch, dinner served; Caribbean cuisine ](https://images.trvl-media.com/lodging/3000000/2020000/2015400/2015357/81f164d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, pool loungers](https://images.trvl-media.com/lodging/3000000/2020000/2015400/2015357/61a3503e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Camden on the Lake Resort & Spa [](https://www.expedia.co.uk/Osage-Beach-Hotels-Camden-On-The-Lake-Resort-Spa.h2015357.Hotel-Information) Lake Ozark 9.0/10 Wonderful (1,000 reviews) "Great stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Daniel [](https://www.expedia.co.uk/Osage-Beach-Hotels-Camden-On-The-Lake-Resort-Spa.h2015357.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/800000/794300/794290/22e30a85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/1000000/800000/794300/794290/5302832b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/800000/794300/794290/f26bf08a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillow-top beds, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/800000/794300/794290/16c08a6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Bothwell Sedalia Central District, an Ascend Collection Hotel [](https://www.expedia.co.uk/Clinton-Hotels-Hotel-Bothwell-Sedalia-Central-District.h794290.Hotel-Information) Sedalia Downtown Historic District 9.2/10 Wonderful (585 reviews) "Great place. Beautifully decorated for the season. Great staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Leah £89 includes taxes & fees 14 Feb - 15 Feb [](https://www.expedia.co.uk/Clinton-Hotels-Hotel-Bothwell-Sedalia-Central-District.h794290.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/8000000/7770000/7768600/7768577/f96db8bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/8000000/7770000/7768600/7768577/c053648f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/8000000/7770000/7768600/7768577/579bc607.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/8000000/7770000/7768600/7768577/350205ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Laci's Country Inn [](https://www.expedia.co.uk/Clinton-Hotels-Lacis-Country-Inn.h7768577.Hotel-Information) Knob Noster 7.0/10 Good (162 reviews) "Room was super clean, spacious, and comfy bed. Great staff, fast wifi. Restaurant across the street. Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Janet Sison £50 includes taxes & fees 13 Feb - 14 Feb [](https://www.expedia.co.uk/Clinton-Hotels-Lacis-Country-Inn.h7768577.Hotel-Information) ![Free daily full breakfast ](https://images.trvl-media.com/lodging/13000000/12550000/12546300/12546284/89f564da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/13000000/12550000/12546300/12546284/bc9612c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/13000000/12550000/12546300/12546284/e7c009b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/13000000/12550000/12546300/12546284/2c317c73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Columbia Inn [](https://www.expedia.co.uk/Columbia-Hotels-Best-Western-Plus-Columbia-Inn.h12546284.Hotel-Information) Columbia 9.0/10 Wonderful (1,217 reviews) "Check in was easy. Request for extra blanket was honored." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Isaiah £59 includes taxes & fees 18 Jan - 19 Jan [](https://www.expedia.co.uk/Columbia-Hotels-Best-Western-Plus-Columbia-Inn.h12546284.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/460000/459700/459668/52bc64ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/460000/459700/459668/184a1306.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout curtains, free WiFi](https://images.trvl-media.com/lodging/1000000/460000/459700/459668/e11b82f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed | Desk, laptop workspace, blackout curtains, free WiFi](https://images.trvl-media.com/lodging/1000000/460000/459700/459668/a99e46d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Columbia Clark Lane [](https://www.expedia.co.uk/Columbia-Hotels-Super-8-By-Wyndham-Columbia-Clark-Lane.h459668.Hotel-Information) Columbia 6.6/10 (1,001 reviews) "Good hotel for the money." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Katie £44 includes taxes & fees 28 Jan - 29 Jan [](https://www.expedia.co.uk/Columbia-Hotels-Super-8-By-Wyndham-Columbia-Clark-Lane.h459668.Hotel-Information) ![Studio Suite, 1 Queen Bed, Non Smoking | Desk, free cots/infant beds, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/1000000/50000/40200/40165/01e1d362.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/40200/40165/312544dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Studio Suite, 1 King Bed, Non Smoking | Desk, free cots/infant beds, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/1000000/50000/40200/40165/w3000h1872x0y128-643a5db7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast ](https://images.trvl-media.com/lodging/1000000/50000/40200/40165/fc5d9ada.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Boonville [](https://www.expedia.co.uk/Columbia-Hotels-Super-8-By-Wyndham-Boonville.h40165.Hotel-Information) Boonville 6.4/10 (653 reviews) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Bradley £52 includes taxes & fees 15 Feb - 16 Feb [](https://www.expedia.co.uk/Columbia-Hotels-Super-8-By-Wyndham-Boonville.h40165.Hotel-Information) ![Room, 2 Queen Beds, Non Smoking | Desk, iron/ironing board, free cots/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/18400/18390/d87275eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast ](https://images.trvl-media.com/lodging/1000000/20000/18400/18390/b0575db1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/18400/18390/57b8a773.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/20000/18400/18390/c69d8b68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Osage Beach Lake of the Ozarks [](https://www.expedia.co.uk/Osage-Beach-Hotels-Days-Inn-By-Wyndham-Osage-Beach-Lake-Of-The-Ozarks.h18390.Hotel-Information) Osage Beach 7.2/10 Good (1,001 reviews) "Friendly efficient check-in. Pleasant room. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anna £47 includes taxes & fees 19 Jan - 20 Jan [](https://www.expedia.co.uk/Osage-Beach-Hotels-Days-Inn-By-Wyndham-Osage-Beach-Lake-Of-The-Ozarks.h18390.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-29&endDate=2026-01-30®ionId=6058776&adults=2&star=50&sort=RECOMMENDED&openPlayBack=true) ## Find out more about Central Missouri ### Central Missouriand its attractions for luxury travelers Central Missouri offers a blend of natural beauty and cultural experiences that cater perfectly to luxury travellers seeking memorable escapes. Begin your journey in the vibrant city of Columbia, home to the stunning Stephens Lake Park where you can enjoy a leisurely stroll by the shimmering waters, or rent a kayak for a unique perspective of the lush landscape. Art enthusiasts will appreciate the Columbia Art League, showcasing local talent and hosting exclusive events that provide an intimate look into the region's creative spirit. For a touch of history, visit the Missouri State Capitol in Jefferson City, where guided tours reveal stunning architecture and rich narratives of the state’s past. Adventure seekers can explore the stunning Lake of the Ozarks, where luxury resorts offer private boat rentals and serene spa experiences against a backdrop of breathtaking vistas. Finally, indulge your taste buds at the elegant restaurants in Osage Beach, where gourmet dining experiences await, featuring local produce and exquisite wines. For a truly lavish stay, consider the resorts along the Lake of the Ozarks, where you can unwind in opulent suites with panoramic lake views, enjoy world-class amenities, and receive personalised service that ensures your every need is met. This region not only promises adventure and culture but also a sophisticated atmosphere that invites you to relax and rejuvenate. ## Top Central Missouri Hotel Reviews ![Stoney Creek Hotel Columbia](https://images.trvl-media.com/lodging/2000000/1060000/1052400/1052330/5398551a_y.jpg) ### Stoney Creek Hotel Columbia 10/10 Excellent "Great staff" [](https://expedia.co.uk/Columbia-Hotels-Stoney-Creek-Hotel-Columbia.h1052330.Hotel-Information) ![Hampton Inn & Suites Columbia at University](https://images.trvl-media.com/lodging/3000000/2010000/2009600/2009513/2702d693_y.jpg) ### Hampton Inn & Suites Columbia at University 10/10 Excellent "Room was excellent, staff was nice!! Bed was hard but everything else was great!!!" [](https://expedia.co.uk/Columbia-Hotels-Hampton-Inn-Suites-Columbia-At-University.h2009513.Hotel-Information) ![Baymont by Wyndham Columbia, MO](https://images.trvl-media.com/lodging/1000000/50000/40200/40115/08435bc3_y.jpg) ### Baymont by Wyndham Columbia, MO 10/10 Excellent "Clean room. Good healthy breakfast options. Safe parking. Friendly staff." [](https://expedia.co.uk/Columbia-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Columbia.h40115.Hotel-Information) ![Best Western Plus Columbia Inn](https://images.trvl-media.com/lodging/13000000/12550000/12546300/12546284/2c317c73_y.jpg) ### Best Western Plus Columbia Inn 10/10 Excellent "Clean room. Staff was helpful. The toilet was clogged and they fixed it quickly. Breakfast was solid. " [](https://expedia.co.uk/Columbia-Hotels-Best-Western-Plus-Columbia-Inn.h12546284.Hotel-Information) ![Lodge Of Four Seasons Golf Resort, Marina & Spa](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/7e36eb59_y.jpg) ### Lodge Of Four Seasons Golf Resort, Marina & Spa 10/10 Excellent "Really fun property with lots of trails. Really great staff. Love the sunken living room / conversation pit. " [](https://expedia.co.uk/Osage-Beach-Hotels-Lodge-Of-Four-Seasons-Golf-Resort.h40728.Hotel-Information) ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - More ways to book - [Apache Flats Hotels ](https://www.expedia.co.uk/Apache-Flats-Hotels.d553248635975850469.Travel-Guide-Hotels) - [Hotels near California Country Club ](https://www.expedia.co.uk/California-Country-Club-Hotels.0-l553248621594455013-0.Travel-Guide-Filter-Hotels) - [California Hotels ](https://www.expedia.co.uk/California-Hotels.d6351831.Travel-Guide-Hotels) - [Adults Only Resorts & in Missouri ](https://www.expedia.co.uk/Destinations-In-Missouri-Adults-Only-Resorts.0-0-d227-tAdultsOnlyResorts.Hotel-Filter-Destinations) - [All-Inclusive Hotels in Missouri ](https://www.expedia.co.uk/Destinations-In-Missouri-All-Inclusive-Hotel.0-0-d227-tAllInclusiveHotel.Hotel-Filter-Destinations) - [Beach Resorts & in Missouri ](https://www.expedia.co.uk/Destinations-In-Missouri-Beach-Hotels.0-0-d227-tBeachHotels.Hotel-Filter-Destinations) - 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