Title: TOP Business Hotels in Central Missouri, MO for 2025 | Expedia.co.uk [Central Missouri Travel Guide](https://expedia.co.uk/Central-Missouri.dx6058776)[Hotels in Central Missouri](https://expedia.co.uk/Central-Missouri-Hotels.d6058776.Travel-Guide-Hotels)[Holiday Rentals in Central Missouri](https://expedia.co.uk/Central-Missouri-Holiday-Rentals.d6058776.Travel-Guide-HolidayRentals)[Flights to Central Missouri](https://expedia.co.uk/Cheap-Flights-To-Central-Missouri.d6058776.Travel-Guide-Flights)[Things to do in Central Missouri](https://expedia.co.uk/Things-To-Do-In-Central-Missouri.d6058776.Travel-Guide-Activities)[Central Missouri Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Central-Missouri.d6058776.Car-Hire-Guide)[Central Missouri Holidays](https://expedia.co.uk/Central-Missouri.d6058776.Holidays-City-Breaks) ![Columbia showing wild flowers](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/257000/257714-Central-Missouri.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Business Hotels in Central Missouri ![price find illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Central Missouri Business Hotels Tonight [20 Sept - 21 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=6058776&startDate=2025-09-20&endDate=2025-09-21&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [21 Sept - 22 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=6058776&startDate=2025-09-21&endDate=2025-09-22&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [26 Sept - 28 Sept](https://www.expedia.co.uk/Hotel-Search?regionId=6058776&startDate=2025-09-26&endDate=2025-09-28&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [3 Oct - 5 Oct](https://www.expedia.co.uk/Hotel-Search?regionId=6058776&startDate=2025-10-03&endDate=2025-10-05&adults=2&travelerType=BUSINESS&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Central Missouri Business Hotels ## Our top choices for Central Missouri business-friendly hotels ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/22400/22359/86998653.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/30000/22400/22359/16b33223.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Multiple Beds, Non Smoking | Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/30000/22400/22359/892627b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gym](https://images.trvl-media.com/lodging/1000000/30000/22400/22359/ea852bf5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wyndham Executive Center Columbia Columbia 8.4/10 Very good (1015) "Nice, clean room and very friendly a d helpful staff." £69 includes taxes & fees 21 Sept - 22 Sept [](https://www.expedia.co.uk/Columbia-Hotels-Holiday-Inn-Executive-Center-Columbia-Mall.h22359.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42200/42129/3e728377.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout curtains, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/1000000/50000/42200/42129/a7c5548b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/42200/42129/33542641.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42200/42129/5d0aa8c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Columbia Stadium Boulevard Columbia 9.4/10 Exceptional (1010) "Would stay again." £79 includes taxes & fees 28 Sept - 29 Sept [](https://www.expedia.co.uk/Columbia-Hotels-Drury-Inn-Suites-Columbia-Stadium-Boulevard.h42129.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/990000/986100/986086/a16387a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/990000/986100/986086/e142bb33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/990000/986100/986086/ea622913.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, pillow-top beds, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/990000/986100/986086/e5aec7bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wingate by Wyndham - Columbia Columbia 9.0/10 Wonderful (1168) "Very nice place to stay" £77 includes taxes & fees 28 Sept - 29 Sept [](https://www.expedia.co.uk/Columbia-Hotels-Wingate-By-Wyndham-Columbia.h986086.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/13000000/12550000/12546300/12546284/2c317c73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/13000000/12550000/12546300/12546284/c428cb4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/13000000/12550000/12546300/12546284/bd7f5440.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/13000000/12550000/12546300/12546284/805c2520.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Columbia Inn Columbia 8.8/10 Excellent (1188) "Great place to stay! " £60 includes taxes & fees 14 Oct - 15 Oct [](https://www.expedia.co.uk/Columbia-Hotels-Best-Western-Plus-Columbia-Inn.h12546284.Hotel-Information) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/83000000/82910000/82907900/82907804/3208717a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Double Room, 2 Queen Beds | In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/83000000/82910000/82907900/82907804/416d9696.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Concierge desk](https://images.trvl-media.com/lodging/83000000/82910000/82907900/82907804/52f4cae4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/83000000/82910000/82907900/82907804/8524f890.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Schmidt's Creek Hotel Osage Beach 8.8/10 Excellent (400) "The staff is very friendly and helpful check in went seamlessly I had 3 rooms reserved. The rooms were very clean with nice beds linens and towels. I would definitely stay here again" [](https://www.expedia.co.uk/Osage-Beach-Hotels-Schmidts-Creek-Hotel.h82907804.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1660000/1658500/1658463/c8809092.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, desk, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1660000/1658500/1658463/4cbd87ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free continental breakfast ](https://images.trvl-media.com/lodging/2000000/1660000/1658500/1658463/bdb28afc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1660000/1658500/1658463/w2870h1920x0y0-23ef12fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Inn & Suites by Radisson, Columbia, MO Columbia 9.0/10 Wonderful (1627) "Nice place to stay " £69 includes taxes & fees 5 Oct - 6 Oct [](https://www.expedia.co.uk/Columbia-Hotels-Country-Inn-Suites-By-Radisson.h1658463.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/22000000/21390000/21389900/21389857/f3ce0b31.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/22000000/21390000/21389900/21389857/d8249250.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/22000000/21390000/21389900/21389857/feeda94e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/22000000/21390000/21389900/21389857/b950bc23.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Plaza Hotel Columbia East Columbia 9.6/10 Exceptional (1279) "I would happily stay there again" £81 includes taxes & fees 30 Sept - 1 Oct [](https://www.expedia.co.uk/Columbia-Hotels-Drury-Plaza-Hotel-Columbia-East.h21389857.Hotel-Information) ![Studio Suite, 1 King Bed, Non Smoking | Desk, iron/ironing board, free cots/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/18900/18803/77d8da33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/1000000/20000/18900/18803/7ea5455a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/18900/18803/0abef2e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/18900/18803/8a965f77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ramada by Wyndham Columbia Columbia 7.4/10 Good (1012) "A very nice, quiet, restful stay" £53 includes taxes & fees 28 Sept - 29 Sept [](https://www.expedia.co.uk/Columbia-Hotels-Ramada-By-Wyndham-Columbia.h18803.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/10000000/9320000/9312500/9312411/0f1fe689.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/10000000/9320000/9312500/9312411/9d92a9a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/10000000/9320000/9312500/9312411/3a09893f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/10000000/9320000/9312500/9312411/80a58293.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Candlewood Suites Columbia East by IHG Columbia 9.0/10 Wonderful (620) "great clean hotel" £95 includes taxes & fees 28 Sept - 29 Sept [](https://www.expedia.co.uk/Columbia-Hotels-Candlewood-Suites-Columbia-East.h9312411.Hotel-Information) ![Desk, blackout curtains, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/1000000/970000/969800/969753/7942efa9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout curtains, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/1000000/970000/969800/969753/83e135fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Snack bar](https://images.trvl-media.com/lodging/1000000/970000/969800/969753/734c3da8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/970000/969800/969753/203d4685.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Ft. Leonard/Saint Robert St. Robert 9.0/10 Wonderful (1009) "The hotel location was very convenient. Staff were very friendly." £81 includes taxes & fees 27 Sept - 28 Sept [](https://www.expedia.co.uk/Rolla-Hotels-Baymont-By-Wyndham-Ft-LeonardSaint-Robert.h969753.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-10-04&endDate=2025-10-05®ionId=6058776&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Central Missouri Hotel Reviews ![Inn at Grand Glaize](//images.trvl-media.com/lodging/1000000/70000/60700/60685/a0b4c124_y.jpg) ### Inn at Grand Glaize 10/10 Excellent "I love the lake view you get from the room" [](https://expedia.co.uk/Osage-Beach-Hotels-Inn-At-Grand-Glaize.h60685.Hotel-Information) ![Baymont by Wyndham Columbia, MO](//images.trvl-media.com/lodging/1000000/50000/40200/40115/08435bc3_y.jpg) ### Baymont by Wyndham Columbia, MO 10/10 Excellent "Very reasonable " [](https://expedia.co.uk/Columbia-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Columbia.h40115.Hotel-Information) ![Best Western Plus Columbia Inn](//images.trvl-media.com/lodging/13000000/12550000/12546300/12546284/2c317c73_y.jpg) ### Best Western Plus Columbia Inn 10/10 Excellent "Friendly staff, quick check in, clean rooms! " [](https://expedia.co.uk/Columbia-Hotels-Best-Western-Plus-Columbia-Inn.h12546284.Hotel-Information) ![Country Inn & Suites by Radisson, Columbia, MO](//images.trvl-media.com/lodging/2000000/1660000/1658500/1658463/c8809092_y.jpg) ### Country Inn & Suites by Radisson, Columbia, MO 10/10 Excellent "Clean and comfortable. Friendly staff. Would stay there again. Bed comfortable. " [](https://expedia.co.uk/Columbia-Hotels-Country-Inn-Suites-By-Radisson.h1658463.Hotel-Information) ![Stoney Creek Hotel Columbia](//images.trvl-media.com/lodging/2000000/1060000/1052400/1052330/5398551a_y.jpg) ### Stoney Creek Hotel Columbia 10/10 Excellent "Room nice and clean. Staff great! And love the atmosphere " [](https://expedia.co.uk/Columbia-Hotels-Stoney-Creek-Hotel-Columbia.h1052330.Hotel-Information) ![Drury Inn & Suites Columbia Stadium Boulevard](//images.trvl-media.com/lodging/1000000/50000/42200/42129/3e728377_y.jpg) ### Drury Inn & Suites Columbia Stadium Boulevard 10/10 Excellent "Front desk Staff was amazing, so kind, positive and helpful! Beds were comfortable and coffee was good!" [](https://expedia.co.uk/Columbia-Hotels-Drury-Inn-Suites-Columbia-Stadium-Boulevard.h42129.Hotel-Information) ![Wingate by Wyndham - Columbia](//images.trvl-media.com/lodging/1000000/990000/986100/986086/a16387a6_y.jpg) ### Wingate by Wyndham - Columbia 10/10 Excellent "We only stayed one night. Ryan, the manager, was so nice after I messed up the reservation. The hotel was very accommodating. There's a lot of road noise, but it did not prevent us from getting a good night's sleep. Would stay here again." [](https://expedia.co.uk/Columbia-Hotels-Wingate-By-Wyndham-Columbia.h986086.Hotel-Information) ![Osage Village Inn](//images.trvl-media.com/lodging/15000000/14840000/14832000/14831964/w2421h2876x0y0-0a3c5da2_y.jpg) ### Osage Village Inn 10/10 Excellent "We left after 20 minutes at the property due to the smell of the room. It wasnt clean. Found bugs on the sheets." [](https://expedia.co.uk/Osage-Beach-Hotels-Osage-Village-Inn.h14831964.Hotel-Information) ![Margaritaville Lake Resort Lake of the Ozarks](//images.trvl-media.com/lodging/1000000/30000/21300/21228/268207dd_y.jpg) ### Margaritaville Lake Resort Lake of the Ozarks 10/10 Excellent "On a busy weekend staff was super helpful" [](https://expedia.co.uk/Osage-Beach-Hotels-Margaritaville-Lake-Resort-Lake-Of-The-Ozarks.h21228.Hotel-Information) ## Frequently asked questions ### How much do business hotels in Central Missouri cost? > You can expect to pay between and per night for business hotels in Central Missouri. Top deals on properties that cater to people travelling for work are a click away on Expedia. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply. ### How many business hotels are there in Central Missouri? > Central Missouri has business hotels to pick from. Whether you're catching up with clients or working remotely, these stays come with the amenities you need to keep you productive and comfortable. ### Why book your business hotel in Central Missouri with Expedia? > With amenities like meeting rooms, housekeeping and on-site restaurants, our business hotels come with all you'll need to settle your important deal — and then put your feet up! Enter your travel destination and preferred dates and we'll help you plan everything else. ### How can I find cheap business hotels in Central Missouri? > Expedia can help you easily find cheap business hotels in Central Missouri. Simply go to our "traveller experience" filter and click on "business friendly." This will show you stays with amenities designed to help you work comfortably and effectively, like free WiFi and included breakfast. 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