Title: TOP Business Hotels in Central Missouri, MO for 2025 | Expedia.co.uk [Central Missouri Travel Guide](https://expedia.co.uk/Central-Missouri.dx6058776)[Hotels in Central Missouri](https://expedia.co.uk/Central-Missouri-Hotels.d6058776.Travel-Guide-Hotels)[Holiday Rentals in Central Missouri](https://expedia.co.uk/Central-Missouri-Holiday-Rentals.d6058776.Travel-Guide-HolidayRentals)[Flights to Central Missouri](https://expedia.co.uk/Cheap-Flights-To-Central-Missouri.d6058776.Travel-Guide-Flights)[Things to do in Central Missouri](https://expedia.co.uk/Things-To-Do-In-Central-Missouri.d6058776.Travel-Guide-Activities)[Central Missouri Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Central-Missouri.d6058776.Car-Hire-Guide)[Central Missouri Holidays](https://expedia.co.uk/Central-Missouri.d6058776.Holidays-City-Breaks) ![University of Missouri which includes heritage architecture, a garden and street scenes](https://images.trvl-media.com/place/6093455/6cff96be-1e29-4df3-85b4-5c4b939de401.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Business Hotels in Central Missouri - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Central Missouri Business Hotels Tonight [6 Nov - 7 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6058776&startDate=2025-11-06&endDate=2025-11-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [7 Nov - 8 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6058776&startDate=2025-11-07&endDate=2025-11-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [7 Nov - 9 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6058776&startDate=2025-11-07&endDate=2025-11-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [14 Nov - 16 Nov](https://www.expedia.co.uk/Hotel-Search?regionId=6058776&startDate=2025-11-14&endDate=2025-11-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Top Central Missouri Business Hotels ![Front of property](https://images.trvl-media.com/lodging/16000000/15490000/15487700/15487684/4071c448.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/16000000/15490000/15487700/15487684/136440e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Children’s play area – outdoor](https://images.trvl-media.com/lodging/16000000/15490000/15487700/15487684/104061b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/16000000/15490000/15487700/15487684/0c1d1e5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Echo Bluff State Park Eminence 9.4/10 Exceptional (212) "Beautiful location & very friendly staff!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Becky £118 includes taxes & fees 13 Nov - 14 Nov [](https://www.expedia.co.uk/Rolla-Hotels-Echo-Bluff-State-Park.h15487684.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/13000000/12550000/12546300/12546284/2c317c73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Room, 1 King Bed, Non Smoking, Refrigerator & Microwave | Down duvets, pillow-top beds, desk, blackout curtains](https://images.trvl-media.com/lodging/13000000/12550000/12546300/12546284/fd258818.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/13000000/12550000/12546300/12546284/bd7f5440.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/13000000/12550000/12546300/12546284/805c2520.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Columbia Inn Columbia 8.8/10 Excellent (1194) "Stayed here several times and was very happy with our stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Reynaldo £62 includes taxes & fees 18 Nov - 19 Nov [](https://www.expedia.co.uk/Columbia-Hotels-Best-Western-Plus-Columbia-Inn.h12546284.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/890000/882800/882709/74a00d2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/890000/882800/882709/e6a5e156.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/890000/882800/882709/4f600580.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/890000/882800/882709/13784ba7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sleep Inn & Suites Lake of the Ozarks Camdenton 8.8/10 Excellent (970) "Great room, great breakfast, great price" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kent £92 includes taxes & fees 7 Dec - 8 Dec [](https://www.expedia.co.uk/Osage-Beach-Hotels-Sleep-Inn-Suites-Lake-Of-The-Ozarks.h882709.Hotel-Information) ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/22000000/21390000/21389900/21389857/3abac008.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/22000000/21390000/21389900/21389857/adf569fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/22000000/21390000/21389900/21389857/30aeb622.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, laptop workspace, blackout curtains](https://images.trvl-media.com/lodging/22000000/21390000/21389900/21389857/d9d4349f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Plaza Hotel Columbia East Columbia 9.6/10 Exceptional (1289) "Great stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Adam £81 includes taxes & fees 16 Nov - 17 Nov [](https://www.expedia.co.uk/Columbia-Hotels-Drury-Plaza-Hotel-Columbia-East.h21389857.Hotel-Information) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/800000/794300/794290/1e51ead0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillow-top beds, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/800000/794300/794290/8bf18cbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/800000/794300/794290/8ad6955b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/1000000/800000/794300/794290/5302832b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Bothwell Sedalia Central District, an Ascend Collection Hotel Sedalia Downtown Historic District 9.2/10 Wonderful (568) "Fun stay in a historical building." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nathaniel £97 includes taxes & fees 30 Nov - 1 Dec [](https://www.expedia.co.uk/Clinton-Hotels-Hotel-Bothwell-Sedalia-Central-District.h794290.Hotel-Information) ![Casino](https://images.trvl-media.com/lodging/10000000/9750000/9747200/9747129/d7688c2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/10000000/9750000/9747200/9747129/8976c793.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/10000000/9750000/9747200/9747129/0c19f127.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/10000000/9750000/9747200/9747129/ebf5de16.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Isle of Capri Casino Hotel Boonville - A Caesars Rewards Destination Boonville 8.2/10 Very good (911) "Room was clean. Staff was friendly. Only issue was that for those staying more than one day you had to request housecleaning to get fresh towels and clean the room. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mark £75 includes taxes & fees 13 Nov - 14 Nov [](https://www.expedia.co.uk/Columbia-Hotels-Isle-Of-Capri-Casino-Hotel-Boonville.h9747129.Hotel-Information) ![Free buffet breakfast ](https://images.trvl-media.com/lodging/3000000/2080000/2076200/2076200/6ef0f52f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2080000/2076200/2076200/cf503102.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/3000000/2080000/2076200/2076200/a2ca09b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/3000000/2080000/2076200/2076200/c9f08f83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Sedalia by IHG Sedalia 9.2/10 Wonderful (586) "Front desk staff was very helpful and friendly. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gary £80 includes taxes & fees 29 Nov - 30 Nov [](https://www.expedia.co.uk/Clinton-Hotels-Holiday-Inn-Express-Suites-Sedalia.h2076200.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/7e36eb59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/d106f50c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![5 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/40992baf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/7a41768f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lodge Of Four Seasons Golf Resort, Marina & Spa Lake Ozark 7.4/10 Good (1057) "Nice place. Good parking and convenient location to restaurants. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Daryla £81 includes taxes & fees 3 Dec - 4 Dec [](https://www.expedia.co.uk/Osage-Beach-Hotels-Lodge-Of-Four-Seasons-Golf-Resort.h40728.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1330000/1328700/1328698/a54e6ce3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/2000000/1330000/1328700/1328698/57a2f2e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, soundproofing, iron/ironing board, cots/infant beds](https://images.trvl-media.com/lodging/2000000/1330000/1328700/1328698/bfbef8a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1330000/1328700/1328698/d6dce786.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Parkfield Inn Clinton 9.2/10 Wonderful (954) "Friendliest staff, quick elevator, cleanest sheets and bathroom! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Angie R £82 includes taxes & fees 13 Nov - 14 Nov [](https://www.expedia.co.uk/Clinton-Hotels-Parkfield-Inn.h1328698.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1660000/1658500/1658463/c8809092.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free continental breakfast ](https://images.trvl-media.com/lodging/2000000/1660000/1658500/1658463/bdb28afc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1660000/1658500/1658463/w2870h1920x0y0-23ef12fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1660000/1658500/1658463/ebcde04c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Inn & Suites by Radisson, Columbia, MO Columbia 9.0/10 Wonderful (1650) "The room was very clean, the staff was friendly and the breakfast was great." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Berniece £72 includes taxes & fees 23 Nov - 24 Nov [](https://www.expedia.co.uk/Columbia-Hotels-Country-Inn-Suites-By-Radisson.h1658463.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2025-11-20&endDate=2025-11-21®ionId=6058776&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Central Missouri Hotel Reviews ## Frequently asked questions ### How much do business hotels in Central Missouri cost? > You can expect to pay between and per night for business hotels in Central Missouri. Top deals on properties that cater to people travelling for work are a click away on Expedia. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply. ### How many business hotels are there in Central Missouri? > Central Missouri has business hotels to pick from. Whether you're catching up with clients or working remotely, these stays come with the amenities you need to keep you productive and comfortable. ### Why book your business hotel in Central Missouri with Expedia? > With amenities like meeting rooms, housekeeping and on-site restaurants, our business hotels come with all you'll need to settle your important deal — and then put your feet up! Enter your travel destination and preferred dates and we'll help you plan everything else. ### How can I find cheap business hotels in Central Missouri? > Expedia can help you easily find cheap business hotels in Central Missouri. Simply go to our "traveller experience" filter and click on "business friendly." This will show you stays with amenities designed to help you work comfortably and effectively, like free WiFi and included breakfast. 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