Title: TOP Business Hotels in Central Missouri, MO for 2026 | Expedia.co.uk [Central Missouri Travel Guide](https://expedia.co.uk/Central-Missouri.dx6058776)[Hotels in Central Missouri](https://expedia.co.uk/Central-Missouri-Hotels.d6058776.Travel-Guide-Hotels)[Holiday Rentals in Central Missouri](https://expedia.co.uk/Central-Missouri-Holiday-Rentals.d6058776.Travel-Guide-HolidayRentals)[Flights to Central Missouri](https://expedia.co.uk/Cheap-Flights-To-Central-Missouri.d6058776.Travel-Guide-Flights)[Things to do in Central Missouri](https://expedia.co.uk/Things-To-Do-In-Central-Missouri.d6058776.Travel-Guide-Activities)[Central Missouri Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Central-Missouri.d6058776.Car-Hire-Guide)[Central Missouri Holidays](https://expedia.co.uk/Central-Missouri.d6058776.Holidays-City-Breaks) ![Missouri State Capitol which includes an administrative building, a fountain and heritage architecture](https://images.trvl-media.com/place/6092643/f7036169-7e6d-403b-b3a3-fac711433497.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Search Business Hotels in Central Missouri - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Central Missouri Business Hotels Tonight [22 Dec - 23 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6058776&startDate=2025-12-22&endDate=2025-12-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [23 Dec - 24 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6058776&startDate=2025-12-23&endDate=2025-12-24&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [26 Dec - 28 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6058776&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [2 Jan - 4 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6058776&startDate=2026-01-02&endDate=2026-01-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Central Missouri business-friendly hotels ![Front of property](https://images.trvl-media.com/lodging/16000000/15490000/15487700/15487684/2025663e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/16000000/15490000/15487700/15487684/ca85d578.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/16000000/15490000/15487700/15487684/0c1d1e5e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor wedding area](https://images.trvl-media.com/lodging/16000000/15490000/15487700/15487684/d46ce6e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Echo Bluff State Park [](https://www.expedia.co.uk/Rolla-Hotels-Echo-Bluff-State-Park.h15487684.Hotel-Information) Eminence 9.6/10 Exceptional (217) "The cabin was beautiful, comfy, & private! The park was FANTASTIC for hiking & scenery! We hope to return and maybe bring family or friends. The staff were all friendly too! :)" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joanne £119 includes taxes & fees 25 Dec - 26 Dec [](https://www.expedia.co.uk/Rolla-Hotels-Echo-Bluff-State-Park.h15487684.Hotel-Information) ![Poolside bar](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/a2724c85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/7a41768f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/d106f50c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/7e36eb59.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lodge Of Four Seasons Golf Resort, Marina & Spa [](https://www.expedia.co.uk/Osage-Beach-Hotels-Lodge-Of-Four-Seasons-Golf-Resort.h40728.Hotel-Information) Lake Ozark 7.4/10 Good (1085) "Great Stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karen £80 includes taxes & fees 12 Jan - 13 Jan 2026 [](https://www.expedia.co.uk/Osage-Beach-Hotels-Lodge-Of-Four-Seasons-Golf-Resort.h40728.Hotel-Information) ![Suite, Multiple Beds, Non Smoking | Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/30000/22400/22359/9c49804e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/22400/22359/86998653.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Multiple Beds, Non Smoking | Desk, laptop workspace, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/30000/22400/22359/84b12da6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/30000/22400/22359/b457c7e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wyndham Executive Center Columbia [](https://www.expedia.co.uk/Columbia-Hotels-Holiday-Inn-Executive-Center-Columbia-Mall.h22359.Hotel-Information) Columbia 8.4/10 Very good (1002) "Spotless room, friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kent £78 includes taxes & fees 2 Jan - 3 Jan 2026 [](https://www.expedia.co.uk/Columbia-Hotels-Holiday-Inn-Executive-Center-Columbia-Mall.h22359.Hotel-Information) ![Casino](https://images.trvl-media.com/lodging/10000000/9750000/9747200/9747129/d7688c2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/10000000/9750000/9747200/9747129/43717afc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/10000000/9750000/9747200/9747129/8976c793.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/10000000/9750000/9747200/9747129/0c19f127.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Isle of Capri Casino Hotel Boonville - A Caesars Rewards Destination [](https://www.expedia.co.uk/Columbia-Hotels-Isle-Of-Capri-Casino-Hotel-Boonville.h9747129.Hotel-Information) Boonville 8.2/10 Very good (948) "Very comfortable room and great location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Richard £84 includes taxes & fees 28 Dec - 29 Dec [](https://www.expedia.co.uk/Columbia-Hotels-Isle-Of-Capri-Casino-Hotel-Boonville.h9747129.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1660000/1658500/1658463/c8809092.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1660000/1658500/1658463/32f9c183.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, iron/ironing board, free cots/infant beds](https://images.trvl-media.com/lodging/2000000/1660000/1658500/1658463/7cee4cdc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1660000/1658500/1658463/985231b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Inn & Suites by Radisson, Columbia, MO [](https://www.expedia.co.uk/Columbia-Hotels-Country-Inn-Suites-By-Radisson.h1658463.Hotel-Information) Columbia 9.0/10 Wonderful (1720) "Was a nice hotel and staff was always around if needed" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kimberly £66 includes taxes & fees 12 Jan - 13 Jan 2026 [](https://www.expedia.co.uk/Columbia-Hotels-Country-Inn-Suites-By-Radisson.h1658463.Hotel-Information) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/890000/882800/882709/4afed9f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/890000/882800/882709/13784ba7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, pool umbrellas](https://images.trvl-media.com/lodging/1000000/890000/882800/882709/31f23fbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking | In-room safe, desk, blackout curtains, iron/ironing board](https://images.trvl-media.com/lodging/1000000/890000/882800/882709/77f38655.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sleep Inn & Suites Lake of the Ozarks [](https://www.expedia.co.uk/Osage-Beach-Hotels-Sleep-Inn-Suites-Lake-Of-The-Ozarks.h882709.Hotel-Information) Camdenton 8.8/10 Excellent (978) "Great room, great breakfast, great price" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kent £78 includes taxes & fees 23 Jan - 24 Jan 2026 [](https://www.expedia.co.uk/Osage-Beach-Hotels-Sleep-Inn-Suites-Lake-Of-The-Ozarks.h882709.Hotel-Information) ![Free daily full breakfast ](https://images.trvl-media.com/lodging/13000000/12550000/12546300/12546284/89f564da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/13000000/12550000/12546300/12546284/e7c009b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/13000000/12550000/12546300/12546284/2c317c73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/13000000/12550000/12546300/12546284/bc9612c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Columbia Inn [](https://www.expedia.co.uk/Columbia-Hotels-Best-Western-Plus-Columbia-Inn.h12546284.Hotel-Information) Columbia 8.8/10 Excellent (1209) "Stayed here several times and was very happy with our stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Reynaldo £60 includes taxes & fees 6 Jan - 7 Jan 2026 [](https://www.expedia.co.uk/Columbia-Hotels-Best-Western-Plus-Columbia-Inn.h12546284.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42200/42129/3e728377.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/50000/42200/42129/56b56482.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/1000000/50000/42200/42129/0ecfd895.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/50000/42200/42129/8e7746ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites Columbia Stadium Boulevard [](https://www.expedia.co.uk/Columbia-Hotels-Drury-Inn-Suites-Columbia-Stadium-Boulevard.h42129.Hotel-Information) Columbia 9.4/10 Exceptional (1006) "Very clean and staff was excellent!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Audrey £75 includes taxes & fees 11 Jan - 12 Jan 2026 [](https://www.expedia.co.uk/Columbia-Hotels-Drury-Inn-Suites-Columbia-Stadium-Boulevard.h42129.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/8000000/7680000/7678000/7677926/8a05cd33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast ](https://images.trvl-media.com/lodging/8000000/7680000/7678000/7677926/4d96f21b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/8000000/7680000/7678000/7677926/w6000h3998x0y0-b5960fdf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/8000000/7680000/7678000/7677926/6f999199.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by IHG [](https://www.expedia.co.uk/Columbia-Hotels-Holiday-Inn-Express-Hotel-Suites-Columbia-Univ-Area-Hwy-63.h7677926.Hotel-Information) Columbia 9.0/10 Wonderful (1003) "Very clean hotel with friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sara £84 includes taxes & fees 5 Jan - 6 Jan 2026 [](https://www.expedia.co.uk/Columbia-Hotels-Holiday-Inn-Express-Hotel-Suites-Columbia-Univ-Area-Hwy-63.h7677926.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1330000/1328700/1328698/7967f13d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, soundproofing, iron/ironing board, cots/infant beds](https://images.trvl-media.com/lodging/2000000/1330000/1328700/1328698/83af4b4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/2000000/1330000/1328700/1328698/56b61525.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1330000/1328700/1328698/d6dce786.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Parkfield Inn [](https://www.expedia.co.uk/Clinton-Hotels-Parkfield-Inn.h1328698.Hotel-Information) Clinton 9.2/10 Wonderful (970) "Great room and great service" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tiffany £81 includes taxes & fees 24 Dec - 25 Dec [](https://www.expedia.co.uk/Clinton-Hotels-Parkfield-Inn.h1328698.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.co.uk/Hotel-Search?startDate=2026-01-06&endDate=2026-01-07®ionId=6058776&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Central Missouri Hotel Reviews ![Baymont by Wyndham Columbia, MO](https://images.trvl-media.com/lodging/1000000/50000/40200/40115/08435bc3_y.jpg) ### Baymont by Wyndham Columbia, MO 10/10 Excellent "Everything was very clean and in working order. A pleasant room." [](https://expedia.co.uk/Columbia-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Columbia.h40115.Hotel-Information) ![Wingate by Wyndham - Columbia](https://images.trvl-media.com/lodging/1000000/990000/986100/986086/a16387a6_y.jpg) ### Wingate by Wyndham - Columbia 10/10 Excellent "I loved my stay. The room was clean and very nice. For a continental breakfast, it was really good." [](https://expedia.co.uk/Columbia-Hotels-Wingate-By-Wyndham-Columbia.h986086.Hotel-Information) ![Stoney Creek Hotel Columbia](https://images.trvl-media.com/lodging/2000000/1060000/1052400/1052330/5398551a_y.jpg) ### Stoney Creek Hotel Columbia 10/10 Excellent "noce atmosphere" [](https://expedia.co.uk/Columbia-Hotels-Stoney-Creek-Hotel-Columbia.h1052330.Hotel-Information) ![Country Inn & Suites by Radisson, Columbia, MO](https://images.trvl-media.com/lodging/2000000/1660000/1658500/1658463/c8809092_y.jpg) ### Country Inn & Suites by Radisson, Columbia, MO 10/10 Excellent "Room was spotless. Staff was friendly. Easy to locate." [](https://expedia.co.uk/Columbia-Hotels-Country-Inn-Suites-By-Radisson.h1658463.Hotel-Information) ![Quality Inn St. Robert - Ft. Leonard Wood](https://images.trvl-media.com/lodging/1000000/220000/218400/218324/63ed2b69_y.jpg) ### Quality Inn St. Robert - Ft. Leonard Wood 10/10 Excellent "The staff was great and the room was clean." [](https://expedia.co.uk/Rolla-Hotels-Quality-Inn-St-Robert-Ft-Leonard-Wood.h218324.Hotel-Information) ![Isle of Capri Casino Hotel Boonville - A Caesars Rewards Destination](https://images.trvl-media.com/lodging/10000000/9750000/9747200/9747129/d7688c2c_y.jpg) ### Isle of Capri Casino Hotel Boonville - A Caesars Rewards Destination 10/10 Excellent "The room was clean and staff was great" [](https://expedia.co.uk/Columbia-Hotels-Isle-Of-Capri-Casino-Hotel-Boonville.h9747129.Hotel-Information) ![Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by IHG](https://images.trvl-media.com/lodging/8000000/7680000/7678000/7677926/8a05cd33_y.jpg) ### Holiday Inn Express Hotel & Suites Columbia Univ Area-Hwy 63 by IHG 10/10 Excellent "Breakfast hostess was so friendly! Room was clean & comfortable." [](https://expedia.co.uk/Columbia-Hotels-Holiday-Inn-Express-Hotel-Suites-Columbia-Univ-Area-Hwy-63.h7677926.Hotel-Information) ![Drury Inn & Suites Columbia Stadium Boulevard](https://images.trvl-media.com/lodging/1000000/50000/42200/42129/3e728377_y.jpg) ### Drury Inn & Suites Columbia Stadium Boulevard 10/10 Excellent "We love Drury inn. Service, rooms, food, everything is good and affordable as well. " [](https://expedia.co.uk/Columbia-Hotels-Drury-Inn-Suites-Columbia-Stadium-Boulevard.h42129.Hotel-Information) ![Lodge Of Four Seasons Golf Resort, Marina & Spa](https://images.trvl-media.com/lodging/1000000/50000/40800/40728/7e36eb59_y.jpg) ### Lodge Of Four Seasons Golf Resort, Marina & Spa 10/10 Excellent "Room was very clean, staff was amazing. The hotel was a little dated" [](https://expedia.co.uk/Osage-Beach-Hotels-Lodge-Of-Four-Seasons-Golf-Resort.h40728.Hotel-Information) ## Frequently asked questions ### How much do business hotels in Central Missouri cost? ### How many business hotels are there in Central Missouri? ### Why book your business hotel in Central Missouri with Expedia? ### How can I find cheap business hotels in Central Missouri? ## Explore a world of travel with Expedia - Accommodation - Flights - Packages - Cars - Holiday Homes - Other - More ways to book - [Apache Flats Hotels ](https://www.expedia.co.uk/Apache-Flats-Hotels.d553248635975850469.Travel-Guide-Hotels) - [Hotels near California Country Club ](https://www.expedia.co.uk/California-Country-Club-Hotels.0-l553248621594455013-0.Travel-Guide-Filter-Hotels) - [California Hotels ](https://www.expedia.co.uk/California-Hotels.d6351831.Travel-Guide-Hotels) - [Adults Only Resorts & in Missouri ](https://www.expedia.co.uk/Destinations-In-Missouri-Adults-Only-Resorts.0-0-d227-tAdultsOnlyResorts.Hotel-Filter-Destinations) - 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