Search Business Hotels in Central Missouri
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check availability on Central Missouri Business Hotels
Our top choices for Central Missouri business-friendly hotels
7.2 out of 10, Good, (350 reviews)
"The accommodations were nice and the staff friendly "
Allison
The price is £46
includes taxes & fees
5 Jul - 6 Jul
8.8 out of 10, Excellent, (1,000 reviews)
"Staff were good - fairly clean room - good nights sleep very basic breakfast but for price still a great deal and good location"
Christopher
The price is £66
includes taxes & fees
2 Aug - 3 Aug
Hotel Bothwell Sedalia Central District, an Ascend Collection Hotel
Hotel Bothwell Sedalia Central District, an Ascend Collection HotelSedalia Downtown Historic District
9.2 out of 10, Wonderful, (623 reviews)
"Friendly staff, clean rooms and delicious food at the hotel restaurant. Always our favorite place to stay when in Sedalia."
Debra
The price is £100
includes taxes & fees
3 Aug - 4 Aug
8.8 out of 10, Excellent, (557 reviews)
"Great place to stay. I would stay here again"
Lori
The price is £74
includes taxes & fees
7 Jul - 8 Jul
9.2 out of 10, Wonderful, (1,001 reviews)
"Great place to stay!!"
Janice
The price is £82
includes taxes & fees
13 Jul - 14 Jul
8.2 out of 10, Very good, (888 reviews)
"Lovely stay, clean room/facilities and staff very friendly."
Kacee
The price is £55
includes taxes & fees
3 Aug - 4 Aug
9.0 out of 10, Wonderful, (1,002 reviews)
"Very nice hotel."
William
The price is £204
includes taxes & fees
1 Aug - 2 Aug
Lodge Of Four Seasons Golf Resort, Marina & Spa
Lodge Of Four Seasons Golf Resort, Marina & SpaLake Ozark
7.4 out of 10, Good, (1,200 reviews)
"Great location & great value!"
Mary
The price is £91
includes taxes & fees
13 Jul - 14 Jul
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Central Missouri Hotel Reviews
Country Inn & Suites by Radisson, Columbia, MO
10/10 Excellent
Frequently asked questions
Explore a world of travel with Expedia
- 5 Star Hotels in Lake Ozark
- Lake house with three decks private dock and swim platform.
- Hotels with Balcony in Central Missouri
- ~A Home Away From Home~Sleeps 8~
- Adults Only Resorts & in Columbia
- Holiday Inn Express Hotel & Suites Columbia Univ Area
- Hottub! private outdoor spaces
- Luxury Modern Downtown Columbia Lofts. 2 Beds
- Private Mother In Law Suite. Cozy One BedRoom With Full Kitchen
- Stoney Creek Hotel Columbia
- Voco The Tiger Hotel Columbia
- Travelodge by Wyndham Jefferson City
- Wingate by Wyndham
- All-Inclusive Hotels in Missouri
- Lakeside Hotels in Missouri
- Missouri Hotels
- Westphalia Inn
- Gay-Friendly Hotels in Hermann
- Gay-Friendly Hotels in Kingdom City
- Charming 3
- Deck House Sleep 12
- [Sale] Lakefront Haven w/ Private Dock
- Luxury Hotels in Lake Ozark
- Private pool
- The Resort at Lake of the Ozarks
- Villa #2 Sleep 10
- Vintage Villa
- Lake Ozark Hotels
- Loose Creek Hotels
- Apartments in Missouri
- Cabin Rentals in Missouri
- Caravan Parks in Missouri
- Chalets in Missouri
- Beautiful waterfront condo with the boat slip! Its five o'clock somewhere...
- Camden on the Lake Resort & Spa
- Eldon Inn
- Hilton Hotels in Osage Beach
- Lodge Of Four Seasons Golf Resort
- Regalia Hotel & Conference Center
- Rocky Mount Hotels
- “Clabe” one of the 5 Tiny Cabins on the Osage River
- Hawthorne Inn
- Wardsville Hotels
- Flights to Central Missouri
- Flights to Columbia
- Flights to Jefferson City
- Flights to Lake Ozark
- Flights to Missouri
- Flights from Columbia Regional
- Flights from Jefferson City Memorial
- Flights from Missouri
- Flights from Loose Creek
- Flights from Mokane
- Flights from California
- Flights from Eldon
- Flights from Jefferson City
- Flights from Columbia
- Flights from Barcelona (BCN) to Columbia (COU)
- Flights from Birmingham (BHM) to Columbia (COU)
- Flights from Nashville (BNA) to Columbia (COU)
- Flights from Nashville (BNA) to Jefferson City (JEF)
- Flights from Boston (BOS) to Columbia (COU)
- Flights from Charlotte (CLT) to Columbia (COU)
- Flights from Dublin (DUB) to Columbia (COU)
- Flights from East Midlands (EMA) to Columbia (COU)
- Flights from Frankfurt (FRA) to Columbia (COU)
- Flights from Houston (IAH) to Columbia (COU)
- Flights from Islamabad (ISB) to Columbia (COU)
- Flights from New York (JFK) to Columbia (COU)
- Flights from London (LCY) to Columbia (COU)
- Flights from London (LHR) to Columbia (COU)
- Flights from London (LHR) to Jefferson City (JEF)
- Flights from Lagos (LOS) to Columbia (COU)
- Flights from Liverpool (LPL) to Columbia (COU)
- Flights from Manchester (MAN) to Columbia (COU)
- Flights from Newcastle (NCL) to Columbia (COU)
- Flights from Norwich (NWI) to Columbia (COU)
- Flights from Chicago (ORD) to Columbia (COU)
- Flights from Southampton (SOU) to Columbia (COU)
- Flights from St. Louis (STL) to Columbia (COU)
- Flights from Tenerife (TFS) to Columbia (COU)
- Flights from Montreal (YUL) to Columbia (COU)
- Flights from Toronto (YYZ) to Columbia (COU)