Title: The 10 Best 5 Star Hotels in Knoxville - 2026 Updated Prices | Expedia.co.uk [Knoxville Travel Guide](https://expedia.co.uk/Knoxville.dx602977)[Hotels in Knoxville](https://expedia.co.uk/Knoxville-Hotels.d602977.Travel-Guide-Hotels)[Holiday Rentals in Knoxville](https://expedia.co.uk/Knoxville-Holiday-Rentals.d602977.Travel-Guide-HolidayRentals)[Flights to Knoxville](https://expedia.co.uk/Cheap-Flights-To-Knoxville.d602977.Travel-Guide-Flights)[Things to do in Knoxville](https://expedia.co.uk/Things-To-Do-In-Knoxville.d602977.Travel-Guide-Activities)[Knoxville Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Knoxville.d602977.Car-Hire-Guide)[Knoxville Holidays](https://expedia.co.uk/Knoxville.d602977.Holidays-City-Breaks) ![Skyline of downtown Knoxville, Tennessee, USA](https://images.trvl-media.com/place/602977/e5dfacc8-29fe-4ae7-93f0-6aa1cd8e604b.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/602977/e5dfacc8-29fe-4ae7-93f0-6aa1cd8e604b.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Knoxville 5 Star Hotels Tonight [2 Mar - 3 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=602977&startDate=2026-03-02&endDate=2026-03-03&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [3 Mar - 4 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=602977&startDate=2026-03-03&endDate=2026-03-04&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [6 Mar - 8 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=602977&startDate=2026-03-06&endDate=2026-03-08&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [13 Mar - 15 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=602977&startDate=2026-03-13&endDate=2026-03-15&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Knoxville-Hotels.s50-0-d602977.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Knoxville-Hotels.s50-0-d602977.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Knoxville. ![THE TENNESSEAN Hotel](https://images.trvl-media.com/lodging/17000000/16740000/16736300/16736258/fe36e988_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### THE TENNESSEAN Hotel 531 Henley Street Knoxville TN £155 1 Apr - 2 Apr includes taxes & fees 9.6/10 Exceptional! (1,003 reviews) [](https://expedia.co.uk/Knoxville-Hotels-The-Tennessean-Personal-Luxury-Hotel.h16736258.Hotel-Information) ![Graduate by Hilton Knoxville](https://images.trvl-media.com/lodging/37000000/36050000/36050000/36049999/d3013894_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Graduate by Hilton Knoxville 1706 Cumberland Ave Knoxville TN £122 8 Mar - 9 Mar includes taxes & fees 9/10 Wonderful! (1,001 reviews) [](https://expedia.co.uk/Knoxville-Hotels-The-Volunteer-Hotel.h36049999.Hotel-Information) ![Marriott Knoxville Downtown](https://images.trvl-media.com/lodging/1000000/10000/2700/2646/w4000h2664x0y3-aec2e5f8_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Marriott Knoxville Downtown 525 Henley St Knoxville TN £105 8 Mar - 9 Mar includes taxes & fees 9/10 Wonderful! (671 reviews) [](https://expedia.co.uk/Knoxville-Hotels-Marriott-Knoxville-Downtown.h2646.Hotel-Information) Still don't see what you're looking for? [See all properties in Knoxville.](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=03%2F03%2F2026&endDate=04%2F03%2F2026®ionId=602977&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=03%2F03%2F2026&endDate=04%2F03%2F2026®ionId=602977&star=50&star=50&amenities=POOL)[Spa](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=03%2F03%2F2026&endDate=04%2F03%2F2026®ionId=602977&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=03%2F03%2F2026&endDate=04%2F03%2F2026®ionId=602977&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=03%2F03%2F2026&endDate=04%2F03%2F2026®ionId=602977&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=03%2F03%2F2026&endDate=04%2F03%2F2026®ionId=602977&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Knoxville and related destinations - Knoxville - New Haven - Athens - Greenville - Spartanburg - Birmingham Nestled along the Tennessee River, this vibrant city blends Appalachian charm with a thriving arts scene at the historic Market Square. Outdoor enthusiasts can hike nearby Smoky Mountain trails, then return for live music and Southern comfort food at locally-owned city centre restaurants. [See all hotels in Knoxville](https://www.expedia.co.uk/Hotel-Search?startDate=2026-03-16&endDate=2026-03-17&adults=2®ionId=602977) ![Skyline of downtown Knoxville, Tennessee, USA](https://images.trvl-media.com/place/602977/e5dfacc8-29fe-4ae7-93f0-6aa1cd8e604b.jpg?impolicy=fcrop&w=900&h=562&p=1&q=high) ## Top Knoxville Hotel Reviews ## Find out more about Knoxville ## Frequently asked questions ### How much does it cost to stay in a 5-star hotel in Knoxville? > - Search for the lowest price per night from £105 ### What makes a hotel 5 stars in Knoxville? ### Are there any 5-star all-inclusive resorts in Knoxville? ## Explore a world of travel with Expedia - More ways to book - [Book 5 Star Hotels in Knoxville on Expedia.com ](https://www.expedia.com/5Star-Knoxville-Hotels.s50-0-d602977.Travel-Guide-Filter-Hotels)