A marina with various boats docked, a wooden pier, and houses in the background.

Compare and book 5 Star hotels in Hyannis, Massachusetts

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Save instantly and earn perks with One Key
    Learn about One Key

  • Be picky

    Search almost a million properties worldwide

Check availability on Hyannis 5 Star Hotels

Our top choices for Hyannis 5-star hotels

Exterior

Chatham Bars Inn

Chatham Bars Inn
5.0 star property
Chatham
9.2 out of 10, Wonderful, (845 reviews)
"Nice location with short walk into Chatham. Restaurants were good with great views. Overall we had a very nice stay."
United States
Marilyn
The price is £883
includes taxes & fees
26 Jul - 27 Jul
Chatham Bars Inn
Round Cove Suite | Frette Italian sheets, premium bedding, down duvets, minibar

Wequassett Resort and Golf Club

Wequassett Resort and Golf Club
5.0 star property
Harwich
9.4 out of 10, Exceptional, (260 reviews)
"This place is the best prettiest most wonderful place on Cape Cod! The gardens are spectacular! The pool beautiful and all restaurants exceptional!"
United States
Wendy
The price is £1,018
includes taxes & fees
12 Jul - 13 Jul
Wequassett Resort and Golf Club
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Hyannis.
Margaritaville Resort Cape Cod

Margaritaville Resort Cape Cod

1225 Iyannough Rd Hyannis MA
The price is £262 per night from 16 Jul to 17 Jul
£262
16 Jul - 17 Jul
includes taxes & fees
8.6/10 Excellent! (622 reviews)
Still don't see what you're looking for?
See all properties in Hyannis.
You can also use these popular filters to refine your search.
PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Hyannis

Stroll the bustling harbour and hop aboard a ferry to Martha's Vineyard or Nantucket for a day trip. Visit the John F. Kennedy Hyannis Museum to learn about the president's connection to Cape Cod's summer playground.

See all hotels in Hyannis
A marina with various boats docked, a wooden pier, and houses in the background.

Top Hyannis Hotel Reviews

Find out more about Hyannis

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Hyannis?
You'll find many different pricing options for 5-star hotels in Hyannis on Expedia. How much you'll pay will depend on when you travel, trip length and other factors. Compare available properties for your desired dates and make use of our pricing and other filters to lock in the perfect luxury stay.

  • Search for the lowest price per night from £229

What makes a hotel 5 stars in Hyannis?
Exceptional guest service is integral to every 5-star hotel in Hyannis. From the moment you arrive, staff cater to your every need, whether recommending activities or providing in-room beauty treatments. In addition, hotels must feature top-rate amenities to meet the standard for a 5-star rating. These can include luxury toiletries, on-site spa facilities, swimming pools, fine dining kitchens and knowledgeable concierge.
Are there any 5-star all-inclusive resorts in Hyannis?
Use our filter tool to find a high-end getaway in Hyannis where most of what you need is included. After your initial search, refine your results for properties that have a rating of 5 stars and are described as "All inclusive." The most important thing on the agenda at these stays? Pure enjoyment and indulgence.

Explore a world of travel with Expedia