Title: The 10 Best 5 Star Hotels in Gulf of Mexico - 2026 Updated Prices | Expedia.co.uk [Gulf of Mexico Travel Guide](https://expedia.co.uk/Gulf-Of-Mexico.dx553248635989303400)[Hotels in Gulf of Mexico](https://expedia.co.uk/Gulf-Of-Mexico-Hotels.d553248635989303400.Travel-Guide-Hotels)[Holiday Rentals in Gulf of Mexico](https://expedia.co.uk/Gulf-Of-Mexico-Holiday-Rentals.d553248635989303400.Travel-Guide-HolidayRentals)[Flights to Gulf of Mexico](https://expedia.co.uk/Cheap-Flights-To-Gulf-Of-Mexico.d553248635989303400.Travel-Guide-Flights)[Things to do in Gulf of Mexico](https://expedia.co.uk/Things-To-Do-In-Gulf-Of-Mexico.d553248635989303400.Travel-Guide-Activities)[Gulf of Mexico Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Gulf-Of-Mexico.d553248635989303400.Car-Hire-Guide)[Gulf of Mexico Holidays](https://expedia.co.uk/Gulf-Of-Mexico.d553248635989303400.Holidays-City-Breaks) ![The crystal clear waters of the Gulf of Mexico surround Civil War Historic Fort Jefferson in the Dry Tortugas](https://images.trvl-media.com/place/553248635989303400/2363522f-2e51-4e19-90bf-e9db449072dd.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/553248635989303400/2363522f-2e51-4e19-90bf-e9db449072dd.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Gulf of Mexico 5 Star Hotels Tonight [2 Mar - 3 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=553248635989303400&startDate=2026-03-02&endDate=2026-03-03&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [3 Mar - 4 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=553248635989303400&startDate=2026-03-03&endDate=2026-03-04&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [6 Mar - 8 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=553248635989303400&startDate=2026-03-06&endDate=2026-03-08&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [13 Mar - 15 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=553248635989303400&startDate=2026-03-13&endDate=2026-03-15&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Gulf of Mexico 5-star hotels ![Lobby](https://images.trvl-media.com/lodging/3000000/2670000/2661400/2661313/bcb645d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2670000/2661400/2661313/eeb74411.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/3000000/2670000/2661400/2661313/b3dc555a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2670000/2661400/2661313/888a5eb2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Roosevelt New Orleans, A Waldorf Astoria Hotel [](https://www.expedia.co.uk/New-Orleans-Hotels-The-Roosevelt-New-Orleans.h2661313.Hotel-Information) New Orleans Central Business District 9.2/10 Wonderful (1,004 reviews) "great location and hotel!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tamara £212 includes taxes & fees 15 Mar - 16 Mar [](https://www.expedia.co.uk/New-Orleans-Hotels-The-Roosevelt-New-Orleans.h2661313.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/1000000/30000/26000/25999/e8f2bef5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/30000/26000/25999/3efc4a26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/26000/25999/f4f781de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 6:00 AM to 10:00 PM, pool cabanas (surcharge)](https://images.trvl-media.com/lodging/1000000/30000/26000/25999/116c3686.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Windsor Court [](https://www.expedia.co.uk/New-Orleans-Hotels-The-Windsor-Court.h25999.Hotel-Information) New Orleans Central Business District 9.8/10 Exceptional (1,003 reviews) "Staff very courteous. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Don £324 includes taxes & fees 8 Mar - 9 Mar [](https://www.expedia.co.uk/New-Orleans-Hotels-The-Windsor-Court.h25999.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/84000000/83990000/83980300/83980287/7b52caf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/84000000/83990000/83980300/83980287/3fbaba62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/84000000/83990000/83980300/83980287/6ac45685.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/84000000/83990000/83980300/83980287/8d2fa88d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Tampa EDITION [](https://www.expedia.co.uk/Tampa-Hotels-The-Tampa-EDITION.h83980287.Hotel-Information) Downtown Tampa 9.4/10 Exceptional (347 reviews) "Clean room, staff was very courteous " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Grant £393 includes taxes & fees 2 Apr - 3 Apr [](https://www.expedia.co.uk/Tampa-Hotels-The-Tampa-EDITION.h83980287.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/16000000/15200000/15192500/15192425/4c7b7bb2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/16000000/15200000/15192500/15192425/e4bf279c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/16000000/15200000/15192500/15192425/390a42b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/16000000/15200000/15192500/15192425/939ecd5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Henderson Beach Resort & Spa [](https://www.expedia.co.uk/Destin-Hotels-The-Henderson.h15192425.Hotel-Information) Crystal Beach 9.2/10 Wonderful (1,001 reviews) "Beautiful resort and close to shopping and great restaurants! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Daniel £290 includes taxes & fees 22 Mar - 23 Mar [](https://www.expedia.co.uk/Destin-Hotels-The-Henderson.h15192425.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/68000000/67120000/67114900/67114834/85074655.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/68000000/67120000/67114900/67114834/df24b91c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/68000000/67120000/67114900/67114834/b9b0f63e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/68000000/67120000/67114900/67114834/2f0a463a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Four Seasons Hotel New Orleans [](https://www.expedia.co.uk/New-Orleans-Hotels-Four-Seasons-Hotel-New-Orleans.h67114834.Hotel-Information) New Orleans Central Business District 9.6/10 Exceptional (627 reviews) "Clean room and very friendly staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jonathan £402 includes taxes & fees 9 Mar - 10 Mar [](https://www.expedia.co.uk/New-Orleans-Hotels-Four-Seasons-Hotel-New-Orleans.h67114834.Hotel-Information) ![On the beach, sun-loungers, beach umbrellas, beach towels](https://images.trvl-media.com/lodging/25000000/24110000/24101800/24101706/f6566b0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/25000000/24110000/24101800/24101706/04484d29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast and dinner served](https://images.trvl-media.com/lodging/25000000/24110000/24101800/24101706/02a3a50c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast and dinner served](https://images.trvl-media.com/lodging/25000000/24110000/24101800/24101706/9f64224f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Isla Bella Beach Resort & Spa [](https://www.expedia.co.uk/Marathon-Hotels-Isla-Bella-Beach-Resort-Spa.h24101706.Hotel-Information) Marathon 9.2/10 Wonderful (1,097 reviews) "great resort " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Niki £518 includes taxes & fees 22 Mar - 23 Mar [](https://www.expedia.co.uk/Marathon-Hotels-Isla-Bella-Beach-Resort-Spa.h24101706.Hotel-Information) ![3BR Group Haven + Private Patio Walk to French Qtr | The Mayfair | Living area | 65-inch Smart TV with cable channels, Netflix, Hulu](https://images.trvl-media.com/lodging/116000000/115540000/115539900/115539817/d45ceeae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4BR 2-Story Historic Space Steps to French Quarter | The Mayfair | Bathroom | Shower, eco-friendly toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/116000000/115540000/115539900/115539817/e6b624a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3BR Lavish Penthouse + Canal St Private Patio | The Mayfair | Living area | 65-inch Smart TV with cable channels, Netflix, Hulu](https://images.trvl-media.com/lodging/116000000/115540000/115539900/115539817/ad3bb0c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2BR Elegant French Quarter Escape | The Mayfair | Premium bedding, individually decorated, individually furnished](https://images.trvl-media.com/lodging/116000000/115540000/115539900/115539817/eb7d2cb7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Mayfair [](https://www.expedia.co.uk/New-Orleans-Hotels-The-Mayfair.h115539817.Hotel-Information) French Quarter 9.0/10 Wonderful (2 reviews) "The best hotel I stayed in a longtime. Very clean and staff is so pleasant self check in so convenient. Perfect spot if you are visiting New Orleans/ bourbon street " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shanika £404 includes taxes & fees 10 Mar - 11 Mar [](https://www.expedia.co.uk/New-Orleans-Hotels-The-Mayfair.h115539817.Hotel-Information) ![Jade House at The Gemma | 6 bedrooms, premium bedding, memory-foam beds, individually decorated](https://images.trvl-media.com/lodging/105000000/104290000/104287800/104287738/c01a9a15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pearl House at The Gemma | Living area | 55-inch Smart TV with digital channels, Netflix, Hulu](https://images.trvl-media.com/lodging/105000000/104290000/104287800/104287738/f4246993.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Jade House at The Gemma | Terrace/patio](https://images.trvl-media.com/lodging/105000000/104290000/104287800/104287738/f182b7cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Akoya House at The Gemma | Private kitchen | Full-sized fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/105000000/104290000/104287800/104287738/eecd8b9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Gemma by Brightwild [](https://www.expedia.co.uk/St-Petersburg-Clearwater-Hotels-The-Gemma-By-Brightwild.h104287738.Hotel-Information) Clearwater Beach 10/10 Exceptional (2 reviews) "Amazing property" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rusty £1,062 includes taxes & fees 3 Mar - 4 Mar [](https://www.expedia.co.uk/St-Petersburg-Clearwater-Hotels-The-Gemma-By-Brightwild.h104287738.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Gulf-Of-Mexico-Hotels.s50-0-d553248635989303400.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Gulf-Of-Mexico-Hotels.s50-0-d553248635989303400.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Gulf of Mexico. ![The Westin Tampa Bay](https://images.trvl-media.com/lodging/1000000/10000/1600/1557/5e6ee943_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### The Westin Tampa Bay 7627 W Courtney Campbell Cswy Tampa FL £157 29 Mar - 30 Mar includes taxes & fees 8.4/10 Very Good! (1,142 reviews) [](https://expedia.co.uk/Tampa-Hotels-Westin-Tampa-Bay-Hotel.h1557.Hotel-Information) ![RumFish Beach at TradeWinds](https://images.trvl-media.com/lodging/1000000/10000/8600/8544/37eb40ec_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### RumFish Beach at TradeWinds 6000 Gulf Blvd St. Pete Beach FL £295 4 Mar - 5 Mar includes taxes & fees 8.2/10 Very Good! (1,654 reviews) [](https://expedia.co.uk/St-Petersburg-Clearwater-Hotels-RumFish-Beach-Resort-By-TradeWinds.h8544.Hotel-Information) ![Island Grand at TradeWinds](https://images.trvl-media.com/lodging/1000000/10000/2000/1914/6ca26be4_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Island Grand at TradeWinds 5500 Gulf Blvd St. Pete Beach FL £302 3 Mar - 4 Mar includes taxes & fees 7.6/10 Good! (1,023 reviews) [](https://expedia.co.uk/St-Petersburg-Clearwater-Hotels-TradeWinds-Island-Grand.h1914.Hotel-Information) Still don't see what you're looking for? [See all properties in Gulf of Mexico.](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=03%2F03%2F2026&endDate=04%2F03%2F2026®ionId=553248635989303400&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=03%2F03%2F2026&endDate=04%2F03%2F2026®ionId=553248635989303400&star=50&star=50&amenities=POOL)[Spa](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=03%2F03%2F2026&endDate=04%2F03%2F2026®ionId=553248635989303400&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=03%2F03%2F2026&endDate=04%2F03%2F2026®ionId=553248635989303400&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=03%2F03%2F2026&endDate=04%2F03%2F2026®ionId=553248635989303400&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=03%2F03%2F2026&endDate=04%2F03%2F2026®ionId=553248635989303400&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about Gulf of Mexico Plan your trip to Gulf of Mexico and take advantage of the sights and activities in the area. [See all hotels in Gulf of Mexico](https://www.expedia.co.uk/Hotel-Search?startDate=2026-03-16&endDate=2026-03-17&adults=2®ionId=553248635989303400) ![The crystal clear waters of the Gulf of Mexico surround Civil War Historic Fort Jefferson in the Dry Tortugas](https://images.trvl-media.com/place/553248635989303400/2363522f-2e51-4e19-90bf-e9db449072dd.jpg?impolicy=fcrop&w=900&h=600&p=1&q=high) ## Top Gulf of Mexico Hotel Reviews ## Find out more about Gulf of Mexico