Title: The 10 Best 5 Star Hotels in Gulf of Mexico - 2025 Updated Prices | Expedia.co.uk [Gulf of Mexico Travel Guide](https://expedia.co.uk/Gulf-Of-Mexico.dx553248635989303400)[Hotels in Gulf of Mexico](https://expedia.co.uk/Gulf-Of-Mexico-Hotels.d553248635989303400.Travel-Guide-Hotels)[Holiday Rentals in Gulf of Mexico](https://expedia.co.uk/Gulf-Of-Mexico-Holiday-Rentals.d553248635989303400.Travel-Guide-HolidayRentals)[Flights to Gulf of Mexico](https://expedia.co.uk/Cheap-Flights-To-Gulf-Of-Mexico.d553248635989303400.Travel-Guide-Flights)[Things to do in Gulf of Mexico](https://expedia.co.uk/Things-To-Do-In-Gulf-Of-Mexico.d553248635989303400.Travel-Guide-Activities)[Gulf of Mexico Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Gulf-Of-Mexico.d553248635989303400.Car-Hire-Guide)[Gulf of Mexico Holidays](https://expedia.co.uk/Gulf-Of-Mexico.d553248635989303400.Holidays-City-Breaks) ![The crystal clear waters of the Gulf of Mexico surround Civil War Historic Fort Jefferson in the Dry Tortugas](https://images.trvl-media.com/place/553248635989303400/2363522f-2e51-4e19-90bf-e9db449072dd.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Compare and book 5 Star hotels in Gulf of Mexico, - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Gulf of Mexico 5 Star Hotels Tonight [30 Nov - 1 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248635989303400&startDate=2025-11-30&endDate=2025-12-01&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [1 Dec - 2 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248635989303400&startDate=2025-12-01&endDate=2025-12-02&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [5 Dec - 7 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248635989303400&startDate=2025-12-05&endDate=2025-12-07&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [12 Dec - 14 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=553248635989303400&startDate=2025-12-12&endDate=2025-12-14&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Gulf of Mexico 5 Star Hotels ![Reception](https://images.trvl-media.com/lodging/3000000/2670000/2661400/2661313/6b04cc50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor wedding](https://images.trvl-media.com/lodging/3000000/2670000/2661400/2661313/b62f3aae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 9 AM to 7 PM, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/3000000/2670000/2661400/2661313/230a8730.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2670000/2661400/2661313/49b178b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Roosevelt New Orleans, A Waldorf Astoria Hotel New Orleans Central Business District 9.2/10 Wonderful (1016) "We found our stay here to be very enjoyable." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lesley £158 includes taxes & fees 7 Dec - 8 Dec [](https://www.expedia.co.uk/New-Orleans-Hotels-The-Roosevelt-New-Orleans.h2661313.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/1000000/30000/26000/25999/e8f2bef5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; American cuisine, garden views ](https://images.trvl-media.com/lodging/1000000/30000/26000/25999/9c8cbe9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/30000/26000/25999/3efc4a26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fountain](https://images.trvl-media.com/lodging/1000000/30000/26000/25999/2cecbd9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Windsor Court New Orleans Central Business District 9.8/10 Exceptional (1007) "Wonderful stay with my family. Great staff and very clean." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jonathan £346 includes taxes & fees 24 Dec - 25 Dec [](https://www.expedia.co.uk/New-Orleans-Hotels-The-Windsor-Court.h25999.Hotel-Information) ![Outdoor pool, pool cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/84000000/83990000/83980300/83980287/cbddc2cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/84000000/83990000/83980300/83980287/2da1f24c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/84000000/83990000/83980300/83980287/7b52caf6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Garden](https://images.trvl-media.com/lodging/84000000/83990000/83980300/83980287/8d2fa88d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Tampa EDITION Downtown Tampa 9.2/10 Wonderful (312) "Loved this hotel!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karem £284 includes taxes & fees 22 Dec - 23 Dec [](https://www.expedia.co.uk/Tampa-Hotels-The-Tampa-EDITION.h83980287.Hotel-Information) ![Private beach, sun-loungers, beach umbrellas, beach towels](https://images.trvl-media.com/lodging/1000000/10000/5800/5780/617c0723.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/5800/5780/9b929f51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/1000000/10000/5800/5780/981feca1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Balcony](https://images.trvl-media.com/lodging/1000000/10000/5800/5780/79d31a44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cheeca Lodge & Spa Matecumbe 9.2/10 Wonderful (1278) "Everything about our stay was amazing and exceeded our expectations in every way!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mary Frances £214 includes taxes & fees 19 Dec - 20 Dec [](https://www.expedia.co.uk/Islamorada-Hotels-Cheeca-Lodge-Spa.h5780.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/68000000/67120000/67114900/67114834/e4fbb3bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/68000000/67120000/67114900/67114834/bfc41fc0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/68000000/67120000/67114900/67114834/85074655.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/68000000/67120000/67114900/67114834/df24b91c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Four Seasons Hotel New Orleans New Orleans Central Business District 9.6/10 Exceptional (590) "Beautiful hotel, amazing service, huge room " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeffrey £354 includes taxes & fees 22 Dec - 23 Dec [](https://www.expedia.co.uk/New-Orleans-Hotels-Four-Seasons-Hotel-New-Orleans.h67114834.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/25000000/24110000/24101800/24101706/f4f56036.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/25000000/24110000/24101800/24101706/e1765627.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast and dinner served](https://images.trvl-media.com/lodging/25000000/24110000/24101800/24101706/02a3a50c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast and dinner served](https://images.trvl-media.com/lodging/25000000/24110000/24101800/24101706/9f64224f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Isla Bella Beach Resort & Spa Marathon 9.2/10 Wonderful (1064) "Rooms and property were very clean . " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jessica £252 includes taxes & fees 1 Dec - 2 Dec [](https://www.expedia.co.uk/Marathon-Hotels-Isla-Bella-Beach-Resort-Spa.h24101706.Hotel-Information) ![French cuisine](https://images.trvl-media.com/lodging/31000000/30470000/30463700/30463621/569e8fd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/31000000/30470000/30463700/30463621/377413fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/31000000/30470000/30463700/30463621/601de56b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/31000000/30470000/30463700/30463621/8ab6a126.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Maison Métier, in the Unbound Collection by Hyatt New Orleans Central Business District 9.8/10 Exceptional (256) "Spotless rooms, incredible staff! Couldn’t say enough good things! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ashley Marie £285 includes taxes & fees 15 Dec - 16 Dec [](https://www.expedia.co.uk/New-Orleans-Hotels-Maison-Metier.h30463621.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/16000000/15200000/15192500/15192425/939ecd5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/16000000/15200000/15192500/15192425/3bac2209.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sun deck](https://images.trvl-media.com/lodging/16000000/15200000/15192500/15192425/0b7f4f27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/16000000/15200000/15192500/15192425/4c7b7bb2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Henderson Beach Resort & Spa Crystal Beach 9.2/10 Wonderful (1002) "Beautiful hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) stefanie £221 includes taxes & fees 1 Dec - 2 Dec [](https://www.expedia.co.uk/Destin-Hotels-The-Henderson.h15192425.Hotel-Information) ![Private beach nearby, white sand, free beach shuttle, beach cabanas](https://images.trvl-media.com/lodging/1000000/810000/806200/806101/90558b2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/810000/806200/806101/36b8ca60.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![5 restaurants, breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/1000000/810000/806200/806101/3e724949.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Private beach nearby, white sand, free beach shuttle, beach cabanas](https://images.trvl-media.com/lodging/1000000/810000/806200/806101/8d484916.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Ritz-Carlton, Sarasota Central Sarasota 9.2/10 Wonderful (1004) "Great service, comfortable beds" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Richard £518 includes taxes & fees 14 Dec - 15 Dec [](https://www.expedia.co.uk/Sarasota-Hotels-The-Ritz-Carlton.h806101.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/460000/454900/454890/w4000h2663x0y0-92d7c7f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/460000/454900/454890/be504478.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/460000/454900/454890/df789d44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/460000/454900/454890/2f401f6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Ritz-Carlton, New Orleans French Quarter 9.2/10 Wonderful (1010) "Beautiful room. Fantastic staff Loved the live music in the lounge" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David £264 includes taxes & fees 23 Dec - 24 Dec [](https://www.expedia.co.uk/New-Orleans-Hotels-The-Ritz-Carlton.h454890.Hotel-Information) ![The Adaline #6 - 2nd Floor Suite | Dining room](https://images.trvl-media.com/lodging/97000000/96050000/96044100/96044015/2cb71c62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/97000000/96050000/96044100/96044015/9e84d960.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down duvets, Tempur-Pedic beds, individually decorated](https://images.trvl-media.com/lodging/97000000/96050000/96044100/96044015/17a5bd03.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![The Adaline #7 - Second Floor Suite | View from room](https://images.trvl-media.com/lodging/97000000/96050000/96044100/96044015/73c042ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Adaline Hyde Park 9.6/10 Exceptional (55) "4th time staying here. Amazing stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dawn £240 includes taxes & fees 8 Dec - 9 Dec [](https://www.expedia.co.uk/Tampa-Hotels-The-Adaline.h96044015.Hotel-Information) ![Jade House at The Gemma | Living area | 55-inch Smart TV with digital channels, Netflix, Hulu](https://images.trvl-media.com/lodging/105000000/104290000/104287800/104287738/79e8e064.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Onyx House at The Gemma | Private spa tub](https://images.trvl-media.com/lodging/105000000/104290000/104287800/104287738/d9b050db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pearl House at The Gemma | Living area | 55-inch Smart TV with digital channels, Netflix, Hulu](https://images.trvl-media.com/lodging/105000000/104290000/104287800/104287738/f4246993.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Jade House at The Gemma | 6 bedrooms, premium bedding, memory-foam beds, individually decorated](https://images.trvl-media.com/lodging/105000000/104290000/104287800/104287738/bacd0ac5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Gemma by Brightwild Clearwater Beach 10/10 Exceptional (2) "Amazing property" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rusty £1,200 includes taxes & fees 1 Dec - 2 Dec [](https://www.expedia.co.uk/St-Petersburg-Clearwater-Hotels-The-Gemma-By-Brightwild.h104287738.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Gulf-Of-Mexico-Hotels.s50-0-d553248635989303400.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Gulf-Of-Mexico-Hotels.s50-0-d553248635989303400.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Gulf of Mexico. ![Moody Gardens Hotel, Spa and Convention Center](https://images.trvl-media.com/lodging/1000000/160000/157300/157238/2dae7fa0_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Moody Gardens Hotel, Spa and Convention Center 7 Hope Blvd Galveston TX £81 8 Dec - 9 Dec includes taxes & fees 8.8/10 Excellent! (1,950 reviews) [](https://expedia.co.uk/Galveston-Hotels-Moody-Gardens-Hotel.h157238.Hotel-Information) ![Hard Rock Hotel & Casino Biloxi](https://images.trvl-media.com/lodging/2000000/1740000/1731600/1731566/7e1bb110_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hard Rock Hotel & Casino Biloxi 777 Beach Blvd. Biloxi MS £76 7 Dec - 8 Dec includes taxes & fees 8.2/10 Very Good! (3,602 reviews) [](https://expedia.co.uk/Biloxi-Hotels-Hard-Rock-Hotel-Casino-Biloxi.h1731566.Hotel-Information) ![Hyatt Regency New Orleans](https://images.trvl-media.com/lodging/1000000/20000/13400/13394/b1f1bb61_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hyatt Regency New Orleans 601 Loyola Avenue New Orleans LA £139 26 Dec - 27 Dec includes taxes & fees 9/10 Wonderful! (1,457 reviews) [](https://expedia.co.uk/New-Orleans-Hotels-Hyatt-Regency-New-Orleans.h13394.Hotel-Information) Still don't see what you're looking for? [See all properties in Gulf of Mexico.](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=01%2F12%2F2025&endDate=02%2F12%2F2025®ionId=553248635989303400&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=01%2F12%2F2025&endDate=02%2F12%2F2025®ionId=553248635989303400&star=50&star=50&amenities=POOL)[Spa](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=01%2F12%2F2025&endDate=02%2F12%2F2025®ionId=553248635989303400&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=01%2F12%2F2025&endDate=02%2F12%2F2025®ionId=553248635989303400&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=01%2F12%2F2025&endDate=02%2F12%2F2025®ionId=553248635989303400&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=01%2F12%2F2025&endDate=02%2F12%2F2025®ionId=553248635989303400&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about Gulf of Mexico Plan your trip to Gulf of Mexico and take advantage of the sights and activities in the area. [See all hotels in Gulf of Mexico](https://www.expedia.co.uk/Hotel-Search?startDate=2025-12-14&endDate=2025-12-15&adults=2®ionId=553248635989303400) ![The crystal clear waters of the Gulf of Mexico surround Civil War Historic Fort Jefferson in the Dry Tortugas](https://images.trvl-media.com/place/553248635989303400/2363522f-2e51-4e19-90bf-e9db449072dd.jpg?impolicy=fcrop&w=900&h=600&p=1&q=high) ## Top Gulf of Mexico Hotel Reviews ## Find out more about Gulf of Mexico