Compare and book 5 Star hotels in Florida Keys, United States of America

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Check availability on Florida Keys 5 Star Hotels

Tonight
21 Jul - 22 Jul
Tomorrow
22 Jul - 23 Jul
This weekend
25 Jul - 27 Jul
Next weekend
1 Aug - 3 Aug

Top Florida Keys 5 Star Hotels

Cheeca Lodge & Spa
Private beach, sun-loungers, beach umbrellas, beach towels

Cheeca Lodge & Spa

5.0 star property
9.0 out of 10, Wonderful, (1139)
"We absolutely loved our stay at cheeca, will not be our last!"
The price is £261
includes taxes & fees
19 Aug - 20 Aug
Cheeca Lodge & Spa
Isla Bella Beach Resort & Spa
Property grounds

Isla Bella Beach Resort & Spa

5.0 star property
9.2 out of 10, Wonderful, (1006)
"Had a great stay"
The price is £287
includes taxes & fees
20 Aug - 21 Aug
Isla Bella Beach Resort & Spa
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Florida Keys.
Hawks Cay Resort

Hawks Cay Resort

61 Hawks Cay Blvd, Marathon, FL
The price is £359 per night from 28 Jul to 29 Jul
£359
28 Jul - 29 Jul
includes taxes & fees
8/10 Very Good! (1,006 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Florida Keys

Discover the seaside area of Florida Keys—live music, beaches and top sights like Duval Street.

See all hotels in Florida Keys
Higgs Beach showing tropical scenes and a beach as well as a large group of people

Top Florida Keys Hotel Reviews

Cheeca Lodge & Spa

Cheeca Lodge & Spa

10/10 Excellent
"Amazing "
Oksana 2-night trip
Posted 4 days ago
Cheeca Lodge & Spa
Isla Bella Beach Resort & Spa

Isla Bella Beach Resort & Spa

10/10 Excellent
"Love, love love this place!!!!!!! It’s beautiful, laid back and fun. We will definitely be back. "
Guy 6-night trip
Posted 7 days ago
Isla Bella Beach Resort & Spa

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Florida Keys?
How much you pay for a 5-star hotel in Florida Keys depends on factors like when you plan to go and the length of your stay. A top tip for bagging an awesome deal? Use our pricing filters to check out the available accommodation for your chosen dates.

  • Search for the lowest price per night from £221

What makes a hotel 5 stars in Florida Keys?
Impeccable guest service is integral to every 5-star hotel in Florida Keys. From the second you arrive, staff ensure your every need is met, whether recommending activities or providing a turn-down service. What's more, hotels must feature superior conveniences to meet the standard for a 5-star rating. These can include luxury bathrooms, on-site spa facilities, swimming pools, gastronomic restaurants and knowledgeable concierge.
Are there any 5-star all-inclusive resorts in Florida Keys?
Find a luxurious retreat that includes your room, meals, drinks and entertainment in Florida Keys with the help of our filters. Search for hotels with a 5-star rating and select the "All inclusive" filter. Have a look at what's included in the price. This way, you can take full advantage of all the perks on offer from the moment you arrive.