Title: The 10 Best 4 Star Hotels in Panama Canal Zone - 2026 Updated Prices | Expedia.co.uk [Panama Canal Zone Travel Guide](https://expedia.co.uk/Panama-Canal-Zone.dx6222968)[Hotels in Panama Canal Zone](https://expedia.co.uk/Panama-Canal-Zone-Hotels.d6222968.Travel-Guide-Hotels)[Holiday Rentals in Panama Canal Zone](https://expedia.co.uk/Panama-Canal-Zone-Holiday-Rentals.d6222968.Travel-Guide-HolidayRentals)[Flights to Panama Canal Zone](https://expedia.co.uk/Cheap-Flights-To-Panama-Canal-Zone.d6222968.Travel-Guide-Flights)[Panama Canal Zone Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Panama-Canal-Zone.d6222968.Car-Hire-Guide)[Panama Canal Zone Holidays](https://expedia.co.uk/Panama-Canal-Zone.d6222968.Holidays-City-Breaks) ![0_BU000512](https://images.trvl-media.com/place/6222968/089e46e9-cc78-4d6b-b43a-af08a95dd797.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Compare and book 4 Star hotels in Panama Canal Zone, Panama - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Panama Canal Zone 4 Star Hotels Tonight [24 Dec - 25 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6222968&startDate=2025-12-24&endDate=2025-12-25&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [25 Dec - 26 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6222968&startDate=2025-12-25&endDate=2025-12-26&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [26 Dec - 28 Dec](https://www.expedia.co.uk/Hotel-Search?regionId=6222968&startDate=2025-12-26&endDate=2025-12-28&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [2 Jan - 4 Jan](https://www.expedia.co.uk/Hotel-Search?regionId=6222968&startDate=2026-01-02&endDate=2026-01-04&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Panama Canal Zone 4-star hotels ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/877d081d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/6010dc9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout curtains, soundproofing](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/3873c049.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/da7a9306.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Crowne Plaza Panama Airport by IHG [](https://www.expedia.co.uk/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information) Tocumen 8.4/10 Very good (2331) "Beautiful lobby, friendly staff, clean room" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Kwai £90 includes taxes & fees 31 Dec - 1 Jan 2026 [](https://www.expedia.co.uk/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/4aee4896.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/bc945d5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Snack bar](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/4e8feb51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Junior Double Room | Premium bedding, down duvets, free minibar, in-room safe](https://images.trvl-media.com/lodging/92000000/92000000/91995600/91995575/7ab63fa0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Megapolis Hotel Panamá [](https://www.expedia.co.uk/Panama-City-Hotels-Megapolis-Hotel-Panama.h91995575.Hotel-Information) San Francisco 8.4/10 Very good (1302) "Best hotel I ever stayed" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Latoya £191 includes taxes & fees 3 Jan - 4 Jan 2026 [](https://www.expedia.co.uk/Panama-City-Hotels-Megapolis-Hotel-Panama.h91995575.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/10000000/9680000/9675300/9675263/83f7ceed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/10000000/9680000/9675300/9675263/1db36322.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/10000000/9680000/9675300/9675263/d548be4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Presidential Suite, City View | Terrace/patio](https://images.trvl-media.com/lodging/10000000/9680000/9675300/9675263/44769fa0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Las Americas Golden Tower Panama [](https://www.expedia.co.uk/Panama-City-Hotels-Las-Americas-Golden-Tower-Panama.h9675263.Hotel-Information) San Francisco 9.0/10 Wonderful (1007) "I loved my stay! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jenniffer Gonzalez De La £123 includes taxes & fees 18 Jan - 19 Jan 2026 [](https://www.expedia.co.uk/Panama-City-Hotels-Las-Americas-Golden-Tower-Panama.h9675263.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/b61be540.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/e3f1253f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 7:00 AM to 8:00 PM, pool umbrellas](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/9eaa509a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/38485558.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Marriott Panama Hotel [](https://www.expedia.co.uk/Panama-City-Hotels-Marriott-Panama-Hotel.h6099287.Hotel-Information) Panama City 9.0/10 Wonderful (1008) "Great hotel and staff!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Catherine £131 includes taxes & fees 2 Jan - 3 Jan 2026 [](https://www.expedia.co.uk/Panama-City-Hotels-Marriott-Panama-Hotel.h6099287.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/8000000/7060000/7050600/7050512/aad97f9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/8000000/7060000/7050600/7050512/b119cb62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/8000000/7060000/7050600/7050512/d813f542.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/8000000/7060000/7050600/7050512/a2ab1d01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Novotel Panama City [](https://www.expedia.co.uk/Panama-City-Hotels-Novotel-Panama-City.h7050512.Hotel-Information) Bella Vista 9.2/10 Wonderful (1042) "Great service, big room, solid breakfasts.. all at good price." ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Nicholas £89 includes taxes & fees 10 Jan - 11 Jan 2026 [](https://www.expedia.co.uk/Panama-City-Hotels-Novotel-Panama-City.h7050512.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/76000000/75290000/75284700/75284683/e86f18bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down duvets, Select Comfort beds, in-room safe](https://images.trvl-media.com/lodging/76000000/75290000/75284700/75284683/59ad07fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/76000000/75290000/75284700/75284683/d64fb02c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/76000000/75290000/75284700/75284683/f8325321.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Studio Coliving [](https://www.expedia.co.uk/Panama-City-Hotels-Studio-Coliving.h75284683.Hotel-Information) Bella Vista 7.8/10 Good (585) "Staff very helpful " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jean [](https://www.expedia.co.uk/Panama-City-Hotels-Studio-Coliving.h75284683.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1090000/1082800/1082793/067e7d25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast, lunch, dinner served; sushi ](https://images.trvl-media.com/lodging/2000000/1090000/1082800/1082793/32027b12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Double Room, 2 Double Beds, Sea View | Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/2000000/1090000/1082800/1082793/40a2c17a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/2000000/1090000/1082800/1082793/c59b4539.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Decapolis Hotel Panama City [](https://www.expedia.co.uk/Panama-City-Hotels-Decapolis-Hotel-Panama-City.h1082793.Hotel-Information) San Francisco 8.6/10 Excellent (1460) "Excellent stay. Wonderful staff, good location and excellent breakfast" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael £90 includes taxes & fees 8 Jan - 9 Jan 2026 [](https://www.expedia.co.uk/Panama-City-Hotels-Decapolis-Hotel-Panama-City.h1082793.Hotel-Information) ![Outdoor pool, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/9000000/8220000/8217000/8216939/803aefa9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/9000000/8220000/8217000/8216939/94455d61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property – evening/night](https://images.trvl-media.com/lodging/9000000/8220000/8217000/8216939/49d1f8ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/9000000/8220000/8217000/8216939/7d8fcf8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ramada Plaza by Wyndham Panama Punta Pacifica [](https://www.expedia.co.uk/Panama-City-Hotels-Ramada-Plaza-By-Wyndham-Panama-Punta-Pacifica.h8216939.Hotel-Information) San Francisco 9.6/10 Exceptional (1124) "The hotel is in a great location in Panama. Great amenities excellent breakfast." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Maria £80 includes taxes & fees 5 Jan - 6 Jan 2026 [](https://www.expedia.co.uk/Panama-City-Hotels-Ramada-Plaza-By-Wyndham-Panama-Punta-Pacifica.h8216939.Hotel-Information) ![Front of property – evening/night](https://images.trvl-media.com/lodging/7000000/6420000/6417200/6417143/19e6fda8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/7000000/6420000/6417200/6417143/b5b821ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch served; local and international cuisine, garden views ](https://images.trvl-media.com/lodging/7000000/6420000/6417200/6417143/c3192737.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/7000000/6420000/6417200/6417143/06af8af9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### American Trade Hotel [](https://www.expedia.co.uk/Panama-City-Hotels-American-Trade-Hotel.h6417143.Hotel-Information) Casco Viejo 9.4/10 Exceptional (607) "Excellent service and great rooms on a beautiful and historical building" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Manuel [](https://www.expedia.co.uk/Panama-City-Hotels-American-Trade-Hotel.h6417143.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/179e52b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/25adc131.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment room(s), sauna, hot tub, Turkish bath/hammam](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/58ea7ce3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Couples treatment room(s), sauna, hot tub, Turkish bath/hammam](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/19f9d9c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sheraton Grand Panama [](https://www.expedia.co.uk/Panama-City-Hotels-Sheraton-Grand-Panama.h1161.Hotel-Information) San Francisco 8.6/10 Excellent (995) "Was amazing food was delicious and stay was great " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amanda £110 includes taxes & fees 9 Jan - 10 Jan 2026 [](https://www.expedia.co.uk/Panama-City-Hotels-Sheraton-Grand-Panama.h1161.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/97000000/96830000/96825200/96825193/75048cd3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/97000000/96830000/96825200/96825193/913328f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/97000000/96830000/96825200/96825193/0ef1d297.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Casino](https://images.trvl-media.com/lodging/97000000/96830000/96825200/96825193/90ced08c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Waymore Hotel Spa & Casino [](https://www.expedia.co.uk/Panama-City-Hotels-Waymore-Hotel-Spa-Casino.h96825193.Hotel-Information) Bella Vista 9.0/10 Wonderful (624) "Very great hotel and service " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Prakash £81 includes taxes & fees 18 Jan - 19 Jan 2026 [](https://www.expedia.co.uk/Panama-City-Hotels-Waymore-Hotel-Spa-Casino.h96825193.Hotel-Information) ![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/5000000/4320000/4316400/4316336/e7c38de7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/5000000/4320000/4316400/4316336/1cf4d9ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/5000000/4320000/4316400/4316336/70833eb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4320000/4316400/4316336/b76cac34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Panama Metromall [](https://www.expedia.co.uk/San-Miguelito-Hotels-Courtyard-By-Marriott-Panama-Metromall.h4316336.Hotel-Information) Cerro Viento 8.8/10 Excellent (1005) "The hotel is conveniently close to the airport and shopping centres. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Samantha £89 includes taxes & fees 8 Jan - 9 Jan 2026 [](https://www.expedia.co.uk/San-Miguelito-Hotels-Courtyard-By-Marriott-Panama-Metromall.h4316336.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/7000000/6070000/6068400/6068325/a9dd3e38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/7000000/6070000/6068400/6068325/b99d0fb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/7000000/6070000/6068400/6068325/1b7439f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/7000000/6070000/6068400/6068325/8226ac87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Panama Distrito Financiero by IHG [](https://www.expedia.co.uk/Panama-City-Hotels-Holiday-Inn-Panama-Distrito-Financiero.h6068325.Hotel-Information) Bella Vista 8.8/10 Excellent (1004) "Clean room , friendly staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Junique £69 includes taxes & fees 16 Jan - 17 Jan 2026 [](https://www.expedia.co.uk/Panama-City-Hotels-Holiday-Inn-Panama-Distrito-Financiero.h6068325.Hotel-Information) ![47-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/3165768f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 Queen Bed | Minibar, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/58d3a2eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Presidential Suite, 1 King Bed, Jetted Tub | Terrace/patio](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/09deaa1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/16000000/15690000/15683600/15683502/w6390h4261x0y0-9ab7a08c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Central Hotel Panama Casco Viejo [](https://www.expedia.co.uk/Panama-City-Hotels-Central-Hotel-Panama-Casco-Viejo.h15683502.Hotel-Information) Casco Viejo 9.2/10 Wonderful (1001) "Nice hotel in the historic center, excellent location for sightseeing and walking around at night." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Antonio £234 includes taxes & fees 25 Dec - 26 Dec [](https://www.expedia.co.uk/Panama-City-Hotels-Central-Hotel-Panama-Casco-Viejo.h15683502.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/2000000/1150000/1145700/1145666/7dd302e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/2000000/1150000/1145700/1145666/899e3d45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/2000000/1150000/1145700/1145666/6d66fb78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Room, 1 King Bed with Sofa bed, City View | Premium bedding, down duvets, minibar, in-room safe](https://images.trvl-media.com/lodging/2000000/1150000/1145700/1145666/495ed44b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Panama Multiplaza Mall [](https://www.expedia.co.uk/Panama-City-Hotels-Courtyard-By-Marriott-Panama-Multiplaza-Mall.h1145666.Hotel-Information) San Francisco 9.0/10 Wonderful (1001) "Staff was very helpful. Great location." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John £82 includes taxes & fees 10 Jan - 11 Jan 2026 [](https://www.expedia.co.uk/Panama-City-Hotels-Courtyard-By-Marriott-Panama-Multiplaza-Mall.h1145666.Hotel-Information) ![Outdoor pool, open 6:00 AM to 11:00 PM, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/39000000/38750000/38742100/38742070/5bdfb47e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast ](https://images.trvl-media.com/lodging/39000000/38750000/38742100/38742070/a14793c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed with Sofa bed, Ocean View | Egyptian cotton sheets, premium bedding, minibar, in-room safe](https://images.trvl-media.com/lodging/39000000/38750000/38742100/38742070/8b731fa0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/39000000/38750000/38742100/38742070/db15307b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Residence Inn by Marriott Panama City [](https://www.expedia.co.uk/Panama-City-Hotels-Residence-Inn-By-Marriott-Panama-City.h38742070.Hotel-Information) San Francisco 9.0/10 Wonderful (542) "It's location is close to everything. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sharon £138 includes taxes & fees 10 Jan - 11 Jan 2026 [](https://www.expedia.co.uk/Panama-City-Hotels-Residence-Inn-By-Marriott-Panama-City.h38742070.Hotel-Information) ![Minibar, in-room safe, desk, blackout curtains](https://images.trvl-media.com/lodging/112000000/111850000/111843300/111843270/w5998h4000x0y0-cb1ce236.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/112000000/111850000/111843300/111843270/a14c580c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Minibar, in-room safe, desk, blackout curtains](https://images.trvl-media.com/lodging/112000000/111850000/111843300/111843270/da7a91a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/112000000/111850000/111843300/111843270/c2d235d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Regency Panama City [](https://www.expedia.co.uk/Panama-City-Hotels-Hyatt-Regency-Panama-City.h111843270.Hotel-Information) Bella Vista 10/10 Exceptional (131) "Great hotel fair price" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Santiago £128 includes taxes & fees 4 Jan - 5 Jan 2026 [](https://www.expedia.co.uk/Panama-City-Hotels-Hyatt-Regency-Panama-City.h111843270.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/101000000/100630000/100620400/100620363/8c9eeca6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/101000000/100630000/100620400/100620363/3bea3d66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/101000000/100630000/100620400/100620363/6ae0cc51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Suite | Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/101000000/100630000/100620400/100620363/66a802aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel San Felipe [](https://www.expedia.co.uk/Panama-City-Hotels-Hotel-San-Felipe.h100620363.Hotel-Information) Casco Viejo 9.4/10 Exceptional (254) "Nice hotel, perfect area in the old quarter. Clean, comfortable, great staff. Highly recommend!" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Neil £95 includes taxes & fees 7 Jan - 8 Jan 2026 [](https://www.expedia.co.uk/Panama-City-Hotels-Hotel-San-Felipe.h100620363.Hotel-Information) ![Daily full breakfast for a fee](https://images.trvl-media.com/lodging/72000000/71140000/71136000/71135966/02cb9f51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/72000000/71140000/71136000/71135966/1a46103c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property – evening/night](https://images.trvl-media.com/lodging/72000000/71140000/71136000/71135966/adda9f81.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 Queen Bed (Casco) | Premium bedding, down duvets, pillow-top beds, minibar](https://images.trvl-media.com/lodging/72000000/71140000/71136000/71135966/5584b8b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel La Compañía Casco Antiguo [](https://www.expedia.co.uk/Panama-City-Hotels-Hotel-La-Compania.h71135966.Hotel-Information) Casco Viejo 9.8/10 Exceptional (258) "Great location!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Erik £330 includes taxes & fees 6 Jan - 7 Jan 2026 [](https://www.expedia.co.uk/Panama-City-Hotels-Hotel-La-Compania.h71135966.Hotel-Information) ![2 outdoor pools, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/1000000/810000/809200/809149/23e8ad44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/810000/809200/809149/b6d8aae1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/810000/809200/809149/93c6a3dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/1000000/810000/809200/809149/53267d7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Radisson Hotel Panama Canal [](https://www.expedia.co.uk/Amador-Hotels-Radisson-Hotel-Panama-Canal.h809149.Hotel-Information) Amador 8.4/10 Very good (1004) "Wonderful staff and easy checkin!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kristin £66 includes taxes & fees 7 Jan - 8 Jan 2026 [](https://www.expedia.co.uk/Amador-Hotels-Radisson-Hotel-Panama-Canal.h809149.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Panama-Canal-Zone-Hotels.s40-0-d6222968.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Panama-Canal-Zone-Hotels.s40-0-d6222968.Travel-Guide-Filter-Hotels) ## Explore similar 5-star hotels Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Panama Canal Zone. ![Hotel Riu Plaza Panama](https://images.trvl-media.com/lodging/4000000/3910000/3900400/3900395/1eaf88f5_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Riu Plaza Panama Calle 50, Urb. Marbella Panama City Panama £89 12 Jan - 13 Jan 2026 includes taxes & fees 9/10 Wonderful! (4,696 reviews) [](https://expedia.co.uk/Panama-City-Hotels-Hotel-Riu-Plaza-Panama.h3900395.Hotel-Information) ![Waldorf Astoria Panama](https://images.trvl-media.com/lodging/5000000/4960000/4952100/4952056/e7e98c5e_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Waldorf Astoria Panama 47th St. & Uruguay Street Panama City Panama £180 10 Jan - 11 Jan 2026 includes taxes & fees 8.8/10 Excellent! (1,002 reviews) [](https://expedia.co.uk/Panama-City-Hotels-Waldorf-Astoria-Panama.h4952056.Hotel-Information) ![W Panama](https://images.trvl-media.com/lodging/22000000/21320000/21314100/21314035/5dc0b3d1_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### W Panama Calle Aquilino de la Guardia & Calle 50 Panama City £169 3 Jan - 4 Jan 2026 includes taxes & fees 8.8/10 Excellent! (1,005 reviews) [](https://expedia.co.uk/Panama-City-Hotels-W-Panama.h21314035.Hotel-Information) Still don't see what you're looking for? [See all properties in Panama Canal Zone.](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=25%2F12%2F2025&endDate=26%2F12%2F2025®ionId=6222968&star=40) You can also use these popular filters to refine your search. [Pool](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=25%2F12%2F2025&endDate=26%2F12%2F2025®ionId=6222968&star=40&star=40&amenities=POOL)[Spa](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=25%2F12%2F2025&endDate=26%2F12%2F2025®ionId=6222968&star=40&star=40&amenities=SPA_ON_SITE)[Hot tub](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=25%2F12%2F2025&endDate=26%2F12%2F2025®ionId=6222968&star=40&star=40&amenities=HOT_TUB)[Breakfast included](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=25%2F12%2F2025&endDate=26%2F12%2F2025®ionId=6222968&star=40&star=40&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=25%2F12%2F2025&endDate=26%2F12%2F2025®ionId=6222968&star=40&star=40&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about Panama Canal Zone Explore the relaxing area of Panama Canal Zone—rainforests, golf courses and popular sights like Albrook Shopping Mall. [See all hotels in Panama Canal Zone](https://www.expedia.co.uk/Hotel-Search?startDate=2026-01-07&endDate=2026-01-08&adults=2®ionId=6222968) ![0_BU000512](https://images.trvl-media.com/place/6222968/089e46e9-cc78-4d6b-b43a-af08a95dd797.jpg) ## Top Panama Canal Zone Hotel Reviews ![Summit Rainforest & Golf Resort](https://images.trvl-media.com/lodging/4000000/3010000/3006200/3006144/a96760ad_y.jpg) ### Summit Rainforest & Golf Resort 10/10 Excellent "Great place to scape for a weekend " [](https://expedia.co.uk/Ancon-Hotels-Summit-Rainforest-Golf-Resort.h3006144.Hotel-Information) ![Novotel Panama City](https://images.trvl-media.com/lodging/8000000/7060000/7050600/7050512/aad97f9d_y.jpg) ### Novotel Panama City 10/10 Excellent "Cleanliness of the property and friendly staff." [](https://expedia.co.uk/Panama-City-Hotels-Novotel-Panama-City.h7050512.Hotel-Information) ![Decapolis Hotel Panama City](https://images.trvl-media.com/lodging/2000000/1090000/1082800/1082793/067e7d25_y.jpg) ### Decapolis Hotel Panama City 10/10 Excellent "Clean room… amazing staff, breakfast was delicious our favorite hotel always " [](https://expedia.co.uk/Panama-City-Hotels-Decapolis-Hotel-Panama-City.h1082793.Hotel-Information) ![Crowne Plaza Panama Airport by IHG](https://images.trvl-media.com/lodging/9000000/8840000/8836200/8836117/877d081d_y.jpg) ### Crowne Plaza Panama Airport by IHG 10/10 Excellent "Yes to both" [](https://expedia.co.uk/Tocumen-Hotels-Crowne-Plaza-Panama-Airport.h8836117.Hotel-Information) ![Marriott Panama Hotel](https://images.trvl-media.com/lodging/7000000/6100000/6099300/6099287/b61be540_y.jpg) ### Marriott Panama Hotel 10/10 Excellent "Great hotel and staff!" [](https://expedia.co.uk/Panama-City-Hotels-Marriott-Panama-Hotel.h6099287.Hotel-Information) ![Las Americas Golden Tower Panama](https://images.trvl-media.com/lodging/10000000/9680000/9675300/9675263/83f7ceed_y.jpg) ### Las Americas Golden Tower Panama 10/10 Excellent "It was a very nice stay. The room is nice, organized and clean with a great view of the city. The blankets are a little too warm and we wished for a lighter blankets. Breakfast buffet was very good with many food choices and best custom eggs cooked tailored to our demands. Uber to Casco Viejo was cheap. Uber to PTY airport was $17\. Views from the hotel are beautiful. Pool was the best, clean, lots of lights, cozy and just what we needed to swim after long day of sightseing Panama canal, boat tour to Monkey Islands, long walk along Cinta Costera and dinner with friends on the 5th floor of Golden tower." [](https://expedia.co.uk/Panama-City-Hotels-Las-Americas-Golden-Tower-Panama.h9675263.Hotel-Information) ![Dreams Playa Bonita Panama - All Inclusive](https://images.trvl-media.com/lodging/13000000/12450000/12445600/12445554/7c338453_y.jpg) ### Dreams Playa Bonita Panama - All Inclusive 10/10 Excellent "Excellent service, good even more so. The property is clean, however the chairs and curtains show their age in a major way. Staff are friendly and every interaction was pleasant. We would definitely return to this resort. " [](https://expedia.co.uk/Panama-City-Hotels-Dreams-Playa-Bonita-Panama.h12445554.Hotel-Information) ![Sheraton Grand Panama](https://images.trvl-media.com/lodging/1000000/10000/1200/1161/179e52b4_y.jpg) ### Sheraton Grand Panama 10/10 Excellent "Yes" [](https://expedia.co.uk/Panama-City-Hotels-Sheraton-Grand-Panama.h1161.Hotel-Information) ![Hotel El Panama by Faranda Grand, a member of Radisson Individuals](https://images.trvl-media.com/lodging/1000000/10000/7200/7164/cfc3400a_y.jpg) ### Hotel El Panama by Faranda Grand, a member of Radisson Individuals 10/10 Excellent "Fresh fruits, eggs, bread everything. Very good!" [](https://expedia.co.uk/Panama-City-Hotels-Hotel-El-Panama-By-Faranda-Grand.h7164.Hotel-Information) ## Find out more about Panama Canal Zone ## Frequently asked questions ### What are the best 4-star hotels in Panama Canal Zone? ### How much does it cost to stay in a 4-star hotel in Panama Canal Zone? > - Search for the lowest price from £89 ### What's the difference between 5-star and 4-star hotels in Panama Canal Zone?