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Featured Florida Keys 4 Star Hotels

See all 394 Hotels in Florida Keys
Margaritaville Key West Resort & Marina

Margaritaville Key West Resort & Marina

245 Front Street, Key West
4.0 out of 5.0
4.0 out of 5 (46 reviews)
Staff was fantastic. Rooms were just okay. We told we would have a room with a view and it didn't turn out that way. In fact I paid for two rooms and we were not put next door to each other.
  12 Oct 2017

£160

£160
Casa Marina, A Waldorf Astoria Resort

Casa Marina, A Waldorf Astoria Resort

1500 Reynolds Street, Key West
4.0 out of 5.0
4.1 out of 5 (987 reviews)
Nice hotel. Nice breakfast. Poor beach. Rooms good but need bathroom remodelation. Excellent worker.
  6 Sep 2017

£173

£173
Pier House Resort & Spa

Pier House Resort & Spa

1 Duval St, Key West
4.0 out of 5.0
4.5 out of 5 (655 reviews)
Great location! Was awesome to have a beach and pool!
  20 Oct 2017

£219

£219
La Concha Hotel & Spa

La Concha Hotel & Spa

430 Duval St, Key West
4.0 out of 5.0
4.0 out of 5 (608 reviews)
Great hotel in the center of town near shops and rThe room was lovely and clean. The bed was very comfortable The View out the window is lovely. The staff was very polite. And the pool on the second floor was great
  16 Oct 2017

£157

£157
Southernmost Beach Resort

Southernmost Beach Resort

1319 Duval Street, Key West
4.0 out of 5.0
4.5 out of 5 (1,495 reviews)
Wonderful resort within walking distance of little shops and other nice places to eat. Plenty of other activities available for booking at the tour desk on the island. Would definitely come back.
  20 Oct 2017

£210

£210
The Perry Hotel Key West

The Perry Hotel Key West

7001 Shrimp Road, Key West
4.0 out of 5.0
4.6 out of 5 (33 reviews)
Hotel That Made You Feel Like You Were In a B & DEverything about this hotel just worked. Really good family environment. Fantastic room. Great pool. Really friendly staff. Met one of the owners, Bruce, earlier in the AM one day who made you feel like you were his personal guest. Location is fantastic, with just a few minutes car ride to get into ...
  30 Aug 2017

£150

£150
Hyatt Centric Key West Resort and Spa

Hyatt Centric Key West Resort and Spa

601 Front St, Key West
4.0 out of 5.0
4.5 out of 5 (685 reviews)
Found a winnerVery nice place to stay. Staff was unbelievably friendly, and willing to help in anyway. Food was great, and views of the ocean from the pool were amazing. We did have a bad experience with the elevator, but shouldn’t be held against them. I would definitely go back!
  20 Oct 2017

£152

£152
Tranquility Bay Beachfront Hotel and Resort

Tranquility Bay Beachfront Hotel and Resort

2600 Overseas Hwy, Marathon
4.0 out of 5.0
4.5 out of 5 (478 reviews)
A Beautiful HotelWe spent a wonderful weekend. It was exactly like I saw in Expedia Web page. It is beautiful, clean and comfortable hotel with a beautiful sight on the sea. The staff is friendly a
  11 Sep 2017

£148

£148
The Reach, A Waldorf Astoria Resort

The Reach, A Waldorf Astoria Resort

1435 Simonton Street, Key West
4.0 out of 5.0
4.0 out of 5 (788 reviews)
PerfectIt was everything I was looking for. I had an excellent stay.
  16 Oct 2017

£193

£193
The Gates Hotel Key West

The Gates Hotel Key West

3824 N Roosevelt Blvd, Key West
4.0 out of 5.0
4.3 out of 5 (318 reviews)
Nice hotel within minutes of downtownThe location is perfect because it is within minutes of everything. The staff is great and very professional. My boyfriend was worried he lost his vacation mug, but the staff located it and put it aside for him because they knew who it was for. They even offer a free shuttle service to and from downtown, ...
  12 Oct 2017

£138

£138
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Pocket Guide: 4 stars Hotels in Florida Keys

4 Star Luxury in the Florida Keys

You’ll find a great selection of four-star hotels in Florida Keys, each reflecting its very own character, charm and ethos. Whatever the style, whether it’s an elegant resort and spa, contemporary seaside hotel or plush cottage, most four-star accommodation in the Florida Keys are close to the water, and you wouldn’t want it any other way. For the true magic of the Florida Keys is in its beaches, coral reefs and Gulf of Mexico views.

Where Are Florida Keys’ 4 Star Hotels?

Key West is home to most of Florida Keys’ four-star resorts. With Mallory Square Plaza, beautiful beaches, its historic old town and a world-class golf course, Key West is one of the most idyllic places to stay.

You’ll also find luxury accommodation on Islamorada, as well as the lesser-visited islands of Little Torch Key and the romantic Marathon Island. With swimming pools, sea views and palm trees (not to mention the spas and fine-dining restaurants) it will be hard to drag yourself away from your four-star hotel to explore.

Enjoy the Florida Keys in Style

Looking out to sea is one thing, but for an experience you won’t quickly forget, get out on to the water in comfort aboard your very own yacht for the day and explore hidden beaches and clear coves. You can charter catamarans, sail or motorboats from many of the islands’ marinas or through your hotel concierge. Anglers, whether novices or long-time enthusiasts, will find the waters teeming with big-game fish. Or why not learn a new water sport? Scuba-diving courses are a wonderful experience and will introduce you to a whole new world beneath the waves.

If you’re more of a land-lubber than a budding mariner, hunker down by one of the oasis-like pools in your hotel with a fruit rum cocktail in hand and ease in to your stay. Museums such as the Ernest Hemingway House, art galleries and cigar rooms are local institutions and give you an insight into the culture and history of the Florida Keys.

Recently booked Florida Keys hotels

The Gates Hotel Key West
4.0 out of 5.0
Last booking: 1 hour ago