A beach with palm trees, people relaxing on chairs, and colorful kayaks.

Compare and book 4 Star hotels in Florida Keys, United States of America

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Check availability on Florida Keys 4 Star Hotels

Tonight
13 Aug - 14 Aug
Tomorrow
14 Aug - 15 Aug
This weekend
14 Aug - 16 Aug
Next weekend
21 Aug - 23 Aug

Our top choices for Florida Keys 4-star hotels

1. Hawks Cay Resort

Hawks Cay Resort
Marathon
United States
Aida
£218
includes taxes & fees
24 Aug - 25 Aug
Hawks Cay Resort

2. Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton
Key Largo
United States
Jennifer
£252
includes taxes & fees
24 Aug - 25 Aug
Baker's Cay Resort Key Largo, Curio Collection by Hilton

3. Amara Cay Resort

Amara Cay Resort
Matecumbe
United States
Estefani
£186
includes taxes & fees
19 Aug - 20 Aug
Amara Cay Resort

4. Reefhouse Resort & Marina

Reefhouse Resort & Marina
Key Largo
United States
Matt
£212
includes taxes & fees
19 Aug - 20 Aug
Reefhouse Resort & Marina

5. Islander Resort

Islander Resort
Matecumbe
United States
Chris
£267
includes taxes & fees
20 Aug - 21 Aug
Islander Resort

6. Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
Rock Harbor
United States
Nicole
£240
includes taxes & fees
2 Sept - 3 Sept
Playa Largo Resort & Spa, Autograph Collection

7. Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
Islamorada
United States
Ana
£227
includes taxes & fees
7 Sept - 8 Sept
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

8. Tranquility Bay Beachfront Hotel and Resort

Tranquility Bay Beachfront Hotel and Resort
Marathon
United States
Barbara
£220
includes taxes & fees
13 Sept - 14 Sept
Tranquility Bay Beachfront Hotel and Resort

9. Faro Blanco Resort Marathon Florida Keys, Curio by Hilton

Faro Blanco Resort Marathon Florida Keys, Curio by Hilton
Marathon
United Kingdom
joanne
£184
includes taxes & fees
7 Sept - 8 Sept
Faro Blanco Resort Marathon Florida Keys, Curio by Hilton

10. La Siesta Resort & Villas

La Siesta Resort & Villas
Matecumbe
United States
Brianne
£176
includes taxes & fees
25 Aug - 26 Aug
La Siesta Resort & Villas

11. Villas At Hawks Cay Resort

Villas At Hawks Cay Resort
Marathon
United States
Elise
£632
includes taxes & fees
23 Aug - 24 Aug
Villas At Hawks Cay Resort

12. Grassy Flats Resort & Beach Club

Grassy Flats Resort & Beach Club
Marathon
United Kingdom
Katherine
£161
includes taxes & fees
19 Aug - 20 Aug
Grassy Flats Resort & Beach Club

13. The Islands of Islamorada

The Islands of Islamorada
Matecumbe
United States
Christian
£340
includes taxes & fees
24 Aug - 25 Aug
The Islands of Islamorada

14. Marlin Bay Resort & Marina

Marlin Bay Resort & Marina
Marathon
United States
Chardell
Marlin Bay Resort & Marina

15. Waterfront Luxury Villa

Waterfront Luxury Villa
Marathon Shores
Waterfront Luxury Villa
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Florida Keys.
Cheeca Lodge & Spa

Cheeca Lodge & Spa

81801 Overseas Highway, Mile Marker 82 Islamorada FL
£178
18 Aug - 19 Aug
includes taxes & fees
9.2/10 Wonderful! (1,379 reviews)
Cheeca Lodge & Spa
Isla Bella Beach Resort & Spa

Isla Bella Beach Resort & Spa

1 Knights Key Boulevard Marathon FL
£232
16 Aug - 17 Aug
includes taxes & fees
Isla Bella Beach Resort & Spa
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Florida Keys

Snorkel crystal-clear waters teeming with colourful fish, then feast on fresh-caught lobster at a laid-back waterfront shack. Drive the scenic Overseas Highway, stopping at Key West's Ernest Hemingway Home and Dry Tortugas National Park for island adventures.

See all hotels in Florida Keys
A beach with palm trees, people relaxing on chairs, and colorful kayaks.

Top Florida Keys Hotel Reviews

Hawks Cay Resort

Hawks Cay Resort

8/10 Good
"The beauty of the resort takes you away, and reminds you that this is paradise."
Craig 5-night trip
Posted 16 hours ago
Hawks Cay Resort
Islander Resort

Islander Resort

10/10 Excellent
"Gran limpieza. Personal atento y profesional . Fantástico lugar para descansar."
Guillermo 2-night trip
Posted 1 day ago
Islander Resort
Tranquility Bay Beachfront Hotel and Resort

Tranquility Bay Beachfront Hotel and Resort

10/10 Excellent
"awesome resort in Marathon, beach, pool and all the resort has to offer. Great location"
Barbara 3-night trip
Posted 1 day ago
Tranquility Bay Beachfront Hotel and Resort

Find out more about Florida Keys

Pocket Guide: 4 Stars Hotels in Florida Keys

4 Star Luxury in the Florida Keys

You’ll find a great selection of four-star hotels in Florida Keys, each reflecting its very own character, charm and ethos. Whatever the style, whether it’s an elegant resort and spa, contemporary seaside hotel or plush cottage, most four-star accommodation in the Florida Keys are close to the water, and you wouldn’t want it any other way. For the true magic of the Florida Keys is in its beaches, coral reefs and Gulf of Mexico views.

Where Are Florida Keys’ 4 Star Hotels?

Key West is home to most of Florida Keys’ four-star resorts. With Mallory Square Plaza, beautiful beaches, its historic old town and a world-class golf course, Key West is one of the most idyllic places to stay.

You’ll also find luxury accommodation on Islamorada, as well as the lesser-visited islands of Little Torch Key and the romantic Marathon Island. With swimming pools, sea views and palm trees (not to mention the spas and fine-dining restaurants) it will be hard to drag yourself away from your four-star hotel to explore.

Enjoy the Florida Keys in Style

Looking out to sea is one thing, but for an experience you won’t quickly forget, get out on to the water in comfort aboard your very own yacht for the day and explore hidden beaches and clear coves. You can charter catamarans, sail or motorboats from many of the islands’ marinas or through your hotel concierge. Anglers, whether novices or long-time enthusiasts, will find the waters teeming with big-game fish. Or why not learn a new water sport? Scuba-diving courses are a wonderful experience and will introduce you to a whole new world beneath the waves.

If you’re more of a land-lubber than a budding mariner, hunker down by one of the oasis-like pools in your hotel with a fruit rum cocktail in hand and ease in to your stay. Museums such as the Ernest Hemingway House, art galleries and cigar rooms are local institutions and give you an insight into the culture and history of the Florida Keys.

Frequently asked questions

What are the best 4-star hotels in Florida Keys?
You'll discover a variety of 4-star hotels in Florida Keys, including in Key Largo. Playa Largo Resort & Spa, Autograph Collection is a customer favourite in this city that offers a tennis court and a sauna. Another stay that rates highly with travellers is Bakers Cay Resort Key Largo, Curio Collection by Hilton. Dining romance packages and private picnic options help make it their preferred choice.
How much does it cost to stay in a 4-star hotel in Florida Keys?
To find a 4-star hotel in Florida Keys that fits your budget, take advantage of Expedia's handy search filters. Take a look at the availability during your holiday dates and use our pricing filter to set your maximum rate. You can also sort your results by the most affordable retreat first.
  • Search for the lowest price from £178
What's the difference between 5-star and 4-star hotels in Florida Keys?
Offering a welcoming traveller experience and upmarket décor, 4-star hotels are an excellent option for your Florida Keys getaway. These types of accommodation generally feature loads of useful amenities that make it easy to unpack and relax — think pillowtop mattresses, pools and restaurants. Or live the high life at a 5-star hotel designed to spoil you with high-end perks and amenities. Concierge assistance, premium toiletries and fine dining are typically included at these deluxe properties.

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