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Check prices on hotels in Florida Keys

Tonight Tonight 22 Jun - 23 Jun
This weekend This weekend 22 Jun - 24 Jun
Next weekend Next weekend 29 Jun - 1 Jul

Featured Florida Keys 4 Star Hotels

See all 848 properties in Florida Keys
Southernmost Beach Resort

Southernmost Beach Resort

1319 Duval Street, Key West
  • Free cancellation
  • Reserve now, pay when you stay
4.0 out of 5.0
 
 
4.5 out of 5 (3,470 reviews)
Great resort! We enjoyed it!We liked the room and the facilities as well as the location. The rooms were nice and the pool areas were great. The spa was small but sufficient as we got a couples massage that was outstanding. The only issue is the beach area was small and open to the public. The nice pools made it up for us but ...
21 Jun 2018

Southernmost Beach Resort£165

Southernmost Beach Resort£165
Oceans Edge Key West Resort, Hotel & Marina

Oceans Edge Key West Resort, Hotel & Marina

5950 Peninsular Avenue, Key West
  • Free cancellation
  • Reserve now, pay when you stay
4.0 out of 5.0
 
 
4.5 out of 5 (568 reviews)
Beautiful HotelThe hotel facade and hampton's style decorating is perfection, the grounds and facilities excellent. The location of the building that we stayed in was poor and far away from everything, try and avoid Building 4 if you can, access to everything from here is not thought through. The hotel reception ...
13 Jun 2018
Margaritaville Key West Resort & Marina

Margaritaville Key West Resort & Marina

245 Front Street, Key West
  • Free cancellation
  • Reserve now, pay when you stay
4.0 out of 5.0
 
 
4.3 out of 5 (311 reviews)
Highly recommendWe only stayed for a short time. Hotel was nice and clean. Staff was great, lots of amenities and right in the middle of everything.
16 Jun 2018

Margaritaville Key West Resort & Marina£184

Margaritaville Key West Resort & Marina£184
The Perry Hotel Key West

The Perry Hotel Key West

7001 Shrimp Road, Key West
  • Free cancellation
  • Reserve now, pay when you stay
4.0 out of 5.0
 
 
4.6 out of 5 (217 reviews)
Better than expectedOff the beaten path but a welcome change of pace with a great atmosphere. Industrial modern feel with great views of the marina. Very comfortable room. Staff friendly and accommodating. Restaraunt on site had an excellent Mahi sandwich. Definitely worth at least one meal while here. Would stay here ...
15 Jun 2018

The Perry Hotel Key West£119

The Perry Hotel Key West£119
24 North Hotel Key West

24 North Hotel Key West

3820 North Roosevelt Boulevard, Key West
  • Free cancellation
  • Reserve now, pay when you stay
4.0 out of 5.0
 
 
4.1 out of 5 (1,238 reviews)
Fair. O.K.Rust running down the shower towel rack can be easily fixed, but is not. Room not as clean as it should be. 3 great hotel staff members at desk. Young man not helpful. Pool area good and outside bar very nice. 1/2 price drinks appreciated (made real price reasonable). Just charge 1/2 prince to drink ...
4 Jun 2018
The Gates Hotel Key West

The Gates Hotel Key West

3824 N Roosevelt Blvd, Key West
  • Free cancellation
  • Reserve now, pay when you stay
4.0 out of 5.0
 
 
4.3 out of 5 (1,253 reviews)
Awesome hotel Free shuttle was awesome but still only a 5-10 min drive if we chose to drive into town ourselves. Room was clean, well decorated, and comfortable. It did have a little bit of a musty smell when we initially walked in but most likely from the humidity. Check in and check out was smooth. Pool and ...
19 Jun 2018

The Gates Hotel Key West£101

The Gates Hotel Key West£101
Pier House Resort & Spa

Pier House Resort & Spa

1 Duval St, Key West
  • Free cancellation
  • Reserve now, pay when you stay
4.0 out of 5.0
 
 
4.4 out of 5 (1,554 reviews)
Wonderful hotel with a beachGreat hotel with a beautiful beach and great amenities. Would definitely return to this resort and recommend it to friends
11 Jun 2018

Pier House Resort & Spa£201

Pier House Resort & Spa£201
Casa Marina, A Waldorf Astoria Resort

Casa Marina, A Waldorf Astoria Resort

1500 Reynolds Street, Key West
  • Free cancellation
  • Reserve now, pay when you stay
4.0 out of 5.0
 
 
4.2 out of 5 (2,199 reviews)
Classic luxury - modern amenitiesMr. Flagler knew what he was doing when he built the place. We had a king suite beach walkout and stepped right on to the sand. Room was laid out great, friendly staff, nice pool, easy to use water equipment and bikes etc. This is a higher end resort so you will pay for what you use - for example, ...
7 May 2018

Casa Marina, A Waldorf Astoria Resort£212

Casa Marina, A Waldorf Astoria Resort£212
The Marker Waterfront Resort Key West

The Marker Waterfront Resort Key West

200 William Street, Key West
  • Free cancellation
  • Reserve now, pay when you stay
4.0 out of 5.0
 
 
4.5 out of 5 (987 reviews)
Very nice resort right next to oceanThis was a great place! Clean and friendly and in a great location to walk everywhere!
20 Jun 2018

The Marker Waterfront Resort Key West£147

The Marker Waterfront Resort Key West£147
Tranquility Bay Beachfront Hotel and Resort

Tranquility Bay Beachfront Hotel and Resort

2600 Overseas Hwy, Marathon
  • Free cancellation
  • Reserve now, pay when you stay
4.0 out of 5.0
 
 
4.5 out of 5 (1,132 reviews)
Beautiful view from any angleSpacious and very clean No contact at all from management staff which was disappointing after 8 days stay Dining was overpriced Facilities were beautiful and lots to see and do in Marathon
3 May 2018
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Pocket Guide: 4 Stars Hotels in Florida Keys

4 Star Luxury in the Florida Keys

You’ll find a great selection of four-star hotels in Florida Keys, each reflecting its very own character, charm and ethos. Whatever the style, whether it’s an elegant resort and spa, contemporary seaside hotel or plush cottage, most four-star accommodation in the Florida Keys are close to the water, and you wouldn’t want it any other way. For the true magic of the Florida Keys is in its beaches, coral reefs and Gulf of Mexico views.

Where Are Florida Keys’ 4 Star Hotels?

Key West is home to most of Florida Keys’ four-star resorts. With Mallory Square Plaza, beautiful beaches, its historic old town and a world-class golf course, Key West is one of the most idyllic places to stay.

You’ll also find luxury accommodation on Islamorada, as well as the lesser-visited islands of Little Torch Key and the romantic Marathon Island. With swimming pools, sea views and palm trees (not to mention the spas and fine-dining restaurants) it will be hard to drag yourself away from your four-star hotel to explore.

Enjoy the Florida Keys in Style

Looking out to sea is one thing, but for an experience you won’t quickly forget, get out on to the water in comfort aboard your very own yacht for the day and explore hidden beaches and clear coves. You can charter catamarans, sail or motorboats from many of the islands’ marinas or through your hotel concierge. Anglers, whether novices or long-time enthusiasts, will find the waters teeming with big-game fish. Or why not learn a new water sport? Scuba-diving courses are a wonderful experience and will introduce you to a whole new world beneath the waves.

If you’re more of a land-lubber than a budding mariner, hunker down by one of the oasis-like pools in your hotel with a fruit rum cocktail in hand and ease in to your stay. Museums such as the Ernest Hemingway House, art galleries and cigar rooms are local institutions and give you an insight into the culture and history of the Florida Keys.

Recently booked Florida Keys hotels

Chesapeake Beach Resort
2.5 out of 5.0
Last booking: 59 minutes ago
Fairfield Inn and Suites by Marriott Key West
3.5 out of 5.0
Last booking: 1 hour ago
La Concha Hotel & Spa
4.0 out of 5.0
Last booking: 2 hours ago
The Southernmost Inn-Adults Only
2.5 out of 5.0
Last booking: 2 hours ago
Seashell Motel & Key West Hostel
1.5 out of 5.0
Last booking: 3 hours ago
Hyatt Residence Club Key West, Windward Pointe
3.5 out of 5.0
Last booking: 3 hours ago
Key West Marriott Beachside Hotel
3.5 out of 5.0
Last booking: 3 hours ago
The Marker Waterfront Resort Key West
4.0 out of 5.0
Last booking: 4 hours ago
Banana Bay Resort and Marina
2.5 out of 5.0
Last booking: 4 hours ago