Compare and book 4 Star hotels in Florida Keys, United States of America

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Check availability on Florida Keys 4 Star Hotels

Top Florida Keys 4 Star Hotels

Our top choices for Florida Keys 4-star hotels

Baker's Cay Resort Key Largo, Curio Collection by Hilton

4.0 star property
8.6 out of 10, Excellent, (1003)
"I would stay here again "
The price is £252
includes taxes & fees
2 Sept - 3 Sept
Baker's Cay Resort Key Largo, Curio Collection by Hilton

Amara Cay Resort

4.0 star property
9.0 out of 10, Wonderful, (1237)
"Always an amazing place to stay "
The price is £189
includes taxes & fees
1 Sept - 2 Sept
Amara Cay Resort

Islander Resort

4.0 star property
9.2 out of 10, Wonderful, (1002)
"The resort is perfect!!"
The price is £216
includes taxes & fees
21 Sept - 22 Sept
Islander Resort

Playa Largo Resort & Spa, Autograph Collection

4.5 star property
9.0 out of 10, Wonderful, (1003)
"Love this property and the food is amazing!"
The price is £240
includes taxes & fees
7 Sept - 8 Sept
Playa Largo Resort & Spa, Autograph Collection

Hawks Cay Resort

4.0 star property
8.0 out of 10, Very good, (1004)
"Great stay with family! Lots to do and plenty nearby for other dining and shopping options."
The price is £215
includes taxes & fees
11 Sept - 12 Sept
Hawks Cay Resort

Villas At Hawks Cay Resort

4.0 star property
8.6 out of 10, Excellent, (116)
"I loved my stay!"
Villas At Hawks Cay Resort

Faro Blanco Resort & Yacht Club Marathon, Curio by Hilton

4.0 star property
8.8 out of 10, Excellent, (1287)
"Great stay "
The price is £156
includes taxes & fees
8 Sept - 9 Sept
Faro Blanco Resort & Yacht Club Marathon, Curio by Hilton

La Siesta Resort & Villas

4.0 star property
8.6 out of 10, Excellent, (1008)
"perfect family hotel with a keys flare."
The price is £149
includes taxes & fees
8 Sept - 9 Sept
La Siesta Resort & Villas

Tranquility Bay Beachfront Hotel and Resort

4.0 star property
8.8 out of 10, Excellent, (1002)
"Excellent stay. "
The price is £234
includes taxes & fees
14 Sept - 15 Sept
Tranquility Bay Beachfront Hotel and Resort

The Islands of Islamorada

4.0 star property
9.8 out of 10, Exceptional, (66)
"Absolutely outstanding resort. Legitimate 5 star property. "
The price is £498
includes taxes & fees
3 Sept - 4 Sept
The Islands of Islamorada

Marlin Bay Resort & Marina

4.0 star property
Marlin Bay Resort & Marina

The Reef at Marathon, Florida Keys

4.0 star property
9.4 out of 10, Exceptional, (8)
"It’s always been my favorite. The villas fit all my needs. Fantastic location and friendly staff."
The Reef at Marathon, Florida Keys

Key Colony Beach Paradise

4.0 star property
10.0 out of 10, Exceptional, (4)
"We loved this property. The boat dock is so large and we really appreciate the bumpers to protect the boat. Plenty of seating around the pool. The afternoon sun really heats that side of the street so the pool was very warm - still refreshing. The beds are super comfortable and the house is laid out very well with plenty of room. We loved our stay!!!"
Key Colony Beach Paradise

The Caribbean Resort Coconut Palm North

4.0 star property
The Caribbean Resort Coconut Palm North
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Explore similar 5-star hotels

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Florida Keys

Discover the seaside area of Florida Keys—live music, beaches and top sights like Duval Street.

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Top Florida Keys Hotel Reviews

Frequently asked questions

What are the best 4-star hotels in Florida Keys?
You'll discover a variety of 4-star hotels in Florida Keys, including in Key Largo. Playa Largo Resort & Spa, Autograph Collection is a customer favourite in this city that offers a tennis court and a sauna. Another stay that rates highly with travellers is Bakers Cay Resort Key Largo, Curio Collection by Hilton. Dining romance packages and private picnic options help make it their preferred choice.
How much does it cost to stay in a 4-star hotel in Florida Keys?
To find a 4-star hotel in Florida Keys that fits your budget, take advantage of Expedia's handy search filters. Take a look at the availability during your holiday dates and use our pricing filter to set your maximum rate. You can also sort your results by the most affordable retreat first.

  • Search for the lowest price from £170

What's the difference between 5-star and 4-star hotels in Florida Keys?
Offering a welcoming traveller experience and upmarket décor, 4-star hotels are an excellent option for your Florida Keys getaway. These types of accommodation generally feature loads of useful amenities that make it easy to unpack and relax — think pillowtop mattresses, pools and restaurants. Or live the high life at a 5-star hotel designed to spoil you with high-end perks and amenities. Concierge assistance, premium toiletries and fine dining are typically included at these deluxe properties.