Title: The 10 Best 4 Star Hotels in Florida Keys - 2026 Updated Prices | Expedia.co.uk [Florida Keys Travel Guide](https://expedia.co.uk/Florida-Keys.dx6023765)[Hotels in Florida Keys](https://expedia.co.uk/Florida-Keys-Hotels.d6023765.Travel-Guide-Hotels)[Holiday Rentals in Florida Keys](https://expedia.co.uk/Florida-Keys-Holiday-Rentals.d6023765.Travel-Guide-HolidayRentals)[Flights to Florida Keys](https://expedia.co.uk/Cheap-Flights-To-Florida-Keys.d6023765.Travel-Guide-Flights)[Things to do in Florida Keys](https://expedia.co.uk/Things-To-Do-In-Florida-Keys.d6023765.Travel-Guide-Activities)[Florida Keys Car Hire](https://expedia.co.uk/Compare-Cheap-Car-Hire-In-Florida-Keys.d6023765.Car-Hire-Guide)[Florida Keys Holidays](https://expedia.co.uk/Florida-Keys.d6023765.Holidays-City-Breaks) ![](https://images.trvl-media.com/place/6246822/f00ad239-b8ad-4f0c-b162-acc6426db1e2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6246822/f00ad239-b8ad-4f0c-b162-acc6426db1e2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save instantly and earn perks with One Key [Learn about One Key](https://www.expedia.co.uk/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Florida Keys 4 Star Hotels Tonight [30 Mar - 31 Mar](https://www.expedia.co.uk/Hotel-Search?regionId=6023765&startDate=2026-03-30&endDate=2026-03-31&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [31 Mar - 1 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=6023765&startDate=2026-03-31&endDate=2026-04-01&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [3 Apr - 5 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=6023765&startDate=2026-04-03&endDate=2026-04-05&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [10 Apr - 12 Apr](https://www.expedia.co.uk/Hotel-Search?regionId=6023765&startDate=2026-04-10&endDate=2026-04-12&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Florida Keys 4-star hotels ![Private beach, white sand, sun-loungers, beach umbrellas](https://images.trvl-media.com/lodging/1000000/10000/3500/3427/e9f2dff3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/10000/3500/3427/86c2e00e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Poolside bar](https://images.trvl-media.com/lodging/1000000/10000/3500/3427/b2a768a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach views, serves lunch, dinner and happy hour](https://images.trvl-media.com/lodging/1000000/10000/3500/3427/cae52070.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Reefhouse Resort & Marina [](https://www.expedia.co.uk/Key-Largo-Hotels-Reefhouse-Resort-Marina.h3427.Hotel-Information) Key Largo 9.4/10 Exceptional (1,398 reviews) "Clean rooms, nice staff, great beach area." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brittany £284 includes taxes & fees 19 Apr - 20 Apr [](https://www.expedia.co.uk/Key-Largo-Hotels-Reefhouse-Resort-Marina.h3427.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/1000000/20000/14100/14042/7c755dc1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 outdoor pools, pool umbrellas, pool loungers](https://images.trvl-media.com/lodging/1000000/20000/14100/14042/0df3bfb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch LCD TV with satellite channels, TV, iPod dock](https://images.trvl-media.com/lodging/1000000/20000/14100/14042/bbdba544.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 restaurants, breakfast served](https://images.trvl-media.com/lodging/1000000/20000/14100/14042/4de34d26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baker's Cay Resort Key Largo, Curio Collection by Hilton [](https://www.expedia.co.uk/Key-Largo-Hotels-Bakers-Cay-Resort-Key-Largo.h14042.Hotel-Information) Key Largo 8.6/10 Excellent (1,021 reviews) "The resort was beautiful. We really enjoyed our time there." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jessica £326 includes taxes & fees 13 Apr - 14 Apr [](https://www.expedia.co.uk/Key-Largo-Hotels-Bakers-Cay-Resort-Key-Largo.h14042.Hotel-Information) ![Alligator Reef Oceanfront Room King Lanai with Queen Sofabed | View from room](https://images.trvl-media.com/lodging/1000000/70000/62000/61976/4186365f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![One Bedroom Oceanfront Suite Two Queens Lanai | Egyptian cotton sheets, premium bedding, down duvets, pillow-top beds](https://images.trvl-media.com/lodging/1000000/70000/62000/61976/a737b04b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Alligator Reef Oceanfront Room King Lanai with Queen Sofabed | Egyptian cotton sheets, premium bedding, down duvets, pillow-top beds](https://images.trvl-media.com/lodging/1000000/70000/62000/61976/2728b985.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Alligator Reef Oceanfront Room King | Beach/ocean view](https://images.trvl-media.com/lodging/1000000/70000/62000/61976/43c465e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Amara Cay Resort [](https://www.expedia.co.uk/Islamorada-Hotels-Amara-Cay-Resort.h61976.Hotel-Information) Matecumbe 8.8/10 Excellent (1,264 reviews) "Yes the pool was fabulous. The Ocean view was quite good for a room that was not ocean front." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joseph £258 includes taxes & fees 19 Apr - 20 Apr [](https://www.expedia.co.uk/Islamorada-Hotels-Amara-Cay-Resort.h61976.Hotel-Information) ![5 outdoor pools, pool cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/1000000/10000/6100/6068/8671ba74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/1000000/10000/6100/6068/3c4550e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/1000000/10000/6100/6068/7a4a0bef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/1000000/10000/6100/6068/306bb501.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hawks Cay Resort [](https://www.expedia.co.uk/Marathon-Hotels-Hawks-Cay-Resort.h6068.Hotel-Information) Marathon 8.0/10 Very good (1,008 reviews) "4.5 of 5 stars - very nice resort" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robert £334 includes taxes & fees 26 Apr - 27 Apr [](https://www.expedia.co.uk/Marathon-Hotels-Hawks-Cay-Resort.h6068.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/480000/475500/475438/f8d2863e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 restaurants, breakfast served](https://images.trvl-media.com/lodging/1000000/480000/475500/475438/d49c45e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/1000000/480000/475500/475438/7f55fd9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 restaurants, breakfast served](https://images.trvl-media.com/lodging/1000000/480000/475500/475438/2bff44ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Islander Resort [](https://www.expedia.co.uk/Islamorada-Hotels-Islander-Resort.h475438.Hotel-Information) Matecumbe 9.2/10 Wonderful (1,007 reviews) "Wonderful stay. Staff, rooms, grounds, food were all excellent." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kim £305 includes taxes & fees 22 Apr - 23 Apr [](https://www.expedia.co.uk/Islamorada-Hotels-Islander-Resort.h475438.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/12000000/11920000/11919100/11919055/8c74658c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Serves lunch and dinner](https://images.trvl-media.com/lodging/12000000/11920000/11919100/11919055/bb9d7ce2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/12000000/11920000/11919100/11919055/ba58782b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![On the beach, beach cabanas, sun-loungers, beach umbrellas](https://images.trvl-media.com/lodging/12000000/11920000/11919100/11919055/d9cc2f68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Playa Largo Resort & Spa, Autograph Collection [](https://www.expedia.co.uk/Key-Largo-Hotels-Playa-Largo-Resort-Spa.h11919055.Hotel-Information) Rock Harbor 8.8/10 Excellent (1,006 reviews) "Overall wonderful resort and great location. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kristie Howle £380 includes taxes & fees 13 Apr - 14 Apr [](https://www.expedia.co.uk/Key-Largo-Hotels-Playa-Largo-Resort-Spa.h11919055.Hotel-Information) ![In-room safe, individually decorated, individually furnished](https://images.trvl-media.com/lodging/1000000/20000/11900/11864/4671ebc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/11900/11864/w4000h2663x0y0-d63f21e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Double Bed, Balcony, Oceanfront | Living area | 37-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/1000000/20000/11900/11864/ab6da82f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Banquet hall](https://images.trvl-media.com/lodging/1000000/20000/11900/11864/cb9f9f1a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort [](https://www.expedia.co.uk/Islamorada-Hotels-Three-Waters-Resort-And-Marina.h11864.Hotel-Information) Islamorada 9.0/10 Wonderful (179 reviews) "Very, very good architectural design and construction. And a well-maintained facility." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) roy steven £367 includes taxes & fees 19 Apr - 20 Apr [](https://www.expedia.co.uk/Islamorada-Hotels-Three-Waters-Resort-And-Marina.h11864.Hotel-Information) ![Suite, 1 King Bed with Sofa bed, Ocean View | Egyptian cotton sheets, premium bedding, pillow-top beds, in-room safe](https://images.trvl-media.com/lodging/3000000/2480000/2477600/2477508/18023e21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool loungers](https://images.trvl-media.com/lodging/3000000/2480000/2477600/2477508/7578de06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed with Sofa bed, Ocean View | Exterior](https://images.trvl-media.com/lodging/3000000/2480000/2477600/2477508/b304e7ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2480000/2477600/2477508/c134a889.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Siesta Resort & Villas [](https://www.expedia.co.uk/Islamorada-Hotels-La-Siesta-Resort-Marina.h2477508.Hotel-Information) Matecumbe 8.6/10 Excellent (1,003 reviews) "We had a enjoyable stay here and would come back again if we were ever in the area. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) angela £226 includes taxes & fees 29 Apr - 30 Apr [](https://www.expedia.co.uk/Islamorada-Hotels-La-Siesta-Resort-Marina.h2477508.Hotel-Information) ![3 outdoor pools, pool loungers](https://images.trvl-media.com/lodging/1000000/120000/117100/117099/854776a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gazebo](https://images.trvl-media.com/lodging/1000000/120000/117100/117099/c4d130ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/120000/117100/117099/92bf29ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Villa, Multiple Beds, Beachfront | Premium bedding, pillow-top beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/120000/117100/117099/f82dd976.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tranquility Bay Beachfront Hotel and Resort [](https://www.expedia.co.uk/Marathon-Hotels-Tranquility-Bay-Beachfront-Hotel-And-Resort.h117099.Hotel-Information) Marathon 8.8/10 Excellent (1,005 reviews) "Amazing resort " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joy £457 includes taxes & fees 22 Apr - 23 Apr [](https://www.expedia.co.uk/Marathon-Hotels-Tranquility-Bay-Beachfront-Hotel-And-Resort.h117099.Hotel-Information) ![5 outdoor pools, pool cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/100000000/99930000/99920100/99920083/8638cc9f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![LCD TV](https://images.trvl-media.com/lodging/100000000/99930000/99920100/99920083/791c447b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/100000000/99930000/99920100/99920083/4823618c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![LCD TV](https://images.trvl-media.com/lodging/100000000/99930000/99920100/99920083/471fc6ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Villas At Hawks Cay Resort [](https://www.expedia.co.uk/Villas-At-Hawks-Cay-Resort.h99920083.Hotel-Information) Marathon 8.2/10 Very good (183 reviews) "We had a great stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Elise [](https://www.expedia.co.uk/Villas-At-Hawks-Cay-Resort.h99920083.Hotel-Information) ![Balcony view](https://images.trvl-media.com/lodging/37000000/36890000/36881900/36881801/d5720c3e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach bar](https://images.trvl-media.com/lodging/37000000/36890000/36881900/36881801/ef4dc63f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Balcony view](https://images.trvl-media.com/lodging/37000000/36890000/36881900/36881801/4d5bbaec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/37000000/36890000/36881900/36881801/1b2eda02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Grassy Flats Resort & Beach Club [](https://www.expedia.co.uk/Marathon-Hotels-Grassy-Flats-Resort-Beach-Club.h36881801.Hotel-Information) Marathon 9.4/10 Exceptional (421 reviews) "Yes the view was nice, the hotel staff was nice and the room was clean" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) DEBORAH LEE £279 includes taxes & fees 29 Apr - 30 Apr [](https://www.expedia.co.uk/Marathon-Hotels-Grassy-Flats-Resort-Beach-Club.h36881801.Hotel-Information) ![On the beach, sun-loungers, beach umbrellas, beach towels](https://images.trvl-media.com/lodging/55000000/54780000/54774300/54774228/dd7d4fab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Balcony view](https://images.trvl-media.com/lodging/55000000/54780000/54774300/54774228/55a08207.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Balcony view](https://images.trvl-media.com/lodging/55000000/54780000/54774300/54774228/95dbc957.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillow-top beds, in-room safe, individually decorated](https://images.trvl-media.com/lodging/55000000/54780000/54774300/54774228/a064415d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Islands of Islamorada [](https://www.expedia.co.uk/Islamorada-Hotels-The-Islands-Of-Islamorada.h54774228.Hotel-Information) Matecumbe 9.8/10 Exceptional (73 reviews) "This place exceeded my expectations. Such a beautiful and quiet setting. Don't want to leave, but I will definitely be backa a beautiful " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Beth £635 includes taxes & fees 13 Apr - 14 Apr [](https://www.expedia.co.uk/Islamorada-Hotels-The-Islands-Of-Islamorada.h54774228.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/112000000/111880000/111875800/111875758/8a6bf167.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111880000/111875800/111875758/dd229945.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Villa | Living area | 42-inch flat-screen TV with cable channels, ping pong](https://images.trvl-media.com/lodging/112000000/111880000/111875800/111875758/4a7aaa36.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/112000000/111880000/111875800/111875758/9a7a2044.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Reef at Marathon, Florida Keys [](https://www.expedia.co.uk/Marathon-Hotels-The-Reef-At-Marathon.h111875758.Hotel-Information) Marathon 9.2/10 Wonderful (15 reviews) "Absolutely LOVED this place!! Affordable rates first of all, clean! Arrived late for check in and it was a quick smooth process, friendly staff. Definitely going back! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Angie [](https://www.expedia.co.uk/Marathon-Hotels-The-Reef-At-Marathon.h111875758.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/117000000/116450000/116443200/116443145/cf2fb1a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/117000000/116450000/116443200/116443145/e892f572.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Townhome, Marina View | Balcony](https://images.trvl-media.com/lodging/117000000/116450000/116443200/116443145/564903d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Townhome, Marina View | Living area | Flat-screen TV](https://images.trvl-media.com/lodging/117000000/116450000/116443200/116443145/3bb980c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Marlin Bay Resort & Marina [](https://www.expedia.co.uk/Marathon-Hotels-Marlin-Bay-Resort-Marina.h116443145.Hotel-Information) Marathon 10/10 Exceptional (2 reviews) "Wonderful vacation!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chardell [](https://www.expedia.co.uk/Marathon-Hotels-Marlin-Bay-Resort-Marina.h116443145.Hotel-Information) ![Luxury Villa, 3 Bedrooms, Balcony, Overwater | Terrace/patio](https://images.trvl-media.com/lodging/121000000/120660000/120656300/120656286/378f248d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/121000000/120660000/120656300/120656286/680a0471.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/121000000/120660000/120656300/120656286/e487d931.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/121000000/120660000/120656300/120656286/784969bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Waterfront Luxury Villa [](https://www.expedia.co.uk/Marathon-Hotels-Waterfront-Luxury-Villa.h120656286.Hotel-Information) Marathon Shores [](https://www.expedia.co.uk/Marathon-Hotels-Waterfront-Luxury-Villa.h120656286.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/61000000/60290000/60289900/60289884/7d71db4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lake](https://images.trvl-media.com/lodging/61000000/60290000/60289900/60289884/1d5cc14d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/61000000/60290000/60289900/60289884/4c18eaad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, Multiple Beds, Private Pool, Garden View | Living room | TV](https://images.trvl-media.com/lodging/61000000/60290000/60289900/60289884/b7e4c2f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Caribbean Resort Coconut Palm North [](https://www.expedia.co.uk/Islamorada-Hotels-The-Caribbean-Resort-Hemingway-House-North.h60289884.Hotel-Information) Matecumbe [](https://www.expedia.co.uk/Islamorada-Hotels-The-Caribbean-Resort-Hemingway-House-North.h60289884.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.co.uk/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Florida-Keys-Hotels.s40-0-d6023765.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.co.uk/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Florida-Keys-Hotels.s40-0-d6023765.Travel-Guide-Filter-Hotels) ## Explore similar 5-star hotels Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Florida Keys. ![Cheeca Lodge & Spa](https://images.trvl-media.com/lodging/1000000/10000/5800/5780/4608d7e2_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Cheeca Lodge & Spa 81801 Overseas Highway, Mile Marker 82 Islamorada FL £276 29 Apr - 30 Apr includes taxes & fees 9.2/10 Wonderful! (1,304 reviews) [](https://expedia.co.uk/Islamorada-Hotels-Cheeca-Lodge-Spa.h5780.Hotel-Information) ![Isla Bella Beach Resort & Spa](https://images.trvl-media.com/lodging/25000000/24110000/24101800/24101706/f6566b0f_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Isla Bella Beach Resort & Spa 1 Knights Key Boulevard Marathon FL £359 26 Apr - 27 Apr includes taxes & fees 9.2/10 Wonderful! (1,113 reviews) [](https://expedia.co.uk/Marathon-Hotels-Isla-Bella-Beach-Resort-Spa.h24101706.Hotel-Information) Still don't see what you're looking for? [See all properties in Florida Keys.](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=31%2F03%2F2026&endDate=01%2F04%2F2026®ionId=6023765&star=40) You can also use these popular filters to refine your search. [Pool](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=31%2F03%2F2026&endDate=01%2F04%2F2026®ionId=6023765&star=40&star=40&amenities=POOL)[Spa](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=31%2F03%2F2026&endDate=01%2F04%2F2026®ionId=6023765&star=40&star=40&amenities=SPA_ON_SITE)[Hot tub](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=31%2F03%2F2026&endDate=01%2F04%2F2026®ionId=6023765&star=40&star=40&amenities=HOT_TUB)[Breakfast included](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=31%2F03%2F2026&endDate=01%2F04%2F2026®ionId=6023765&star=40&star=40&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.co.uk/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=31%2F03%2F2026&endDate=01%2F04%2F2026®ionId=6023765&star=40&star=40&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about Florida Keys Snorkel crystal-clear waters teeming with colourful fish, then feast on fresh-caught lobster at a laid-back waterfront shack. Drive the scenic Overseas Highway, stopping at Key West's Ernest Hemingway Home and Dry Tortugas National Park for island adventures. [See all hotels in Florida Keys](https://www.expedia.co.uk/Hotel-Search?startDate=2026-04-13&endDate=2026-04-14&adults=2®ionId=6023765) ![](https://images.trvl-media.com/place/6246822/f00ad239-b8ad-4f0c-b162-acc6426db1e2.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high) ## Top Florida Keys Hotel Reviews ![Baker's Cay Resort Key Largo, Curio Collection by Hilton](https://images.trvl-media.com/lodging/1000000/20000/14100/14042/7c755dc1_y.jpg) ### Baker's Cay Resort Key Largo, Curio Collection by Hilton 10/10 Excellent "Very good. " [](https://expedia.co.uk/Key-Largo-Hotels-Bakers-Cay-Resort-Key-Largo.h14042.Hotel-Information) ![Hawks Cay Resort](https://images.trvl-media.com/lodging/1000000/10000/6100/6068/8671ba74_y.jpg) ### Hawks Cay Resort 10/10 Excellent "Staff were friendly and helpful. My family enjoyed the pools and Lagoon. We also enjoyed the marina and the restaurants on the resort." [](https://expedia.co.uk/Marathon-Hotels-Hawks-Cay-Resort.h6068.Hotel-Information) ![Amara Cay Resort](https://images.trvl-media.com/lodging/1000000/70000/62000/61976/4186365f_y.jpg) ### Amara Cay Resort 10/10 Excellent "Property was truly beautiful with friendly staff and amazing amenities. The free shuttle to the other resorts was a great surprise as well. We took the Rum Runner for breakfast (shout out to Captain Dave and Bruce for being amazing). In my opinion, Amara Cay was the nicest of the three resorts if you’re looking for island luxury and a truly relaxing experience. Will definitely be visiting again!" [](https://expedia.co.uk/Islamorada-Hotels-Amara-Cay-Resort.h61976.Hotel-Information) ## Find out more about Florida Keys ## Pocket Guide: 4 Stars Hotels in Florida Keys ### 4 Star Luxury in the Florida Keys You’ll find a great selection of four-star hotels in [Florida Keys](https://www.expedia.co.uk/Florida-Keys-Hotels.d6023765.Travel-Guide-Hotels), each reflecting its very own character, charm and ethos. Whatever the style, whether it’s an elegant resort and spa, contemporary seaside hotel or plush cottage, most four-star accommodation in the Florida Keys are close to the water, and you wouldn’t want it any other way. For the true magic of the Florida Keys is in its beaches, coral reefs and Gulf of Mexico views. ### Where Are Florida Keys’ 4 Star Hotels? Key West is home to most of Florida Keys’ four-star resorts. With Mallory Square Plaza, beautiful beaches, its historic old town and a world-class golf course, [Key West](https://www.expedia.co.uk/Key-West-Hotels.d1187.Travel-Guide-Hotels) is one of the most idyllic places to stay. You’ll also find luxury accommodation on Islamorada, as well as the lesser-visited islands of Little Torch Key and the romantic Marathon Island. With swimming pools, sea views and palm trees (not to mention the spas and fine-dining restaurants) it will be hard to drag yourself away from your four-star hotel to explore. ### Enjoy the Florida Keys in Style Looking out to sea is one thing, but for an experience you won’t quickly forget, get out on to the water in comfort aboard your very own yacht for the day and explore hidden beaches and clear coves. You can charter catamarans, sail or motorboats from many of the islands’ marinas or through your hotel concierge. Anglers, whether novices or long-time enthusiasts, will find the waters teeming with big-game fish. Or why not learn a new water sport? Scuba-diving courses are a wonderful experience and will introduce you to a whole new world beneath the waves. If you’re more of a land-lubber than a budding mariner, hunker down by one of the oasis-like pools in your hotel with a fruit rum cocktail in hand and ease in to your stay. Museums such as the Ernest Hemingway House, art galleries and cigar rooms are local institutions and give you an insight into the culture and history of the Florida Keys. ## Frequently asked questions ### What are the best 4-star hotels in Florida Keys? ### How much does it cost to stay in a 4-star hotel in Florida Keys? > - Search for the lowest price from £276 ### What's the difference between 5-star and 4-star hotels in Florida Keys? ## Explore a world of travel with Expedia - Accommodation - Packages - More ways to book - [Hotels near John Pennekamp Coral Reef State Park ](https://www.expedia.co.uk/John-Pennekamp-Coral-Reef-State-Park-Hotels.0-l6068611-0.Travel-Guide-Filter-Hotels) - [John Pennekamp Coral Reef State Park ](https://www.expedia.co.uk/John-Pennekamp-Coral-Reef-State-Park-United-States-of-America.d6068611.Attraction) - [Book 4 Star Hotels in Florida Keys on Expedia.com ](https://www.expedia.com/4Star-Florida-Keys-Hotels.s40-0-d6023765.Travel-Guide-Filter-Hotels)