The Best Hotels Closest to Louisville Science Center in Louisville - 2026 Updated Prices

The entrance to the Kentucky Science Center with a large circular structure in the foreground.

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Our top choices for Louisville Science Center hotels

A modern hotel lobby with a reception desk, seating area, and a staircase leading to the upper floor.

A modern, well-lit room with a large bed, a green sofa, a small round table, and a kitchen area in the background.

A modern interior with a green wall, black chairs, and a ceiling with exposed beams and lights.

A modern bedroom with a bed, a blue sofa, a large rug, and a TV on the wall.

1. Stellar Suites

East Market District, 1.4 mi from Louisville Science Center

Benton

£120

includes taxes & fees

29 Sept - 30 Sept

A modern interior with a fireplace, bookshelves, a green sofa, and leather chairs.

A modern hotel room with a large bed, a desk with a flat-screen TV, a green armchair, and a view of the city through large windows.

A modern restaurant interior with a staircase, round tables, and a brick wall.

A multi-level interior with a staircase, bookshelves, and a prominent sign reading "THE GRADY".

2. The Grady

Downtown Louisville, 0.1 mi from Louisville Science Center

Bruce

£136

includes taxes & fees

13 Sept - 14 Sept

A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.

A modern building entrance with a glass facade, wooden ceiling, and illuminated fixtures.

A lobby with a marble floor, a reception desk, and a large chandelier.

A rooftop bar with outdoor seating, including sofas and chairs, and a bar area with a television screen.

3. Omni Louisville Hotel

Downtown Louisville, 0.5 mi from Louisville Science Center

Kara

£161

includes taxes & fees

13 Sept - 14 Sept

A bar area with a neon 'CHECK IN' sign, a variety of liquor bottles, and a modern seating arrangement.

A modern hotel room with a large bed, a desk with a chair, a TV mounted on the wall, and a window with a city view.

A modern hotel with a prominent 'Marriott' sign, large windows, and a brick facade.

A cozy living room with a fireplace, a black leather sofa, and a patterned rug.

4. Moxy Louisville Downtown

Downtown Louisville, 0.6 mi from Louisville Science Center

Harry

£78

includes taxes & fees

4 Oct - 5 Oct

A brick building with outdoor seating and a fire pit.

A modern restaurant with wooden furniture, a central island, and a high ceiling.

A modern bar area with a wooden counter, bar stools, and a variety of bottles and glasses.

A modern hotel room with a sofa, a small desk, a microwave, and a TV.

5. TownePlace Suites by Marriott Louisville North

1.4 mi from Louisville Science Center

Lisa

£116

includes taxes & fees

11 Oct - 12 Oct

An indoor dining area with wooden tables and chairs, a bar area, and a view of the street outside.

A modern hotel with a prominent 'Aloft Hotels' sign, multiple floors, and a corner location with a view of the city skyline.

A modern lounge area with a pool table, comfortable seating, a fireplace, and a brick accent wall.

A modern coffee shop interior with a central island, wooden counter, and large windows.

6. Aloft by Marriott Louisville Downtown

Downtown Louisville, 0.6 mi from Louisville Science Center

Angela

£122

includes taxes & fees

4 Oct - 5 Oct

A modern interior with large windows offering a city view, a circular light fixture, and leather seating.

A nighttime view of The GALT and The Galthouse buildings with illuminated signage, a busy street with light trails from moving vehicles, and a modern urban setting.

A modern bar with a long counter, multiple shelves of liquor bottles, and cushioned bar stools.

A spacious room with a large dining table, comfortable seating, a sofa, and a view of a bridge.

7. Galt House Hotel Trademark Collection by Wyndham

Downtown Louisville, 0.3 mi from Louisville Science Center

Jacob

£142

includes taxes & fees

5 Oct - 6 Oct

A modern building with a restaurant on the ground floor, featuring large windows and outdoor seating.

A modern hotel room with a large window offering a city view, a cozy seating area with a sofa and chairs, a dining table with lamps, and a wooden floor.

A reception area with marble counters, modern pendant lighting, and potted orchids.

A spacious lobby with a bar area, seating arrangements, and a visible kitchen bar.

8. Louisville Marriott Downtown

Downtown Louisville, 0.5 mi from Louisville Science Center

Chris

£135

includes taxes & fees

13 Sept - 14 Sept

A spacious lobby with a blue sofa, a wooden coffee table, and a chandelier.

An indoor swimming pool with clear water, surrounded by white marble walls and columns, and furnished with lounge chairs and tables.

A hotel dining area with long tables, booths, and a bar.

A modern bar area with a long counter, multiple chairs, and a bookshelf filled with bottles.

9. Embassy Suites Louisville Downtown

Downtown Louisville, 0.5 mi from Louisville Science Center

Maurica

£142

includes taxes & fees

12 Oct - 13 Oct

A covered patio with a stone wall, a glass table, and a bench.

A grand room with a fireplace, a staircase, and a chandelier.

A garden pathway with a lantern, potted plants, and a white fence.

10. Central Park Bed & Breakfast

Old Louisville, 1.8 mi from Louisville Science Center

Angie

£130

includes taxes & fees

22 Sept - 23 Sept

A spacious lobby with a central escalator, comfortable seating areas, and modern lighting fixtures.

A modern living room with a sofa, armchairs, a coffee table, and a dining area with a table and chairs.

An outdoor seating area with wicker furniture, wooden tables, and large lamps.

A modern lobby with a central seating area, an escalator, and a staircase.

11. Hyatt Regency Louisville

Downtown Louisville, 0.4 mi from Louisville Science Center

Arnetta

£157

includes taxes & fees

15 Sept - 16 Sept

A historic hotel with ornate architecture, a grand entrance, and a red carpet leading to the doors.

A grand staircase with ornate railings and a marble floor, leading to a high-ceilinged lobby with decorative moldings and a chandelier.

A spacious living room with a fireplace, wooden paneling, a television, and a blue sofa.

A grand lobby with marble floors, a staircase, and a reception desk.

12. Seelbach Hilton Louisville Downtown

Downtown Louisville, 0.5 mi from Louisville Science Center

Jennifer

£156

includes taxes & fees

13 Sept - 14 Sept

A Courtyard by Marriott hotel with a modern brick facade, multiple floors, and a prominent sign.

A modern hotel lobby with a large seating area, a flat-screen TV, and a large window with sheer curtains.

A modern living room with a fireplace, comfortable seating, and a large TV.

A modern bistro with a wooden counter, menu boards, and seating area with tables and chairs.

13. Courtyard by Marriott Louisville Downtown

Downtown Louisville, 0.5 mi from Louisville Science Center

sabrina

£127

includes taxes & fees

1 Oct - 2 Oct

A spacious lobby with leather sofas, round tables, and ottomans, featuring large windows and modern lighting fixtures.

A conference room with a large table, multiple chairs, a projector screen, and a small bar area.

A hotel with a brick facade, multiple floors, and a prominent signage.

A grocery store with refrigerated freezers, shelves stocked with beverages, snacks, and household items.

14. Residence Inn by Marriott Louisville Downtown

Downtown Louisville, 0.9 mi from Louisville Science Center

Kooper

£113

includes taxes & fees

12 Oct - 13 Oct

An outdoor seating area with wicker furniture and a fire pit.

An indoor swimming pool with clear water, a diving board, and lounge chairs around the pool area.

A modern lounge area with seating, tables, and a view of the city through large windows.

A modern living room with a sofa, armchairs, a coffee table, and a TV.

15. Towneplace Suites By Marriott Louisville Downtown

Downtown Louisville, 0.2 mi from Louisville Science Center

Tina

£103

includes taxes & fees

5 Oct - 6 Oct

A modern kitchen with wooden cabinets, a long countertop, and a variety of food items displayed.

A modern lobby with a curved ceiling, a black sofa with red cushions, a red chair, and a small yellow table.

An outdoor patio area with a wooden pergola, tables, chairs, and potted plants.

A multi-story hotel with a prominent signage for SpringHill Suites Marriott.

16. SpringHill Suites by Marriott Louisville Downtown

Downtown Louisville, 0.7 mi from Louisville Science Center

Brittany

£103

includes taxes & fees

12 Oct - 13 Oct

An indoor swimming pool with clear blue water, surrounded by lounge chairs and large windows.

A breakfast bar with a chalkboard menu, a microwave, and various food and drink dispensers.

A bar area with a counter, multiple chairs, and tables. There are framed pictures on the wall and a clock.

A hotel room with a large bed, a desk with a flat-screen TV, a desk lamp, and a window with curtains.

17. Hampton Inn Louisville Downtown

Downtown Louisville, 0.6 mi from Louisville Science Center

Wen

£89

includes taxes & fees

13 Oct - 14 Oct

A modern restaurant with hanging light fixtures, a bar area, and various seating options.

A modern reception area with a textured wall, a reception desk, multiple seating areas, and pendant lighting.

A hotel lobby with a reception desk, a 'Chilled' beverage fridge, a 'Frozen' section, and a 'The Shop' sign.

A modern living room with sofas, a coffee table, and a TV.

18. Hilton Garden Inn Louisville Downtown

Downtown Louisville, 0.6 mi from Louisville Science Center

Myla

£96

includes taxes & fees

13 Oct - 14 Oct

A modern hotel room with a bed, desk, chair, couch, and a framed picture on the wall.

A person serving food to another person in a kitchen with tiled walls and various cooking utensils.

19. Hyatt Select Louisville North

1.2 mi from Louisville Science Center

William

£83

includes taxes & fees

13 Sept - 14 Sept

A hotel room with two beds, a desk with a lamp, a TV, and a window with curtains.

A hotel room with a large bed, two bedside tables with lamps, a desk, and a window with curtains.

20. Derby Hotel & Suites

1.8 mi from Louisville Science Center

Andrew

£36

includes taxes & fees

13 Sept - 14 Sept

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Compare popular hotels close to Louisville Science Center

Property	Property class	Guest rating
Stellar Suites	9.6 Exceptional 148 reviews	View
The Grady	9.4 Exceptional 1,001 reviews	View
Omni Louisville Hotel	9.4 Exceptional 2,129 reviews	View
Moxy Louisville Downtown	9.2 Wonderful 835 reviews	View
TownePlace Suites by Marriott Louisville North	9.2 Wonderful 727 reviews	View

Top Louisville Science Center Hotel Reviews

Moxy Louisville Downtown

10/10 Excellent

"Nice experience"

SpringHill Suites by Marriott Louisville Downtown

8/10 Good

"We had a good experience overall. The location is excellent, everything was clean, and the staff was very friendly and welcoming. However, we were disappointed with the breakfast service. Breakfast is listed as available until 10:00 AM, but when we arrived at 9:45 AM, everything was already packed up and cleared away, leaving us with no breakfast."

Hyatt Regency Louisville

10/10 Excellent

"The staff was lovely and very accommodating. The entire hotel was very clean and well maintained. The beds were so comfortable that I wanted to take them home with me. We really enjoyed the bread pudding at the breakfast buffet, use of the pool, and it was so convenient having a Starbucks located inside. Would absolutely book again."

Embassy Suites Louisville Downtown

10/10 Excellent

"Absolutely"

Radisson Hotel Louisville North

10/10 Excellent

"❤️❤️"

Louisville Marriott Downtown

10/10 Excellent

"Front desk staff awesome"

The Brown Hotel

10/10 Excellent

"What a fantastic hotel! It was raining, so we didn’t get to walk around much, so we stayed in the hotel for drinks and dinner. Both were wonderful!"

Homewood Suites by Hilton Louisville Downtown, KY

10/10 Excellent

"By far our favorite place we stayed at. Will definitely become our go to when we drive across country"

21c Museum Hotel Louisville

8/10 Good

"This is a very nice hotel, with clean comfortable rooms and plush beds. Front desk was very helpful with local recommendations. I liked the quirkiness of the property, but the overall vibe is definitely more 'adult'. Our kids loved the screen by the elevators, but the other art was a bit off-putting for younger families. Also, there was plenty of room in there to make those beds queen-sized!"

Other attractions near Louisville Science Center

A wall of wooden baseball bats organized by size and weight.

Louisville Slugger Museum

9.2/10 (2,299 reviews)

Baseball is part of the American fabric. See where one important tool for this sport is produced in the factory that makes ball games possible.

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A modern building with a cylindrical structure and a glass facade.

Muhammad Ali Center

8.8/10 (295 reviews)

One of the world’s greatest boxers continues providing inspiration beyond the world of sport. Understand this superstar by visiting this center honoring him.

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The Frazier History Museum with red doors and a tree in front.

Frazier International History Museum

9.4/10 (10 reviews)

Get to know Louisville with a visit to this esteemed museum. It’s a great spot for social interaction as well.

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Kentucky Center for the Performing Arts

8.8/10 (49 reviews)

Enjoy a pleasant night at the opera or attend a concert, live dance or stage production at this glass-fronted venue in downtown Louisville.

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Kentucky Museum of Art and Craft

You can spend an afternoon exploring the galleries in Kentucky Museum of Art and Craft during your trip to Louisville. Stroll along the area's riverfront or experience its lively festivals.

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Golden Statue of David

Find out about the history of Louisville when you spend time at Golden Statue of David. Attend a sporting event or simply enjoy the lively bars while you're in the area.

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SAR Genealogical Research Library: NSSAR Library

You can spend time exploring the galleries in SAR Genealogical Research Library: NSSAR Library in Louisville. Amble around this family-friendly area's riverfront and enjoy its top-notch restaurants.

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Louisville Glassworks

You can spend an afternoon browsing the exhibits at Louisville Glassworks in Louisville. Experience the area's lively festivals or attend a sporting event.

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Frequently asked questions

What's the area like around Louisville Science Center?

Louisville Science Center is located in an area of Louisville known for its stunning river views, sporting events and great live music scene. If you're looking for a convenient place to stay, take a look at the 292 hotels and other accommodation options you'll find within a mile.

Where is the best place to stay near Louisville Science Center?

Adjacent to Louisville Science Center, Holiday Inn Express & Suites Louisville Downtown by IHG is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and a 24-hour fitness centre. Other good choices within a short distance include Galt House Hotel Trademark Collection by Wyndham and Omni Louisville Hotel.

How many hotels can I expect to find close to Louisville Science Center?

Expedia has 292 hotels and other accommodation options within a mile from Louisville Science Center.

If I need to cancel the hotel reservation for my stay near Louisville Science Center, will I receive a refund?

Yes! Most hotel room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of check in. If you booked a non-refundable reservation, you might be able to still cancel and get a refund within a 24-hour period of booking. Add dates, click "Search", then use the filter option "fully refundable" to get the top deals on offer near Louisville Science Center.

What can I see and do near Louisville Science Center?

21c Museum Hotel, Louisville Slugger Museum and Muhammad Ali Center feature a variety of fascinating exhibits to see while you're in town. Explore landmarks like Belle of Louisville, Whiskey Row and Historic Frankfort Avenue. You can catch a show at Louisville Palace, Derby Dinner Playhouse and Headliners Music Hall.

Search Hotels Near Louisville Science Center, Louisville

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Our top choices for Louisville Science Center hotels

1. Stellar Suites

2. The Grady

3. Omni Louisville Hotel

4. Moxy Louisville Downtown

5. TownePlace Suites by Marriott Louisville North

6. Aloft by Marriott Louisville Downtown

7. Galt House Hotel Trademark Collection by Wyndham

8. Louisville Marriott Downtown

9. Embassy Suites Louisville Downtown

10. Central Park Bed & Breakfast

11. Hyatt Regency Louisville

12. Seelbach Hilton Louisville Downtown

13. Courtyard by Marriott Louisville Downtown

14. Residence Inn by Marriott Louisville Downtown

15. Towneplace Suites By Marriott Louisville Downtown

16. SpringHill Suites by Marriott Louisville Downtown

17. Hampton Inn Louisville Downtown

18. Hilton Garden Inn Louisville Downtown

19. Hyatt Select Louisville North

20. Derby Hotel & Suites

Compare popular hotels close to Louisville Science Center

Top Louisville Science Center Hotel Reviews

Moxy Louisville Downtown

SpringHill Suites by Marriott Louisville Downtown

Hyatt Regency Louisville

Embassy Suites Louisville Downtown

Radisson Hotel Louisville North

Louisville Marriott Downtown

The Brown Hotel

Homewood Suites by Hilton Louisville Downtown, KY

21c Museum Hotel Louisville

Other attractions near Louisville Science Center

Louisville Slugger Museum

Muhammad Ali Center

Frazier International History Museum

Kentucky Center for the Performing Arts

Kentucky Museum of Art and Craft

Golden Statue of David

SAR Genealogical Research Library: NSSAR Library

Louisville Glassworks

Frequently asked questions